scholarly article | Q13442814 |
P50 | author | Jean-Louis Touraine | Q12923 |
Hervé Perron | Q110871612 | ||
P2093 | author name string | Jacques Portoukalian | |
Raphaële Germi | |||
Julie Medina | |||
Marine Seffals | |||
Thomas Piofczyk | |||
Sandrine Levet | |||
Julie Dimier | |||
Amandine Demolder | |||
Julie Joanou | |||
Kevin Réant | |||
Matthieu Normand | |||
Nelly Queruel | |||
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Recent advances in understanding Type 1 Diabetes | Q26766139 | ||
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The Juvenile Diabetes Research Foundation Network for Pancreatic Organ Donors with Diabetes (nPOD) Program: goals, operational model and emerging findings | Q27009048 | ||
Human endogenous retrovirus group E and its involvement in diseases | Q28082853 | ||
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Brains and peripheral blood mononuclear cells of multiple sclerosis (MS) patients hyperexpress MS-associated retrovirus/HERV-W endogenous retrovirus, but not Human herpesvirus 6. | Q33266667 | ||
Multiple sclerosis-associated retrovirus particles cause T lymphocyte-dependent death with brain hemorrhage in humanized SCID mice model | Q48388046 | ||
A placebo randomized controlled study to test the efficacy and safety of GNbAC1, a monoclonal antibody for the treatment of multiple sclerosis - Rationale and design | Q48505260 | ||
Detection of enterovirus in the islet cells of patients with type 1 diabetes: what do we learn from immunohistochemistry? Reply to Hansson SF, Korsgren S, Pontén F et al [letter]. | Q51852586 | ||
Circulating antibodies against an exocrine pancreatic enzyme in type 1 diabetes | Q73224777 | ||
Detection of endogenous retrovirus antigens in NOD mouse pancreatic beta-cells | Q74240570 | ||
Infrequency of detection of particle-associated MSRV/HERV-W RNA in the synovial fluid of patients with rheumatoid arthritis | Q74312784 | ||
Multiple sclerosis retrovirus particles and recombinant envelope trigger an abnormal immune response in vitro, by inducing polyclonal Vbeta16 T-lymphocyte activation | Q74449251 | ||
The IDDMK(1,2)22 retrovirus is not detectable in either mRNA or genomic DNA from patients with type 1 diabetes | Q77804985 | ||
Dysregulated Toll-like receptor expression and signaling in bone marrow-derived macrophages at the onset of diabetes in the non-obese diabetic mouse | Q83853916 | ||
The envelope protein of a human endogenous retrovirus-W family activates innate immunity through CD14/TLR4 and promotes Th1-like responses | Q83918234 | ||
Toll-like receptor 4 (TLR4) expression in human and murine pancreatic beta-cells affects cell viability and insulin homeostasis | Q33830986 | ||
Demonstration of increased toll-like receptor 2 and toll-like receptor 4 expression in monocytes of type 1 diabetes mellitus patients with microvascular complications | Q33937994 | ||
Lipopolysaccharides impair insulin gene expression in isolated islets of Langerhans via Toll-Like Receptor-4 and NF-κB signalling | Q34257301 | ||
Increased immune cell infiltration of the exocrine pancreas: a possible contribution to the pathogenesis of type 1 diabetes. | Q34393311 | ||
Blood and islet phenotypes indicate immunological heterogeneity in type 1 diabetes | Q34393377 | ||
Expression and activation by Epstein Barr virus of human endogenous retroviruses-W in blood cells and astrocytes: inference for multiple sclerosis | Q34427836 | ||
Human endogenous retrovirus protein activates innate immunity and promotes experimental allergic encephalomyelitis in mice | Q35063712 | ||
Beta cell expression of endogenous xenotropic retrovirus distinguishes diabetes-susceptible NOD/Lt from resistant NON/Lt mice | Q35612750 | ||
Toll-like receptor 4 on islet β cells senses expression changes in high-mobility group box 1 and contributes to the initiation of type 1 diabetes | Q35952134 | ||
Inflammatory response of endothelial cells to a human endogenous retrovirus associated with multiple sclerosis is mediated by TLR4. | Q36224032 | ||
Increased toll-like receptor (TLR) 2 and TLR4 expression in monocytes from patients with type 1 diabetes: further evidence of a proinflammatory state | Q36459935 | ||
The pathogenesis and natural history of type 1 diabetes | Q36526611 | ||
Insulitis and β-Cell Mass in the Natural History of Type 1 Diabetes. | Q36608775 | ||
Human endogenous retrovirus type W envelope expression in blood and brain cells provides new insights into multiple sclerosis disease. | Q36613374 | ||
Molecular identification of a novel retrovirus repeatedly isolated from patients with multiple sclerosis. The Collaborative Research Group on Multiple Sclerosis | Q36661594 | ||
