| scholarly article | Q13442814 |
| P356 | DOI | 10.1210/EN.2003-1099 |
| P953 | full work available at URL | http://academic.oup.com/endo/article-pdf/145/2/667/9021727/endo0667.pdf |
| https://academic.oup.com/endo/article-pdf/145/2/667/9021727/endo0667.pdf | ||
| P698 | PubMed publication ID | 14592952 |
| P5875 | ResearchGate publication ID | 9030583 |
| P50 | author | Pierre Maechler | Q58471331 |
| P2093 | author name string | Claes B. Wollheim | |
| Blanca Rubi | |||
| Arnaud Merglen | |||
| Sten Theander | |||
| Gaelle Chaffard | |||
| P2860 | cites work | Regulation of immunoreactive-insulin release from a rat cell line (RINm5F) | Q42446795 |
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| Voltage-independent calcium channels mediate slow oscillations of cytosolic calcium that are glucose dependent in pancreatic beta-cells | Q42532834 | ||
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| Islet beta-cell secretion determines glucagon release from neighbouring alpha-cells. | Q44364388 | ||
| A 48-hour exposure of pancreatic islets to calpain inhibitors impairs mitochondrial fuel metabolism and the exocytosis of insulin | Q44449208 | ||
| Ca(2+)-induced Ca(2+) release in the pancreatic beta-cell: direct evidence of endoplasmic reticulum Ca(2+) release | Q44514615 | ||
| Low access resistance perforated patch recordings using amphotericin B. | Q46990168 | ||
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| Autofluorescence-activated cell sorting of pancreatic islet cells: Purification of insulin-containing B-cells according to glucose-induced changes in cellular redox state | Q53868795 | ||
| Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis. | Q53920238 | ||
| Voltage-activated Na+ currents and their suppression by phorbol ester in clonal insulin-producing RINm5F cells | Q60032721 | ||
| A new in vitro model for the study of pancreatic A and B cells | Q69866352 | ||
| Quantitative subcellular imaging of glucose metabolism within intact pancreatic islets | Q71081856 | ||
| Insulinotropic action of glutamic acid dimethyl ester | Q72762109 | ||
| Junctional communication of pancreatic beta cells contributes to the control of insulin secretion and glucose tolerance | Q24629609 | ||
| Triggering and amplifying pathways of regulation of insulin secretion by glucose | Q27863677 | ||
| Molecular mechanisms and regulation of insulin exocytosis as a paradigm of endocrine secretion | Q27876210 | ||
| Mitochondrial calcium transport: physiological and pathological relevance | Q28247285 | ||
| NADH shuttle system regulates K(ATP) channel-dependent pathway and steps distal to cytosolic Ca(2+) concentration elevation in glucose-induced insulin secretion | Q28371866 | ||
| Role of NADH shuttles in glucose-induced insulin secretion from fetal beta-cells | Q28575099 | ||
| Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines | Q29619317 | ||
| Contributions of mitochondria to animal physiology: from homeostatic sensor to calcium signalling and cell death | Q33538979 | ||
| Mitochondrial activation directly triggers the exocytosis of insulin in permeabilized pancreatic beta-cells. | Q33886922 | ||
| Modulation of the bursting properties of single mouse pancreatic beta-cells by artificial conductances | Q34169965 | ||
| Banting Lecture 1995. A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm | Q34370210 | ||
| Mitochondria as the conductor of metabolic signals for insulin exocytosis in pancreatic beta-cells. | Q35046362 | ||
| Evidence that glucose can control insulin release independently from its action on ATP-sensitive K+ channels in mouse B cells | Q35601028 | ||
| Separation of the glucose-stimulated cytoplasmic and mitochondrial NAD(P)H responses in pancreatic islet beta cells | Q36966837 | ||
| Glucose-stimulated insulin secretion correlates with changes in mitochondrial and cytosolic Ca2+ in aequorin-expressing INS-1 cells | Q37361803 | ||
