scholarly article | Q13442814 |
P50 | author | Margaret A. Pericak-Vance | Q28554103 |
Jeffery M. Vance | Q30362072 | ||
Paul B. Rosenberg | Q37840662 | ||
P2093 | author name string | James L Burchette | |
David N Howell | |||
Michelle P Winn | |||
Peter J Conlon | |||
Shu Ying Kwan | |||
Seth Ebersviller | |||
Nikki Daskalakis | |||
Kelvin L Lynn | |||
April F Hawkins | |||
Tony Creazzo | |||
Merry Kay Farrington | |||
P433 | issue | 5729 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | focal segmental glomerulosclerosis | Q1435223 |
P304 | page(s) | 1801-1804 | |
P577 | publication date | 2005-05-05 | |
P1433 | published in | Science | Q192864 |
P1476 | title | A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis | |
P478 | volume | 308 |
Q37080814 | "Treasure your exceptions": recent advances in molecular genetics of glomerular disease |
Q91692922 | -254C>G SNP in the TRPC6 Gene Promoter Influences Its Expression via Interaction with the NF-κB Subunit RELA in Steroid-Resistant Nephrotic Syndrome Children |
Q37218316 | 20-Hydroxyeicosatetraenoic Acid (20-HETE) Modulates Canonical Transient Receptor Potential-6 (TRPC6) Channels in Podocytes |
Q46324243 | 254C>G: a TRPC6 promoter variation associated with enhanced transcription and steroid-resistant nephrotic syndrome in Chinese children |
Q51742235 | A (+)-larixol congener with high affinity and subtype selectivity towards TRPC6. |
Q51151673 | A Drosophila model system to assess the function of human monogenic podocyte mutations that cause nephrotic syndrome. |
Q88792365 | A NOX4/TRPC6 Pathway in Podocyte Calcium Regulation and Renal Damage in Diabetic Kidney Disease |
Q38218852 | A brief overview on IRM function across evolution. |
Q35133928 | A common mechanism underlies stretch activation and receptor activation of TRPC6 channels |
Q33676320 | A disease-causing mutation illuminates the protein membrane topology of the kidney-expressed prohibitin homology (PHB) domain protein podocin |
Q43060960 | A drug target for focal segmental glomerulosclerosis |
Q79751186 | A familial childhood-onset relapsing nephrotic syndrome |
Q39589119 | A flexible, multilayered protein scaffold maintains the slit in between glomerular podocytes |
Q30665384 | A high-powered view of the filtration barrier |
Q46945275 | A meta-analysis of expression signatures in glomerular disease |
Q51063406 | A molecular genetic analysis of childhood nephrotic syndrome in a cohort of Saudi Arabian families. |
Q46647791 | A mutation in TRPC6 channels abolishes their activation by hypoosmotic stretch but does not affect activation by diacylglycerol or G protein signaling cascades |
Q81913779 | A new TRP to kidney disease |
Q34124184 | A new locus for familial FSGS on chromosome 2p |
Q79390375 | A new piece in the nephrotic puzzle |
Q34714573 | A novel TRPC6 mutation in a family with podocytopathy and clinical variability. |
Q30913201 | A novel TRPC6 mutation that causes childhood FSGS. |
Q35228497 | A novel missense mutation of Wilms' Tumor 1 causes autosomal dominant FSGS. |
Q43349330 | A novel mutation, outside of the candidate region for diagnosis, in the inverted formin 2 gene can cause focal segmental glomerulosclerosis |
Q37280842 | A patient with nephrotic-range proteinuria and focal global glomerulosclerosis |
Q34402058 | A risk allele for focal segmental glomerulosclerosis in African Americans is located within a region containing APOL1 and MYH9 |
Q36618592 | A role for genetic susceptibility in sporadic focal segmental glomerulosclerosis |
Q83066084 | A self-limiting regulation of vasoconstrictor-activated TRPC3/C6/C7 channels coupled to PI(4,5)P₂-diacylglycerol signalling |
Q42004927 | ADCK4 "reenergizes" nephrotic syndrome |
Q39022403 | ATP acting through P2Y receptors causes activation of podocyte TRPC6 channels: role of podocin and reactive oxygen species |