Human Endogenous Retrovirus and Neuroinflammation in Chronic Inflammatory Demyelinating Polyradiculoneuropathy. | Q36869897 | ||
Type 1 diabetes as a relapsing-remitting disease? | Q36992950 | ||
The role of the innate immune system in destruction of pancreatic beta cells in NOD mice and humans with type I diabetes | Q36995532 | ||
The human endogenous retrovirus link between genes and environment in multiple sclerosis and in multifactorial diseases associating neuroinflammation | Q37583679 | ||
Pathogenesis of type 1 diabetes mellitus: interplay between enterovirus and host | Q37721131 | ||
Immune cell crosstalk in type 1 diabetes | Q37767586 | ||
CD4 T cell differentiation in type 1 diabetes. | Q38535279 | ||
The potential role of retroviruses in autoimmunity | Q38673415 | ||
The role of molecular mimicry and other factors in the association of Human Endogenous Retroviruses and autoimmunity | Q38714224 | ||
Type 1 diabetes pathogenesis is modulated by spontaneous autoimmune responses to endogenous retrovirus antigens in NOD mice | Q40382425 | ||
MSRV envelope protein is a potent, endogenous and pathogenic agonist of human toll-like receptor 4: Relevance of GNbAC1 in multiple sclerosis treatment | Q40921697 | ||
Human endogenous retrovirus-K contributes to motor neuron disease. | Q40971963 | ||
Enterovirus infection and type 1 diabetes: closing in on a link? | Q41290004 | ||
Human endogenous retrovirus W in brain lesions: Rationale for targeted therapy in multiple sclerosis | Q42050724 | ||
Low HERV-K(C4) copy number is associated with type 1 diabetes | Q42242979 | ||
Human cytomegalovirus (HCMV) induces human endogenous retrovirus (HERV) transcription | Q42256195 | ||
Evaluation of the fidelity of immunolabelling obtained with clone 5D8/1, a monoclonal antibody directed against the enteroviral capsid protein, VP1, in human pancreas. | Q42257763 | ||
Glucose Sensitivity and Metabolism-Secretion Coupling Studied during Two-Year Continuous Culture in INS-1E Insulinoma Cells | Q42798453 | ||
Isolation of retrovirus from patients with multiple sclerosis | Q44459265 | ||
No evidence for association between IDDMK(1,2)22, a novel isolated retrovirus, and IDDM. | Q44834533 | ||
Human endogenous retrovirus type W envelope protein inhibits oligodendroglial precursor cell differentiation | Q45193847 | ||
Regulation of human endogenous retrovirus W protein expression by herpes simplex virus type 1: implications for multiple sclerosis | Q45418058 | ||
Detection of enterovirus in the islet cells of patients with type 1 diabetes: what do we learn from immunohistochemistry? | Q46087400 | ||
Pancreas organ weight in individuals with disease-associated autoantibodies at risk for type 1 diabetes. | Q47266966 | ||
Human endogenous retrovirus with a high genomic sequence homology with IDDMK(1,2)22 is not specific for Type I (insulin-dependent) diabetic patients but ubiquitous | Q47967171 | ||
A human endogenous retroviral superantigen as candidate autoimmune gene in type I diabetes | Q48047077 | ||
P433 | issue | 17 | |
P921 | main subject | type-1 diabetes | Q124407 |
P577 | publication date | 2017-09-07 | |
P1433 | published in | JCI insight | Q27727187 |
P1476 | title | An ancestral retroviral protein identified as a therapeutic target in type-1 diabetes | |
P478 | volume | 2 |
Q64104092 | Anti-HERV-W antibodies are correlated with seroreactivity against Mycobacterium avium subsp. paratuberculosis in children and youths at T1D risk |
Q91693298 | Endogenous Retroviruses Activity as a Molecular Signature of Neurodevelopmental Disorders |
Q52338720 | HERV Envelope Proteins: Physiological Role and Pathogenic Potential in Cancer and Autoimmunity. |
Q58610985 | HERV-W env regulates calcium influx via activating TRPC3 channel together with depressing DISC1 in human neuroblastoma cells |
Q58754303 | Human Endogenous Retroviruses Are Ancient Acquired Elements Still Shaping Innate Immune Responses |
Q52351424 | Human Endogenous Retroviruses in Neurological Diseases. |
Q60046088 | Induction of Proinflammatory Multiple Sclerosis-Associated Retrovirus Envelope Protein by Human Herpesvirus-6A and CD46 Receptor Engagement |
Q64078328 | Quantitative analysis of human endogenous retrovirus-K transcripts in postmortem premotor cortex fails to confirm elevated expression of HERV-K RNA in amyotrophic lateral sclerosis |
Q58552569 | Rabbit models of human diseases for diagnostics and therapeutics development |
Q60044236 | Variation in proviral content among human genomes mediated by LTR recombination |
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