scholarly article | Q13442814 |
P2093 | author name string | Hiroyuki Kobayashi | |
Yasuo Mori | |||
Hideki Sumimoto | |||
Hitoshi Kurose | |||
Motohiro Nishida | |||
Yoji Sato | |||
Ryuji Inoue | |||
Taku Nagao | |||
Naoya Onohara | |||
P2860 | cites work | Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol | Q22001504 |
Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth | Q24309615 | ||
Subunit composition of mammalian transient receptor potential channels in living cells | Q24530559 | ||
A simplified system for generating recombinant adenoviruses | Q24682328 | ||
NFAT signaling: choreographing the social lives of cells | Q28216151 | ||
Regulation of TRPC6 channel activity by tyrosine phosphorylation | Q28242371 | ||
Canonical transient receptor potential channels promote cardiomyocyte hypertrophy through activation of calcineurin signaling | Q28261648 | ||
A calcineurin-dependent transcriptional pathway for cardiac hypertrophy | Q28269300 | ||
Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy | Q28343890 | ||
Differential regulation of transient receptor potential melastatin 6 and 7 cation channels by ANG II in vascular smooth muscle cells from spontaneously hypertensive rats | Q28569103 | ||
Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro | Q28570955 | ||
G alpha(i) and G alpha(o) are target proteins of reactive oxygen species | Q28574404 | ||
Galpha(12/13) mediates alpha(1)-adrenergic receptor-induced cardiac hypertrophy | Q28611521 | ||
TRP channels as cellular sensors | Q29615917 | ||
Differential activation of transcription factors induced by Ca2+ response amplitude and duration | Q29619010 | ||
The transient receptor potential protein homologue TRP6 is the essential component of vascular alpha(1)-adrenoceptor-activated Ca(2+)-permeable cation channel | Q30979449 | ||
Signaling to the nucleus by an L-type calcium channel-calmodulin complex through the MAP kinase pathway | Q34094970 | ||
Cytoplasmic signaling pathways that regulate cardiac hypertrophy | Q34142151 | ||
A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis | Q34416768 | ||
Receptor-operated Ca2(+)-permeable nonselective cation channels in vascular smooth muscle: a physiologic perspective | Q34657139 | ||
Excitation-transcription coupling: signaling by ion channels to the nucleus | Q35049919 | ||
Calcium-calcineurin signaling in the regulation of cardiac hypertrophy | Q35874296 | ||
Ins(1,4,5)P3 receptors and inositol phosphates in the heart-evolutionary artefacts or active signal transducers? | Q36134444 | ||
Inositol 1,4,5-trisphosphate receptor expression in cardiac myocytes | Q36233054 | ||
Amplification of receptor signalling by Ca2+ entry-mediated translocation and activation of PLCgamma2 in B lymphocytes. | Q36245720 | ||
Sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA) gene silencing and remodeling of the Ca2+ signaling mechanism in cardiac myocytes | Q37621106 | ||
NFAT functions as a working memory of Ca2+ signals in decoding Ca2+ oscillation | Q39804742 | ||
Heteromultimeric TRPC6-TRPC7 channels contribute to arginine vasopressin-induced cation current of A7r5 vascular smooth muscle cells | Q40280966 | ||
Multiple regulation by calcium of murine homologues of transient receptor potential proteins TRPC6 and TRPC7 expressed in HEK293 cells | Q40484838 | ||
A novel recombinant hyperaffinity inositol 1,4,5-trisphosphate (IP(3)) absorbent traps IP(3), resulting in specific inhibition of IP(3)-mediated calcium signaling | Q40763852 | ||
Rapid shuttling of NF-AT in discrimination of Ca2+ signals and immunosuppression | Q41157105 | ||
The effects of modulation of calcium influx through the voltage-sensitive calcium channel on cardiomyocyte hypertrophy | Q41674521 | ||
Transient receptor potential melastatin 7 ion channels regulate magnesium homeostasis in vascular smooth muscle cells: role of angiotensin II. | Q42471701 | ||
