scholarly article | Q13442814 |
P356 | DOI | 10.1074/JBC.M109771200 |
P698 | PubMed publication ID | 11781314 |
P50 | author | Jan-Åke Gustafsson | Q5777769 |
Stine M. Ulven | Q65017045 | ||
P2093 | author name string | Hilde Irene Nebb | |
Kari Anne Risan Tobin | |||
Gertrud U. Schuster | |||
Hilde Hermansen Steineger | |||
Sissel Mahle Andresen | |||
P2860 | cites work | Role of LXRs in control of lipogenesis | Q24290548 |
Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway | Q24316367 | ||
LXR, a nuclear receptor that defines a distinct retinoid response pathway | Q24317347 | ||
NER, a new member of the gene family encoding the human steroid hormone nuclear receptor | Q24322700 | ||
Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter | Q24550969 | ||
Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells | Q24561820 | ||
Ubiquitous receptor: a receptor that modulates gene activation by retinoic acid and thyroid hormone receptors | Q24562732 | ||
OR-1, a member of the nuclear receptor superfamily that interacts with the 9-cis-retinoic acid receptor | Q24563731 | ||
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta | Q24598068 | ||
A novel orphan receptor specific for a subset of thyroid hormone-responsive elements and its interaction with the retinoid/thyroid hormone receptor subfamily | Q24609094 | ||
Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient mice | Q24681140 | ||
Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease | Q26778460 | ||
A unified nomenclature system for the nuclear receptor superfamily | Q28142509 | ||
Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcriptional role for specific oxysterols | Q28143718 | ||
A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis | Q28199913 | ||
SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene | Q28264180 | ||
Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha | Q28273937 | ||
ADD1/SREBP-1c is required in the activation of hepatic lipogenic gene expression by glucose | Q28583495 | ||
Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes | Q28646399 | ||
Nuclear receptor regulation of cholesterol and bile acid metabolism. | Q33796274 | ||
Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes | Q33878155 | ||
Sterol upregulation of human CETP expression in vitro and in transgenic mice by an LXR element | Q33939047 | ||
Sterol regulatory element-binding proteins (SREBPs): key regulators of nutritional homeostasis and insulin action | Q33996668 | ||
The role of orphan nuclear receptors in the regulation of cholesterol homeostasis | Q34059740 | ||
Insulin-regulated gene expression | Q34332489 | ||
Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1. | Q34451430 | ||
Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR. | Q35926317 | ||
Differential effects of constitutively active phosphatidylinositol 3-kinase on glucose transport, glycogen synthase activity, and DNA synthesis in 3T3-L1 adipocytes | Q36564714 | ||
Nutritional regulation of the fatty acid synthase promoter in vivo: sterol regulatory element binding protein functions through an upstream region containing a sterol regulatory element | Q37254332 | ||
Dual DNA binding specificity of ADD1/SREBP1 controlled by a single amino acid in the basic helix-loop-helix domain | Q38295909 | ||
High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study | Q41115222 | ||
Unique requirements for retinoid-dependent transcriptional activation by the orphan receptor LXR. | Q41130960 | ||
The peroxisome proliferator-activated receptor alpha is a phosphoprotein: regulation by insulin | Q41164662 | ||
Induction of the three peroxisomal beta-oxidation enzymes is synergistically regulated by dexamethasone and fatty acids, and counteracted by insulin in Morris 7800C1 hepatoma cells in culture | Q42453426 | ||
Regulation of the transcriptional activity of the peroxisome proliferator-activated receptor alpha by phosphorylation of a ligand-independent trans-activating domain | Q42470071 | ||
Overexpression of a constitutively active form of phosphatidylinositol 3-kinase is sufficient to promote Glut 4 translocation in adipocytes | Q42523326 | ||
Upstream stimulatory factor binding to the E-box at -65 is required for insulin regulation of the fatty acid synthase promoter | Q42835179 | ||
