scholarly article | Q13442814 |
review article | Q7318358 |
P2093 | author name string | Kenneth Maiese | |
P2860 | cites work | Resveratrol ameliorates diabetic vascular inflammation and macrophage infiltration in db/db mice by inhibiting the NF-κB pathway | Q87165662 |
Wnt-induced secreted protein 1/CCN4 in liver fibrosis both in vitro and in vivo | Q87408586 | ||
Simvastatin attenuates TNF‑α‑induced apoptosis in endothelial progenitor cells via the upregulation of SIRT1 | Q87649920 | ||
WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors | Q22008485 | ||
The deacetylase SIRT1 promotes membrane localization and activation of Akt and PDK1 during tumorigenesis and cardiac hypertrophy | Q24315832 | ||
AMPK phosphorylation of raptor mediates a metabolic checkpoint | Q24329244 | ||
Phosphoinositide 3-kinase as a novel functional target for the regulation of the insulin signaling pathway by SIRT1 | Q24337301 | ||
Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis | Q24601575 | ||
WISP-1 attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase | Q24672918 | ||
Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells | Q24810302 | ||
Erythropoietin: new directions for the nervous system | Q26828425 | ||
Cutting through the complexities of mTOR for the treatment of stroke | Q26851291 | ||
Targeting disease through novel pathways of apoptosis and autophagy | Q26864639 | ||
The regulation and deregulation of Wnt signaling by PARK genes in health and disease | Q26991986 | ||
Role of intensive glucose control in development of renal end points in type 2 diabetes mellitus: systematic review and meta-analysis intensive glucose control in type 2 diabetes | Q27004274 | ||
Shedding new light on neurodegenerative diseases through the mammalian target of rapamycin | Q27015640 | ||
Driving neural regeneration through the mammalian target of rapamycin | Q27027516 | ||
A scalable system for production of functional pancreatic progenitors from human embryonic stem cells | Q27302946 | ||
Epigenetic regulation of endothelial-cell-mediated vascular repair | Q28085420 | ||
Interleukin-18/WNT1-inducible signaling pathway protein-1 signaling mediates human saphenous vein smooth muscle cell proliferation | Q28118491 | ||
SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B | Q28251461 | ||
The Brain Hepatocyte Growth Factor/c-Met Receptor System: A New Target for the Treatment of Alzheimer's Disease | Q28256442 | ||
Palmitate activates autophagy in INS-1E β-cells and in isolated rat and human pancreatic islets | Q28483101 | ||
Cathepsin cleavage of sirtuin 1 in endothelial progenitor cells mediates stress-induced premature senescence | Q28508751 | ||
Induction of Wnt-inducible signaling protein-1 correlates with invasive breast cancer oncogenesis and reduced type 1 cell-mediated cytotoxic immunity: a retrospective study | Q28538654 | ||
CCN4 regulates vascular smooth muscle cell migration and proliferation | Q28567429 | ||
ERK and Akt signaling pathways are involved in advanced glycation end product-induced autophagy in rat vascular smooth muscle cells | Q28574192 | ||
Induction of manganese superoxide dismutase by nuclear translocation and activation of SIRT1 promotes cell survival in chronic heart failure | Q28577899 | ||
Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes | Q29616567 | ||
Protective effect of Dl-3n-butylphthalide on learning and memory impairment induced by chronic intermittent hypoxia-hypercapnia exposure | Q30582580 | ||
Ionizing radiation induces cellular senescence of articular chondrocytes via negative regulation of SIRT1 by p38 kinase | Q33569707 | ||
Vam3, a derivative of resveratrol, attenuates cigarette smoke-induced autophagy | Q33570831 | ||
Oxidative stress: Biomarkers and novel therapeutic pathways | Q33682262 | ||
Transcriptional control of antioxidant defense by the circadian clock | Q33687785 | ||
New strategies for Alzheimer's disease and cognitive impairment | Q33717008 | ||
SIRT1 is necessary for proficient telomere elongation and genomic stability of induced pluripotent stem cells | Q33730161 | ||
Diabetes mellitus: channeling care through cellular discovery | Q33749358 | ||
Huperzine A ameliorates cognitive deficits in streptozotocin-induced diabetic rats | Q33755620 | ||
FOXO3a governs early and late apoptotic endothelial programs during elevated glucose through mitochondrial and caspase signaling | Q33802721 | ||
An activator of mTOR inhibits oxLDL-induced autophagy and apoptosis in vascular endothelial cells and restricts atherosclerosis in apolipoprotein E⁻/⁻ mice | Q33827198 | ||