Pharmacological activation of plasma-membrane KATP channels reduces reoxygenation-induced Ca(2+) overload in cardiac myocytes via modulation of the diastolic membrane potential | Q43263045 | ||
Capacitative calcium entry contributes to nuclear factor of activated T-cells nuclear translocation and hypertrophy in cardiomyocytes | Q43876941 | ||
Signaling microdomains define the specificity of receptor-mediated InsP(3) pathways in neurons | Q43968738 | ||
Activation of the Ca(2+)-activated nonselective cation channel by diacylglycerol analogues in rat cardiomyocytes | Q44805004 | ||
TRPC3 mediates pyrimidine receptor-induced depolarization of cerebral arteries | Q45190188 | ||
Amlodipine ameliorates myocardial hypertrophy by inhibiting EGFR phosphorylation | Q45225661 | ||
G alpha 12/13- and reactive oxygen species-dependent activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase by angiotensin receptor stimulation in rat neonatal cardiomyocytes. | Q45295556 | ||
Increased 1,4-dihydropyridine binding sites in serum-stimulated cardiomyocyte hypertrophy. | Q46170063 | ||
Galpha12/13-mediated production of reactive oxygen species is critical for angiotensin receptor-induced NFAT activation in cardiac fibroblasts. | Q46435005 | ||
Role of endogenous TRPC6 channels in Ca2+ signal generation in A7r5 smooth muscle cells. | Q46735379 | ||
Voltage-dependent calcium influx in human sperm assessed by simultaneous optical detection of intracellular calcium and membrane potential | Q47891172 | ||
Intracardiac detection of angiotensinogen and renin: a localized renin-angiotensin system in neonatal rat heart | Q67567248 | ||
Differential requirement of G alpha12, G alpha13, G alphaq, and G beta gamma for endothelin-1-induced c-Jun NH2-terminal kinase and extracellular signal-regulated kinase activation | Q73049257 | ||
Transient receptor potential channels regulate myogenic tone of resistance arteries | Q77678843 | ||
Dexamethasone-induced hypertrophy in rat neonatal cardiac myocytes involves an elevated L-type Ca(2+)current | Q78050100 | ||
P433 | issue | 22 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 5305-5316 | |
P577 | publication date | 2006-11-02 | |
P1433 | published in | The EMBO Journal | Q1278554 |
P1476 | title | TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy | |
P478 | volume | 25 |
Q26781720 | "TRP inflammation" relationship in cardiovascular system |
Q91637779 | A TR(i)P to Cell Migration: New Roles of TRP Channels in Mechanotransduction and Cancer |
Q35546884 | A cardiac pathway of cyclic GMP-independent signaling of guanylyl cyclase A, the receptor for atrial natriuretic peptide |
Q46611820 | A novel signaling pathway of ADP-ribosyl cyclase activation by angiotensin II in adult rat cardiomyocytes |
Q30492499 | A pathogenic C terminus-truncated polycystin-2 mutant enhances receptor-activated Ca2+ entry via association with TRPC3 and TRPC7 |
Q38173671 | A pathway and network review on beta-adrenoceptor signaling and beta blockers in cardiac remodeling |
Q42436589 | ATP/UTP activate cation-permeable channels with TRPC3/7 properties in rat cardiomyocytes. |
Q39743095 | Accelerated development of pressure overload-induced cardiac hypertrophy and dysfunction in an RyR2-R176Q knockin mouse model |
Q52430882 | Activation of Myofibroblast TRPA1 by Steroids and Pirfenidone Ameliorates Fibrosis in Experimental Crohn's Disease. |
Q36342122 | Activation of TRPV1 attenuates high salt-induced cardiac hypertrophy through improvement of mitochondrial function |
Q36137368 | Activation of transient receptor potential canonical 3 (TRPC3)-mediated Ca2+ entry by A1 adenosine receptor in cardiomyocytes disturbs atrioventricular conduction |
Q35895767 | Amelioration of glucolipotoxicity-induced endoplasmic reticulum stress by a "chemical chaperone" in human THP-1 monocytes |
