Preparation and properties of mitochondria derived from synaptosomes

scientific article published on February 15, 1976

Preparation and properties of mitochondria derived from synaptosomes is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1042/BJ1540423
P8608Fatcat IDrelease_zyz3ein5lrhj7gopecko52vs24
P953full work available at URLhttps://europepmc.org/articles/PMC1172723
https://europepmc.org/articles/PMC1172723?pdf=render
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/938457/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/938457/pdf/?tool=EBI
P3181OpenCitations bibliographic resource ID1488559
P932PMC publication ID1172723
P698PubMed publication ID938457
P5875ResearchGate publication ID22215421

P2093author name stringJ. B. Clark
J. C. Lai
P2860cites workProtein measurement with the Folin phenol reagentQ20900776
The isolation of nerve endings from brain: an electron-microscopic study of cell fragments derived by homogenization and centrifugationQ24531188
The separation of synaptic vesicles from nerve-ending particles (‘synaptosomes’)Q24532177
A new and rapid colorimetric determination of acetylcholinesterase activityQ26778487
Synaptic macromolecules: identification and metabolismQ39871166
The metabolic significance of anion transport in mitochondriaQ39950982
Ultrastructure and cytochemistry of the synaptic region. The macromolecular components involved in nerve transmission are being studiedQ40045657
CONTROL OF GLUTAMATE OXIDATION IN BRAIN AND LIVER MITOCHONDRIAL SYSTEMS.Q42063757
The morphology of fractions of rat forebrain synaptosomes separated on continuous sucrose density gradientsQ42172391
Differential effects of 2-oxo acids on pyruvate utilization and fatty acid synthesis in rat brainQ42581168
Metabolism of rat brain mitochondria. Studies on the potassium ion-stimulated oxidation of pyruvateQ42922362
Effect of phenylpyruvate on enzymes involved in fatty acid synthesis in rat brainQ42923903
LACTATE DEHYDROGENASE AS A CYTOPLASMIC MARKER IN BRAIN.Q42958374
Heterogeneity of mitochondria in rat brainQ48877615
The metabolism of rat brain mitochondria. Preparation and characterization.Q48894863
Respiration in vitro of synaptosomes from mammalian cerebral cortexQ49032262
The heterogeneity of rat brain mitochondria isolated on continuous sucrose gradientsQ49069577
Synaptic plasma membranes from rat brain synaptosomes: isolation and partial characterization.Q51115508
Isolation of plasma membranes from rat brain.Q51121131
Subcellular Distribution of Pyruvate Carboxylase, Diphosphopyridine Nucleotide and Triphosphopyridine Nucleotide Isocitrate Dehydrogenases, and Malate Enzyme in Rat BrainQ51184078
Subcellular distribution of enzymes of glutamate metabolism in rat brainQ51228244
Intracellular localization of glutamate decarboxylase, gamma-aminobutyrate transaminase and some other enzymes in brain tissue.Q51250846
SUBCELLULAR DISTRIBUTION OF THE ENZYMES OF THE GLUTAMIC ACID, GLUTAMINE AND γ‐AMINOBUTYRIC ACID CYCLES IN RAT BRAIN*Q51252753
The respiratory chain and oxidative phosphorylationQ74001812
Spectrophotometric measurements of the enzymatic formation of fumaric and cis-aconitic acidsQ80647823
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectmitochondrionQ39572
P304page(s)423–432
P577publication date1976-02-15
P1433published inBiochemical JournalQ864221
P1476titlePreparation and properties of mitochondria derived from synaptosomes
P478volume154

Reverse relations

cites work (P2860)
Q69648692A critique on the preparation and enzymatic characterization of synaptic and nonsynaptic mitochondria from hippocampus
Q48477465A rapid method for the isolation of metabolically active mitochondria from rat neurons and astrocytes in primary culture
Q42128413A rapid method for the preparation of relatively pure metabolically competent synaptosomes from rat brain
Q48686857A redox reaction between MPP+ and MPDP+ to produce superoxide radicals does not impair mitochondrial function
Q34023873Acquisition of chemoresistance in gliomas is associated with increased mitochondrial coupling and decreased ROS production
Q49048314Activation of glutamate dehydrogenase by leucine and its nonmetabolizable analogue in rat brain synaptosomes
Q48869551Age-dependent changes in pyruvate uptake by nonsynaptic and synaptic mitochondria from rat brain
Q70804527Age-related quantitative changes in enzyme activities of rat brain
Q35707254Astrocyte mitochondrial mechanisms of ischemic brain injury and neuroprotection
Q45297145Biochemical abnormalities and excitotoxicity in Huntington's disease brain.
