| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2012PLoSO...736188M |
| P356 | DOI | 10.1371/JOURNAL.PONE.0036188 |
| P8608 | Fatcat ID | release_6cd3j4olcne6vpps5fx4srgjku |
| P3181 | OpenCitations bibliographic resource ID | 2006099 |
| P932 | PMC publication ID | 3341371 |
| P698 | PubMed publication ID | 22563482 |
| P5875 | ResearchGate publication ID | 224915963 |
| P50 | author | Lorella Marselli | Q50965652 |
| Marco Bugliani | Q79304855 | ||
| Piero Marchetti | Q37382607 | ||
| P2093 | author name string | Michela Novelli | |
| Pellegrino Masiello | |||
| Matilde Masini | |||
| Pascale Beffy | |||
| Vincenzo De Tata | |||
| Luisa Martino | |||
| P2860 | cites work | Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes | Q23757358 |
| LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing | Q24597817 | ||
| Autophagy in the Pathogenesis of Disease | Q27860558 | ||
| Autophagy fights disease through cellular self-digestion | Q27860902 | ||
| Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae | Q27935838 | ||
| Autophagy regulates lipid metabolism | Q29547421 | ||
| The role of autophagy during the early neonatal starvation period | Q29547489 | ||
| Development by self-digestion: molecular mechanisms and biological functions of autophagy | Q29547880 | ||
| Autophagy is activated for cell survival after endoplasmic reticulum stress | Q29614485 | ||
| Autophagic cell death: the story of a misnomer | Q29614564 | ||
| Type 2 diabetes-a matter of beta-cell life and death? | Q53873519 | ||
| Chronic perifusion of rat islets with palmitate suppresses glucose-stimulated insulin release | Q72801419 | ||
| Regulated autophagy controls hormone content in secretory-deficient pancreatic endocrine beta-cells | Q80500402 | ||
| Enhanced signaling downstream of ribonucleic Acid-activated protein kinase-like endoplasmic reticulum kinase potentiates lipotoxic endoplasmic reticulum stress in human islets. | Q39751051 | ||
| 3-Methyladenine suppresses cell migration and invasion of HT1080 fibrosarcoma cells through inhibiting phosphoinositide 3-kinases independently of autophagy inhibition. | Q40111245 | ||
| Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2. | Q40179972 | ||
| Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival. | Q40202994 | ||
| Chronic palmitate but not oleate exposure induces endoplasmic reticulum stress, which may contribute to INS-1 pancreatic beta-cell apoptosis | Q40294776 | ||
| Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle | Q40334538 | ||
| Lipases in lysosomes, what for? | Q40380003 | ||
| Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress | Q40527936 | ||
| Insulin-secreting cell lines: classification, characteristics and potential applications. | Q41026494 | ||
| Autophagy: a sweet process in diabetes | Q42442804 | ||
| Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia | Q42442810 | ||
| Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet | Q42442818 | ||
| Autophagy and apoptosis: what is the connection? | Q42571763 | ||
| Glucose Sensitivity and Metabolism-Secretion Coupling Studied during Two-Year Continuous Culture in INS-1E Insulinoma Cells | Q42798453 | ||
| Free fatty acids stimulate autophagy in pancreatic β-cells via JNK pathway. | Q42871332 | ||
| Metabolic and functional studies on isolated islets in a new rat model of type 2 diabetes | Q43590315 | ||
| Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated. | Q43972538 | ||
| Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death | Q44559324 | ||
| Utilizing flow cytometry to monitor autophagy in living mammalian cells | Q44821204 | ||
| Autophagy in human type 2 diabetes pancreatic beta cells. | Q46050859 | ||
| Life and death partners: apoptosis, autophagy and the cross-talk between them | Q46072576 | ||
| Effects of palmitate on ER and cytosolic Ca2+ homeostasis in beta-cells | Q46164585 | ||
| Protective role of autophagy in palmitate-induced INS-1 beta-cell death. | Q46388763 | ||
| ER-phagy: selective autophagy of the endoplasmic reticulum. | Q46683304 | ||
| Mitochondrial dynamics--fusion, fission, movement, and mitophagy--in neurodegenerative diseases | Q29615646 | ||
| Autophagy and metabolism | Q29615974 | ||
| Autophagy in cell death: an innocent convict? | Q29617604 | ||
| The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients. | Q33300966 | ||