| Continuous monitoring of ATP levels in living insulin secreting cells expressing cytosolic firefly luciferase | Q38553145 | ||
| Amplification of exocytosis by Ca2+-induced Ca2+ release in INS-1 pancreatic beta cells | Q40679793 | ||
| Mitochondrial metabolism sets the maximal limit of fuel-stimulated insulin secretion in a model pancreatic beta cell: a survey of four fuel secretagogues | Q40753443 | ||
| Insulin secretion and differential gene expression in glucose-responsive and -unresponsive MIN6 sublines | Q40853034 | ||
| Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion | Q40871524 | ||
| Pancreatic beta-cell-to-beta-cell interactions are required for integrated responses to nutrient stimuli: enhanced Ca2+ and insulin secretory responses of MIN6 pseudoislets. | Q40944883 | ||
| Engineering cultured insulin-secreting pancreatic B-cell lines | Q40975804 | ||
| Molecular characterization of the glucose-sensing mechanism in the clonal insulin-secreting BRIN-BD11 cell line | Q41068898 | ||
| Rapid changes of mitochondrial Ca2+ revealed by specifically targeted recombinant aequorin | Q41112236 | ||
| Effects of glucose, forskolin and tolbutamide on membrane potential and insulin secretion in the insulin-secreting cell line INS-1. | Q41180604 | ||
| Clonal insulinoma cell line that stably maintains correct glucose responsiveness. | Q41418434 | ||
| The pancreatic beta-cell as a fuel sensor: an electrophysiologist's viewpoint | Q41482117 | ||
| Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets | Q41516250 | ||
| Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms | Q41729392 | ||
| P4510 | describes a project that uses | INS-1E | Q54897749 |
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | endocrinology | Q162606 |
| glucose | Q37525 | ||
| insulinoma | Q1501239 | ||
| cell line | Q21014462 | ||
| P1104 | number of pages | 12 | |
| P304 | page(s) | 667-678 | |
| P577 | publication date | 2003-10-30 | |
| P1433 | published in | Endocrinology | Q3054009 |
| P1476 | title | Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells | |
| Glucose Sensitivity and Metabolism-Secretion Coupling Studied during Two-Year Continuous Culture in INS-1E Insulinoma Cells | |||
| P478 | volume | 145 |
| Q50243540 | A Phytochrome Sensory Domain Permits Receptor Activation by Red Light |
| Q37393515 | A Presenilin/Notch1 pathway regulated by miR-375, miR-30a, and miR-34a mediates glucotoxicity induced-pancreatic beta cell apoptosis |
| Q42776894 | A TRPV1-to-secretagogin regulatory axis controls pancreatic β-cell survival by modulating protein turnover. |
| Q39721171 | A low-risk ZnT-8 allele (W325) for post-transplantation diabetes mellitus is protective against cyclosporin A-induced impairment of insulin secretion |
| Q47950643 | A multidisciplinary guided practical on type I diabetes engaging students in inquiry-based learning |
| Q39051827 | A possible role of transglutaminase 2 in the nucleus of INS-1E and of cells of human pancreatic islets |
| Q49566480 | A subclass of serum anti-ZnT8 antibodies directed to the surface of live pancreatic β-cells |
| Q33631445 | A20 Inhibits β-Cell Apoptosis by Multiple Mechanisms and Predicts Residual β-Cell Function in Type 1 Diabetes |
| Q38765352 | Aberrant Accumulation of the Diabetes Autoantigen GAD65 in Golgi Membranes in Conditions of ER Stress and Autoimmunity |
| Q33925263 | Abnormal glucose homeostasis and pancreatic islet function in mice with inactivation of the Fem1b gene |
| Q40369965 | Activation of KATP channels by H2S in rat insulin-secreting cells and the underlying mechanisms |
| Q39101026 | Activation of TRPV4 channel in pancreatic INS-1E beta cells enhances glucose-stimulated insulin secretion via calcium-dependent mechanisms. |
| Q37594080 | Activation of angiotensin type 2 receptors partially ameliorates streptozotocin-induced diabetes in male rats by islet protection |