Q52605522 | ATRA attenuate proteinuria via downregulation of TRPC6 in glomerulosclerosis rats induced by adriamycin. |
Q28579847 | Actin -related protein 3 (Arp3) is mutated in proteinuric BUF/Mna rats |
Q33991246 | Actin-depolymerizing factor cofilin-1 is necessary in maintaining mature podocyte architecture |
Q34455455 | Activation of NFAT signaling in podocytes causes glomerulosclerosis |
Q35636196 | Acute ethanol induces apoptosis by stimulating TRPC6 via elevation of superoxide in oxygenated podocytes |
Q36839516 | Advances in genetic diseases of the kidney: impact on renal medicine |
Q35056271 | Advances in the biology and genetics of the podocytopathies: implications for diagnosis and therapy |
Q24602407 | African ancestry allelic variation at the MYH9 gene contributes to increased susceptibility to non-diabetic end-stage kidney disease in Hispanic Americans |
Q36976648 | Altered functional properties of a TRPM2 variant in Guamanian ALS and PD. |
Q89754455 | Altered renal hemodynamics is associated with glomerular lipid accumulation in obese Dahl salt-sensitive leptin receptor mutant rats |
Q57794745 | Amplification of the Melanocortin-1 Receptor in Nephrotic Syndrome Identifies a Target for Podocyte Cytoskeleton Stabilization |
Q54451931 | Analysis of recessive CD2AP and ACTN4 mutations in steroid-resistant nephrotic syndrome. |
Q34608045 | AngII-induced glomerular mesangial cell proliferation inhibited by losartan via changes in intracellular calcium ion concentration |
Q35235668 | Angiotensin II contributes to podocyte injury by increasing TRPC6 expression via an NFAT-mediated positive feedback signaling pathway. |
Q30586651 | Angiotensin II has acute effects on TRPC6 channels in podocytes of freshly isolated glomeruli |
Q64277796 | Angiotensin II-mediated MYH9 downregulation causes structural and functional podocyte injury in diabetic kidney disease |
Q37860148 | Anion exchanger 1 in red blood cells and kidney: Band 3's in a pod. |
Q34455334 | Anion exchanger 1 interacts with nephrin in podocytes |
Q42711522 | Antagonistic Regulation of Actin Dynamics and Cell Motility by TRPC5 and TRPC6 Channels |
Q28504659 | Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis |
Q79759857 | Association of steroid and cyclosporin resistance in focal segmental glomerulosclerosis |
Q57048910 | Autosomal dominant PKD gets an atomic map |
Q37943290 | Balancing calcium signals through TRPC5 and TRPC6 in podocytes |
Q40289564 | Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodin |
Q33605113 | Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease |
Q91771277 | Bronchiectasis and Focal Segmental Glomerulosclerosis in Rheumatoid Arthritis |
Q54233125 | CD2-associated protein participates in podocyte apoptosis via PI3K/Akt signaling pathway. |
Q50987471 | CD2AP is associated with end-stage renal disease in patients with type 1 diabetes. |
Q50353233 | COL4A3 mutations cause focal segmental glomerulosclerosis |
Q24297952 | COL4A3/COL4A4 mutations producing focal segmental glomerulosclerosis and renal failure in thin basement membrane nephropathy |
Q24606103 | COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness |
Q42068754 | Calcium mediates glomerular filtration through calcineurin and mTORC2/Akt signaling |
Q27692627 | Calcium regulates podocyte actin dynamics |
Q26778579 | Calcium, TRPC channels, and regulation of the actin cytoskeleton in podocytes: towards a future of targeted therapies |
Q37072422 | Calcium-permeable ion channels in the kidney |
Q34116745 | Canonical TRP channels and mechanotransduction: from physiology to disease states. |
Q38758929 | Canonical Transient Receptor Potential 6 Channel: A New Target of Reactive Oxygen Species in Renal Physiology and Pathology |
Q39168875 | Canonical Transient Receptor Potential Channels and Their Link with Cardio/Cerebro-Vascular Diseases |