Q70878197Brain Regional Distribution of Glutamic Acid Decarboxylase, Choline Acetyltransferase, and Acetylcholinesterase in the Rat: Effects of Chronic Manganese Chloride Administration after Two Years
Q42222317Brain alpha-ketoglutarate dehydrogenase complex: kinetic properties, regional distribution, and effects of inhibitors
Q48111277Brain mitochondrial citrate synthase and glutamate dehydrogenase: differential inhibition by fatty acyl coenzyme A derivatives
Q37172043Brain mitochondrial lipid abnormalities in mice susceptible to spontaneous gliomas.
Q39463835Cerebral ammonia metabolism in normal and hyperammonemic rats
Q48532491Changes of malic enzyme activity in the developing rat brain are due to both the increase of mitochondrial protein content and the increase of specific activity
Q48318528Choline and ethanolamine phosphotransferase activities in glomerular particles isolated from bovine cerebellar cortex
Q42547007Comparative studies on glutamate metabolism in synpatic and non-synaptic rat brain mitochondria
Q37152829Complex I is rate-limiting for oxygen consumption in the nerve terminal
Q46230307Curcuminoids modulates oxidative damage and mitochondrial dysfunction in diabetic rat brain.
Q33726402Decylubiquinone increases mitochondrial function in synaptosomes
Q42104815Development of mitochondrial energy metabolism in rat brain
Q36210621Dietary Omega-3 Fatty Acids Do Not Change Resistance of Rat Brain or Liver Mitochondria to Ca(2+) and/or Prooxidants
Q37420410Differential contribution of the mitochondrial respiratory chain complexes to reactive oxygen species production by redox cycling agents implicated in parkinsonism
Q72422360Effect of Aging on the Metabolism of Pyruvate and 3-Hydroxybutyrate in Nonsynaptic and Synaptic Mitochondria from Rat Brain
Q48585835Effect of cortico-striate pathway lesion on the activities of enzymes involved in synthesis and metabolism of amino acid neurotransmitters in the striatum
Q48654653Effect of lesions of the olfactory bulb on the levels of amino acids and related enzymes in the olfactory cortex of the guinea pig.
Q45104003Effect of low-dose lead acetate exposure on the metabolism of nucleic acids and lipids in cerebellum and hippocampus of rat during postnatal development
Q52517961Effect of organophosphorus insecticides on the oxidative processes in rat brain synaptosomes.
Q48594853Effect of prolonged and intermittent hypoxia on some cerebral enzymatic activities related to energy transduction
Q40160385Effects of osmolar changes on isolated mitochondria of brain and liver
Q41900151Energy transduction in intact synaptosomes. Influence of plasma-membrane depolarization on the respiration and membrane potential of internal mitochondria determined in situ
Q49149434Energy-metabolizing enzymes in brain regions of adult and aging rats
Q48768864Estimation of the chloramphenicol and cycloheximide inhibition of protein synthesis in brain cholinergic synaptosomes
Q46797884Ethanol withdrawal provokes mitochondrial injury in an estrogen preventable manner
Q52498603Evidence for compartmentalization of glutamate in rat brain synaptosomes using the glutamate sensitivity of phosphate-activated glutaminase as a functional test
Q37055738Examination of the brain mitochondrial lipidome using shotgun lipidomics
Q42904581Glutamate metabolism and transport in rat brain mitochondria
Q48686991Glutamine oxidation by dissociated cells and homogenates of rat brain: kinetics and inhibitor studies
Q48165622Heterogeneity of monoamine oxidase activities in synaptic and non-synaptic mitochondria derived from three brain regions: some functional implications
Q73553508Improved recovery of highly enriched mitochondrial fractions from small brain tissue samples
Q70737103Incorporation of linoleic acid into membrane glycerophospholipids from rat brain submitted to ischemia and hypoxia
Q42132440Influence of neonatal hypothyroidism on the development of ketone-body-metabolizing enzymes in rat brain
Q48600983Influence of the conformational state on the isoelectric points of rat brain synaptosomes, mitochondria and mitoplasts
Q43815607Isolation and characterization of intact mitochondria from neonatal rat brain
Q48643555Isolation and characterization of tightly coupled mitochondria from neurons and astrocytes in primary culture.