Acute metformin preconditioning confers neuroprotection against focal cerebral ischaemia by pre-activation of AMPK-dependent autophagy | Q33842696 | ||
Early apoptotic vascular signaling is determined by Sirt1 through nuclear shuttling, forkhead trafficking, bad, and mitochondrial caspase activation | Q33877687 | ||
Resveratrol protects vascular smooth muscle cells against high glucose-induced oxidative stress and cell proliferation in vitro | Q33893097 | ||
GLP1-derived nonapeptide GLP1(28-36)amide protects pancreatic β-cells from glucolipotoxicity | Q33893993 | ||
Erythropoietin action in stress response, tissue maintenance and metabolism | Q33907747 | ||
Wnt1 inducible signaling pathway protein 1 (WISP1) blocks neurodegeneration through phosphoinositide 3 kinase/Akt1 and apoptotic mitochondrial signaling involving Bad, Bax, Bim, and Bcl-xL | Q35742785 | ||
SIRT1: new avenues of discovery for disorders of oxidative stress | Q35757288 | ||
SIRT1 is required for oncogenic transformation of neural stem cells and for the survival of "cancer cells with neural stemness" in a p53-dependent manner. | Q35788756 | ||
Back to your heart: ubiquitin proteasome system-regulated signal transduction | Q35803035 | ||
Cellular demise and inflammatory microglial activation during beta-amyloid toxicity are governed by Wnt1 and canonical signaling pathways | Q35879541 | ||
Prevention of β-amyloid degeneration of microglia by erythropoietin depends on Wnt1, the PI 3-K/mTOR pathway, Bad, and Bcl-xL. | Q35947388 | ||
WISP1 (CCN4) autoregulates its expression and nuclear trafficking of β-catenin during oxidant stress with limited effects upon neuronal autophagy | Q35965763 | ||
Activating Akt and the brain's resources to drive cellular survival and prevent inflammatory injury | Q35971676 | ||
New avenues of exploration for erythropoietin | Q35999785 | ||
Nicotinamide-induced mitophagy: event mediated by high NAD+/NADH ratio and SIRT1 protein activation | Q36003773 | ||
Cardiovascular disease and mTOR signaling | Q36062316 | ||
Autophagy contributes to retardation of cardiac growth in diabetic rats | Q36076590 | ||
Group I metabotropic receptor neuroprotection requires Akt and its substrates that govern FOXO3a, Bim, and beta-catenin during oxidative stress | Q36088734 | ||
Mammalian target of rapamycin signaling in diabetic cardiovascular disease | Q36100715 | ||
Oxidative stress in the brain: novel cellular targets that govern survival during neurodegenerative disease | Q36121400 | ||
Discovery of nonsteroidal anti-inflammatory drug and anticancer drug enhancing reprogramming and induced pluripotent stem cell generation. | Q36165721 | ||
Fasting glucose, obesity, and coronary artery calcification in community-based people without diabetes | Q36181405 | ||
Winding through the WNT pathway during cellular development and demise | Q36305544 | ||
Wnt signaling promotes oncogenic transformation by inhibiting c-Myc-induced apoptosis | Q36324133 | ||
Driving cellular plasticity and survival through the signal transduction pathways of metabotropic glutamate receptors | Q36352348 | ||
A Critical Kinase Cascade in Neurological Disorders: PI 3-K, Akt, and mTOR. | Q36379761 | ||
Oxidant stress and signal transduction in the nervous system with the PI 3-K, Akt, and mTOR cascade | Q36432388 | ||
Cell Life versus cell longevity: the mysteries surrounding the NAD+ precursor nicotinamide | Q36447198 | ||
Wnt1 inducible signaling pathway protein 1 (WISP1) targets PRAS40 to govern β-amyloid apoptotic injury of microglia | Q36465550 | ||
Novel directions for diabetes mellitus drug discovery | Q36487424 | ||
mTOR: on target for novel therapeutic strategies in the nervous system | Q36501214 | ||
Obestatin induced recovery of myocardial dysfunction in type 1 diabetic rats: underlying mechanisms | Q36510182 | ||
UCP2, UCP3, avUCP, what do they do when proton transport is not stimulated? Possible relevance to pyruvate and glutamine metabolism. | Q36548834 | ||
Signaling molecules involved in lipid-induced pancreatic beta-cell dysfunction | Q36568896 | ||
Tuberous sclerosis protein 2 (TSC2) modulates CCN4 cytoprotection during apoptotic amyloid toxicity in microglia | Q36597635 | ||
WISP1 neuroprotection requires FoxO3a post-translational modulation with autoregulatory control of SIRT1 | Q36597808 | ||
Nitrosative stress plays an important role in Wnt pathway activation in diabetic retinopathy | Q36629924 | ||
Oxidative stress biology and cell injury during type 1 and type 2 diabetes mellitus | Q36663152 | ||
