TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy

scientific article

TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/SJ.EMBOJ.7601417
P932PMC publication ID1636614
P698PubMed publication ID17082763
P5875ResearchGate publication ID6713729

P2093author name stringHiroyuki Kobayashi
Yasuo Mori
Hideki Sumimoto
Hitoshi Kurose
Motohiro Nishida
Yoji Sato
Ryuji Inoue
Taku Nagao
Naoya Onohara
P2860cites workDirect activation of human TRPC6 and TRPC3 channels by diacylglycerolQ22001504
Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growthQ24309615
Subunit composition of mammalian transient receptor potential channels in living cellsQ24530559
A simplified system for generating recombinant adenovirusesQ24682328
NFAT signaling: choreographing the social lives of cellsQ28216151
Regulation of TRPC6 channel activity by tyrosine phosphorylationQ28242371
Canonical transient receptor potential channels promote cardiomyocyte hypertrophy through activation of calcineurin signalingQ28261648
A calcineurin-dependent transcriptional pathway for cardiac hypertrophyQ28269300
Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophyQ28343890
Differential regulation of transient receptor potential melastatin 6 and 7 cation channels by ANG II in vascular smooth muscle cells from spontaneously hypertensive ratsQ28569103
Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitroQ28570955
G alpha(i) and G alpha(o) are target proteins of reactive oxygen speciesQ28574404
Galpha(12/13) mediates alpha(1)-adrenergic receptor-induced cardiac hypertrophyQ28611521
TRP channels as cellular sensorsQ29615917
Differential activation of transcription factors induced by Ca2+ response amplitude and durationQ29619010
The transient receptor potential protein homologue TRP6 is the essential component of vascular alpha(1)-adrenoceptor-activated Ca(2+)-permeable cation channelQ30979449
Signaling to the nucleus by an L-type calcium channel-calmodulin complex through the MAP kinase pathwayQ34094970
Cytoplasmic signaling pathways that regulate cardiac hypertrophyQ34142151
A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosisQ34416768
Receptor-operated Ca2(+)-permeable nonselective cation channels in vascular smooth muscle: a physiologic perspectiveQ34657139
Excitation-transcription coupling: signaling by ion channels to the nucleusQ35049919
Calcium-calcineurin signaling in the regulation of cardiac hypertrophyQ35874296
Ins(1,4,5)P3 receptors and inositol phosphates in the heart-evolutionary artefacts or active signal transducers?Q36134444
Inositol 1,4,5-trisphosphate receptor expression in cardiac myocytesQ36233054
Amplification of receptor signalling by Ca2+ entry-mediated translocation and activation of PLCgamma2 in B lymphocytes.Q36245720
Sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA) gene silencing and remodeling of the Ca2+ signaling mechanism in cardiac myocytesQ37621106
NFAT functions as a working memory of Ca2+ signals in decoding Ca2+ oscillationQ39804742
Heteromultimeric TRPC6-TRPC7 channels contribute to arginine vasopressin-induced cation current of A7r5 vascular smooth muscle cellsQ40280966
Multiple regulation by calcium of murine homologues of transient receptor potential proteins TRPC6 and TRPC7 expressed in HEK293 cellsQ40484838
A novel recombinant hyperaffinity inositol 1,4,5-trisphosphate (IP(3)) absorbent traps IP(3), resulting in specific inhibition of IP(3)-mediated calcium signalingQ40763852
Rapid shuttling of NF-AT in discrimination of Ca2+ signals and immunosuppressionQ41157105
The effects of modulation of calcium influx through the voltage-sensitive calcium channel on cardiomyocyte hypertrophyQ41674521
Transient receptor potential melastatin 7 ion channels regulate magnesium homeostasis in vascular smooth muscle cells: role of angiotensin II.Q42471701
Pharmacological activation of plasma-membrane KATP channels reduces reoxygenation-induced Ca(2+) overload in cardiac myocytes via modulation of the diastolic membrane potentialQ43263045
Capacitative calcium entry contributes to nuclear factor of activated T-cells nuclear translocation and hypertrophy in cardiomyocytesQ43876941
Signaling microdomains define the specificity of receptor-mediated InsP(3) pathways in neuronsQ43968738
Activation of the Ca(2+)-activated nonselective cation channel by diacylglycerol analogues in rat cardiomyocytesQ44805004
