| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1007/S00018-015-1996-X |
| P698 | PubMed publication ID | 26210153 |
| P50 | author | Erin Thornell | Q85650091 |
| P2093 | author name string | Andrew Aquilina | |
| P2860 | cites work | Cell death triggered by a novel mutation in the alphaA-crystallin gene underlies autosomal dominant cataract linked to chromosome 21q | Q24295954 |
| Autosomal dominant congenital cataract associated with a missense mutation in the human alpha crystallin gene CRYAA | Q24310410 | ||
| A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy | Q24311671 | ||
| Crystal structures of alpha-crystallin domain dimers of alphaB-crystallin and Hsp20 | Q24318942 | ||
| Shotgun identification of protein modifications from protein complexes and lens tissue | Q24534333 | ||
| Four small Drosophila heat shock proteins are related to each other and to mammalian alpha-crystallin | Q24632590 | ||
| In vivo acetylation identified at lysine 70 of human lens alphaA-crystallin | Q24673008 | ||
| Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function | Q27661297 | ||
| Solid-state NMR and SAXS studies provide a structural basis for the activation of αB-crystallin oligomers | Q27664218 | ||
| Crystal Structure of R120G Disease Mutant of Human αB-Crystallin Domain Dimer Shows Closure of a Groove | Q27666994 | ||
| N-terminal domain of B-crystallin provides a conformational switch for multimerization and structural heterogeneity | Q27667422 | ||
| Multiple molecular architectures of the eye lens chaperone B-crystallin elucidated by a triple hybrid approach | Q27675996 | ||
| The major in vivo modifications of the human water-insoluble lens crystallins are disulfide bonds, deamidation, methionine oxidation and backbone cleavage | Q28142819 | ||
| Inhibition of proteasomes induces accumulation, phosphorylation, and recruitment of HSP27 and alphaB-crystallin to aggresomes | Q28211937 | ||
| Post-translational modifications of water-soluble human lens crystallins from young adults | Q28252928 | ||
| In vivo carbamylation and acetylation of water-soluble human lens alphaB-crystallin lysine 92 | Q28365658 | ||
| Decreased Molecular Chaperone Property of α-Crystallins Due to Posttranslational Modifications | Q54367874 | ||
| Phosphorylation of Ser45 and Ser59 of αB-crystallin and p38/extracellular regulated kinase activity determine αB-crystallin-mediated protection of rat brain astrocytes from C2-ceramide- and staurosporine-induced cell death. | Q54369374 | ||
| Clinical variability of autosomal dominant cataract, microcornea and corneal opacity and novel mutation in the alpha A crystallin gene (CRYAA). | Q55048840 | ||
| Alpha B-crystallin mutation in dilated cardiomyopathy | Q55671182 | ||
| A nonsense mutation (W9X) in CRYAA causes autosomal recessive cataract in an inbred Jewish Persian family | Q55984320 | ||
| The p.G154S mutation of the alpha-B crystallin gene (CRYAB) causes late-onset distal myopathy | Q57390077 | ||
| αB-Crystallin mutation in dilated cardiomyopathies: Low prevalence in a consecutive series of 200 unrelated probands | Q58910689 | ||
| Alpha B-Crystallin, a New Independent Marker for Poor Prognosis in Head and Neck Cancer | Q59160442 | ||
| The reaction of citraconic anhydride with bovine alpha-crystallin lysine residues. Surface probing and dissociation-reassociation studies | Q69942057 | ||
| alpha-crystallin stabilizes actin filaments and prevents cytochalasin-induced depolymerization in a phosphorylation-dependent manner | Q71857993 | ||
| An atypical form of alphaB-crystallin is present in high concentration in some human cataractous lenses. Identification and characterization of aberrant N- and C-terminal processing | Q73133800 | ||
| Modifications of the water-insoluble human lens alpha-crystallins | Q73151150 | ||