Q37104933 | Canonical transient receptor potential channel (TRPC)3 and TRPC6 associate with large-conductance Ca2+-activated K+ (BKCa) channels: role in BKCa trafficking to the surface of cultured podocytes |
Q36479676 | Cardioprotection by Klotho through downregulation of TRPC6 channels in the mouse heart |
Q42246930 | Case Report: Making a diagnosis of familial renal disease - clinical and patient perspectives |
Q26853664 | Cell biology and pathology of podocytes |
Q91558701 | Cerebral ischemia induces TRPC6 via HIF1α/ZEB2 axis in the glomerular podocytes and contributes to proteinuria |
Q38718670 | Changes in podocyte TRPC channels evoked by plasma and sera from patients with recurrent FSGS and by putative glomerular permeability factors |
Q37382555 | Channelopathies of transepithelial transport and vesicular function |
Q92109722 | Chondroitin sulfate degradation and eicosanoid metabolism pathways are impaired in focal segmental glomerulosclerosis: Experimental confirmation of an in silico prediction |
Q36667220 | Chromogranin A polymorphisms are associated with hypertensive renal disease. |
Q41022459 | Clinical Significance of IgM and C3 Glomerular Deposition in Primary Focal Segmental Glomerulosclerosis |
Q43501079 | Clinical and epidemiological assessment of steroid-resistant nephrotic syndrome associated with the NPHS2 R229Q variant |
Q54985317 | Clinical and pathological phenotype of genetic causes of focal segmental glomerulosclerosis in adults. |
Q36577165 | Clinical impact of research on the podocyte slit diaphragm |
Q42726858 | Clinical utility of genetic testing in children and adults with steroid-resistant nephrotic syndrome |
Q34639646 | Clinical value of NPHS2 analysis in early- and adult-onset steroid-resistant nephrotic syndrome. |
Q35952630 | Coinheritance of COL4A5 and MYO1E mutations accentuate the severity of kidney disease |
Q35698969 | Crk1/2-dependent signaling is necessary for podocyte foot process spreading in mouse models of glomerular disease |
Q88645885 | Cryo-EM structure of the cytoplasmic domain of murine transient receptor potential cation channel subfamily C member 6 (TRPC6) |
Q33724430 | Cyclic GMP/PKG-dependent inhibition of TRPC6 channel activity and expression negatively regulates cardiomyocyte NFAT activation Novel mechanism of cardiac stress modulation by PDE5 inhibition |
Q36495935 | Cytoskeletal regulation of TRPC channels in the cardiorenal system. |
Q33407312 | DGKE and atypical HUS. |
Q38586603 | Decade in review--glomerular disease: The glomerulus reveals some secrets |
Q47220708 | Deletion of diacylglycerol-responsive TRPC genes attenuates diabetic nephropathy by inhibiting activation of the TGFβ1 signaling pathway |
Q41974986 | Dexamethasone Resisted Podocyte Injury via Stabilizing TRPC6 Expression and Distribution |
Q35595863 | Discovery and pharmacological characterization of a novel potent inhibitor of diacylglycerol-sensitive TRPC cation channels |
Q92998664 | Discovery of endoplasmic reticulum calcium stabilizers to rescue ER-stressed podocytes in nephrotic syndrome |
Q39364606 | Disease modeling in genetic kidney diseases: mice. |
Q39194990 | Disease modeling in genetic kidney diseases: zebrafish |
Q42730836 | Disease-causing mutations of RhoGDIα induce Rac1 hyperactivation in podocytes |
Q24309282 | Disruption of PTPRO causes childhood-onset nephrotic syndrome |
Q34000212 | Distribution of TRPC6 in the cerebrospinal fluid-contacting nucleus of rat brain parenchyma and its expression in morphine dependence and withdrawal |
Q79537574 | Do mutations in COL4A1 or COL4A2 cause thin basement membrane nephropathy (TBMN)? |
Q36924116 | Drug discovery in focal and segmental glomerulosclerosis |
Q37051475 | Dual effects of RAS blockade on blood pressure and podocyte function |
Q37975102 | Educational paper: the podocytopathies |
Q39431317 | Effect of Cytochrome P450 Metabolites of Arachidonic Acid in Nephrology |