| Q35747758 | Activation of the unfolded protein response pathway causes ceramide accumulation in yeast and INS-1E insulinoma cells |
| Q46559653 | Adrenaline-induced hyperpolarization of mouse pancreatic islet cells is mediated by G protein-gated inwardly rectifying potassium (GIRK) channels |
| Q30845005 | Advances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation. |
| Q28484498 | Allosteric modulation of the activity of the glucagon-like peptide-1 (GLP-1) metabolite GLP-1 9-36 amide at the GLP-1 receptor |
| Q28577962 | Altered MENIN expression disrupts the MAFA differentiation pathway in insulinoma |
| Q40054894 | An ancestral retroviral protein identified as a therapeutic target in type-1 diabetes |
| Q38914454 | Androgen receptor silences thioredoxin-interacting protein and competitively inhibits glucocorticoid receptor-mediated apoptosis in pancreatic β-Cells |
| Q37341974 | Angiotensin type 2 receptor in pancreatic islets of adult rats: a novel insulinotropic mediator |
| Q64895988 | Anthocyanins from purple corn activate free fatty acid-receptor 1 and glucokinase enhancing in vitro insulin secretion and hepatic glucose uptake. |
| Q35441776 | Anti-incretin, Anti-proliferative Action of Dopamine on β-Cells |
| Q28387870 | Association of dioxin and other persistent organic pollutants (POPs) with diabetes: epidemiological evidence and new mechanisms of beta cell dysfunction |
| Q39284913 | Autophagy plays a protective role in endoplasmic reticulum stress-mediated pancreatic β cell death |
| Q39988234 | Beta cell chromogranin B is partially segregated in distinct granules and can be released separately from insulin in response to stimulation. |
| Q38895012 | Beta cell response to nutrient overload involves phospholipid remodelling and lipid peroxidation |
| Q37668822 | Bisphenol A Is More Potent than Phthalate Metabolites in Reducing Pancreatic β-Cell Function |
| Q37289307 | CB1 cannabinoid receptors couple to focal adhesion kinase to control insulin release |
| Q37311421 | CO2/HCO3(-)- and calcium-regulated soluble adenylyl cyclase as a physiological ATP sensor |
| Q28391541 | Can exposure to environmental chemicals increase the risk of diabetes type 1 development? |
| Q37416435 | Cav1.2 and Cav1.3 are differentially coupled to glucagon-like peptide-1 potentiation of glucose-stimulated insulin secretion in the pancreatic beta-cell line INS-1. |
| Q47178676 | Cell Separation in Aqueous Two-Phase Systems - Influence of Polymer Molecular Weight and Tie-Line Length on the Resolution of Five Model Cell Lines |
| Q37969558 | Cell swelling-induced peptide hormone secretion |
| Q40368133 | Cell type-specific activation of metabolism reveals that beta-cell secretion suppresses glucagon release from alpha-cells in rat pancreatic islets |
| Q34787111 | ChREBP mediates glucose repression of peroxisome proliferator-activated receptor alpha expression in pancreatic beta-cells |
| Q35070214 | Changes in mitochondrial carriers exhibit stress-specific signatures in INS-1Eβ-cells exposed to glucose versus fatty acids |
| Q47428737 | Characterization of the Molecular Mechanisms Underlying Glucose Stimulated Insulin Secretion from Isolated Pancreatic β-cells Using Post-translational Modification Specific Proteomics (PTMomics). |
| Q28909807 | Characterization of the sodium/hydrogen exchanger NHA2 |
| Q35783450 | Chemical inhibition of fatty acid absorption and cellular uptake limits lipotoxic cell death |
| Q34307812 | Comparative Analysis of the Mitochondrial Physiology of Pancreatic β Cells |
| Q93205455 | Contribution of Oxidative Stress and Impaired Biogenesis of Pancreatic β-Cells to Type 2 Diabetes |
| Q35995073 | Controlled aggregation of primary human pancreatic islet cells leads to glucose-responsive pseudoislets comparable to native islets |