TRPC3 mediates pyrimidine receptor-induced depolarization of cerebral arteriesQ45190188
Amlodipine ameliorates myocardial hypertrophy by inhibiting EGFR phosphorylationQ45225661
G alpha 12/13- and reactive oxygen species-dependent activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase by angiotensin receptor stimulation in rat neonatal cardiomyocytes.Q45295556
Increased 1,4-dihydropyridine binding sites in serum-stimulated cardiomyocyte hypertrophy.Q46170063
Galpha12/13-mediated production of reactive oxygen species is critical for angiotensin receptor-induced NFAT activation in cardiac fibroblasts.Q46435005
Role of endogenous TRPC6 channels in Ca2+ signal generation in A7r5 smooth muscle cells.Q46735379
Voltage-dependent calcium influx in human sperm assessed by simultaneous optical detection of intracellular calcium and membrane potentialQ47891172
Intracardiac detection of angiotensinogen and renin: a localized renin-angiotensin system in neonatal rat heartQ67567248
Differential requirement of G alpha12, G alpha13, G alphaq, and G beta gamma for endothelin-1-induced c-Jun NH2-terminal kinase and extracellular signal-regulated kinase activationQ73049257
Transient receptor potential channels regulate myogenic tone of resistance arteriesQ77678843
Dexamethasone-induced hypertrophy in rat neonatal cardiac myocytes involves an elevated L-type Ca(2+)currentQ78050100
P433issue22
P407language of work or nameEnglishQ1860
P304page(s)5305-5316
P577publication date2006-11-02
P1433published inThe EMBO JournalQ1278554
P1476titleTRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy
P478volume25

Reverse relations

cites work (P2860)
Q26781720"TRP inflammation" relationship in cardiovascular system
Q91637779A TR(i)P to Cell Migration: New Roles of TRP Channels in Mechanotransduction and Cancer
Q35546884A cardiac pathway of cyclic GMP-independent signaling of guanylyl cyclase A, the receptor for atrial natriuretic peptide
Q46611820A novel signaling pathway of ADP-ribosyl cyclase activation by angiotensin II in adult rat cardiomyocytes
Q30492499A pathogenic C terminus-truncated polycystin-2 mutant enhances receptor-activated Ca2+ entry via association with TRPC3 and TRPC7
Q38173671A pathway and network review on beta-adrenoceptor signaling and beta blockers in cardiac remodeling
Q42436589ATP/UTP activate cation-permeable channels with TRPC3/7 properties in rat cardiomyocytes.
Q39743095Accelerated development of pressure overload-induced cardiac hypertrophy and dysfunction in an RyR2-R176Q knockin mouse model
Q52430882Activation of Myofibroblast TRPA1 by Steroids and Pirfenidone Ameliorates Fibrosis in Experimental Crohn's Disease.
Q36342122Activation of TRPV1 attenuates high salt-induced cardiac hypertrophy through improvement of mitochondrial function
Q36137368Activation of transient receptor potential canonical 3 (TRPC3)-mediated Ca2+ entry by A1 adenosine receptor in cardiomyocytes disturbs atrioventricular conduction
Q35895767Amelioration of glucolipotoxicity-induced endoplasmic reticulum stress by a "chemical chaperone" in human THP-1 monocytes
Q35235668Angiotensin II contributes to podocyte injury by increasing TRPC6 expression via an NFAT-mediated positive feedback signaling pathway.
Q42711522Antagonistic Regulation of Actin Dynamics and Cell Motility by TRPC5 and TRPC6 Channels
Q37943290Balancing calcium signals through TRPC5 and TRPC6 in podocytes
Q42425047Ca(2+) influx through L-type Ca(2+) channels and transient receptor potential channels activates pathological hypertrophy signaling
Q52596353Ca2+ handling remodeling and STIM1L/Orai1/TRPC1/TRPC4 upregulation in monocrotaline-induced right ventricular hypertrophy.
Q30493465Ca2+ influx and protein scaffolding via TRPC3 sustain PKCbeta and ERK activation in B cells
Q42592376Calcium influx through Cav1.2 is a proximal signal for pathological cardiomyocyte hypertrophy
Q42068754Calcium mediates glomerular filtration through calcineurin and mTORC2/Akt signaling
Q27692627Calcium regulates podocyte actin dynamics
Q35182794Calcium sensing receptor modulates extracellular calcium entry and proliferation via TRPC3/6 channels in cultured human mesangial cells
Q37889811Calcium signaling dysfunction in heart disease
Q34116745Canonical TRP channels and mechanotransduction: from physiology to disease states.