Q39333873 | Effect of TRPC6 knockdown on puromycin aminonucleoside-induced podocyte injury |
Q39815595 | Effect of down-regulation of TRPC6 on the puromycin aminonucleoside-induced apoptosis of mouse podocytes |
Q46960376 | Effects of caveolin-1 and P-ERK1/2 on Ang II-induced glomerular mesangial cell proliferation |
Q35881176 | Effects of stromal interaction molecule 1 or Orai1 overexpression on the associated proteins and permeability of podocytes |
Q33943315 | Enzymatic disease of the podocyte. |
Q28474937 | Establishment of protein delivery systems targeting podocytes |
Q38396121 | Evolutionary dynamics of metazoan TRP channels |
Q34759434 | Exclusion of homozygous PLCE1 (NPHS3) mutations in 69 families with idiopathic and hereditary FSGS. |
Q45752526 | Exome analysis resolves differential diagnosis of familial kidney disease and uncovers a potential confounding variant. |
Q33796482 | Exome sequencing and in vitro studies identified podocalyxin as a candidate gene for focal and segmental glomerulosclerosis. |
Q57980301 | Exome sequencing identified MYO1E and NEIL1 as candidate genes for human autosomal recessive steroid-resistant nephrotic syndrome |
Q34508359 | Exploring the genetic basis of early-onset chronic kidney disease |
Q34305480 | Expression of TRPC6 in renal cortex and hippocampus of mouse during postnatal development |
Q36727421 | Expression of trpC1 and trpC6 orthologs in zebrafish |
Q51725204 | Eye involvement in children with primary focal segmental glomerulosclerosis. |
Q35932259 | FAT1 mutations cause a glomerulotubular nephropathy |
Q42683699 | FK506 ameliorates podocyte injury in type 2 diabetic nephropathy by down-regulating TRPC6 and NFAT expression |
Q38244354 | Familial FSGS. |
Q57522621 | Familial Membranous Nephropathy: An X-Linked Genetic Susceptibility? |
Q37344693 | Familial forms of nephrotic syndrome. |
Q38086597 | Familial renal disease in soft-coated wheaten terriers |
Q28118243 | Fibroblast growth factor homologous factor 13 regulates Na+ channels and conduction velocity in murine hearts |
Q54324316 | Focal segmental glomerulosclerosis and end-stage kidney disease in children. |
Q36796123 | Focal segmental glomerulosclerosis and renal transplantation |
Q51774299 | Focal segmental glomerulosclerosis in patients with mandibuloacral dysplasia owing to ZMPSTE24 deficiency. |
Q37234710 | Focal segmental glomerulosclerosis is associated with a PDSS2 haplotype and, independently, with a decreased content of coenzyme Q10. |
Q35686453 | Focal segmental glomerulosclerosis: molecular genetics and targeted therapies |
Q38192853 | Focal segmental glomerulosclerosis: towards a better understanding for the practicing nephrologist |
Q34501710 | Functional NMDA receptors with atypical properties are expressed in podocytes |
Q41785473 | Functional distinctions in cytosolic calcium regulation between cells of the glomerular filtration barrier |
Q37250921 | Functional genetic variation in aminopeptidase A (ENPEP): lack of clear association with focal and segmental glomerulosclerosis (FSGS). |
Q36173605 | Functional role of TRPC proteins in native systems: implications from knockout and knock-down studies. |
Q89355497 | GAPVD1 and ANKFY1 Mutations Implicate RAB5 Regulation in Nephrotic Syndrome |
Q36947844 | Gain-of-function mutations in transient receptor potential C6 (TRPC6) activate extracellular signal-regulated kinases 1/2 (ERK1/2) |
Q42764201 | Generalizability of genetic findings related to kidney function and albuminuria |
Q26866422 | Genes and podocytes - new insights into mechanisms of podocytopathy |
Q90603450 | Genetic Disorders of the Glomerular Filtration Barrier |
Q53438899 | Genetic Interactions Between TRPC6 and NPHS1 Variants Affect Posttransplant Risk of Recurrent Focal Segmental Glomerulosclerosis. |
Q58580692 | Genetic Testing for Steroid-Resistant-Nephrotic Syndrome in an Outbred Population |