| Q42504848 | Coupling of Insulin Secretion and Display of a Granule-resident Zinc Transporter ZnT8 on the Surface of Pancreatic Beta Cells |
| Q102144637 | Coxsackievirus B Type 4 Infection in β Cells Downregulates the Chaperone Prefoldin URI to Induce a MODY4-like Diabetes via Pdx1 Silencing |
| Q28575583 | Defective mitophagy driven by dysregulation of rheb and KIF5B contributes to mitochondrial reactive oxygen species (ROS)-induced nod-like receptor 3 (NLRP3) dependent proinflammatory response and aggravates lipotoxicity |
| Q33636568 | Degradation of an intramitochondrial protein by the cytosolic proteasome |
| Q37163495 | Degradation of cAMP-responsive element-binding protein by the ubiquitin-proteasome pathway contributes to glucotoxicity in beta-cells and human pancreatic islets |
| Q27322836 | Development of a Rapid Insulin Assay by Homogenous Time-Resolved Fluorescence |
| Q35206511 | Di(2-ethylhexyl) phthalate-induced apoptosis in rat INS-1 cells is dependent on activation of endoplasmic reticulum stress and suppression of antioxidant protection |
| Q40273572 | Diabetes-associated mitochondrial DNA mutation A3243G impairs cellular metabolic pathways necessary for beta cell function. |
| Q46668094 | Different signaling pathways involved in glucose- and cell swelling-induced insulin secretion by rat pancreatic islets in vitro. |
| Q42698931 | Differentiation of Mouse Embryonic Stem Cells toward Functional Pancreatic β-Cell Surrogates through Epigenetic Regulation of Pdx1 by Nitric Oxide |
| Q41836119 | Discovery of 2-Pyridylpyrimidines as the First Orally Bioavailable GPR39 Agonists |
| Q37270490 | Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase. |
| Q47566338 | Distinguishing signal from autofluorescence in cryogenic correlated light and electron microscopy of mammalian cells. |
| Q91286708 | Dopamine D2 receptor modulates Wnt expression and control of cell proliferation |
| Q46675901 | Dopamine D2-like receptors are expressed in pancreatic beta cells and mediate inhibition of insulin secretion |
| Q28574719 | Dynamic regulation of uncoupling protein 2 content in INS-1E insulinoma cells |
| Q46845391 | Dynamics of intracellular oxygen in PC12 Cells upon stimulation of neurotransmission. |
| Q48524359 | Dysfunctional autophagy following exposure to pro-inflammatory cytokines contributes to pancreatic β-cell apoptosis |
| Q40125416 | Effect of iNOS and NF-kappaB gene silencing on beta-cell survival and function |
| Q38808885 | Effect of insulin analogues on phosphatidyl inositol-3 kinase/Akt signalling in INS-1 rat pancreatic derived β-cells |
| Q39380440 | Effect of the AMP-kinase modulators AICAR, metformin and compound C on insulin secretion of INS-1E rat insulinoma cells under standard cell culture conditions. |
| Q35087366 | Effects of zinc supplementation and zinc chelation on in vitro β-cell function in INS-1E cells. |
| Q58581291 | Efficient Synthesis and in Silico Studies of the Benzimidazole Hybrid Scaffold with the Quinolinyloxadiazole Skeleton with Potential α-Glucosidase Inhibitory, Anticoagulant, and Antiplatelet Activities for Type-II Diabetes Mellitus Management and Tr |
| Q38725314 | Encapsulation of Insulin-Secreting Cells Expressing a Genetically Encoded Fluorescent Calcium Indicator for Cell-Based Sensing In Vivo |
| Q88258482 | Epigenetic regulation in the tumorigenesis of MEN1-associated endocrine cell types |
| Q90470418 | Essential role of glucokinase in the protection of pancreatic β cells to the glucose energetic status |
| Q34653026 | Evaluation of the INS-1 832/13 cell line as a beta-cell based screening system to assess pollutant effects on beta-cell function |
| Q39382550 | Exendin-4 increases the expression of hypoxia-inducible factor-1α in rat islets and preserves the endocrine cell volume of both free and macroencapsulated islet grafts |
| Q89819706 | Exploring G Protein-Coupled Receptor Signaling in Primary Pancreatic Islets |