Q39168875Canonical Transient Receptor Potential Channels and Their Link with Cardio/Cerebro-Vascular Diseases
Q98613664Canonical Transient Receptor Potential Channels and Vascular Smooth Muscle Cell Plasticity
Q28583151Canonical transient receptor potential 6 (TRPC6), a redox-regulated cation channel
Q47812827Cardiac Remodeling and Disease: SOCE and TRPC Signaling in Cardiac Pathology
Q34110454Cardiac overexpression of constitutively active Galpha q causes angiotensin II type1 receptor activation, leading to progressive heart failure and ventricular arrhythmias in transgenic mice
Q39258979Cardiomyocyte Ca2+ homeostasis as a therapeutic target in heart failure with reduced and preserved ejection fraction.
Q37953767Cardiomyocyte calcineurin signaling in subcellular domains: from the sarcolemma to the nucleus and beyond
Q36479676Cardioprotection by Klotho through downregulation of TRPC6 channels in the mouse heart
Q26853664Cell biology and pathology of podocytes
Q37543708Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy
Q41642227Could early ischemic arrhythmia triggered by purinergic activation of the transient receptor potential channels be prevented by creatine?
Q36192690Critical role for stromal interaction molecule 1 in cardiac hypertrophy
Q33636598Critical role of TRPC1-mediated Ca²⁺ entry in decidualization of human endometrial stromal cells
Q33724430Cyclic GMP/PKG-dependent inhibition of TRPC6 channel activity and expression negatively regulates cardiomyocyte NFAT activation Novel mechanism of cardiac stress modulation by PDE5 inhibition
Q36495935Cytoskeletal regulation of TRPC channels in the cardiorenal system.
Q58707775Daikenchuto (Da-Jian-Zhong-Tang) ameliorates intestinal fibrosis by activating myofibroblast transient receptor potential ankyrin 1 channel
Q38341513Danger- and pathogen-associated molecular patterns recognition by pattern-recognition receptors and ion channels of the transient receptor potential family triggers the inflammasome activation in immune cells and sensory neurons.
Q57987856Defective diacylglycerol-induced Ca2+entry but normal agonist-induced activation responses in TRPC6-deficient mouse platelets
Q37723488Deletion of TRPC6 Attenuates NMDA Receptor-Mediated Ca2+ Entry and Ca2+-Induced Neurotoxicity Following Cerebral Ischemia and Oxygen-Glucose Deprivation
Q35865084Dietary Omega-3 Polyunsaturated Fatty Acids Suppress NHE-1 Upregulation in a Rabbit Model of Volume- and Pressure-Overload
Q54465148Differential expression of TRPC channels in the left ventricle of spontaneously hypertensive rats.
Q43142393Dynamics of receptor-operated Ca(2+) currents through TRPC channels controlled via the PI(4,5)P2-PLC signaling pathway
Q35056963Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules
Q92891530Effect of SKF‑96365 on cardiomyocyte hypertrophy induced by angiotensin II
Q37190351Effects of thapsigargin and phenylephrine on calcineurin and protein kinase C signaling functions in cardiac myocytes
Q37822590Emerging concepts for the role of TRP channels in the cardiovascular system
Q52800433Enhanced transient receptor potential channel-mediated Ca2+ influx in the cells with phospholipase C-δ1 overexpression: its possible role in coronary artery spasm.
Q42683699FK506 ameliorates podocyte injury in type 2 diabetic nephropathy by down-regulating TRPC6 and NFAT expression
Q38588139From GTP and G proteins to TRPC channels: a personal account
Q24297168Functional regulation of transient receptor potential canonical 7 by cGMP-dependent protein kinase Iα
Q44963431Functional transient receptor potential canonical type 1 channels in human atrial myocytes
Q36947844Gain-of-function mutations in transient receptor potential C6 (TRPC6) activate extracellular signal-regulated kinases 1/2 (ERK1/2)
Q34835284Heterologous down-regulation of angiotensin type 1 receptors by purinergic P2Y2 receptor stimulation through S-nitrosylation of NF-kappaB.