| Palmitate-induced beta-cell dysfunction is associated with excessive NO production and is reversed by thiazolidinedione-mediated inhibition of GPR40 transduction mechanisms | Q33334424 | ||
| Towards better understanding of the contributions of overwork and glucotoxicity to the beta-cell inadequacy of type 2 diabetes | Q33509610 | ||
| Mitochondrial dysfunction and oxidative stress mediate the physiological impairment induced by the disruption of autophagy | Q33588721 | ||
| Intracellular quality control by autophagy: how does autophagy prevent neurodegeneration? | Q33998075 | ||
| Altered lipid content inhibits autophagic vesicular fusion | Q34017069 | ||
| Autophagy: cellular and molecular mechanisms | Q34103624 | ||
| Another way to die: autophagic programmed cell death | Q34462605 | ||
| Ubiquitinated-protein aggregates form in pancreatic beta-cells during diabetes-induced oxidative stress and are regulated by autophagy | Q34613854 | ||
| Islet beta cell failure in type 2 diabetes | Q34698810 | ||
| Fatty acids suppress autophagic turnover in β-cells | Q35604849 | ||
| The isolated pancreatic islet as a micro-organ and its transplantation to cure diabetes: celebrating the legacy of Paul Lacy | Q35878665 | ||
| Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes | Q35923385 | ||
| Autophagy: a cell repair mechanism that retards ageing and age-associated diseases and can be intensified pharmacologically | Q36594284 | ||
| Nutrient control of macroautophagy in mammalian cells. | Q36603388 | ||
| Cell death modalities: classification and pathophysiological implications | Q36790543 | ||
| Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium. | Q36870862 | ||
| Initiation and execution of lipotoxic ER stress in pancreatic beta-cells | Q36910693 | ||
| Functions of autophagy in hepatic and pancreatic physiology and disease | Q36948885 | ||
| An overview of pancreatic beta-cell defects in human type 2 diabetes: implications for treatment. | Q36949127 | ||
| The role for endoplasmic reticulum stress in diabetes mellitus | Q37019672 | ||
| Autophagy: a lysosomal degradation pathway with a central role in health and disease | Q37245031 | ||
| The sensitivity of pancreatic beta-cells to mitochondrial injuries triggered by lipotoxicity and oxidative stress. | Q37269525 | ||
| Emerging roles for the ubiquitin-proteasome system and autophagy in pancreatic beta-cells | Q37277467 | ||
| Autophagy: principles and significance in health and disease | Q37330775 | ||
| Potential role of autophagy in modulation of lipid metabolism | Q37627028 | ||
| Autophagic pathways and metabolic stress | Q37804447 | ||
| Causes and cures for endoplasmic reticulum stress in lipotoxic β-cell dysfunction | Q37804459 | ||
| Autophagy in the cellular energetic balance | Q37870537 | ||
| Improved insulin sensitivity by rapamycin is associated with reduction of mTOR and S6K1 activities in L6 myotubes | Q39405602 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | autophagy | Q288322 |
| P304 | page(s) | e36188 | |
| P577 | publication date | 2012-05-01 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | Palmitate activates autophagy in INS-1E β-cells and in isolated rat and human pancreatic islets | |
| P478 | volume | 7 |
| Q34127184 | Age-related impairment of pancreatic Beta-cell function: pathophysiological and cellular mechanisms |
| Q28387870 | Association of dioxin and other persistent organic pollutants (POPs) with diabetes: epidemiological evidence and new mechanisms of beta cell dysfunction |
| Q49687928 | Autophagy Dysregulation and Obesity-Associated Pathologies. |
| Q38214981 | Autophagy and cancer metabolism |
| Q58699659 | Autophagy in Metabolic Age-Related Human Diseases |
| Q38209287 | Autophagy in adipose tissue and the beta cell: implications for obesity and diabetes |
| Q33712340 | Autophagy protects against palmitate-induced apoptosis in hepatocytes |
| Q89099863 | Autophagy protects bone marrow mesenchymal stem cells from palmitate‑induced apoptosis through the ROS‑JNK/p38 MAPK signaling pathways |
| Q38336391 | Autophagy regulates insulin resistance following endoplasmic reticulum stress in diabetes |
| Q39103618 | Cathepsin B contributes to autophagy-related 7 (Atg7)-induced nod-like receptor 3 (NLRP3)-dependent proinflammatory response and aggravates lipotoxicity in rat insulinoma cell line |
| Q36406366 | Co-localization of acinar markers and insulin in pancreatic cells of subjects with type 2 diabetes |
| Q43188408 | Correction: palmitate activates autophagy in INS-1E β-cells and in isolated rat and human pancreatic islets |