| Q34614958 | Expression of recipient CD47 on rat insulinoma cell xenografts prevents macrophage-mediated rejection through SIRPα inhibitory signaling in mice |
| Q37213905 | FAD synthesis and degradation in the nucleus create a local flavin cofactor pool |
| Q36108434 | Fatty acid transport protein-2 inhibitor Grassofermata/CB5 protects cells against lipid accumulation and toxicity |
| Q39961462 | Fatty acids do not activate UCP2 in pancreatic beta cells: comparison with UCP1. |
| Q50016678 | Feeder-cell-independent culture of the pig embryonic stem cell-derived exocrine pancreatic cell line, PICM-31. |
| Q64902326 | Fibroblast Growth Factor 21 Stimulates Pancreatic Islet Autophagy via Inhibition of AMPK-mTOR Signaling. |
| Q39864309 | Fluorescence microscopy studies on islet amyloid polypeptide fibrillation at heterogeneous and cellular membrane interfaces and its inhibition by resveratrol. |
| Q87841459 | Frequency and consequence of the recurrent YY1 p.T372R mutation in sporadic insulinomas |
| Q34944028 | Functional mapping of disease susceptibility loci using cell biology |
| Q43646347 | Functional significance of repressor element 1 silencing transcription factor (REST) target genes in pancreatic beta cells. |
| Q40323043 | Gamma-aminobutyric acid up- and downregulates insulin secretion from beta cells in concert with changes in glucose concentration |
| Q51330636 | Gastric bypass surgery may improve beta cell apoptosis with ghrelin overexpression in patients with BMI ≥ 32.5 kg/m(2.). |
| Q34285082 | Gene networks modified by sulphonylureas in beta cells: a pathway-based analysis of insulin secretion and cell death |
| Q43873373 | Genetic and biochemical evidence for a functional role of BACE1 in the regulation of insulin mRNA expression |
| Q38844959 | Ghrelin's Effects on Proinflammatory Cytokine Mediated Apoptosis and Their Impact on β-Cell Functionality. |
| Q36843192 | Glucose and GLP-1 stimulate cAMP production via distinct adenylyl cyclases in INS-1E insulinoma cells |
| Q28576688 | Glucose metabolism-related protein 1 (GMRP1) regulates pancreatic beta cell proliferation and apoptosis via activation of Akt signalling pathway in rats and mice |
| Q27329439 | Glucose stimulation induces dynamic change of mitochondrial morphology to promote insulin secretion in the insulinoma cell line INS-1E |
| Q64271838 | Growing Trans-Species Islets in Tumor Extract-Remodeled Testicles |
| Q34976995 | H2O2-induced Ca2+ influx and its inhibition by N-(p-amylcinnamoyl) anthranilic acid in the beta-cells: involvement of TRPM2 channels |
| Q33413749 | HNF4alpha and HNF1alpha dysfunction as a molecular rational for cyclosporine induced posttransplantation diabetes mellitus |
| Q26795437 | Hands-on experiments on glycemia regulation and type 1 diabetes |
| Q42770460 | Haploid insufficiency of suppressor enhancer Lin12 1-like (SEL1L) protein predisposes mice to high fat diet-induced hyperglycemia. |
| Q34232244 | Haploinsufficiency of Dmxl2, encoding a synaptic protein, causes infertility associated with a loss of GnRH neurons in mouse |
| Q35213294 | Hepatic nuclear factor 1alpha (HNF1alpha) dysfunction down-regulates X-box-binding protein 1 (XBP1) and sensitizes beta-cells to endoplasmic reticulum stress |
| Q88881600 | Homogeneous Time-resolved Förster Resonance Energy Transfer-based Assay for Detection of Insulin Secretion |
| Q99579311 | Human embryonic stem cells as an in vitro model for studying developmental origins of type 2 diabetes |
| Q35217022 | Huntingtin-interacting protein 14 is a type 1 diabetes candidate protein regulating insulin secretion and beta-cell apoptosis |
| Q38880892 | H₂O₂-Activated Mitochondrial Phospholipase iPLA₂γ Prevents Lipotoxic Oxidative Stress in Synergy with UCP2, Amplifies Signaling via G-Protein-Coupled Receptor GPR40, and Regulates Insulin Secretion in Pancreatic β-Cells |