Q41993741Isolation of mitochondria from the CNS.
Q34468755Lipid Composition in Synaptic and Nonsynaptic Mitochondria from Rat Brains and Effect of Aging
Q35013455Lipidomic analysis and electron transport chain activities in C57BL/6J mouse brain mitochondria
Q43942176Metabolic compartmentation in cortical synaptosomes: influence of glucose and preferential incorporation of endogenous glutamate into GABA.
Q48494691Metabolic disturbances of synaptosomes isolated from ischemic gerbil brain.
Q66995762Metabolic properties of nerve endings isolated from rat brain
Q80975523Metabolism of [U-13C]glutamine and [U-13C]glutamate in isolated rat brain mitochondria suggests functional phosphate-activated glutaminase activity in matrix
Q40574989Mitochondrial heterogeneity within and between different cell types
Q28293245Mitochondrial localization and function of a subset of 22q11 deletion syndrome candidate genes.
Q24300975Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
Q52029587N-Acetylcysteine delays age-associated memory impairment in mice: role in synaptic mitochondria.
Q64787845N-acetylcysteine elicited increase in complex I activity in synaptic mitochondria from aged mice: implications for treatment of Parkinson's disease
Q48087819N-acetylcysteine elicited increase in cytochrome c oxidase activity in mice synaptic mitochondria.
Q48658513N-acetylcysteine protects against age-related increase in oxidized proteins in mouse synaptic mitochondria
Q72858115NADPH-dependent melanin pigment formation from 5-hydroxyindolealkylamines by hepatic and cerebral microsomes
Q41097327Neurochemical changes in rats chronically treated with a high concentration of manganese chloride
Q39180955Neuroprotection against neuroblastoma cell death induced by depletion of mitochondrial glutathione
Q43951933Neurotoxicity of ammonia and fatty acids: differential inhibition of mitochondrial dehydrogenases by ammonia and fatty acyl coenzyme A derivatives
Q73901639Oxidative derangement in rat synaptosomes induced by hyperglycaemia: restorative effect of dehydroepiandrosterone treatment
Q44059814Platelet-activating factor induces permeability transition and cytochrome c release in isolated brain mitochondria
Q48297038Postmortem changes in the enzymes of GABA and glutamate metabolism in the cerebellum and forebrain of newborn and adult rats
Q36952616Preparation of purified perikaryal and synaptosomal mitochondrial fractions from relatively small hypothalamic brain samples
Q77952657Protection against UVB inactivation (in vitro) of rat lens enzymes by natural antioxidants
Q48089955Protein synthesis rates in rat brain regions and subcellular fractions during aging
Q35917814Proteomic analysis of mitochondrial proteins
Q28579068Purification and properties of succinyl-CoA:3-oxo-acid CoA-transferase from rat brain
Q67278419Pyruvate Dehydrogenase Phosphate (PDHb) Phosphatase in Brain: Activity, Properties, and Subcellular Localization
Q69256800Quantitation of the beta-bungarotoxin-induced release of lactate dehydrogenase from cerebrocortical synaptosomes
Q48854675Rat brain synaptosomes prepared by phase partition
Q48843453Rat cortex synaptic and nonsynaptic mitochondria: Enzymatic characterization and pharmacological effects of naftidrofuryl
Q49100190Reduced transcription of mitochondrial DNA in the senescent rat. Tissue dependence and effect of L-carnitine
Q48648481Regional development of glutamate dehydrogenase in the rat brain
Q41959089Regional enzyme development in rat brain. Enzymes of energy metabolism
Q48942468Regulation of glutaminase by exogenous glutamate, ammonia and 2-oxoglutarate in synaptosomal enriched preparation from rat brain
Q67007409Relationship between the 4-aminobutyrate bypath and the oxidation of 2-oxoglutarate in rat brain mitochondria
Q42461288Respiration in primary cultured cerebellar granule neurons and cerebral cortical neurons
Q50143077Role of Astrocytic Mitochondria in Limiting Ischemic Brain Injury?
