Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis

scientific journal article

Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M109771200
P698PubMed publication ID11781314

P50authorJan-Åke GustafssonQ5777769
Stine M. UlvenQ65017045
P2093author name stringHilde Irene Nebb
Kari Anne Risan Tobin
Gertrud U. Schuster
Hilde Hermansen Steineger
Sissel Mahle Andresen
P2860cites workRole of LXRs in control of lipogenesisQ24290548
Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathwayQ24316367
LXR, a nuclear receptor that defines a distinct retinoid response pathwayQ24317347
NER, a new member of the gene family encoding the human steroid hormone nuclear receptorQ24322700
Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoterQ24550969
Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cellsQ24561820
Ubiquitous receptor: a receptor that modulates gene activation by retinoic acid and thyroid hormone receptorsQ24562732
OR-1, a member of the nuclear receptor superfamily that interacts with the 9-cis-retinoic acid receptorQ24563731
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbetaQ24598068
A novel orphan receptor specific for a subset of thyroid hormone-responsive elements and its interaction with the retinoid/thyroid hormone receptor subfamilyQ24609094
Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient miceQ24681140
Isolation of biologically active ribonucleic acid from sources enriched in ribonucleaseQ26778460
A unified nomenclature system for the nuclear receptor superfamilyQ28142509
Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcriptional role for specific oxysterolsQ28143718
A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesisQ28199913
SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor geneQ28264180
Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alphaQ28273937
ADD1/SREBP-1c is required in the activation of hepatic lipogenic gene expression by glucoseQ28583495
Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genesQ28646399
Nuclear receptor regulation of cholesterol and bile acid metabolism.Q33796274
Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genesQ33878155
Sterol upregulation of human CETP expression in vitro and in transgenic mice by an LXR elementQ33939047
Sterol regulatory element-binding proteins (SREBPs): key regulators of nutritional homeostasis and insulin actionQ33996668
The role of orphan nuclear receptors in the regulation of cholesterol homeostasisQ34059740
Insulin-regulated gene expressionQ34332489
Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1.Q34451430
Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR.Q35926317
Differential effects of constitutively active phosphatidylinositol 3-kinase on glucose transport, glycogen synthase activity, and DNA synthesis in 3T3-L1 adipocytesQ36564714
Nutritional regulation of the fatty acid synthase promoter in vivo: sterol regulatory element binding protein functions through an upstream region containing a sterol regulatory elementQ37254332
Dual DNA binding specificity of ADD1/SREBP1 controlled by a single amino acid in the basic helix-loop-helix domainQ38295909
High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural studyQ41115222
Unique requirements for retinoid-dependent transcriptional activation by the orphan receptor LXR.Q41130960
The peroxisome proliferator-activated receptor alpha is a phosphoprotein: regulation by insulinQ41164662
Induction of the three peroxisomal beta-oxidation enzymes is synergistically regulated by dexamethasone and fatty acids, and counteracted by insulin in Morris 7800C1 hepatoma cells in cultureQ42453426
Regulation of the transcriptional activity of the peroxisome proliferator-activated receptor alpha by phosphorylation of a ligand-independent trans-activating domainQ42470071
Overexpression of a constitutively active form of phosphatidylinositol 3-kinase is sufficient to promote Glut 4 translocation in adipocytesQ42523326
Upstream stimulatory factor binding to the E-box at -65 is required for insulin regulation of the fatty acid synthase promoterQ42835179
Insulin effects on sterol regulatory-element-binding protein-1c (SREBP-1c) transcriptional activity in rat hepatocytes.Q42997321
Structural characterisation of the mouse nuclear oxysterol receptor genes LXRalpha and LXRbetaQ47884555
Cross-talk between fatty acid and cholesterol metabolism mediated by liver X receptor-alpha.Q51556346
Dexamethasone and insulin demonstrate marked and opposite regulation of the steady-state mRNA level of the peroxisomal proliferator-activated receptor (PPAR) in hepatic cells. Hormonal modulation of fatty-acid-induced transcription.Q51592966
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectfatty acidQ61476
preproinsulinQ7240673
P304page(s)10691–10697
P577publication date2002-03-22
P1433published inJournal of Biological ChemistryQ867727
P1476titleLiver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis
P478volume277

Reverse relations

cites work (P2860)
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