| scholarly article | Q13442814 |
| P50 | author | Pierre Maechler | Q58471331 |
| Susanne Mandrup | Q37841265 | ||
| P2093 | author name string | Francesca Frigerio | |
| Tina Nielsen | |||
| Kim Ravnskjaer | |||
| Michael Boergesen | |||
| P2860 | cites work | Glucose Sensitivity and Metabolism-Secretion Coupling Studied during Two-Year Continuous Culture in INS-1E Insulinoma Cells | Q42798453 |
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| Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy | Q45099786 | ||
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| Recombinant human PPAR-beta/delta ligand-binding domain is locked in an activated conformation by endogenous fatty acids. | Q46889021 | ||
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| Glucose-induced repression of PPAR gene expression in pancreatic -cells involves PP2A activation and AMPK inactivation | Q58166687 | ||
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| A system for stable expression of short interfering RNAs in mammalian cells | Q27860875 | ||
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| Lipotoxicity of the pancreatic beta-cell is associated with glucose-dependent esterification of fatty acids into neutral lipids | Q28361455 | ||
| The PPARs: from orphan receptors to drug discovery | Q28371618 | ||
| Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta | Q28379553 | ||
| Dehydroepiandrosterone sulfate and beta-cell function: enhanced glucose-induced insulin secretion and altered gene expression in rodent pancreatic beta-cells | Q28580382 | ||
| Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome | Q28592809 | ||
| Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity | Q29619156 | ||
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| Research resource: nuclear hormone receptor expression in the endocrine pancreas | Q30438376 | ||
| Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia | Q30794086 | ||
| PPARdelta is a very low-density lipoprotein sensor in macrophages | Q34330290 | ||
| Palmitate inhibits insulin gene expression by altering PDX-1 nuclear localization and reducing MafA expression in isolated rat islets of Langerhans | Q34338020 | ||
| Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells | Q34478047 | ||
| The antiepileptic drug topiramate preserves metabolism-secretion coupling in insulin secreting cells chronically exposed to the fatty acid oleate. | Q34560736 | ||
| Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships | Q35883220 | ||
| Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes | Q35923385 | ||
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| Fatty acid signaling in the beta-cell and insulin secretion | Q36666157 | ||
| The insulinotropic potency of fatty acids is influenced profoundly by their chain length and degree of saturation | Q37370093 | ||
| Peroxisome proliferator-activated receptor subtype- and cell-type-specific activation of genomic target genes upon adenoviral transgene delivery | Q38407726 | ||
| Peroxisome proliferator-activated receptor alpha (PPARalpha) potentiates, whereas PPARgamma attenuates, glucose-stimulated insulin secretion in pancreatic beta-cells | Q40425673 | ||
| Mitochondrial functional state in clonal pancreatic beta-cells exposed to free fatty acids | Q40663264 | ||
| A unique PPARgamma ligand with potent insulin-sensitizing yet weak adipogenic activity | Q40771890 | ||
| Long-term exposure of beta-INS cells to high glucose concentrations increases anaplerosis, lipogenesis, and lipogenic gene expression | Q41029405 | ||
| Over-expression of sterol-regulatory-element-binding protein-1c (SREBP1c) in rat pancreatic islets induces lipogenesis and decreases glucose-stimulated insulin release: modulation by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR). | Q42156889 | ||
| Peroxisome proliferator-activated receptor alpha (PPARalpha) protects against oleate-induced INS-1E beta cell dysfunction by preserving carbohydrate metabolism | Q42462866 | ||
| Enhanced mitochondrial metabolism may account for the adaptation to insulin resistance in islets from C57BL/6J mice fed a high-fat diet | Q42503904 | ||
| Troglitazone lowers islet fat and restores beta cell function of Zucker diabetic fatty rats | Q42545275 | ||
| Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay | Q42549325 | ||
| P433 | issue | 6 | |