Q35675247 | Genetic association and gene-gene interaction analyses in African American dialysis patients with nondiabetic nephropathy |
Q47992013 | Genetic basis of adult-onset nephrotic syndrome and focal segmental glomerulosclerosis |
Q34674987 | Genetic causes of proteinuria and nephrotic syndrome: impact on podocyte pathobiology |
Q35793517 | Genetic diagnosis in consanguineous families with kidney disease by homozygosity mapping coupled with whole-exome sequencing |
Q37686687 | Genetic polymorphisms of ORAI1 and chronic kidney disease in Taiwanese population |
Q41827188 | Genetic susceptibility to HIV-associated nephropathy |
Q38193693 | Genetic testing for nephrotic syndrome and FSGS in the era of next-generation sequencing |
Q36985443 | Genetic testing in nephrotic syndrome--challenges and opportunities |
Q33361808 | Genetic testing in steroid-resistant nephrotic syndrome: when and how? |
Q47357418 | Genetic testing in steroid-resistant nephrotic syndrome: why, who, when and how? |
Q38155839 | Genetics and the nephron |
Q36772507 | Genetics of focal segmental glomerulosclerosis |
Q36269119 | Genetics of idiopathic nephrotic syndrome |
Q35187084 | Genetics of kidney failure and the evolving story of APOL1. |
Q37569711 | Genetics of nephrotic syndrome: new insights into molecules acting at the glomerular filtration barrier |
Q38114930 | Genetics of steroid-resistant nephrotic syndrome: a review of mutation spectrum and suggested approach for genetic testing |
Q26714036 | Genome-Wide Association Study Reveals Multiple Loci Influencing Normal Human Facial Morphology |
Q36719156 | Genome-wide high-density SNP-based linkage analysis of infantile hypertrophic pyloric stenosis identifies loci on chromosomes 11q14-q22 and Xq23. |
Q52599406 | Glomerular Endothelial Cells Stress and Cross-Talk With Podocytes in the Development of Diabetic Kidney Disease. |
Q27687257 | Glomerular diseases: FSGS. |
Q37774243 | Glomerular diseases: genetic causes and future therapeutics. |
Q54394528 | Glomerular podocytes express type 1 adenylate cyclase: inactivation results in susceptibility to proteinuria. |
Q35131205 | Glomerular proteinuria: a complex interplay between unique players |
Q37143338 | Glomerular type 1 angiotensin receptors augment kidney injury and inflammation in murine autoimmune nephritis |
Q35719874 | Gq signaling causes glomerular injury by activating TRPC6. |
Q30484244 | Hemopexin induces nephrin-dependent reorganization of the actin cytoskeleton in podocytes |
Q47861655 | Hereditary Podocytopathies in Adults: The Next Generation. |
Q34013421 | Hereditary nephrotic syndrome: a systematic approach for genetic testing and a review of associated podocyte gene mutations |
Q34053587 | High glucose induces podocyte apoptosis by stimulating TRPC6 via elevation of reactive oxygen species |
Q90363778 | High glucose reduces expression of podocin in cultured human podocytes by stimulating TRPC6 |
Q34213357 | High-density single nucleotide polymorphism screen in a large multiplex neural tube defect family refines linkage to loci at 7p21.1-pter and 2q33.1-q35. |
Q43251634 | How are podocytes affected in nail-patella syndrome? |
Q38217483 | How many Achilles' heels does a podocyte have? An update on podocyte biology. |
Q38393601 | Human genetics of nephrotic syndrome and the quest for precision medicine |
Q38726554 | Hydrogen peroxide suppresses TRPM4 trafficking to the apical membrane in mouse cortical collecting duct principal cells |
Q90726265 | Hypertension Induces Glomerulosclerosis in Phospholipase C Epsilon 1 Deficiency |
Q35865421 | Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels |
Q40066555 | Identification of BRAF as a new interactor of PLCepsilon1, the protein mutated in nephrotic syndrome type 3. |