mTor is a signaling hub in cell survival: a mass-spectrometry-based proteomics investigation | Q39008937 | ||
Calotropin: a cardenolide from calotropis gigantea that inhibits Wnt signaling by increasing casein kinase 1α in colon cancer cells. | Q39014033 | ||
Canonical Wnt signaling skews TGF-β signaling in chondrocytes towards signaling via ALK1 and Smad 1/5/8. | Q39030668 | ||
SIRT1 knockdown promotes neural differentiation and attenuates the heat shock response. | Q39033591 | ||
A role for WNT1-inducible signaling protein-1 in airway remodeling in a rat asthma model | Q39127296 | ||
Phospho-mTOR: a novel target in regulation of renal lipid metabolism abnormality of diabetes | Q39130252 | ||
Magnolol protects against oxidative stress-mediated neural cell damage by modulating mitochondrial dysfunction and PI3K/Akt signaling | Q39195266 | ||
SIRT1 silencing confers neuroprotection through IGF-1 pathway activation | Q39202722 | ||
The human glucagon-like peptide-1 analogue liraglutide regulates pancreatic beta-cell proliferation and apoptosis via an AMPK/mTOR/P70S6K signaling pathway | Q39250821 | ||
Activation of Wnt/β-catenin pathway by exogenous Wnt1 protects SH-SY5Y cells against 6-hydroxydopamine toxicity | Q39259388 | ||
Inhibition of protein tyrosine phosphatase improves angiogenesis via enhancing Ang-1/Tie-2 signaling in diabetes | Q39372797 | ||
High expression of the longevity gene product SIRT1 and apoptosis induction by sirtinol in adult T-cell leukemia cells. | Q39398709 | ||
Sirtuin 1 regulates skeletal myoblast survival and enhances differentiation in the presence of resveratrol | Q39435920 | ||
The PI3K/Akt/mTOR pathway mediates retinal progenitor cell survival under hypoxic and superoxide stress | Q39564780 | ||
Upregulation of SIRT1 deacetylase in phenylephrine-treated cardiomyoblasts | Q39574693 | ||
Inhibition of Sirt1 promotes neural progenitors toward motoneuron differentiation from human embryonic stem cells | Q39622134 | ||
The CCN family of genes: a perspective on CCN biology and therapeutic potential | Q39670131 | ||
Erythropoietin prevents reactive oxygen species generation and renal tubular cell apoptosis at high glucose level | Q39671480 | ||
Physiological increases in uncoupling protein 3 augment fatty acid oxidation and decrease reactive oxygen species production without uncoupling respiration in muscle cells. | Q40392941 | ||
Uncoupling protein 3 (UCP3) stimulates glucose uptake in muscle cells through a phosphoinositide 3-kinase-dependent mechanism. | Q40816499 | ||
Angiogenic dysfunction in bone marrow-derived early outgrowth cells from diabetic animals is attenuated by SIRT1 activation | Q40881340 | ||
Erythropoietin attenuates advanced glycation endproducts-induced toxicity of Schwann cells in vitro | Q41587516 | ||
Induction of autophagy supports the bioenergetic demands of quiescent muscle stem cell activation | Q41768449 | ||
LRP5 negatively regulates differentiation of monocytes through abrogation of Wnt signalling | Q41768907 | ||
Enhancing AMPK activation during ischemia protects the diabetic heart against reperfusion injury | Q41855554 | ||
SIRT1 inhibition affects angiogenic properties of human MSCs | Q41964604 | ||
High glucose upregulation of early-onset Parkinson's disease protein DJ-1 integrates the PRAS40/TORC1 axis to mesangial cell hypertrophy | Q42073523 | ||
Abnormal gene expression and gene fusion in lung adenocarcinoma with high-throughput RNA sequencing | Q42238571 | ||
Angiotensin-converting-enzyme inhibition counteracts angiotensin II-mediated endothelial cell dysfunction by modulating the p38/SirT1 axis. | Q42282890 | ||
Stimulation of the follicular bulge LGR5+ and LGR6+ stem cells with the gut-derived human alpha defensin 5 results in decreased bacterial presence, enhanced wound healing, and hair growth from tissues devoid of adnexal structures | Q42447266 | ||
Nicotinic acid increases adiponectin secretion from differentiated bovine preadipocytes through G-protein coupled receptor signaling | Q42584211 | ||
Transplantation of SIRT1-engineered aged mesenchymal stem cells improves cardiac function in a rat myocardial infarction model | Q42672566 | ||
Evaluation of sirtuin role in neuroprotection of retinal ganglion cells in hypoxia. | Q42717654 | ||
SIRT1 is required for the effects of rapamycin on high glucose-inducing mesangial cells senescence | Q42718335 | ||
Xanthigen suppresses preadipocyte differentiation and adipogenesis through down-regulation of PPARγ and C/EBPs and modulation of SIRT-1, AMPK, and FoxO pathways | Q42801271 | ||