Q35235668 | Angiotensin II contributes to podocyte injury by increasing TRPC6 expression via an NFAT-mediated positive feedback signaling pathway. |
Q42711522 | Antagonistic Regulation of Actin Dynamics and Cell Motility by TRPC5 and TRPC6 Channels |
Q37943290 | Balancing calcium signals through TRPC5 and TRPC6 in podocytes |
Q42425047 | Ca(2+) influx through L-type Ca(2+) channels and transient receptor potential channels activates pathological hypertrophy signaling |
Q52596353 | Ca2+ handling remodeling and STIM1L/Orai1/TRPC1/TRPC4 upregulation in monocrotaline-induced right ventricular hypertrophy. |
Q30493465 | Ca2+ influx and protein scaffolding via TRPC3 sustain PKCbeta and ERK activation in B cells |
Q42592376 | Calcium influx through Cav1.2 is a proximal signal for pathological cardiomyocyte hypertrophy |
Q42068754 | Calcium mediates glomerular filtration through calcineurin and mTORC2/Akt signaling |
Q27692627 | Calcium regulates podocyte actin dynamics |
Q35182794 | Calcium sensing receptor modulates extracellular calcium entry and proliferation via TRPC3/6 channels in cultured human mesangial cells |
Q37889811 | Calcium signaling dysfunction in heart disease |
Q34116745 | Canonical TRP channels and mechanotransduction: from physiology to disease states. |
Q39168875 | Canonical Transient Receptor Potential Channels and Their Link with Cardio/Cerebro-Vascular Diseases |
Q98613664 | Canonical Transient Receptor Potential Channels and Vascular Smooth Muscle Cell Plasticity |
Q28583151 | Canonical transient receptor potential 6 (TRPC6), a redox-regulated cation channel |
Q47812827 | Cardiac Remodeling and Disease: SOCE and TRPC Signaling in Cardiac Pathology |
Q34110454 | Cardiac overexpression of constitutively active Galpha q causes angiotensin II type1 receptor activation, leading to progressive heart failure and ventricular arrhythmias in transgenic mice |
Q39258979 | Cardiomyocyte Ca2+ homeostasis as a therapeutic target in heart failure with reduced and preserved ejection fraction. |
Q37953767 | Cardiomyocyte calcineurin signaling in subcellular domains: from the sarcolemma to the nucleus and beyond |
Q36479676 | Cardioprotection by Klotho through downregulation of TRPC6 channels in the mouse heart |
Q26853664 | Cell biology and pathology of podocytes |
Q37543708 | Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy |
Q41642227 | Could early ischemic arrhythmia triggered by purinergic activation of the transient receptor potential channels be prevented by creatine? |
Q36192690 | Critical role for stromal interaction molecule 1 in cardiac hypertrophy |
Q33636598 | Critical role of TRPC1-mediated Ca²⁺ entry in decidualization of human endometrial stromal cells |
Q33724430 | Cyclic GMP/PKG-dependent inhibition of TRPC6 channel activity and expression negatively regulates cardiomyocyte NFAT activation Novel mechanism of cardiac stress modulation by PDE5 inhibition |
Q36495935 | Cytoskeletal regulation of TRPC channels in the cardiorenal system. |
Q58707775 | Daikenchuto (Da-Jian-Zhong-Tang) ameliorates intestinal fibrosis by activating myofibroblast transient receptor potential ankyrin 1 channel |
Q38341513 | Danger- and pathogen-associated molecular patterns recognition by pattern-recognition receptors and ion channels of the transient receptor potential family triggers the inflammasome activation in immune cells and sensory neurons. |
Q57987856 | Defective diacylglycerol-induced Ca2+entry but normal agonist-induced activation responses in TRPC6-deficient mouse platelets |
Q37723488 | Deletion of TRPC6 Attenuates NMDA Receptor-Mediated Ca2+ Entry and Ca2+-Induced Neurotoxicity Following Cerebral Ischemia and Oxygen-Glucose Deprivation |
Q35865084 | Dietary Omega-3 Polyunsaturated Fatty Acids Suppress NHE-1 Upregulation in a Rabbit Model of Volume- and Pressure-Overload |