Insulin effects on sterol regulatory-element-binding protein-1c (SREBP-1c) transcriptional activity in rat hepatocytes. | Q42997321 | ||
Structural characterisation of the mouse nuclear oxysterol receptor genes LXRalpha and LXRbeta | Q47884555 | ||
Cross-talk between fatty acid and cholesterol metabolism mediated by liver X receptor-alpha. | Q51556346 | ||
Dexamethasone and insulin demonstrate marked and opposite regulation of the steady-state mRNA level of the peroxisomal proliferator-activated receptor (PPAR) in hepatic cells. Hormonal modulation of fatty-acid-induced transcription. | Q51592966 | ||
P433 | issue | 12 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | fatty acid | Q61476 |
preproinsulin | Q7240673 | ||
P304 | page(s) | 10691–10697 | |
P577 | publication date | 2002-03-22 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis | |
P478 | volume | 277 |
Q24677042 | Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue |
Q50772546 | Can the liver X receptor work its magic in skeletal muscle too? |
Q35607325 | Cholesterol synthesis is associated with hepatic lipid content and dependent on fructose/glucose intake in healthy humans |
Q37196514 | Current role of fenofibrate in the prevention and management of non-alcoholic fatty liver disease |
Q90294832 | Dairy Foods and Dairy Fats: New Perspectives on Pathways Implicated in Cardiometabolic Health |
Q34626518 | Deciphering the nuclear bile acid receptor FXR paradigm |
Q36744605 | Deubiquitylase Inhibition Reveals Liver X Receptor-independent Transcriptional Regulation of the E3 Ubiquitin Ligase IDOL and Lipoprotein Uptake |
Q51380135 | Dexamethasone-induced hepatic lipogenesis is insulin dependent in chickens (Gallus gallus domesticus). |
Q34132499 | Different regulation of the LXRalpha promoter activity by isoforms of CCAAT/enhancer-binding proteins |
Q28583521 | Down-regulation of hepatic and intestinal Abcg5 and Abcg8 expression associated with altered sterol fluxes in rats with streptozotocin-induced diabetes |
Q35313420 | Early growth response 1 (Egr1) regulates cholesterol biosynthetic gene expression |
Q39604605 | Effect of dietary fat on hepatic liver X receptor expression in P-glycoprotein deficient mice: implications for cholesterol metabolism. |
Q34955169 | Effects of adiposity on plasma lipid response to reductions in dietary saturated fatty acids and cholesterol |
Q53627487 | Effects of inhibiting PI3K-Akt-mTOR pathway on lipid metabolism homeostasis in goose primary hepatocytes. |
Q26996783 | Energy metabolism in the liver |
Q24806573 | Establishment of a monoclonal antibody for human LXRalpha: Detection of LXRalpha protein expression in human macrophages |
Q42447473 | Expression of the insulin-responsive glucose transporter GLUT4 in adipocytes is dependent on liver X receptor alpha |
Q33636261 | Fasting-induced FGF21 is repressed by LXR activation via recruitment of an HDAC3 corepressor complex in mice |
Q39881165 | Fibroblast growth factor-19, a novel factor that inhibits hepatic fatty acid synthesis |
Q43053495 | Hepatic glucose sensing: does flux matter? |
Q34609585 | Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis |
Q38009669 | Hepatic steatosis in type 1 diabetes |
Q24606762 | Human SREBP1c expression in liver is directly regulated by peroxisome proliferator-activated receptor alpha (PPARalpha) |
Q42466977 | Identification of a novel rat hepatic gene induced early by insulin, independently of glucose. |
Q91889154 | Identification of an intrinsic lysophosphatidic acid acyltransferase activity in the lipolytic inhibitor G0/G1 switch gene 2 (G0S2) |
Q46562134 | Increased de novo lipogenesis and delayed conversion of large VLDL into intermediate density lipoprotein particles contribute to hyperlipidemia in glycogen storage disease type 1a. |
Q39879951 | Induction of SREBP-1c mRNA by differentiation and LXR ligand in human keratinocytes |
Q42053294 | Insulin activates the rat sterol-regulatory-element-binding protein 1c (SREBP-1c) promoter through the combinatorial actions of SREBP, LXR, Sp-1 and NF-Y cis-acting elements |
Q87882628 | Insulin regulates lipid and glucose metabolism similarly in two lines of rainbow trout divergently selected for muscle fat content |
