The zebrafish as a novel animal model to study the molecular mechanisms of mechano-electrical feedback in the heart

scientific article published on 23 July 2012

The zebrafish as a novel animal model to study the molecular mechanisms of mechano-electrical feedback in the heart is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.PBIOMOLBIO.2012.07.006
P932PMC publication ID3663588
P698PubMed publication ID22835662
P5875ResearchGate publication ID230572391

P2093author name stringAndreas A Werdich
Darwin Jeyaraj
Brian M McDermott
David S Rosenbaum
Calum A Macrae
Xiaoping Wan
Eckhard Ficker
M Khaled Sabeh
Anna Brzezinski
P2860cites workFactors affecting epicardial dispersion of repolarization: a mapping study in the isolated porcine heartQ57249934
Mechanisms of Abnormal Systolic Motion of the Interventricular Septum During Left Bundle-Branch BlockQ58867615
Absence of pressure overload induced myocardial hypertrophy after conditional inactivation of Gαq/Gα11 in cardiomyocytesQ60687218
Stretching cardiac myocytes stimulates protooncogene expressionQ67271278
T-wave changes after artificial pacingQ70105616
Sequence and timing of ventricular wall motion in patients with bundle branch block. Assessment by radionuclide cineangiographyQ70475909
Mechanical stretch activates the stress-activated protein kinases in cardiac myocytesQ71057752
Endocardial activation of left bundle branch blockQ71294256
Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryoQ73010073
Mechanisms underlying the increase in force and Ca(2+) transient that follow stretch of cardiac muscle: a possible explanation of the Anrep effectQ73082825
Spread of electrical activity through the wall of the ventricleQ73328005
Stretch-induced excitation and action potential changes of single cardiac cellsQ73355455
Genomics. Sanger will sequence zebrafish genomeQ73458581
Alterations in Ca2+ cycling proteins and G alpha q signaling after left ventricular assist device support in failing human heartsQ73573690
Spread of excitation during premature ventricular systolesQ73790953
Regional alterations in protein expression in the dyssynchronous failing heartQ73821989
Left ventricular dysfunction after long-term right ventricular apical pacing in the youngQ74070170
Pulsatile stretch remodels cell-to-cell communication in cultured myocytesQ74188051
Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophyQ74469678
The slow mo mutation reduces pacemaker current and heart rate in adult zebrafishQ74514707
Asynchronous electrical activation induces asymmetrical hypertrophy of the left ventricular wallQ77133126
Pulsatile stretch stimulates vascular endothelial growth factor (VEGF) secretion by cultured rat cardiac myocytesQ77906028
Mechanical stretch and angiotensin II differentially upregulate the renin-angiotensin system in cardiac myocytes In vitroQ78031794
Membrane potential of rat ventricular myocytes responds to axial stretch in phase, amplitude and speed-dependent mannersQ79284696
Single cell mechanics of rat cardiomyocytes under isometric, unloaded, and physiologically loaded conditionsQ79735185
Reduced expression of regulator of G-protein signaling 2 (RGS2) in hypertensive patients increases calcium mobilization and ERK1/2 phosphorylation induced by angiotensin IIQ83311058
Rainbow trout myocardium does not exhibit a slow inotropic response to stretchQ83573763
Prevalence and determinants of left ventricular systolic dyssynchrony in patients with normal ejection fraction received right ventricular apical pacing: a real-time three-dimensional echocardiographic studyQ84940444
Basic Mechanisms of Cardiac Impulse Propagation and Associated ArrhythmiasQ22337019
TRP-ing up heart and vessels: canonical transient receptor potential channels and cardiovascular diseaseQ24624455
Wnt11 patterns a myocardial electrical gradient through regulation of the L-type Ca(2+) channelQ24632619
Morphants: a new systematic vertebrate functional genomics approachQ24645978
Targeted gene inactivation in zebrafish using engineered zinc-finger nucleasesQ24647647
Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fractionQ28208692
Cardiac excitation-contraction couplingQ28216347
Canonical transient receptor potential channels promote cardiomyocyte hypertrophy through activation of calcineurin signalingQ28261648
Large scale genetics in a small vertebrate, the zebrafishQ28286020
Genome editing with engineered zinc finger nucleasesQ28290795
Silencing of NHE-1 blunts the slow force response to myocardial stretchQ28575938
Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in miceQ28594677
Effective targeted gene 'knockdown' in zebrafishQ29547445
Regulation of cardiac hypertrophy by intracellular signalling pathwaysQ29615166