Mitochondrial nutrients improve immune dysfunction in the type 2 diabetic Goto-Kakizaki rats. | Q42914578 | ||
Tet1-mediated DNA demethylation regulates neuronal cell death induced by oxidative stress | Q43091712 | ||
Therapeutic targets for cancer: current concepts with PI 3-K, Akt, & mTOR. | Q43158408 | ||
Effects of caloric restriction on SIRT1 expression and apoptosis of islet beta cells in type 2 diabetic rats | Q43252091 | ||
High-fat diet and hydrochlorothiazide increase oxidative stress in brain of rats | Q43270394 | ||
Mechanisms of modified LDL-induced pericyte loss and retinal injury in diabetic retinopathy | Q43442147 | ||
Mitochondrial response to oxidative and nitrosative stress in early stages of diabetes | Q43775500 | ||
Delphinidin-3-glucoside protects human umbilical vein endothelial cells against oxidized low-density lipoprotein-induced injury by autophagy upregulation via the AMPK/SIRT1 signaling pathway | Q43898299 | ||
Respiratory uncoupling lowers blood pressure through a leptin-dependent mechanism in genetically obese mice | Q44030298 | ||
Dissociation of Bcl-2-Beclin1 complex by activated AMPK enhances cardiac autophagy and protects against cardiomyocyte apoptosis in diabetes | Q36720530 | ||
Triple play: promoting neurovascular longevity with nicotinamide, WNT, and erythropoietin in diabetes mellitus | Q36727444 | ||
Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt | Q36728127 | ||
The Wnt signaling pathway: aging gracefully as a protectionist? | Q36728844 | ||
Erythropoietin: elucidating new cellular targets that broaden therapeutic strategies | Q36740470 | ||
Mechanistic insights into diabetes mellitus and oxidative stress | Q36748171 | ||
The Src homology 2 domain tyrosine phosphatases SHP-1 and SHP-2: diversified control of cell growth, inflammation, and injury | Q36836455 | ||
Activated macrophages promote Wnt/β-catenin signaling in cholangiocarcinoma cells | Q36887069 | ||
SIRT1: recent lessons from mouse models. | Q36903847 | ||
Life span extension and neuronal cell protection by Drosophila nicotinamidase | Q36924185 | ||
The role of uncoupling proteins in diabetes mellitus | Q36942760 | ||
"Sly as a FOXO": new paths with Forkhead signaling in the brain | Q36944469 | ||
OutFOXOing disease and disability: the therapeutic potential of targeting FoxO proteins | Q36947037 | ||
Mild diabetes models and their maternal-fetal repercussions. | Q37009895 | ||
Diabetic stress: new triumphs and challenges to maintain vascular longevity | Q37032503 | ||
Enhanced tolerance against early and late apoptotic oxidative stress in mammalian neurons through nicotinamidase and sirtuin mediated pathways | Q37041649 | ||
FOXO1 competes with carbohydrate response element-binding protein (ChREBP) and inhibits thioredoxin-interacting protein (TXNIP) transcription in pancreatic beta cells | Q37095415 | ||
A "FOXO" in sight: targeting Foxo proteins from conception to cancer | Q37153195 | ||
Impaired autophagic function in rat islets with aging | Q37179931 | ||
Vascular injury during elevated glucose can be mitigated by erythropoietin and Wnt signaling | Q37182044 | ||
FoxO proteins: cunning concepts and considerations for the cardiovascular system | Q37195595 | ||
Effects of Resveratrol and trans-3,5,4'-Trimethoxystilbene on Glutamate-Induced Cytotoxicity, Heme Oxygenase-1, and Sirtuin 1 in HT22 Neuronal Cells | Q37224583 | ||
Mesenchymal stem cells conditioned with glucose depletion augments their ability to repair-infarcted myocardium | Q37296266 | ||
PPARα and Sirt1 mediate erythropoietin action in increasing metabolic activity and browning of white adipocytes to protect against obesity and metabolic disorders | Q37333503 | ||
The vitamin nicotinamide: translating nutrition into clinical care | Q37374047 | ||
A fork in the path: Developing therapeutic inroads with FoxO proteins | Q37390262 | ||
Dry age-related macular degeneration: mechanisms, therapeutic targets, and imaging | Q37395303 | ||
Different patterns of cerebral injury in dementia with or without diabetes | Q37397970 | ||
Tanshinol attenuates the deleterious effects of oxidative stress on osteoblastic differentiation via Wnt/FoxO3a signaling. | Q37486945 | ||
Metformin modulates hyperglycaemia-induced endothelial senescence and apoptosis through SIRT1. | Q37522894 | ||
Association study to evaluate FoxO1 and FoxO3 gene in CHD in Han Chinese | Q37525331 | ||
Aging increases CCN1 expression leading to muscle senescence | Q37575251 | ||
Mammalian target of rapamycin (mTOR) inhibition with rapamycin improves cardiac function in type 2 diabetic mice: potential role of attenuated oxidative stress and altered contractile protein expression. | Q37583506 | ||