Q37220295 | Identification of TRPCs genetic variants that modify risk for lung cancer based on the pathway and two-stage study |
Q33490128 | Identification of a putative network of actin-associated cytoskeletal proteins in glomerular podocytes defined by co-purified mRNAs |
Q34343895 | Identification of nephropathy candidate genes by comparing sclerosis-prone and sclerosis-resistant mouse strain kidney transcriptomes |
Q34405386 | Immunosuppression and renal outcome in congenital and pediatric steroid-resistant nephrotic syndrome |
Q38114119 | In pursuit of small molecule chemistry for calcium-permeable non-selective TRPC channels -- mirage or pot of gold? |
Q28546164 | In vivo Modeling Implicates APOL1 in Nephropathy: Evidence for Dominant Negative Effects and Epistasis under Anemic Stress |
Q39689329 | Incidences of membranous nephropathy versus focal segmental glomerulosclerosis: increase in the former or decline in the latter? |
Q33830100 | Increased glomerular filtration rate and impaired contractile function of mesangial cells in TRPC6 knockout mice |
Q30514178 | Inducible podocyte injury and proteinuria in transgenic zebrafish |
Q35554968 | Influence of tacrolimus on podocyte injury inducted by angiotensin II. |
Q36394692 | Inhibition of TRPC6 by protein kinase C isoforms in cultured human podocytes |
Q51260417 | Inhibition of TRPC6 channels ameliorates renal fibrosis and contributes to renal protection by soluble klotho. |
Q30559274 | Inhibition of the TRPC5 ion channel protects the kidney filter |
Q35780729 | Insulin increases surface expression of TRPC6 channels in podocytes: role of NADPH oxidases and reactive oxygen species |
Q35285585 | Insulin signaling: implications for podocyte biology in diabetic kidney disease |
Q38063325 | Insulin signalling to the kidney in health and disease. |
Q64994676 | Integrated Functional Genomic Analysis Enables Annotation of Kidney Genome-Wide Association Study Loci. |
Q33529557 | Integrating human and rodent data to identify the genetic factors involved in chronic kidney disease |
Q63869352 | Integration of Genetic Testing and Pathology for the Diagnosis of Adults with FSGS |
Q42846604 | Integration of phosphoinositide- and calmodulin-mediated regulation of TRPC6. |
Q37882053 | Integration of transient receptor potential canonical channels with lipids. |
Q24623493 | International Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel family |
Q30577189 | Intravital imaging of podocyte calcium in glomerular injury and disease |
Q36960139 | Inverted formin 2 mutations with variable expression in patients with sporadic and hereditary focal and segmental glomerulosclerosis |
Q41838197 | Involvement of phosphoinositide 3-kinase and PTEN protein in mechanism of activation of TRPC6 protein in vascular smooth muscle cells |
Q57177158 | Ion Channels and Transporters in Inflammation: Special Focus on TRP Channels and TRPC6 |
Q92730289 | Ion channels and transporters in diabetic kidney disease |
Q36439177 | Ion channels in renal disease. |
Q42217411 | Is the antiproteinuric effect of cyclosporine a independent of its immunosuppressive function in T cells? |
Q46894504 | Kidney disease and African ancestry |
Q50235923 | Klotho May Ameliorate Proteinuria by Targeting TRPC6 Channels in Podocytes. |
Q37078415 | LMX1B mutations cause hereditary FSGS without extrarenal involvement |
Q54424682 | Lack of association between transient receptor potential cation channel 6 polymorphisms and primary membranous glomerulonephritis. |
Q26738305 | Large-Conductance Calcium-Activated Potassium Channels in Glomerulus: From Cell Signal Integration to Disease |
Q36341780 | Late onset of familial nephrotic syndrome associated with a compound heterozygous mutation of the podocin-encoding gene |
Q33471500 | Ligation of alpha-dystroglycan on podocytes induces intracellular signaling: a new mechanism for podocyte effacement? |