Chronic ventricular pacing in children: toward prevention of pacing-induced heart diseaseQ30475471
TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophyQ30478281
Human cardiomyopathy mutations induce myocyte hyperplasia and activate hypertrophic pathways during cardiogenesis in zebrafishQ30500300
The regenerative capacity of zebrafish reverses cardiac failure caused by genetic cardiomyocyte depletion.Q30502828
Local tissue geometry determines contractile force generation of engineered muscle networksQ30513853
Stretch-induced actin remodeling requires targeting of zyxin to stress fibers and recruitment of actin regulatorsQ30514032
Axial stretch of rat single ventricular cardiomyocytes causes an acute and transient increase in Ca2+ spark rateQ30529903
Estimation of conduction velocity vector fields from epicardial mapping dataQ32064457
Blebbistatin effectively uncouples the excitation-contraction process in zebrafish embryonic heartQ33544983
Mechanisms of enhanced beta-adrenergic reserve from cardiac resynchronization therapyQ33771680
Increased phosphorylation of tropomyosin, troponin I, and myosin light chain-2 after stretch in rabbit ventricular myocardium under physiological conditions.Q33788191
Pathophysiology and clinical implications of cardiac memoryQ33833631
TRPC1 channels are critical for hypertrophic signaling in the heartQ33896913
Novel insights into the mechanisms mediating the local antihypertrophic effects of cardiac atrial natriuretic peptide: role of cGMP-dependent protein kinase and RGS2.Q34044364
The art and design of genetic screens: zebrafishQ34104121
Canonical TRP channels and mechanotransduction: from physiology to disease states.Q34116745
Calcium handling in zebrafish ventricular myocytesQ34142132
Dual-chamber pacing or ventricular backup pacing in patients with an implantable defibrillator: the Dual Chamber and VVI Implantable Defibrillator (DAVID) TrialQ34166289
Effect of epicardial or biventricular pacing to prolong QT interval and increase transmural dispersion of repolarization: does resynchronization therapy pose a risk for patients predisposed to long QT or torsade de pointes?Q34176456
Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failureQ34321811
Cardiac resynchronization in chronic heart failureQ34524008
The transformation of the model organism: a decade of developmental geneticsQ34531721
Primary contribution to zebrafish heart regeneration by gata4(+) cardiomyocytes.Q34618217
From Zebrafish to human: modular medical modelsQ34762651
Assessment of contractility in intact ventricular cardiomyocytes using the dimensionless 'Frank-Starling Gain' indexQ35042536
Cardiac resynchronization therapy in patients with mild heart failure: a systematic review and meta-analysis of randomized controlled trialsQ35151253
Effects of mechanical forces and mediators of hypertrophy on remodeling of gap junctions in the heartQ35697303
Quantitative comparison of cardiac ventricular myocyte electrophysiology and response to drugs in human and nonhuman species.Q35850064
Defective "pacemaker" current (Ih) in a zebrafish mutant with a slow heart rateQ36139196
The cellular basis for enhanced volume-modulated cardiac output in fish heartsQ36295777
Effects of mechanosensitive ion channels on ventricular electrophysiology: experimental and theoretical modelsQ36366174
Focal adhesions: paradigm for a signaling nexusQ36423637
Optical imaging of arrhythmias in tissue cultureQ36610170
Cell cultures as models of cardiac mechanoelectric feedbackQ37126911
Responses of single-ventricular myocytes to dynamic axial stretchingQ37159932
Calcineurin-dependent cardiomyopathy is activated by TRPC in the adult mouse heartQ37219493
Mechanisms linking short- and long-term electrical remodeling in the heart...is it a stretch?Q37292219
Sensing pressure in the cardiovascular system: Gq-coupled mechanoreceptors and TRP channels.Q37432783
Zebrafish genetic models for arrhythmiaQ37436614
Large animal models of heart failure: a critical link in the translation of basic science to clinical practiceQ37609687
Ontogeny of cardiovascular and respiratory physiology in lower vertebratesQ37739393
Mechanotransduction: the role of mechanical stress, myocyte shape, and cytoskeletal architecture on cardiac functionQ37866169
Targeted gene therapy for the treatment of heart failureQ37878086
Right ventricular pacing, mechanical dyssynchrony, and heart failureQ37970622
G protein-mediated stretch receptionQ37973988
TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodelingQ39076684
Effect of changes in load on monophasic action potential and segment length of pig heart in situQ39277027
Methods for Human Embryonic Stem Cells Derived Cardiomyocytes Cultivation, Genetic Manipulation, and TransplantationQ39672330