| Q34468268 | ICER induced by hyperglycemia represses the expression of genes essential for insulin exocytosis |
| Q40036683 | ICER-1gamma overexpression drives palmitate-mediated connexin36 down-regulation in insulin-secreting cells. |
| Q35187794 | Identification of a small molecule activator of novel PKCs for promoting glucose-dependent insulin secretion |
| Q42515066 | Identification of the molecular dysfunction caused by glutamate dehydrogenase S445L mutation responsible for hyperinsulinism/hyperammonemia |
| Q55261240 | Improved Labeling of Pancreatic Islets Using Cationic Magnetoliposomes. |
| Q47179983 | Inactivation of SPAK kinase reduces body weight gain in mice fed a High-fat diet by improving energy expenditure and insulin sensitivity |
| Q40203702 | Increasing uncoupling protein-2 in pancreatic beta cells does not alter glucose-induced insulin secretion but decreases production of reactive oxygen species. |
| Q36930761 | Inhibition of DYRK1A Stimulates Human β-Cell Proliferation |
| Q40180167 | Inhibition of GSK3 promotes replication and survival of pancreatic beta cells |
| Q36093203 | Inhibition of SCD1 impairs palmitate-derived autophagy at the step of autophagosome-lysosome fusion in pancreatic β-cells |
| Q42819671 | Inhibition of SH2-domain containing inositol phosphatase 2 (SHIP2) in insulin producing INS1E cells improves insulin signal transduction and induces proliferation |
| Q39326566 | Inhibition of histone deacetylase 3 protects beta cells from cytokine-induced apoptosis |
| Q33740671 | Inhibition of the Mitochondrial Glutamate Carrier SLC25A22 in Astrocytes Leads to Intracellular Glutamate Accumulation |
| Q40605055 | Insulin secretion profiles are modified by overexpression of glutamate dehydrogenase in pancreatic islets. |
| Q39406909 | Insulin-secreting INS-1E cells express functional TRPV1 channels |
| Q33750755 | Involvement of microRNAs in the cytotoxic effects exerted by proinflammatory cytokines on pancreatic beta-cells. |
| Q39429839 | Involvement of the RNA-binding protein ARE/poly(U)-binding factor 1 (AUF1) in the cytotoxic effects of proinflammatory cytokines on pancreatic beta cells |
| Q28828592 | Kinase-Independent Small-Molecule Inhibition of JAK-STAT Signaling |
| Q35027842 | Label-free detection of insulin and glucagon within human islets of Langerhans using Raman spectroscopy |
| Q37288088 | Long-term exposure to genistein improves insulin secretory function of pancreatic beta-cells |
| Q34903445 | Macromolecular crowding as a suppressor of human IAPP fibril formation and cytotoxicity |
| Q36073863 | Measurement of the Absolute Magnitude and Time Courses of Mitochondrial Membrane Potential in Primary and Clonal Pancreatic Beta-Cells |
| Q39854680 | Measuring mitochondrial bioenergetics in INS-1E insulinoma cells |
| Q28573533 | Melatonin-mediated insulin synthesis during endoplasmic reticulum stress involves HuD expression in rat insulinoma INS-1E cells |
| Q26777794 | Membrane Potential and Calcium Dynamics in Beta Cells from Mouse Pancreas Tissue Slices: Theory, Experimentation, and Analysis |
| Q89051430 | Metabolic activation-driven mitochondrial hyperpolarization predicts insulin secretion in human pancreatic beta-cells |
| Q64387419 | Metabolic signatures suggest o-phosphocholine to UDP-N-acetylglucosamine ratio as a potential biomarker for high-glucose and/or palmitate exposure in pancreatic β-cells |
| Q39485974 | Methylglyoxal impairs insulin signalling and insulin action on glucose-induced insulin secretion in the pancreatic beta cell line INS-1E. |
| Q40140488 | MicroRNA-124a regulates Foxa2 expression and intracellular signaling in pancreatic beta-cell lines |
| Q37594551 | Microfabrication of homogenous, asymmetric cell-laden hydrogel capsules. |
| Q37050350 | Minireview: Dopaminergic regulation of insulin secretion from the pancreatic islet |