| P921 | main subject | mitochondrion | Q39572 |
| fatty acid | Q61476 | ||
| preproinsulin | Q7240673 | ||
| P304 | page(s) | 1370–1379 | |
| P577 | publication date | 2010-06-01 | |
| P1433 | published in | Journal of Lipid Research | Q6295449 |
| P1476 | title | PPARdelta is a fatty acid sensor that enhances mitochondrial oxidation in insulin-secreting cells and protects against fatty acid-induced dysfunction | |
| P478 | volume | 51 |
| Q64055391 | Activation of PPARs Modulates Signalling Pathways and Expression of Regulatory Genes in Osteoclasts Derived from Human CD14+ Monocytes |
| Q39371041 | Activation of PPARδ up-regulates the expression of insulin gene transcription factor MafA and ameliorates glucose-induced insulin secretion impaired by palmitate |
| Q47103455 | Antihyperglycemic Effect of Rosa Damascena is Mediated by PPAR.γ Gene Expression in Animal Model of Insulin Resistance |
| Q38895012 | Beta cell response to nutrient overload involves phospholipid remodelling and lipid peroxidation |
| Q89748572 | CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors |
| Q34787111 | ChREBP mediates glucose repression of peroxisome proliferator-activated receptor alpha expression in pancreatic beta-cells |
| Q37410528 | Desnutrin/ATGL activates PPARδ to promote mitochondrial function for insulin secretion in islet β cells |
| Q42763240 | Effects of canola and high-oleic-acid canola oils on abdominal fat mass in individuals with central obesity. |
| Q90722135 | Exploration and Development of PPAR Modulators in Health and Disease: An Update of Clinical Evidence |
| Q54386070 | Impaired exercise-induced mitochondrial biogenesis in the obese Zucker rat, despite PGC-1α induction, is due to compromised mitochondrial translation elongation. |
| Q46162360 | In vivo imaging reveals selective PPAR activity in the skin of peroxisome proliferator-activated receptor responsive element-luciferase reporter mice |
| Q34482135 | Involvement of dynamin-related protein 1 in free fatty acid-induced INS-1-derived cell apoptosis |
| Q36127114 | Lipolytic products activate peroxisome proliferator-activated receptor (PPAR) α and δ in brown adipocytes to match fatty acid oxidation with supply |
| Q36088639 | Major Alterations of Phosphatidylcholine and Lysophosphotidylcholine Lipids in the Substantia Nigra Using an Early Stage Model of Parkinson's Disease |
| Q38951163 | Mechanisms of β-cell functional adaptation to changes in workload |
| Q39793833 | Monte Carlo cross-validation analysis screens pathway cross-talk associated with Parkinson's disease |
| Q36237199 | Novel identification of the free fatty acid receptor FFAR1 that promotes contraction in airway smooth muscle. |
| Q35816903 | Nurr1 and Retinoid X Receptor Ligands Stimulate Ret Signaling in Dopamine Neurons and Can Alleviate α-Synuclein Disrupted Gene Expression |
| Q38810152 | Nutrigenomic regulation of adipose tissue development - role of retinoic acid: A review |
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| Q36072327 | PPARδ Activation Rescues Pancreatic β-Cell Line INS-1E from Palmitate-Induced Endoplasmic Reticulum Stress through Enhanced Fatty Acid Oxidation |
| Q36293315 | Peroxisome proliferator-activated receptorβ/δ activation is essential for modulating p-Foxo1/Foxo1 status in functional insulin-positive cell differentiation |
| Q41015855 | Prolactin and oleic acid synergistically stimulate β-cell proliferation and growth in rat islets. |
| Q36134154 | Protective Role of PPARdelta in Lipoapoptosis of Pancreatic β Cells |
| Q38092186 | Reactive aldehydes--second messengers of free radicals in diabetes mellitus |
| Q35404923 | Role of lipid peroxidation and PPAR-δ in amplifying glucose-stimulated insulin secretion |
| Q37163006 | SCD1 activity in muscle increases triglyceride PUFA content, exercise capacity, and PPARδ expression in mice |
| Q91761076 | The PPARδ Agonist GW501516 Improves Lipolytic/Lipogenic Balance through CPT1 and PEPCK during the Development of Pre-Implantation Bovine Embryos |
| Q58114531 | The Role of PPAR-δ in Metabolism, Inflammation, and Cancer: Many Characters of a Critical Transcription Factor |
| Q98465853 | The interplay between non-esterified fatty acids and bovine peroxisome proliferator-activated receptors: results of an in vitro hybrid approach |
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