Mechanical stretch rapidly activates multiple signal transduction pathways in cardiac myocytes: potential involvement of an autocrine/paracrine mechanismQ40872674
The cellular and molecular response of cardiac myocytes to mechanical stress.Q41388060
Angiotensin II AT1 receptor internalization, translocation and de novo synthesis modulate cytosolic and nuclear calcium in human vascular smooth muscle cells.Q42440787
Silencing regulator of G protein signaling-2 (RGS-2) increases angiotensin II signaling: insights into hypertension from findings in Bartter's/Gitelman's syndromes.Q42526548
A novel method to study contraction characteristics of a single cardiac myocyte using carbon fibersQ43713948
Anisotropic stretch-induced hypertrophy in neonatal ventricular myocytes micropatterned on deformable elastomersQ44270507
Headwaters of the zebrafish -- emergence of a new model vertebrateQ44419286
Identification and expression analysis of kcnh2 genes in the zebrafishQ44516817
Ventricular filling slows epicardial conduction and increases action potential duration in an optical mapping study of the isolated rabbit heart.Q44557314
Mechanical loading stimulates cell hypertrophy and specific gene expression in cultured rat cardiac myocytes. Possible role of protein kinase C activationQ44647086
Activation of Na+-H+ exchange and stretch-activated channels underlies the slow inotropic response to stretch in myocytes and muscle from the rat heartQ44964647
Cardiac troponin T is essential in sarcomere assembly and cardiac contractilityQ46049216
Axial stretch enhances sarcoplasmic reticulum Ca2+ leak and cellular Ca2+ reuptake in guinea pig ventricular myocytes: experiments and modelsQ46229676
Importance of spatiotemporal heterogeneity of cellular restitution in mechanism of arrhythmogenic discordant alternansQ46329127
Stretch-dependent modulation of [Na+]i, [Ca2+]i, and pHi in rabbit myocardium--a mechanism for the slow force responseQ46649569
The UCS factor Steif/Unc-45b interacts with the heat shock protein Hsp90a during myofibrillogenesisQ47073713
Mutations affecting the cardiovascular system and other internal organs in zebrafishQ47073714
Angiotensin II-mediated adaptive and maladaptive remodeling of cardiomyocyte excitation-contraction couplingQ47701606
Adverse effect of ventricular pacing on heart failure and atrial fibrillation among patients with normal baseline QRS duration in a clinical trial of pacemaker therapy for sinus node dysfunctionQ47866464
Stretch-induced regional mechanoelectric dispersion and arrhythmia in the right ventricle of anesthetized lambsQ48915203
Detrimental ventricular remodeling in patients with congenital complete heart block and chronic right ventricular apical pacingQ48957366
New-onset heart failure after permanent right ventricular apical pacing in patients with acquired high-grade atrioventricular block and normal left ventricular function.Q50862411
Long-term effect of right ventricular pacing on myocardial perfusion and function.Q50963803
Temporal characteristics of cardiac memory in humans: vectorcardiographic quantification in a model of cardiac pacing.Q51492175
T wave changes persisting after ventricular pacing in canine heart are altered by 4-aminopyridine but not by lidocaine. Implications with respect to phenomenon of cardiac 'memory'Q51693542
Altered ventricular stretch contributes to initiation of cardiac memory.Q51969087
Mechanoelectrical feedback as novel mechanism of cardiac electrical remodeling.Q51974499
Altering ventricular activation remodels gap junction distribution in canine heart.Q52019504
Embryonic and larval expression of zebrafish voltage-gated sodium channel alpha-subunit genes.Q52020738
Cardiac memory: a mechanical and electrical phenomenon.Q52043327
"Physiological genomics": mutant screens in zebrafish.Q52185598
Disruption of hemoglobin oxygen transport does not impact oxygen-dependent physiological processes in developing embryos of zebra fish (Danio rerio).Q52200549
Electrotonic modulation of the T wave and cardiac memory.Q52220359
Cardiac tissue geometry as a determinant of unidirectional conduction block: assessment of microscopic excitation spread by optical mapping in patterned cell cultures and in a computer modelQ52343580
Force-length relations in isolated intact cardiomyocytes subjected to dynamic changes in mechanical load.Q53584942
P433issue2-3
P921main subjectDanio rerioQ169444
P304page(s)154-165
P577publication date2012-07-23
P1433published inProgress in Biophysics and Molecular BiologyQ15753863
P1476titleThe zebrafish as a novel animal model to study the molecular mechanisms of mechano-electrical feedback in the heart
P478volume110