| Does post-translational modification influence chaperone-like activity of alpha-crystallin? I. Study on phosphorylation | Q73495509 | ||
| Post-translational modification of alphaB-crystallin of normal human lens | Q73519808 | ||
| Hierarchy of lens proteins requiring protection against heat-induced precipitation by the alpha crystallin chaperone | Q74177363 | ||
| Binding of the stress protein alpha B-crystallin to cardiac myofibrils correlates with the degree of myocardial damage during ischemia/reperfusion in vivo | Q77306397 | ||
| Chaperone activity in the lens | Q77936358 | ||
| Identification of a CRYAB mutation associated with autosomal dominant posterior polar cataract in a Chinese family | Q80024716 | ||
| Nuclear import of {alpha}B-crystallin is phosphorylation-dependent and hampered by hyperphosphorylation of the myopathy-related mutant R120G | Q81133284 | ||
| Identification of protein modifications using MS/MS de novo sequencing and the OpenSea alignment algorithm | Q81637158 | ||
| A novel fan-shaped cataract-microcornea syndrome caused by a mutation of CRYAA in an Indian family | Q83878538 | ||
| Phosphorylation of alpha-crystallin in rat lenses is stimulated by H2O2 but phosphorylation has no effect on chaperone activity | Q28582259 | ||
| Alpha-crystallin can function as a molecular chaperone | Q29618672 | ||
| The eye lens chaperone alpha-crystallin forms defined globular assemblies. | Q30489512 | ||
| Tracking pathology with proteomics: identification of in vivo degradation products of alphaB-crystallin | Q30885316 | ||
| Characterization of Covalent Multimers of Crystallins in Aging Human Lenses | Q31026778 | ||
| Existence of deamidated alphaB-crystallin fragments in normal and cataractous human lenses. | Q31139990 | ||
| Phosphorylation-induced change of the oligomerization state of alpha B-crystallin | Q31629257 | ||
| Ser-59 is the major phosphorylation site in alphaB-crystallin accumulated in the brains of patients with Alexander's disease | Q31832181 | ||
| Structural and functional roles of deamidation and/or truncation of N- or C-termini in human alpha A-crystallin | Q33364507 | ||
| Age-related changes in the spatial distribution of human lens alpha-crystallin products by MALDI imaging mass spectrometry | Q33433847 | ||
| Age-dependent deamidation of lifelong proteins in the human lens | Q33522366 | ||
| Identification of crystallin modifications in the human lens cortex and nucleus using laser capture microdissection and CyDye labeling | Q33547400 | ||
| alpha-Crystallin chaperone-like activity and membrane binding in age-related cataracts | Q33989116 | ||
| AlphaB-crystallin is a novel oncoprotein that predicts poor clinical outcome in breast cancer | Q33992717 | ||
| Structural and functional roles of deamidation of N146 and/or truncation of NH2- or COOH-termini in human αB-crystallin. | Q34041520 | ||
| Alpha-B crystallin gene (CRYAB) mutation causes dominant congenital posterior polar cataract in humans | Q34113048 | ||
| An evaluation of confocal versus conventional imaging of biological structures by fluorescence light microscopy | Q34166371 | ||
| Serine 59 phosphorylation of {alpha}B-crystallin down-regulates its anti-apoptotic function by binding and sequestering Bcl-2 in breast cancer cells. | Q34333585 | ||
| Ageing and vision: structure, stability and function of lens crystallins | Q34339776 | ||
| Molecular chaperones and the aging process | Q34438668 | ||
| Alpha B-crystallin in cardiac tissue. Association with actin and desmin filaments | Q34466918 | ||
| Phosphoproteomics characterization of novel phosphorylated sites of lens proteins from normal and cataractous human eye lenses | Q34511275 | ||
| Pseudophosphorylated αB-crystallin is a nuclear chaperone imported into the nucleus with help of the SMN complex | Q34984453 | ||
| Alpha-crystallin | Q35059055 | ||
| Alpha-crystallin/small heat shock protein has autokinase activity | Q35156128 | ||