Caloric restriction, SIRT1 and longevity | Q37588274 | ||
Nicotinamide-mediated inhibition of SIRT1 deacetylase is associated with the viability of cancer cells exposed to antitumor agents and apoptosis | Q35020234 | ||
Diabetes as a chronic metabolic stressor: causes, consequences and clinical complications | Q35032598 | ||
Dysfunctionally phosphorylated type 1 insulin receptor substrate in neural-derived blood exosomes of preclinical Alzheimer's disease | Q35039301 | ||
Improvement of cardiac functions by chronic metformin treatment is associated with enhanced cardiac autophagy in diabetic OVE26 mice | Q35043474 | ||
Reprogram or reboot: small molecule approaches for the production of induced pluripotent stem cells and direct cell reprogramming | Q35045767 | ||
Sirtuin 1 (SIRT1) protein degradation in response to persistent c-Jun N-terminal kinase 1 (JNK1) activation contributes to hepatic steatosis in obesity | Q35063067 | ||
The prevention of diabetic cardiomyopathy by non-mitogenic acidic fibroblast growth factor is probably mediated by the suppression of oxidative stress and damage | Q35070159 | ||
SIRT1 gene polymorphisms affect the protein expression in cardiovascular diseases | Q35109034 | ||
Erythropoietin employs cell longevity pathways of SIRT1 to foster endothelial vascular integrity during oxidant stress | Q35146283 | ||
Mammalian target of rapamycin: hitting the bull's-eye for neurological disorders | Q35157985 | ||
Protein kinase D1 (PKD1) phosphorylation promotes dopaminergic neuronal survival during 6-OHDA-induced oxidative stress. | Q35164624 | ||
Defective mitophagy in XPA via PARP-1 hyperactivation and NAD(+)/SIRT1 reduction. | Q35165995 | ||
Systemic treatment with erythropoietin protects the neurovascular unit in a rat model of retinal neurodegeneration | Q35205276 | ||
Hepatic Sirt1 deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance | Q35484801 | ||
FoxO1, the transcriptional chief of staff of energy metabolism | Q35587183 | ||
Erythropoietin mediated bone formation is regulated by mTOR signaling | Q35613027 | ||
Translating cell survival and cell longevity into treatment strategies with SIRT1 | Q35660308 | ||
Targeting cardiovascular disease with novel SIRT1 pathways | Q35661632 | ||
Erythropoietin and Wnt1 govern pathways of mTOR, Apaf-1, and XIAP in inflammatory microglia | Q35663684 | ||
Mapping autophagy on to your metabolic radar | Q35696469 | ||
Renoprotective effects of asialoerythropoietin in diabetic mice against ischaemia-reperfusion-induced acute kidney injury | Q84024575 | ||
Effect of chronic regular exercise on serum ischemia-modified albumin levels and oxidative stress in type 2 diabetes mellitus | Q84516608 | ||
Erythropoietin, forkhead proteins, and oxidative injury: biomarkers and biology | Q84627462 | ||
The gene polymorphisms of UCP1 but not PPAR γ and TCF7L2 are associated with diabetic retinopathy in Chinese type 2 diabetes mellitus cases | Q85663458 | ||
Epigenetics in the cerebrovascular system: changing the code without altering the sequence | Q86936374 | ||
WNT1-inducible signaling pathway protein-1 activates diverse cell survival pathways and blocks doxorubicin-induced cardiomyocyte death | Q33913340 | ||
Ablation of LKB1 in the heart leads to energy deprivation and impaired cardiac function | Q33945472 | ||
Sirt1 overexpression in neurons promotes neurite outgrowth and cell survival through inhibition of the mTOR signaling. | Q33986353 | ||
Early detection of undiagnosed diabetes mellitus: a US perspective | Q33996886 | ||
miR-34a regulates mouse neural stem cell differentiation | Q33998797 | ||
Alpha-lipoic acid as a pleiotropic compound with potential therapeutic use in diabetes and other chronic diseases | Q34012029 | ||
Resveratrol induces Sirt1-dependent apoptosis in 3T3-L1 preadipocytes by activating AMPK and suppressing AKT activity and survivin expression. | Q34089854 | ||
Autophagy: a double-edged sword for neuronal survival after cerebral ischemia | Q34096235 | ||
Erythropoietin, a novel versatile player regulating energy metabolism beyond the erythroid system | Q34100489 | ||
The neuroprotective effect of Klotho is mediated via regulation of members of the redox system | Q34107408 | ||
Diet control to achieve euglycemia induces significant loss of heart and liver weight via increased autophagy compared with ad libitum diet in diabetic rats | Q34116264 | ||
Neuroprotection with metformin and thymoquinone against ethanol-induced apoptotic neurodegeneration in prenatal rat cortical neurons | Q34133091 | ||