Q89964091High Glucose-Induced TRPC6 Channel Activation Decreases Glutamate Uptake in Rat Retinal Müller Cells
Q37657529Hyperactive adverse mechanical stress responses in dystrophic heart are coupled to transient receptor potential canonical 6 and blocked by cGMP-protein kinase G modulation.
Q93092881Hypertrophy of human embryonic stem cell-derived cardiomyocytes supported by positive feedback between Ca2+ and diacylglycerol signals
Q41682169Induction of a novel cation current in cardiac ventricular myocytes by flufenamic acid and related drugs
Q33997650Influence of p53 in the transition of myotrophin-induced cardiac hypertrophy to heart failure
Q46436896Ins(1,4,5)P(3) regulates phospholipase Cbeta1 expression in cardiomyocytes
Q46539324Integrated Omic Analysis of a Guinea Pig Model of Heart Failure and Sudden Cardiac Death.
Q42846604Integration of phosphoinositide- and calmodulin-mediated regulation of TRPC6.
Q38913484Intestinal myofibroblast TRPC6 channel may contribute to stenotic fibrosis in Crohn's disease
Q89975502Light-Mediated Control over TRPC3-Mediated NFAT Signaling
Q48258000Lipid signaling to membrane proteins: From second messengers to membrane domains and adapter-free endocytosis.
Q53570369Losartan treating podocyte injury induced by Ang II via downregulation of TRPC6 in podocytes.
Q37117338Loss of Mouse P2Y6 Nucleotide Receptor Is Associated with Physiological Macrocardia and Amplified Pathological Cardiac Hypertrophy.
Q40205339Major contribution of the 3/6/7 class of TRPC channels to myocardial ischemia/reperfusion and cellular hypoxia/reoxygenation injuries
Q63131766Mechanisms of physiological and pathological cardiac hypertrophy
Q34789739Mechanosensitive channels in striated muscle and the cardiovascular system: not quite a stretch anymore.
Q28580076Mild hypoxia-induced cardiomyocyte hypertrophy via up-regulation of HIF-1α-mediated TRPC signalling
Q90221065Mitochondrial TRPC3 promotes cell proliferation by regulating the mitochondrial calcium and metabolism in renal polycystin-2 knockdown cells
Q89964328Modulation of Calcium Transients in Cardiomyocytes by Transient Receptor Potential Canonical 6 Channels
Q44823129Molecular changes in the early phase of renin-dependent cardiac hypertrophy in hypertensive cyp1a1ren-2 transgenic rats
Q34575287Molecular determinants of cardiac fibroblast electrical function and therapeutic implications for atrial fibrillation.
Q53243126Murine cardiac growth, TRPC channels, and cGMP kinase I.
Q42428274Myocardin-related transcription factor A is a common mediator of mechanical stress- and neurohumoral stimulation-induced cardiac hypertrophic signaling leading to activation of brain natriuretic peptide gene expression
Q46859563NADPH oxidase 2 mediates angiotensin II-dependent cellular arrhythmias via PKA and CaMKII.
Q34534382Nicorandil prevents Gαq-induced progressive heart failure and ventricular arrhythmias in transgenic mice
Q37917873Nitric oxide synthase and cyclic GMP signaling in cardiac myocytes: from contractility to remodeling
Q34044364Novel insights into the mechanisms mediating the local antihypertrophic effects of cardiac atrial natriuretic peptide: role of cGMP-dependent protein kinase and RGS2.
Q36812431Nuclear factor κB mediates suppression of canonical transient receptor potential 6 expression by reactive oxygen species and protein kinase C in kidney cells
Q37075920Old dog, new tricks: novel cardiac targets and stress regulation by protein kinase G.
Q92448823Orai1 Channel Inhibition Preserves Left Ventricular Systolic Function and Normal Ca2+ Handling After Pressure Overload
Q37008361P2Y6 receptor-Galpha12/13 signalling in cardiomyocytes triggers pressure overload-induced cardiac fibrosis
Q37417757PDE1C deficiency antagonizes pathological cardiac remodeling and dysfunction.
Q35081644PKC-dependent coupling of calcium permeation through transient receptor potential canonical 3 (TRPC3) to calcineurin signaling in HL-1 myocytes
Q37264382Pdx-1 activates islet α- and β-cell proliferation via a mechanism regulated by transient receptor potential cation channels 3 and 6 and extracellular signal-regulated kinases 1 and 2.