Q48769775Saturation of the processing of newly synthesized rRNA in isolated brain mitochondria
Q33415997Silencing of PINK1 expression affects mitochondrial DNA and oxidative phosphorylation in dopaminergic cells
Q33985326Soluble, prefibrillar α-synuclein oligomers promote complex I-dependent, Ca2+-induced mitochondrial dysfunction.
Q72860054Specific binding of kainic acid to purified subcellular fractions from rat brain
Q48765883Structural and functional aspects of the respiratory chain of synaptic and nonsynaptic mitochondria derived from selected brain regions
Q40037467Studies on the control of 4-aminobutyrate metabolism in ‘synaptosomal’ and free rat brain mitochondria
Q41621281Studies on the pyruvate dehydrogenase complex in brain with the arylamine acetyltransferase-coupled assay
Q44090308Superoxide activates constitutive nitric oxide synthase in a brain particulate fraction
Q48530059Synaptic Mitochondria Sustain More Damage than Non-Synaptic Mitochondria after Traumatic Brain Injury and Are Protected by Cyclosporine A.
Q72847804Synaptosomal uptake: the modifying effect of mitochondria
Q30643822The Glutamate-Glutamine (GABA) Cycle: Importance of Late Postnatal Development and Potential Reciprocal Interactions between Biosynthesis and Degradation
Q48673801The activities of some energy-metabolising enzymes in nonsynaptic (free) and synaptic mitochondria derived from selected brain regions
Q48384069The antioxidant defences of brain mitochondria during short-term forebrain ischemia and recirculation in the rat.
Q28566566The distribution of glutamine synthetase in subcellular fractions of rat brain
Q48274826The effect of (-)hydroxycitrate on pyruvate metabolism in rat brain synaptosomes
Q41492702The heterogeneity of mitochondrial DNA in different tissues from the same animal
Q48866120The ontogeny of acetylcholinesterase activities in rat brain regions and the effect of chronic treatment with manganese chloride
Q41827657The regulation of glutamate metabolism by tricarboxylic acid-cycle activity in rat brain mitochondria
Q42235214The relationship between nerve terminal adenosine triphosphatases and neurotransmitter release: as determined by the use of antidepressant and other CNS-active drugs
Q42848752The role of ADP in the modulation of the calcium-efflux pathway in rat brain mitochondria
Q49046895The role of chloride in acetylcholine metabolism
Q48348729The subcellular localization of glutamate dehydrogenase (GDH): is GDH a marker for mitochondria in brain?
Q39205181The synthesis of glutamate by rat brain mitochondria
Q41810424Thyroid hormone treatment alters phospholipid composition and membrane fluidity of rat brain mitochondria
Q28328284Toxic action of 2′-chloro-2,4-dinitro-5′, 6-di(trifluoromethyl) diphenylamine in the rat
Q58750407Trajectories of Brain Lactate and Re-visited Oxygen-Glucose Index Calculations Do Not Support Elevated Non-oxidative Metabolism of Glucose Across Childhood
Q49126989Type A and type B monoamine oxidase activities in rat brain and liver mitochondria: A comparison of their properties using the non-ionic detergent triton X-100
Q74275814UVB irradiation alters the activities and kinetic properties of the enzymes of energy metabolism in rat lens during aging