Q35049218 | Insulin regulation of cholesterol 7alpha-hydroxylase expression in human hepatocytes: roles of forkhead box O1 and sterol regulatory element-binding protein 1c. |
Q44681147 | Insulin resistance is associated with increased cholesterol synthesis and decreased cholesterol absorption in normoglycemic men. |
Q37785391 | Insulin signaling in fatty acid and fat synthesis: a transcriptional perspective |
Q38758630 | Insulin-Mediated Downregulation of Apolipoprotein A-I Gene in Human Hepatoma Cell Line HepG2: The Role of Interaction Between FOXO1 and LXRβ Transcription Factors. |
Q40659499 | Jatropha curcas Protein Concentrate Stimulates Insulin Signaling, Lipogenesis, Protein Synthesis and the PKCα Pathway in Rat Liver |
Q45982093 | LXRalpha activation perturbs hepatic insulin signaling and stimulates production of apolipoprotein B-containing lipoproteins. |
Q34428893 | LXRβ is required for glucocorticoid-induced hyperglycemia and hepatosteatosis in mice. |
Q35754362 | Lipoprotein kinetics in the metabolic syndrome: pathophysiological and therapeutic lessons from stable isotope studies |
Q38905346 | Liver X receptor regulates hepatic nuclear O-GlcNAc signaling and carbohydrate responsive element-binding protein activity |
Q39380086 | Liver X receptor α is involved in the transcriptional regulation of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene |
Q37646873 | Liver X receptor α mediates hepatic triglyceride accumulation through upregulation of G0/G1 Switch Gene 2 expression |
Q35084303 | Liver X receptors and the control of cholesterol homeostasis: potential therapeutic targets for the treatment of atherosclerosis |
Q37119273 | Liver X receptors as therapeutic targets in metabolism and atherosclerosis |
Q57065028 | MiR-205 Mediated Cu-Induced Lipid Accumulation in Yellow Catfish |
Q36859379 | Munc18c in adipose tissue is downregulated in obesity and is associated with insulin |
Q33761680 | NPC1L1 inhibitor ezetimibe is a reliable therapeutic agent for non-obese patients with nonalcoholic fatty liver disease |
Q34682304 | New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: a role for the transcription factor sterol regulatory element binding protein-1c |
Q39771613 | Nuclear receptor liver X receptor is O-GlcNAc-modified in response to glucose |
Q48370446 | Peroxisome proliferator-activated receptor alpha deficiency abolishes the response of lipogenic gene expression to re-feeding: restoration of the normal response by activation of liver X receptor alpha. |
Q46327164 | Pharmacological activation of LXR in utero directly influences ABC transporter expression and function in mice but does not affect adult cholesterol metabolism |
Q37393336 | Regulation of hepatic fatty acid elongase and desaturase expression in diabetes and obesity |
Q35559701 | Reviews: current topicsrole of nuclear receptors in the regulation of gene expression by dietary fatty acids (review) |
Q36918305 | Role of ChREBP in hepatic steatosis and insulin resistance. |
Q44253526 | Selective proteolytic processing of rat hepatic sterol regulatory element binding protein-1 (SREBP-1) and SREBP-2 during postnatal development |
Q36485655 | Signalling mechanisms linking hepatic glucose and lipid metabolism |
Q36981140 | Supra-molecular association and polymorphic behaviour in systems containing bile acid salts |
Q44552199 | The LXR ligand T0901317 induces severe lipogenesis in the db/db diabetic mouse |
Q40524290 | The liver X receptor ligand T0901317 down-regulates APOA5 gene expression through activation of SREBP-1c |
Q44922801 | The mechanism mediating the activation of acetyl-coenzyme A carboxylase-alpha gene transcription by the liver X receptor agonist T0-901317. |
Q34768157 | The role of FoxO in the regulation of metabolism. |
Q44548838 | The role of liver X receptor-alpha in the fatty acid regulation of hepatic gene expression |
Q33672543 | Transcriptional control of hepatic lipid metabolism by SREBP and ChREBP. |
Q36683297 | Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR. |
Q26778594 | Transcriptional regulation of hepatic lipogenesis |
Q64355579 | Visceral Obesity is Associated with High Levels of Serum Squalene* |
Q51544818 | Visceral fat positively correlates with cholesterol synthesis in dyslipidaemic patients. |
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