Q54465148 | Differential expression of TRPC channels in the left ventricle of spontaneously hypertensive rats. |
Q43142393 | Dynamics of receptor-operated Ca(2+) currents through TRPC channels controlled via the PI(4,5)P2-PLC signaling pathway |
Q35056963 | Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules |
Q92891530 | Effect of SKF‑96365 on cardiomyocyte hypertrophy induced by angiotensin II |
Q37190351 | Effects of thapsigargin and phenylephrine on calcineurin and protein kinase C signaling functions in cardiac myocytes |
Q37822590 | Emerging concepts for the role of TRP channels in the cardiovascular system |
Q52800433 | Enhanced transient receptor potential channel-mediated Ca2+ influx in the cells with phospholipase C-δ1 overexpression: its possible role in coronary artery spasm. |
Q42683699 | FK506 ameliorates podocyte injury in type 2 diabetic nephropathy by down-regulating TRPC6 and NFAT expression |
Q38588139 | From GTP and G proteins to TRPC channels: a personal account |
Q24297168 | Functional regulation of transient receptor potential canonical 7 by cGMP-dependent protein kinase Iα |
Q44963431 | Functional transient receptor potential canonical type 1 channels in human atrial myocytes |
Q36947844 | Gain-of-function mutations in transient receptor potential C6 (TRPC6) activate extracellular signal-regulated kinases 1/2 (ERK1/2) |
Q34835284 | Heterologous down-regulation of angiotensin type 1 receptors by purinergic P2Y2 receptor stimulation through S-nitrosylation of NF-kappaB. |
Q89964091 | High Glucose-Induced TRPC6 Channel Activation Decreases Glutamate Uptake in Rat Retinal Müller Cells |
Q37657529 | Hyperactive adverse mechanical stress responses in dystrophic heart are coupled to transient receptor potential canonical 6 and blocked by cGMP-protein kinase G modulation. |
Q93092881 | Hypertrophy of human embryonic stem cell-derived cardiomyocytes supported by positive feedback between Ca2+ and diacylglycerol signals |
Q41682169 | Induction of a novel cation current in cardiac ventricular myocytes by flufenamic acid and related drugs |
Q33997650 | Influence of p53 in the transition of myotrophin-induced cardiac hypertrophy to heart failure |
Q46436896 | Ins(1,4,5)P(3) regulates phospholipase Cbeta1 expression in cardiomyocytes |
Q46539324 | Integrated Omic Analysis of a Guinea Pig Model of Heart Failure and Sudden Cardiac Death. |
Q42846604 | Integration of phosphoinositide- and calmodulin-mediated regulation of TRPC6. |
Q38913484 | Intestinal myofibroblast TRPC6 channel may contribute to stenotic fibrosis in Crohn's disease |
Q89975502 | Light-Mediated Control over TRPC3-Mediated NFAT Signaling |
Q48258000 | Lipid signaling to membrane proteins: From second messengers to membrane domains and adapter-free endocytosis. |
Q53570369 | Losartan treating podocyte injury induced by Ang II via downregulation of TRPC6 in podocytes. |
Q37117338 | Loss of Mouse P2Y6 Nucleotide Receptor Is Associated with Physiological Macrocardia and Amplified Pathological Cardiac Hypertrophy. |
Q40205339 | Major contribution of the 3/6/7 class of TRPC channels to myocardial ischemia/reperfusion and cellular hypoxia/reoxygenation injuries |
Q63131766 | Mechanisms of physiological and pathological cardiac hypertrophy |
Q34789739 | Mechanosensitive channels in striated muscle and the cardiovascular system: not quite a stretch anymore. |
Q28580076 | Mild hypoxia-induced cardiomyocyte hypertrophy via up-regulation of HIF-1α-mediated TRPC signalling |
Q90221065 | Mitochondrial TRPC3 promotes cell proliferation by regulating the mitochondrial calcium and metabolism in renal polycystin-2 knockdown cells |
Q89964328 | Modulation of Calcium Transients in Cardiomyocytes by Transient Receptor Potential Canonical 6 Channels |