Q91846349 | LncRNA SOX2OT alleviates the high glucose-induced podocytes injury through autophagy induction by the miR-9/SIRT1 axis |
Q53570369 | Losartan treating podocyte injury induced by Ang II via downregulation of TRPC6 in podocytes. |
Q33588228 | Lovastatin inhibits human B lymphoma cell proliferation by reducing intracellular ROS and TRPC6 expression |
Q33866208 | Low prevalence of NPHS2 mutations in African American children with steroid-resistant nephrotic syndrome |
Q30541167 | MYO1E mutations and childhood familial focal segmental glomerulosclerosis |
Q34506500 | Mammalian target of rapamycin complex 2 signaling pathway regulates transient receptor potential cation channel 6 in podocytes |
Q57189799 | Mechanisms underlying modulation of podocyte TRPC6 channels by suPAR: Role of NADPH oxidases and Src family tyrosine kinases |
Q34336370 | Metabolism, energetics, and lipid biology in the podocyte - cellular cholesterol-mediated glomerular injury. |
Q28593398 | Mice lacking Homer 1 exhibit a skeletal myopathy characterized by abnormal transient receptor potential channel activity |
Q36266540 | MicroRNA-30 family members regulate calcium/calcineurin signaling in podocytes |
Q38982416 | Minimal change disease and idiopathic FSGS: manifestations of the same disease. |
Q36978935 | Minimal change nephropathy and focal segmental glomerulosclerosis |
Q50603331 | Modulating alpha-actinin-4 dynamics in podocytes. |
Q92535773 | Modulation of Transient Receptor Potential C Channel Activity by Cholesterol |
Q52715295 | Molecular Mechanisms of Proteinuria in Focal Segmental Glomerulosclerosis. |
Q38310654 | Molecular and genetic basis of inherited nephrotic syndrome |
Q56919661 | Molecular basis for the sensitivity of TRP channels to polyunsaturated fatty acids |
Q33845904 | Molecular genetic analysis of podocyte genes in focal segmental glomerulosclerosis--a review |
Q37156672 | Molecular pathology of nephrotic syndrome in childhood: a contemporary approach to diagnosis |
Q90951107 | Molecular stratification of idiopathic nephrotic syndrome |
Q90054179 | Mouse transient receptor potential channel type 6 selectively regulates agonist-induced platelet function |
Q41688065 | Multiple Targets for Novel Therapy of FSGS Associated with Circulating Permeability Factor |
Q58736452 | Mutational screening of inverted formin 2 in adult-onset focal segmental glomerulosclerosis or minimal change patients from the Czech Republic |
Q41822498 | Mutations in INF2 are a major cause of autosomal dominant focal segmental glomerulosclerosis |
Q36826069 | Mutations in the INF2 gene account for a significant proportion of familial but not sporadic focal and segmental glomerulosclerosis |
Q24292947 | Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis |
Q24293205 | Mutations in the gene that encodes the F-actin binding protein anillin cause FSGS |
Q38040813 | NFAT gene family in inflammation and cancer |
Q28296660 | NOX2 interacts with podocyte TRPC6 channels and contributes to their activation by diacylglycerol: essential role of podocin in formation of this complex |
Q50888451 | NPHS2 p.V290M mutation in late-onset steroid-resistant nephrotic syndrome. |
Q33372592 | NPHS2 variation in focal and segmental glomerulosclerosis |
Q41885647 | NSAIDs acutely inhibit TRPC channels in freshly isolated rat glomeruli |
Q39261176 | Neph1, a component of the kidney slit diaphragm, is tyrosine-phosphorylated by the Src family tyrosine kinase and modulates intracellular signaling by binding to Grb2. |
Q55376726 | Nephrin Signaling in the Podocyte: An Updated View of Signal Regulation at the Slit Diaphragm and Beyond. |
Q36807046 | Nephrin binds to the COOH terminus of a large-conductance Ca2+-activated K+ channel isoform and regulates its expression on the cell surface |
Q63434594 | Nephrin mutations cause childhood- and adult-onset focal segmental glomerulosclerosis |
