Silencing of NHE-1 blunts the slow force response to myocardial stretch

scientific journal article

Silencing of NHE-1 blunts the slow force response to myocardial stretch is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/JAPPLPHYSIOL.01344.2010
P3181OpenCitations bibliographic resource ID2966094
P698PubMed publication ID21659487
P5875ResearchGate publication ID51206983

P50authorIrene Lucía EnnisQ61818239
Horacio E. CingolaniQ61818419
Enrique PortianskyQ63985118
María Celeste Villa-AbrilleQ96778417
P2093author name stringBernardo V. Alvarez
Eugenio Cingolani
Mariela B. Nolly
Mirian C. Roldan
Néstor G. Pérez
P2860cites workFunctional relevance of the stretch-dependent slow force response in failing human myocardiumQ24337669
Homeometric autoregulation in the heartQ28186725
On the part played by the suprarenals in the normal vascular reactions of the bodyQ28264962
Lentiviral vectors bearing the cardiac promoter of the Na+-Ca2+ exchanger report cardiogenic differentiation in stem cellsQ30489102
Reverse mode of the Na+-Ca2+ exchange after myocardial stretch: underlying mechanism of the slow force responseQ32069232
The cardiac Na-H exchanger: a key downstream mediator for the cellular hypertrophic effects of paracrine, autocrine and hormonal factorsQ36021514
Intracellular signaling following myocardial stretch: an autocrine/paracrine loopQ36101331
Prevention of cardiac hypertrophy and heart failure by silencing of NF-kappaB.Q36514490
Early signals after stretch leading to cardiac hypertrophy. Key role of NHE-1.Q37175842
Involvement of transient receptor potential canonical 1 (TRPC1) in angiotensin II-induced vascular smooth muscle cell hypertrophyQ38304952
Reactive oxygen species-mediated regulation of the Na+-H+ exchanger 1 gene expression connects intracellular redox status with cells' sensitivity to death triggersQ40369823
Mitochondrial reactive oxygen species activate the slow force response to stretch in feline myocardiumQ42518441
The Anrep effect requires transactivation of the epidermal growth factor receptorQ43128882
Upregulation of myocardial Na+/H+ exchanger induced by chronic treatment with a selective inhibitorQ44216143
Activation of Na+-H+ exchange and stretch-activated channels underlies the slow inotropic response to stretch in myocytes and muscle from the rat heartQ44964647
Non-cell-autonomous effects of vector-expressed regulatory RNAs in mammalian heart cellsQ45886047
Na+/H+ exchanger-1 inhibitors decrease myocardial superoxide production via direct mitochondrial actionQ46359215
Streptomycin and intracellular calcium modulate the response of single guinea-pig ventricular myocytes to axial stretchQ46400490
Mechanical deformation of ventricular myocytes modulates both TRPC6 and Kir2.3 channelsQ46477997
Stretch-dependent modulation of [Na+]i, [Ca2+]i, and pHi in rabbit myocardium--a mechanism for the slow force responseQ46649569
Stretch-activated currents in ventricular myocytes: amplitude and arrhythmogenic effects increase with hypertrophyQ46879343
Mechanically activated currents in chick heart cellsQ47915035
Effects of Mechanical Stretch on Membrane Currents of Single Ventricular Myocytes of Guinea-Pig HeartQ53851836
Connexin-specific cell-to-cell transfer of short interfering RNA by gap junctionsQ59212248
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)874–880
P577publication date2011-09-01
P1433published inJournal of Applied PhysiologyQ1091719
P1476titleSilencing of NHE-1 blunts the slow force response to myocardial stretch
P478volume111

Reverse relations

cites work (P2860)
Q38902443Cardiac hypertrophy reduction in SHR by specific silencing of myocardial Na(+)/H(+) exchanger
Q90638692Disruption of Transverse-Tubules Eliminates the Slow Force Response to Stretch in Isolated Rat Trabeculae
Q47949599Effect of SR load and pH regulatory mechanisms on stretch-dependent Ca(2+) entry during the slow force response
Q43617419Endogenous endothelin 1 mediates angiotensin II-induced hypertrophy in electrically paced cardiac myocytes through EGFR transactivation, reactive oxygen species and NHE-1.
Q37434706Epidermal Growth Factor Receptor Silencing Blunts the Slow Force Response to Myocardial Stretch
Q50958775Inhibition of carbonic anhydrase prevents the Na(+)/H(+) exchanger 1-dependent slow force response to rat myocardial stretch.
Q35128221Lactosylceramide promotes hypertrophy through ROS generation and activation of ERK1/2 in cardiomyocytes
Q42499067Mineralocorticoid receptor activation is crucial in the signalling pathway leading to the Anrep effect
Q39391125Mitochondrial NHE1: a newly identified target to prevent heart disease
Q36369248Sevoflurane post-conditioning reduces rat myocardial ischemia reperfusion injury through an increase in NOS and a decrease in phopshorylated NHE1 levels
Q91143412Silencing of the Na+/H+ exchanger 1(NHE-1) prevents cardiac structural and functional remodeling induced by angiotensin II
Q90601641The lack of slow force response in failing rat myocardium: role of stretch-induced modulation of Ca-TnC kinetics
Q46957433The signaling pathway for aldosterone-induced mitochondrial production of superoxide anion in the myocardium
Q36873848The zebrafish as a novel animal model to study the molecular mechanisms of mechano-electrical feedback in the heart

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