| Q40482479 | Mitochondrial activation and the pyruvate paradox in a human cell line. |
| Q37375716 | Mitochondrial glutamate carrier GC1 as a newly identified player in the control of glucose-stimulated insulin secretion |
| Q42763181 | Mitochondrial uncoupling protein-2 is not involved in palmitate-induced impairment of glucose-stimulated insulin secretion in INS-1E insulinoma cells and is not needed for the amplification of insulin release. |
| Q57587073 | Modulation of human IAPP fibrillation: cosolutes, crowders and chaperones |
| Q50084245 | Molecular genetics of the transcription factor GLIS3 identifies its dual function in beta cells and neurons |
| Q33498114 | Molecular mechanisms of tungstate-induced pancreatic plasticity: a transcriptomics approach. |
| Q42177561 | Multimodal imaging of pancreatic beta cells in vivo by targeting transmembrane protein 27 (TMEM27). |
| Q33391087 | Mutations in UCP2 in congenital hyperinsulinism reveal a role for regulation of insulin secretion |
| Q28578639 | Neurexin-1α contributes to insulin-containing secretory granule docking |
| Q33900669 | Neuronal calcium sensor-1 potentiates glucose-dependent exocytosis in pancreatic beta cells through activation of phosphatidylinositol 4-kinase beta. |
| Q90970792 | New roles for dopamine D2 and D3 receptors in pancreatic beta cell insulin secretion |
| Q35878674 | No non-redundant function of suppressor of cytokine signaling 2 in insulin producing β-cells |
| Q39085330 | Novel insights into pancreatic β-cell glucolipotoxicity from real-time functional analysis of mitochondrial energy metabolism in INS-1E insulinoma cells |
| Q33231962 | Oscillations of cyclic AMP in hormone-stimulated insulin-secreting beta-cells |
| Q89474868 | Overexpression of native IF1 downregulates glucose-stimulated insulin secretion by pancreatic INS-1E cells |
| Q39864393 | Overexpression of the malate-aspartate NADH shuttle member Aralar1 in the clonal beta-cell line BRIN-BD11 enhances amino-acid-stimulated insulin secretion and cell metabolism. |
| Q33577434 | PDX1 deficiency causes mitochondrial dysfunction and defective insulin secretion through TFAM suppression |
| Q34663501 | PED/PEA-15 inhibits hydrogen peroxide-induced apoptosis in Ins-1E pancreatic beta-cells via PLD-1 |
| Q28574319 | PPARdelta is a fatty acid sensor that enhances mitochondrial oxidation in insulin-secreting cells and protects against fatty acid-induced dysfunction |
| Q42415411 | PTPMT1 Inhibition Lowers Glucose through Succinate Dehydrogenase Phosphorylation |
| Q28483101 | Palmitate activates autophagy in INS-1E β-cells and in isolated rat and human pancreatic islets |
| Q53217400 | Pancreatic Beta Cell Survival and Signaling Pathways: Effects of Type 1 Diabetes-Associated Genetic Variants. |
| Q53821054 | Pancreatic β cells overexpressing hIAPP impaired mitophagy and unbalanced mitochondrial dynamics. |
| Q42462866 | Peroxisome proliferator-activated receptor alpha (PPARalpha) protects against oleate-induced INS-1E beta cell dysfunction by preserving carbohydrate metabolism |
| Q89050027 | Phytonutrient genistein is a survival factor for pancreatic β-cells via GPR30-mediated mechanism |
| Q30513973 | Plasma membrane potential oscillations in insulin secreting Ins-1 832/13 cells do not require glycolysis and are not initiated by fluctuations in mitochondrial bioenergetics |
| Q36669997 | Polyphenol-Rich Extract of Syzygium cumini Leaf Dually Improves Peripheral Insulin Sensitivity and Pancreatic Islet Function in Monosodium L-Glutamate-Induced Obese Rats. |
| Q93090059 | Potential of Mitochondria-Targeted Antioxidants to Prevent Oxidative Stress in Pancreatic β-cells |
| Q55514460 | Pro-inflammatory cytokines attenuate glucose-stimulated insulin secretion from INS-1E insulinoma cells by restricting mitochondrial pyruvate oxidation capacity - Novel mechanistic insight from real-time analysis of oxidative phosphorylation. |