Intracellular molecular effects of insulin resistance in patients with metabolic syndrome | Q34133898 | ||
Wnt1 neuroprotection translates into improved neurological function during oxidant stress and cerebral ischemia through AKT1 and mitochondrial apoptotic pathways | Q34185844 | ||
Proline-rich Akt substrate of 40kDa (PRAS40): a novel downstream target of PI3k/Akt signaling pathway. | Q34215075 | ||
Mesenchymal stem cells: a revolution in therapeutic strategies of age-related diseases | Q34273600 | ||
Epidemiologic merit of obese-years, the combination of degree and duration of obesity | Q34324999 | ||
Melatonin regulates aging and neurodegeneration through energy metabolism, epigenetics, autophagy and circadian rhythm pathways | Q34358832 | ||
Dysfunction of endothelial progenitor cells from smokers and chronic obstructive pulmonary disease patients due to increased DNA damage and senescence | Q34360591 | ||
WISP1: Clinical insights for a proliferative and restorative member of the CCN family | Q34381111 | ||
Erythropoietin protects against diabetes through direct effects on pancreatic beta cells | Q34420833 | ||
PRAS40 is an integral regulatory component of erythropoietin mTOR signaling and cytoprotection | Q34429082 | ||
Anti-inflammatory agents to treat or prevent type 2 diabetes, metabolic syndrome and cardiovascular disease | Q34444895 | ||
Poor glycaemic control in type 2 diabetes patients reduces endothelial progenitor cell number by influencing SIRT1 signalling via platelet-activating factor receptor activation | Q34446306 | ||
Novel avenues of drug discovery and biomarkers for diabetes mellitus | Q34552287 | ||
FoxO1 mediates an autofeedback loop regulating SIRT1 expression | Q34568424 | ||
Resveratrol decreases fructose-induced oxidative stress, mediated by NADPH oxidase via an AMPK-dependent mechanism | Q34570751 | ||
Taking aim at Alzheimer's disease through the mammalian target of rapamycin | Q34603651 | ||
FoxO transcription factors support oxidative stress resistance in human chondrocytes | Q34626746 | ||
Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver | Q34813321 | ||
EPO relies upon novel signaling of Wnt1 that requires Akt1, FoxO3a, GSK-3β, and β-catenin to foster vascular integrity during experimental diabetes | Q34887803 | ||
Resistin promotes cardiac hypertrophy via the AMP-activated protein kinase/mammalian target of rapamycin (AMPK/mTOR) and c-Jun N-terminal kinase/insulin receptor substrate 1 (JNK/IRS1) pathways | Q34998025 | ||
Neuroprotective effects of resveratrol on damages of mouse cortical neurons induced by β-amyloid through activation of SIRT1/Akt1 pathway | Q35019476 | ||
Differential gene expression in Lin-/VEGF-R2+ bone marrow-derived endothelial progenitor cells isolated from diabetic mice | Q37589340 | ||
Metformin inhibits androgen-induced IGF-IR up-regulation in prostate cancer cells by disrupting membrane-initiated androgen signaling | Q37648017 | ||
SIRT1 positively regulates autophagy and mitochondria function in embryonic stem cells under oxidative stress | Q37710273 | ||
WNT1 inducible signaling pathway protein 1 (WISP1): A novel mediator linking development and disease | Q37812422 | ||
AMP-activated protein kinase: a potential player in Alzheimer's disease | Q37881988 | ||
Oxidative stress and diabetes mellitus | Q37910266 | ||
Role of sirtuins and calorie restriction in neuroprotection: implications in Alzheimer's and Parkinson's diseases | Q37929261 | ||
Platelet dysfunction in vascular pathologies and how can it be treated | Q37950545 | ||
Role of oxidative stress in diabetes-mediated vascular dysfunction: unifying hypothesis of diabetes revisited | Q38000380 | ||
Prevention of diabetes-induced cardiovascular complications upon treatment with antioxidants | Q38084184 | ||
Insulin resistance, oxidative stress and cardiovascular complications: role of sirtuins | Q38085400 | ||
Sirtuins: from metabolic regulation to brain aging | Q38124259 | ||
Caloric restriction and aging stem cells: the stick and the carrot? | Q38161233 | ||
Hypothalamic mTOR: the rookie energy sensor. | Q38162861 | ||
Role of protein tyrosine phosphatases in the modulation of insulin signaling and their implication in the pathogenesis of obesity-linked insulin resistance | Q38165106 | ||
Erythropoietin, a novel repurposed drug: an innovative treatment for wound healing in patients with diabetes mellitus | Q38182665 | ||
mTOR complex 1: a key player in neuroadaptations induced by drugs of abuse | Q38199194 | ||