| Systemic augmentation of alphaB-crystallin provides therapeutic benefit twelve hours post-stroke onset via immune modulation. | Q35164861 | ||
| Spontaneous cyclization of polypeptides with a penultimate Asp, Asn or isoAsp at the N-terminus and implications for cleavage by aminopeptidase | Q35165265 | ||
| Alpha B-crystallin is expressed in non-lenticular tissues and accumulates in Alexander's disease brain | Q35416428 | ||
| Overexpression and abnormal modification of the stress proteins alpha B-crystallin and HSP27 in Alexander disease | Q35833709 | ||
| Human hsp27, Drosophila hsp27 and human alphaB-crystallin expression-mediated increase in glutathione is essential for the protective activity of these proteins against TNFalpha-induced cell death | Q35850943 | ||
| A novel alphaB-crystallin mutation associated with autosomal dominant congenital lamellar cataract | Q36145661 | ||
| Expression of the murine small heat shock proteins hsp 25 and alpha B crystallin in the absence of stress | Q36232367 | ||
| A novel mutation in CRYAA is associated with autosomal dominant suture cataracts in a Chinese family | Q36499609 | ||
| Differential regulation of small heat shock proteins in transgenic mouse models of neurodegenerative diseases | Q36539434 | ||
| alphaB-crystallin protects retinal tissue during Staphylococcus aureus-induced endophthalmitis | Q36539622 | ||
| Alpha B crystallin accumulation is a specific response to Ha-ras and v-mos oncogene expression in mouse NIH 3T3 fibroblasts | Q36684058 | ||
| Hsp27 (HspB1) and alphaB-crystallin (HspB5) as therapeutic targets. | Q36805868 | ||
| Conformational and functional differences between recombinant human lens alphaA- and alphaB-crystallin | Q36847889 | ||
| Age-related changes in human crystallins determined from comparative analysis of post-translational modifications in young and aged lens: does deamidation contribute to crystallin insolubility? | Q36876664 | ||
| Suppression of GFAP toxicity by alphaB-crystallin in mouse models of Alexander disease | Q37128372 | ||
| Small heat shock protein activity is regulated by variable oligomeric substructure. | Q37141508 | ||
| Regulated structural transitions unleash the chaperone activity of αB-crystallin | Q37218406 | ||
| One size does not fit all: the oligomeric states of αB crystallin | Q37398573 | ||
| Alpha B-crystallin is a small heat shock protein | Q37494057 | ||
| Proteomics and phosphoproteomics analysis of human lens fiber cell membranes | Q39479177 | ||
| αB-crystallin, a small heat shock protein, modulates NF-κB activity in a phosphorylation-dependent manner and protects muscle myoblasts from TNF-α induced cytotoxicity | Q39530842 | ||
| The small heat shock protein alphaA-crystallin is expressed in pancreas and acts as a negative regulator of carcinogenesis | Q39708601 | ||
| Cell signaling pathways to alphaB-crystallin following stresses of the cytoskeleton | Q40231216 | ||
| The small heat shock protein alpha B-crystallin is a novel inhibitor of TRAIL-induced apoptosis that suppresses the activation of caspase-3. | Q40470289 | ||
| The small heat shock protein alpha B-crystallin negatively regulates apoptosis during myogenic differentiation by inhibiting caspase-3 activation | Q40715426 | ||
| Mimicking phosphorylation of alphaB-crystallin affects its chaperone activity | Q41084011 | ||
| The small heat-shock protein, alphaB-crystallin, has a variable quaternary structure | Q41633418 | ||
| Subunit exchange of small heat shock proteins. Analysis of oligomer formation of alphaA-crystallin and Hsp27 by fluorescence resonance energy transfer and site-directed truncations | Q41712828 | ||
| alpha B-crystallin gene induction and phosphorylation by MKK6-activated p38. A potential role for alpha B-crystallin as a target of the p38 branch of the cardiac stress response | Q41736665 | ||