| Q36284095 | Delayed apoptosis allows islet β-cells to implement an autophagic mechanism to promote cell survival |
| Q47219594 | Development of fluorescence imaging probes for nicotinic acetylcholine α4β2∗ receptors |
| Q48524359 | Dysfunctional autophagy following exposure to pro-inflammatory cytokines contributes to pancreatic β-cell apoptosis |
| Q96172470 | Emerging roles of ATG proteins and membrane lipids in autophagosome formation |
| Q28655456 | Emerging targets in lipid-based therapy |
| Q28066377 | Erythropoietin and mTOR: A "One-Two Punch" for Aging-Related Disorders Accompanied by Enhanced Life Expectancy |
| Q64911734 | Fatty Acid-Stimulated Insulin Secretion vs. Lipotoxicity. |
| Q64902326 | Fibroblast Growth Factor 21 Stimulates Pancreatic Islet Autophagy via Inhibition of AMPK-mTOR Signaling. |
| Q26800615 | FoxO Transcription Factors and Regenerative Pathways in Diabetes Mellitus |
| Q41917444 | High-fat diet increases autophagic flux in pancreatic beta cells in vivo and ex vivo in mice |
| Q36093203 | Inhibition of SCD1 impairs palmitate-derived autophagy at the step of autophagosome-lysosome fusion in pancreatic β-cells |
| Q38875279 | Insulin-like Growth Factor 2 Overexpression Induces β-Cell Dysfunction and Increases Beta-cell Susceptibility to Damage |
| Q64230296 | Lipotoxicity and Cell Maintenance in Obesity and Type 2 Diabetes |
| Q26866054 | Lipotoxicity in the pancreatic beta cell: not just survival and function, but proliferation as well? |
| Q47328893 | Lycium barbarum polysaccharide arbitrates palmitate-induced apoptosis in MC3T3‑E1 cells through decreasing the activation of ERS‑mediated apoptosis pathway |
| Q92186029 | Lysosomal degradation of newly formed insulin granules contributes to β cell failure in diabetes |
| Q53378728 | Mast cells infiltrate pancreatic islets in human type 1 diabetes. |
| Q37392815 | Mechanisms of palmitate-induced cell death in human osteoblasts |
| Q38336639 | Minireview: Autophagy in pancreatic β-cells and its implication in diabetes |
| Q41063199 | Mitigating Ischemic Injury of Stem Cell-Derived Insulin-Producing Cells after Transplant |
| Q37643238 | MitoNEET-Parkin Effects in Pancreatic α- and β-Cells, Cellular Survival, and Intrainsular Cross Talk |
| Q92603438 | Mitochondrial Ca2+ Uptake Relieves Palmitate-Induced Cytosolic Ca2+ Overload in MIN6 Cells |
| Q64100369 | Modulation of Autophagy Influences the Function and Survival of Human Pancreatic Beta Cells Under Endoplasmic Reticulum Stress Conditions and in Type 2 Diabetes |
| Q28080679 | New Insights for Oxidative Stress and Diabetes Mellitus |
| Q36487424 | Novel directions for diabetes mellitus drug discovery |
| Q26749047 | Novel nervous and multi-system regenerative therapeutic strategies for diabetes mellitus with mTOR |
| Q36432388 | Oxidant stress and signal transduction in the nervous system with the PI 3-K, Akt, and mTOR cascade |
| Q52316229 | Pancreatic Beta Cell Death: Novel Potential Mechanisms in Diabetes Therapy. |
| Q41867019 | Pharmacological correction of obesity-induced autophagy arrest using calcium channel blockers |
| Q38367977 | Programming apoptosis and autophagy with novel approaches for diabetes mellitus |
| Q35919336 | Protection of Human Pancreatic Islets from Lipotoxicity by Modulation of the Translocon |
| Q35140269 | Research resource: Monitoring endoplasmic reticulum membrane integrity in β-cells at the single-cell level. |
| Q37532658 | Role of CYB5A in pancreatic cancer prognosis and autophagy modulation |
| Q65001183 | Sonodynamic therapy inhibits palmitate-induced beta cell dysfunction via PINK1/Parkin-dependent mitophagy. |
| Q39079749 | St. John's wort extract and hyperforin protect rat and human pancreatic islets against cytokine toxicity |
| Q38050926 | Stress-induced self-cannibalism: on the regulation of autophagy by endoplasmic reticulum stress |
| Q42782106 | The bright side of reactive oxygen species: lifespan extension without cellular demise |
| Q48111881 | Ultrastructural alterations of pancreatic beta cells in human diabetes mellitus. |
| Q35527130 | Unsaturated fatty acids induce non-canonical autophagy |
| Q37448647 | tert-Butylhydroquinone (tBHQ) protects hepatocytes against lipotoxicity via inducing autophagy independently of Nrf2 activation |
| Q52607218 | β-Cell Autophagy in Diabetes Pathogenesis. |
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