The evolving role of the NAD+/nicotinamide metabolome in skin homeostasis, cellular bioenergetics, and aging | Q38209217 | ||
IRS2 integrates insulin/IGF1 signalling with metabolism, neurodegeneration and longevity | Q38247021 | ||
Modulating mTOR in aging and health | Q38262319 | ||
Protein tyrosine phosphatases in mast cell signaling | Q38267278 | ||
Crosstalk Between Endoplasmic Reticulum Stress, Oxidative Stress, and Autophagy: Potential Therapeutic Targets for Acute CNS Injuries | Q38284260 | ||
Dietary wolfberry ameliorates retinal structure abnormalities in db/db mice at the early stage of diabetes | Q38294227 | ||
Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes. | Q38299277 | ||
Cardiotrophin-1 eliminates hepatic steatosis in obese mice by mechanisms involving AMPK activation | Q38310226 | ||
Diabetes causes bone marrow autonomic neuropathy and impairs stem cell mobilization via dysregulated p66Shc and Sirt1. | Q38310944 | ||
Mitochondria are impaired in the adipocytes of type 2 diabetic mice | Q38315463 | ||
Gene expression after crush injury of human saphenous vein: using microarrays to define the transcriptional profile | Q38337438 | ||
Differential expression of the CCN family member WISP-1, WISP-2 and WISP-3 in human colorectal cancer and the prognostic implications. | Q38345070 | ||
Compound K protects pancreatic islet cells against apoptosis through inhibition of the AMPK/JNK pathway in type 2 diabetic mice and in MIN6 β-cells | Q38417600 | ||
A modified method of insulin producing cells' generation from bone marrow-derived mesenchymal stem cells | Q38939711 | ||
Adiponectin stimulates autophagy and reduces oxidative stress to enhance insulin sensitivity during high-fat diet feeding in mice. | Q38970746 | ||
Glucagon-like peptide-1 analog-mediated protection against cholesterol-induced apoptosis via mammalian target of rapamycin activation in pancreatic βTC-6 cells -1mTORβTC-6. | Q38987013 | ||
Erythropoietin is a novel vascular protectant through activation of Akt1 and mitochondrial modulation of cysteine proteases | Q44235661 | ||
Epidermal growth factor receptor transactivation is necessary for glucagon-like peptide-1 to protect PC12 cells from apoptosis | Q44271964 | ||
Arctigenin effectively ameliorates memory impairment in Alzheimer's disease model mice targeting both β-amyloid production and clearance | Q44328454 | ||
Inhibition of NF-kappaB activation by Pyrrolidine dithiocarbamate partially attenuates hippocampal MMP-9 activation and improves cognitive deficits in streptozotocin-induced diabetic rats | Q44476817 | ||
The SIRT1 deacetylase protects mice against the symptoms of metabolic syndrome | Q44666599 | ||
Wnt pathway regulation by long-term moderate exercise in rat hippocampus | Q44830482 | ||
Short-term exposure of high glucose concentration induces generation of reactive oxygen species in endothelial cells: implication for the oxidative stress associated with postprandial hyperglycemia | Q44961551 | ||
Oxidative stress parameters in blood, liver, and kidney of diabetic rats treated with curcumin and/or insulin. | Q45067766 | ||
Transcriptional characterization of Wnt pathway during sequential hepatic differentiation of human embryonic stem cells and adipose tissue-derived stem cells | Q45846364 | ||
Chronic treatment with recombinant human erythropoietin exerts renoprotective effects beyond hematopoiesis in streptozotocin-induced diabetic rat. | Q46056184 | ||
Phosphorylation of PRAS40-Thr246 involved in renal lipid accumulation of diabetes | Q46708537 | ||
AMPK activation ameliorates Alzheimer's disease-like pathology and spatial memory impairment in a streptozotocin-induced Alzheimer's disease model in rats | Q46853399 | ||
Effect of tempol on redox homeostasis and stress tolerance in mimetically aged Drosophila | Q46863991 | ||
High glucose condition induces autophagy in endothelial progenitor cells contributing to angiogenic impairment | Q46871351 | ||
AGEs induce caspase-mediated apoptosis of rat BMSCs via TNFα production and oxidative stress. | Q46974722 | ||
Nicotinamide treatment reduces the levels of oxidative stress, apoptosis, and PARP-1 activity in Aβ(1-42)-induced rat model of Alzheimer's disease. | Q46979323 | ||
IGF-1 gene-modified muscle-derived stem cells are resistant to oxidative stress via enhanced activation of IGF-1R/PI3K/AKT signaling and secretion of VEGF. | Q46982615 | ||
Involvement of the FoxO3a pathway in the ischemia/reperfusion injury of cardiac microvascular endothelial cells | Q47773731 | ||
The AKT/mTOR pathway mediates neuronal protective effects of erythropoietin in sepsis | Q47976704 | ||