| Hypertonic stress induces alpha B-crystallin expression | Q41972992 | ||
| Effect of aging on the chaperone-like function of human alpha-crystallin assessed by three methods | Q42067190 | ||
| Human protein aging: modification and crosslinking through dehydroalanine and dehydrobutyrine intermediates | Q42105203 | ||
| The polydispersity of αB-crystallin is rationalized by an interconverting polyhedral architecture | Q42152394 | ||
| AlphaB crystallin translocation and phosphorylation: signal transduction pathways and preconditioning in the isolated rat heart | Q42509866 | ||
| Refinement of 3D structure of bovine lens alpha A-crystallin | Q42680125 | ||
| Mutations and modifications support a 'pitted-flexiball' model for alpha-crystallin | Q42680131 | ||
| AlphaB-crystallin interacts with intermediate filaments in response to stress | Q42833212 | ||
| Innervation-dependent phosphorylation and accumulation of alphaB-crystallin and Hsp27 as insoluble complexes in disused muscle | Q44120987 | ||
| Mechanism of chaperone function in small heat-shock proteins. Phosphorylation-induced activation of two-mode binding in alphaB-crystallin | Q44279161 | ||
| Mimicking phosphorylation of alphaB-crystallin on serine-59 is necessary and sufficient to provide maximal protection of cardiac myocytes from apoptosis | Q44306740 | ||
| Phosphorylation of alphaB-crystallin alters chaperone function through loss of dimeric substructure | Q44875494 | ||
| Nonenzymatic phosphorylation of tyrosine and serine by ATP is catalyzed by manganese but not magnesium | Q46356806 | ||
| alpha-Crystallin localizes to the leading edges of migrating lens epithelial cells | Q46476357 | ||
| Effect of phosphorylation on alpha B-crystallin: differences in stability, subunit exchange and chaperone activity of homo and mixed oligomers of alpha B-crystallin and its phosphorylation-mimicking mutant | Q46864451 | ||
| Protective and therapeutic role for alphaB-crystallin in autoimmune demyelination | Q46968199 | ||
| The possible role of alpha-crystallins in human senile cataractogenesis | Q47896869 | ||
| Phosphorylations of alpha A- and alpha B-crystallin | Q47896902 | ||
| NMR spectroscopy of alpha-crystallin. Insights into the structure, interactions and chaperone action of small heat-shock proteins | Q47897027 | ||
| Genealogy of the alpha-crystallin--small heat-shock protein superfamily | Q47897082 | ||
| Ischemia-induced phosphorylation and translocation of stress protein alpha B-crystallin to Z lines of myocardium. | Q48014059 | ||
| Phosphorylation of α-crystallin B in Alexander's disease brain | Q48612224 | ||
| Myofibrillar myopathy caused by novel dominant negative alpha B-crystallin mutations. | Q51638205 | ||
| Phosphorylation of alphaB-crystallin in mitotic cells and identification of enzymatic activities responsible for phosphorylation. | Q52183272 | ||
| Phosphorylation of alphaB-crystallin in response to various types of stress. | Q52191790 | ||
| Conversion from oligomers to tetramers enhances autophosphorylation by lens alpha A-crystallin. Specificity between alpha A- and alpha B-crystallin subunits. | Q52207133 | ||
| Alpha B crystallin and HSP28 are enhanced in the cerebral cortex of patients with Alzheimer's disease. | Q53208119 | ||
| P433 | issue | 21 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 4127-4137 | |
| P577 | publication date | 2015-07-26 | |
| P1433 | published in | Cellular and Molecular Life Sciences | Q5058352 |
| P1476 | title | Regulation of αA- and αB-crystallins via phosphorylation in cellular homeostasis | |
| P478 | volume | 72 |
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| Q47377350 | Loss of αB-crystallin function in zebrafish reveals critical roles in the development of the lens and stress resistance of the heart |
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