Q44823129 | Molecular changes in the early phase of renin-dependent cardiac hypertrophy in hypertensive cyp1a1ren-2 transgenic rats |
Q34575287 | Molecular determinants of cardiac fibroblast electrical function and therapeutic implications for atrial fibrillation. |
Q53243126 | Murine cardiac growth, TRPC channels, and cGMP kinase I. |
Q42428274 | Myocardin-related transcription factor A is a common mediator of mechanical stress- and neurohumoral stimulation-induced cardiac hypertrophic signaling leading to activation of brain natriuretic peptide gene expression |
Q46859563 | NADPH oxidase 2 mediates angiotensin II-dependent cellular arrhythmias via PKA and CaMKII. |
Q34534382 | Nicorandil prevents Gαq-induced progressive heart failure and ventricular arrhythmias in transgenic mice |
Q37917873 | Nitric oxide synthase and cyclic GMP signaling in cardiac myocytes: from contractility to remodeling |
Q34044364 | Novel insights into the mechanisms mediating the local antihypertrophic effects of cardiac atrial natriuretic peptide: role of cGMP-dependent protein kinase and RGS2. |
Q36812431 | Nuclear factor κB mediates suppression of canonical transient receptor potential 6 expression by reactive oxygen species and protein kinase C in kidney cells |
Q37075920 | Old dog, new tricks: novel cardiac targets and stress regulation by protein kinase G. |
Q92448823 | Orai1 Channel Inhibition Preserves Left Ventricular Systolic Function and Normal Ca2+ Handling After Pressure Overload |
Q37008361 | P2Y6 receptor-Galpha12/13 signalling in cardiomyocytes triggers pressure overload-induced cardiac fibrosis |
Q37417757 | PDE1C deficiency antagonizes pathological cardiac remodeling and dysfunction. |
Q35081644 | PKC-dependent coupling of calcium permeation through transient receptor potential canonical 3 (TRPC3) to calcineurin signaling in HL-1 myocytes |
Q37264382 | Pdx-1 activates islet α- and β-cell proliferation via a mechanism regulated by transient receptor potential cation channels 3 and 6 and extracellular signal-regulated kinases 1 and 2. |
Q33832734 | Pertussis toxin up-regulates angiotensin type 1 receptors through Toll-like receptor 4-mediated Rac activation. |
Q33764566 | Phosphodiesterase 5 inhibition ameliorates angiontensin II-induced podocyte dysmotility via the protein kinase G-mediated downregulation of TRPC6 activity |
Q33799926 | Phosphorylation of TRPC6 channels at Thr69 is required for anti-hypertrophic effects of phosphodiesterase 5 inhibition |
Q37072447 | Physiology and pathophysiology of canonical transient receptor potential channels |
Q92631461 | Post-Translational Modification and Natural Mutation of TRPC Channels |
Q46311217 | Proline-dependent and basophilic kinases phosphorylate human TRPC6 at serine 14 to control channel activity through increased membrane expression |
Q79714987 | Promotion of cardiac hypertrophy by TRPC-mediated calcium entry |
Q88959338 | Pyrazolo[1,5-a]pyrimidine TRPC6 antagonists for the treatment of gastric cancer |
Q40250028 | Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels |
Q39504774 | RNA interference targeting STIM1 suppresses vascular smooth muscle cell proliferation and neointima formation in the rat. |
Q37809599 | Regulation of Angiotensin II receptor signaling by cysteine modification of NF-κB |
Q37960090 | Regulation of cardiovascular TRP channel functions along the NO-cGMP-PKG axis |
Q42497705 | Resistance to pathologic cardiac hypertrophy and reduced expression of CaV1.2 in Trpc3-depleted mice |
Q37298485 | Role of BKbeta1 in Na+ reabsorption by cortical collecting ducts of Na+-deprived mice |
Q35035202 | Role of TRP channels in the cardiovascular system |
Q90221592 | Role of Transient Receptor Potential Canonical Channels in Heart Physiology and Pathophysiology |
Q37207026 | Roles of TRP channels in the development of cardiac hypertrophy |