SIRT1 regulates the neurogenic potential of neural precursors in the adult subventricular zone and hippocampus | Q48165385 | ||
Ac-cel, a novel antioxidant, protects against hydrogen peroxide-induced injury in PC12 cells via attenuation of mitochondrial dysfunction | Q48197064 | ||
HDAC2 selectively regulates FOXO3a-mediated gene transcription during oxidative stress-induced neuronal cell death | Q48233598 | ||
Early molecular and behavioral response to lipopolysaccharide in the WAG/Rij rat model of absence epilepsy and depressive-like behavior, involves interplay between AMPK, AKT/mTOR pathways and neuroinflammatory cytokine release | Q48259710 | ||
Identification of differentially expressed mRNA during pancreas regeneration of rat by mRNA differential display | Q48270277 | ||
Anxiety correlates to decreased blood and prefrontal cortex IGF-1 levels in streptozotocin induced diabetes | Q48309082 | ||
Ameliorating the effect of astragaloside IV on learning and memory deficit after chronic cerebral hypoperfusion in rats | Q48357939 | ||
Interactions between SIRT1 and MAPK/ERK regulate neuronal apoptosis induced by traumatic brain injury in vitro and in vivo | Q48430089 | ||
Age-dependent tissue expression patterns of Sirt1 in senescence-accelerated mice | Q48482724 | ||
The effect of regular exercise on antioxidant enzyme activities and lipid peroxidation levels in both hippocampi after occluding one carotid in rat. | Q48719131 | ||
SIRT1 expression in the cochlea and auditory cortex of a mouse model of age-related hearing loss | Q50356104 | ||
Hydroxyapatite coating affects the Wnt signaling pathway during peri-implant healing in vivo. | Q50800716 | ||
Serum levels of fetuin A and 8-hydroxydeoxyguanosine in morbidly obese subjects. | Q50908630 | ||
Dickkopf-1 (DKK1) phosphatase and tensin homolog on chromosome 10 (PTEN) crosstalk via microRNA interference in the diabetic heart. | Q51026386 | ||
The antiproliferative and apoptotic effects of sirtinol, a sirtuin inhibitor on human lung cancer cells by modulating Akt/β-catenin-Foxo3a axis. | Q51211036 | ||
Coagulanolide modulates hepatic glucose metabolism in C57BL/KsJ-db/db mice. | Q51350381 | ||
Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes. | Q51500191 | ||
Skeletal muscle respiratory uncoupling prevents diet-induced obesity and insulin resistance in mice. | Q54034693 | ||
Low-dose PTH increases osteoblast activity via decreased Mef2c/Sost in senescent osteopenic mice. | Q54197657 | ||
Enhanced CD4+CD25+ regulatory T cells with splenic proliferation and protection against oxidative stress by nicotinamide in gestational diabetes. | Q54329384 | ||
Metformin preconditioning protects Daphnia pulex from lethal hypoxic insult involving AMPK, HIF and mTOR signaling. | Q54512650 | ||
Autoreactive T cells induce necrosis and not BCL-2-regulated or death receptor-mediated apoptosis or RIPK3-dependent necroptosis of transplanted islets in a mouse model of type 1 diabetes. | Q55070749 | ||
Hypoxic macrophages impair autophagy in epithelial cells through Wnt1: relevance in IBD | Q57660541 | ||
High Glucose Induces Antioxidant Enzymes in Human Endothelial Cells in Culture: Evidence Linking Hyperglycemia and Oxidative Stress | Q58829353 | ||
Systemic autophagy insufficiency compromises adaptation to metabolic stress and facilitates progression from obesity to diabetes | Q59516123 | ||
The Wnt/beta-catenin pathway is activated during advanced arterial aging in humans | Q61912394 | ||
Adult neural precursors isolated from post mortem brain yield mostly neurons: An erythropoietin-dependent process | Q63481323 | ||
Stress in the brain: novel cellular mechanisms of injury linked to Alzheimer's disease | Q81860462 | ||
Mthfr deficiency induces endothelial progenitor cell senescence via uncoupling of eNOS and downregulation of SIRT1 | Q82948439 | ||
Protection of INS-1 cells from free fatty acid-induced apoptosis by targeting hOGG1 to mitochondria | Q82984554 | ||
Fibronectin potentiates topical erythropoietin-induced wound repair in diabetic mice | Q83422958 | ||
The many facets of cell injury: angiogenesis to autophagy | Q83929053 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | apoptotic process | Q14599311 |
autophagy | Q288322 | ||
P304 | page(s) | 173-188 | |
P577 | publication date | 2015-01-01 | |
P1433 | published in | Current neurovascular research | Q26842143 |
P1476 | title | Programming apoptosis and autophagy with novel approaches for diabetes mellitus | |
P478 | volume | 12 |
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