Q33832734Pertussis toxin up-regulates angiotensin type 1 receptors through Toll-like receptor 4-mediated Rac activation.
Q33764566Phosphodiesterase 5 inhibition ameliorates angiontensin II-induced podocyte dysmotility via the protein kinase G-mediated downregulation of TRPC6 activity
Q33799926Phosphorylation of TRPC6 channels at Thr69 is required for anti-hypertrophic effects of phosphodiesterase 5 inhibition
Q37072447Physiology and pathophysiology of canonical transient receptor potential channels
Q92631461Post-Translational Modification and Natural Mutation of TRPC Channels
Q46311217Proline-dependent and basophilic kinases phosphorylate human TRPC6 at serine 14 to control channel activity through increased membrane expression
Q79714987Promotion of cardiac hypertrophy by TRPC-mediated calcium entry
Q88959338Pyrazolo[1,5-a]pyrimidine TRPC6 antagonists for the treatment of gastric cancer
Q40250028Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels
Q39504774RNA interference targeting STIM1 suppresses vascular smooth muscle cell proliferation and neointima formation in the rat.
Q37809599Regulation of Angiotensin II receptor signaling by cysteine modification of NF-κB
Q37960090Regulation of cardiovascular TRP channel functions along the NO-cGMP-PKG axis
Q42497705Resistance to pathologic cardiac hypertrophy and reduced expression of CaV1.2 in Trpc3-depleted mice
Q37298485Role of BKbeta1 in Na+ reabsorption by cortical collecting ducts of Na+-deprived mice
Q35035202Role of TRP channels in the cardiovascular system
Q90221592Role of Transient Receptor Potential Canonical Channels in Heart Physiology and Pathophysiology
Q37207026Roles of TRP channels in the development of cardiac hypertrophy
Q34144673Roles of cGMP-dependent protein kinase I (cGKI) and PDE5 in the regulation of Ang II-induced cardiac hypertrophy and fibrosis.
Q24296931S165F mutation of junctophilin 2 affects Ca2+ signalling in skeletal muscle
Q24304302SNF8, a member of the ESCRT-II complex, interacts with TRPC6 and enhances its channel activity
Q35637186STIM1-dependent store-operated Ca²⁺ entry is required for pathological cardiac hypertrophy
Q37476541STIM1/Orai1-mediated SOCE: current perspectives and potential roles in cardiac function and pathology
Q35886284Screening of Transient Receptor Potential Canonical Channel Activators Identifies Novel Neurotrophic Piperazine Compounds
Q34963488Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound
Q37432783Sensing pressure in the cardiovascular system: Gq-coupled mechanoreceptors and TRP channels.
Q30501923Serine-threonine kinase with-no-lysine 4 (WNK4) controls blood pressure via transient receptor potential canonical 3 (TRPC3) in the vasculature
Q37660726Significant contribution of TRPC6 channel-mediated Ca2+ influx to the pathogenesis of Crohn's disease fibrotic stenosis
Q36887547Small-molecule therapies for cardiac hypertrophy: moving beneath the cell surface
Q35158231Store-operated calcium entry and the localization of STIM1 and Orai1 proteins in isolated mouse sinoatrial node cells.
Q46773101Stromal interaction molecule 1 haploinsufficiency causes maladaptive response to pressure overload
Q90155507Structural basis for pharmacological modulation of the TRPC6 channel
Q88488611Structure of the receptor-activated human TRPC6 and TRPC3 ion channels
Q38111283TRP channels
Q24624455TRP-ing up heart and vessels: canonical transient receptor potential channels and cardiovascular disease
Q39309086TRPC Channel Downstream Signaling Cascades.
Q89805562TRPC Channels in Cardiac Plasticity
Q50999476TRPC Channels in Health and Disease.
Q92257319TRPC Channels in Proteinuric Kidney Diseases
Q92636542TRPC Channels: Dysregulation and Ca2+ Mishandling in Ischemic Heart Disease
Q33859656TRPC channels are necessary mediators of pathologic cardiac hypertrophy
Q57295776TRPC channels in exercise-mimetic therapy
Q33896913TRPC1 channels are critical for hypertrophic signaling in the heart
Q41313867TRPC3 Channels in Cardiac Fibrosis.
Q64978028TRPC3 as a Target of Novel Therapeutic Interventions.
Q52146538TRPC3 channel confers cerebrovascular remodelling during hypertension via transactivation of EGF receptor signalling.