Q34144673 | Roles of cGMP-dependent protein kinase I (cGKI) and PDE5 in the regulation of Ang II-induced cardiac hypertrophy and fibrosis. |
Q24296931 | S165F mutation of junctophilin 2 affects Ca2+ signalling in skeletal muscle |
Q24304302 | SNF8, a member of the ESCRT-II complex, interacts with TRPC6 and enhances its channel activity |
Q35637186 | STIM1-dependent store-operated Ca²⁺ entry is required for pathological cardiac hypertrophy |
Q37476541 | STIM1/Orai1-mediated SOCE: current perspectives and potential roles in cardiac function and pathology |
Q35886284 | Screening of Transient Receptor Potential Canonical Channel Activators Identifies Novel Neurotrophic Piperazine Compounds |
Q34963488 | Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound |
Q37432783 | Sensing pressure in the cardiovascular system: Gq-coupled mechanoreceptors and TRP channels. |
Q30501923 | Serine-threonine kinase with-no-lysine 4 (WNK4) controls blood pressure via transient receptor potential canonical 3 (TRPC3) in the vasculature |
Q37660726 | Significant contribution of TRPC6 channel-mediated Ca2+ influx to the pathogenesis of Crohn's disease fibrotic stenosis |
Q36887547 | Small-molecule therapies for cardiac hypertrophy: moving beneath the cell surface |
Q35158231 | Store-operated calcium entry and the localization of STIM1 and Orai1 proteins in isolated mouse sinoatrial node cells. |
Q46773101 | Stromal interaction molecule 1 haploinsufficiency causes maladaptive response to pressure overload |
Q90155507 | Structural basis for pharmacological modulation of the TRPC6 channel |
Q88488611 | Structure of the receptor-activated human TRPC6 and TRPC3 ion channels |
Q38111283 | TRP channels |
Q24624455 | TRP-ing up heart and vessels: canonical transient receptor potential channels and cardiovascular disease |
Q39309086 | TRPC Channel Downstream Signaling Cascades. |
Q89805562 | TRPC Channels in Cardiac Plasticity |
Q50999476 | TRPC Channels in Health and Disease. |
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Q92636542 | TRPC Channels: Dysregulation and Ca2+ Mishandling in Ischemic Heart Disease |
Q33859656 | TRPC channels are necessary mediators of pathologic cardiac hypertrophy |
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Q33896913 | TRPC1 channels are critical for hypertrophic signaling in the heart |
Q41313867 | TRPC3 Channels in Cardiac Fibrosis. |
Q64978028 | TRPC3 as a Target of Novel Therapeutic Interventions. |
Q52146538 | TRPC3 channel confers cerebrovascular remodelling during hypertension via transactivation of EGF receptor signalling. |
Q34460234 | TRPC3 contributes to regulation of cardiac contractility and arrhythmogenesis by dynamic interaction with NCX1. |
Q48005002 | TRPC3 participates in angiotensin II type 1 receptor-dependent stress-induced slow increase in intracellular Ca(2+) concentration in mouse cardiomyocytes |
Q30828286 | TRPC3 positively regulates reactive oxygen species driving maladaptive cardiac remodeling. |
Q28817018 | TRPC3-GEF-H1 axis mediates pressure overload-induced cardiac fibrosis |
Q41252402 | TRPC3-Nox2 complex mediates doxorubicin-induced myocardial atrophy. |
Q54976933 | TRPC5-eNOS Axis Negatively Regulates ATP-Induced Cardiomyocyte Hypertrophy. |
Q41308921 | TRPC6 counteracts TRPC3-Nox2 protein complex leading to attenuation of hyperglycemia-induced heart failure in mice |
Q34695410 | TRPC6 enhances angiotensin II-induced albuminuria |
Q37139035 | TRPC6 mutations associated with focal segmental glomerulosclerosis cause constitutive activation of NFAT-dependent transcription. |
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Q35613348 | The mutant Moonwalker TRPC3 channel links calcium signaling to lipid metabolism in the developing cerebellum |
Q38066188 | The other side of cardiac Ca(2+) signaling: transcriptional control |
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