| Q64951763 | Prolonged Exposure to Insulin Inactivates Akt and Erk1/2 and Increases Pancreatic Islet and INS1E β-Cell Apoptosis. |
| Q55248558 | Proteasomal degradation of the histone acetyl transferase p300 contributes to beta-cell injury in a diabetes environment. |
| Q35123951 | Proteasome dysfunction mediates high glucose-induced apoptosis in rodent beta cells and human islets |
| Q33267158 | Protein profiling of pancreatic islets |
| Q37320446 | Proteins altered by elevated levels of palmitate or glucose implicated in impaired glucose-stimulated insulin secretion |
| Q40070947 | Proteomics analysis of cytokine-induced dysfunction and death in insulin-producing INS-1E cells: new insights into the pathways involved. |
| Q40167745 | Proteomics analysis of insulin secretory granules. |
| Q83864655 | Quantitative measurement of mitochondrial membrane potential in cultured cells: calcium-induced de- and hyperpolarization of neuronal mitochondria |
| Q36519817 | REST represses a subset of the pancreatic endocrine differentiation program. |
| Q37268198 | Receptor for advanced glycation endproducts signaling cascades are activated in pancreatic fibroblasts, but not in the INS1E insulinoma cell line: Are mesenchymal cells major players in chronic inflammation? |
| Q27021930 | Redox homeostasis in pancreatic β cells |
| Q41885627 | Redox properties of ginger extracts: Perspectives of use of Zingiber officinale Rosc. as antidiabetic agent |
| Q27317203 | Reduction of connexin36 content by ICER-1 contributes to insulin-secreting cells apoptosis induced by oxidized LDL particles |
| Q28577539 | Reexpression of oncoprotein MafB in proliferative β-cells and Men1 insulinomas in mouse |
| Q30486711 | Regulation of insulin granule turnover in pancreatic beta-cells by cleaved ICA512. |
| Q24338198 | Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase |
| Q33551074 | Relative roles of the different Pax6 domains for pancreatic alpha cell development |
| Q35182244 | Resveratrol ameliorates the maturation process of β-cell-like cells obtained from an optimized differentiation protocol of human embryonic stem cells |
| Q57476675 | Resveratrol long-term treatment differentiates INS-1E beta-cell towards improved glucose response and insulin secretion |
| Q34675695 | Resveratrol potentiates glucose-stimulated insulin secretion in INS-1E beta-cells and human islets through a SIRT1-dependent mechanism. |
| Q91745425 | Ribosome-associated vesicles: A dynamic subcompartment of the endoplasmic reticulum in secretory cells |
| Q37109991 | Role of MAPK in apolipoprotein CIII-induced apoptosis in INS-1E cells |
| Q35404923 | Role of lipid peroxidation and PPAR-δ in amplifying glucose-stimulated insulin secretion |
| Q38321332 | SOX6 attenuates glucose-stimulated insulin secretion by repressing PDX1 transcriptional activity and is down-regulated in hyperinsulinemic obese mice. |
| Q55460789 | Secretagogin protects Pdx1 from proteasomal degradation to control a transcriptional program required for β cell specification. |
| Q39797821 | Silencing of the mitochondrial NADH shuttle component aspartate-glutamate carrier AGC1/Aralar1 in INS-1E cells and rat islets. |
| Q41711182 | Single Fluorescent Protein-Based Indicators for Zinc Ion (Zn(2+)). |
| Q28576077 | Small molecule glucokinase activators disturb lipid homeostasis and induce fatty liver in rodents: a warning for therapeutic applications in humans |
| Q36846424 | Small molecule kaempferol modulates PDX-1 protein expression and subsequently promotes pancreatic β-cell survival and function via CREB. |
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| Q38943061 | The Pancreatic β-Cell: A Bioenergetic Perspective |
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| Q54897749 | INS-1E | described by source | P1343 |
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