Q34460234TRPC3 contributes to regulation of cardiac contractility and arrhythmogenesis by dynamic interaction with NCX1.
Q48005002TRPC3 participates in angiotensin II type 1 receptor-dependent stress-induced slow increase in intracellular Ca(2+) concentration in mouse cardiomyocytes
Q30828286TRPC3 positively regulates reactive oxygen species driving maladaptive cardiac remodeling.
Q28817018TRPC3-GEF-H1 axis mediates pressure overload-induced cardiac fibrosis
Q41252402TRPC3-Nox2 complex mediates doxorubicin-induced myocardial atrophy.
Q54976933TRPC5-eNOS Axis Negatively Regulates ATP-Induced Cardiomyocyte Hypertrophy.
Q41308921TRPC6 counteracts TRPC3-Nox2 protein complex leading to attenuation of hyperglycemia-induced heart failure in mice
Q34695410TRPC6 enhances angiotensin II-induced albuminuria
Q37139035TRPC6 mutations associated with focal segmental glomerulosclerosis cause constitutive activation of NFAT-dependent transcription.
Q37089726Tackling heart failure in the twenty-first century
Q35686998The Ca(2+)-activated cation channel TRPM4 is a negative regulator of angiotensin II-induced cardiac hypertrophy
Q37375441The NO/ONOO-cycle as the central cause of heart failure
Q38222953The TRPC family of TRP channels: roles inferred (mostly) from knockout mice and relationship to ORAI proteins
Q48209998The TRPM4 channel is functionally important for the beneficial cardiac remodeling induced by endurance training
Q35215931The involvement of TRPC3 channels in sinoatrial arrhythmias
Q35613348The mutant Moonwalker TRPC3 channel links calcium signaling to lipid metabolism in the developing cerebellum
Q38066188The other side of cardiac Ca(2+) signaling: transcriptional control
Q35182923The transient receptor potential (TRP) channel TRPC3 TRP domain and AMP-activated protein kinase binding site are required for TRPC3 activation by erythropoietin
Q36873848The zebrafish as a novel animal model to study the molecular mechanisms of mechano-electrical feedback in the heart
Q34969926Three 4-letter words of hypertension-related cardiac hypertrophy: TRPC, mTOR, and HDAC.
Q37065951Transient Receptor Potential Canonical (TRPC)/Orai1-dependent Store-operated Ca2+ Channels: NEW TARGETS OF ALDOSTERONE IN CARDIOMYOCYTES.
Q57461285Transient Receptor Potential Canonical 3 and Nuclear Factor of Activated T-cells C3 Signaling Pathway Critically Regulates Myocardial Fibrosis
Q24625500Transient receptor potential (TRP) channels and cardiac fibrosis
Q33562143Transient receptor potential (TRP) channels: a clinical perspective
Q36909069Transient receptor potential canonical-3 channel-dependent fibroblast regulation in atrial fibrillation
Q28244558Transient receptor potential channels as therapeutic targets
Q34111821Transient receptor potential channels contribute to pathological structural and functional remodeling after myocardial infarction
Q91142459Transient receptor potential channels in cardiac health and disease
Q37398665Transient receptor potential: a large family of new channels of which several are involved in cardiac arrhythmia
Q33295387TrpC3 regulates hypertrophy-associated gene expression without affecting myocyte beating or cell size
Q35613275Trpc2 depletion protects red blood cells from oxidative stress-induced hemolysis
Q36585593Tumor suppressor cylindromatosis acts as a negative regulator for Streptococcus pneumoniae-induced NFAT signaling
Q42133639Tyrosine phosphorylation-dependent activation of TRPC6 regulated by PLC-γ1 and nephrin: effect of mutations associated with focal segmental glomerulosclerosis
Q92220029Upregulation of Transient Receptor Potential Canonical Type 3 Channel via AT1R/TGF-β1/Smad2/3 Induces Atrial Fibrosis in Aging and Spontaneously Hypertensive Rats
Q92941380Very Low-Density Lipoproteins of Metabolic Syndrome Modulates STIM1, Suppresses Store-Operated Calcium Entry, and Deranges Myofilament Proteins in Atrial Myocytes
Q85845784Wnt/β-catenin signalling pathway mediates high glucose induced cell injury through activation of TRPC6 in podocytes

Search more.