Q41166606 | Neurexin-1, a presynaptic adhesion molecule, localizes at the slit diaphragm of the glomerular podocytes in kidneys |
Q47812978 | New Aspects of the Contribution of ER to SOCE Regulation: TRPC Proteins as a Link Between Plasma Membrane Ion Transport and Intracellular Ca2+ Stores |
Q39238888 | New Insights into Podocyte Biology in Glomerular Health and Disease |
Q42428361 | New TRPC6 gain-of-function mutation in a non-consanguineous Dutch family with late-onset focal segmental glomerulosclerosis. |
Q38025336 | New developments in steroid-resistant nephrotic syndrome |
Q89533672 | New insight into podocyte slit diaphragm, a therapeutic target of proteinuria |
Q49159738 | New insights into mechanisms of glomerular injury and repair from the 10th International Podocyte Conference 2014. |
Q37542923 | New insights into the role of podocytes in proteinuria |
Q34559353 | Next-generation sequencing to dissect hereditary nephrotic syndrome in mice identifies a hypomorphic mutation in Lamb2 and models Pierson's syndrome |
Q54355255 | No association between the SNPs (rs56134796; rs3824934; rs41302375) in the TRPC6 gene promoter and infantile hypertrophic pyloric stenosis in Chinese people. |
Q34496366 | Non-immunologic actions of calcineurin inhibitors in proteinuric kidney diseases |
Q50333254 | Non-muscle myosins and the podocyte |
Q26781358 | Nonimmunologic targets of immunosuppressive agents in podocytes |
Q63461212 | Notions récentes sur la génétique du syndrome néphrotique cortico-résistant |
Q56973183 | Novel INF2 mutations in an Italian cohort of patients with focal segmental glomerulosclerosis, renal failure and Charcot-Marie-Tooth neuropathy |
Q48090049 | Novel NPHS2 variant in patients with familial steroid-resistant nephrotic syndrome with early onset, slow progression and dominant inheritance pattern |
Q91635236 | Novel Targets for Stroke Therapy: Special Focus on TRPC Channels and TRPC6 |
Q41697134 | Novel mutations in the inverted formin 2 gene of Chinese families contribute to focal segmental glomerulosclerosis |
Q38335626 | Nox and renal disease. |
Q46736252 | Nuclear factor of activated T cells mediates RhoA-induced fibronectin upregulation in glomerular podocytes |
Q36812431 | Nuclear factor κB mediates suppression of canonical transient receptor potential 6 expression by reactive oxygen species and protein kinase C in kidney cells |
Q99564962 | Nuclear receptors in podocyte biology and glomerular disease |
Q35840462 | Nuclear relocation of the nephrin and CD2AP-binding protein dendrin promotes apoptosis of podocytes |
Q38338547 | One hundred ways to kill a podocyte |
Q39154682 | Opposing effects of podocin on the gating of podocyte TRPC6 channels evoked by membrane stretch or diacylglycerol |
Q90835768 | PLCE1 regulates the migration, proliferation, and differentiation of podocytes |
Q57193128 | Panel sequencing distinguishes monogenic forms of nephritis from nephrosis in children |
Q33919216 | Partial uniparental isodisomy of chromosome 16 unmasks a deleterious biallelic mutation in IFT140 that causes Mainzer-Saldino syndrome |
Q37812564 | Pathogenesis and therapy of focal segmental glomerulosclerosis: an update |
Q28067299 | Pathogenesis of Focal Segmental Glomerulosclerosis |
Q36704678 | Pathophysiology of focal segmental glomerulosclerosis |
Q49378996 | Patient Engagement in Kidney Research: Opportunities and Challenges Ahead. |
Q37264382 | Pdx-1 activates islet α- and β-cell proliferation via a mechanism regulated by transient receptor potential cation channels 3 and 6 and extracellular signal-regulated kinases 1 and 2. |
Q38738516 | Permeability factors in nephrotic syndrome and focal segmental glomerulosclerosis |
Q58801731 | Permeation and Rectification in Canonical Transient Receptor Potential-6 (TRPC6) Channels |
Q37798861 | Pharmacological Modulation of Diacylglycerol-Sensitive TRPC3/6/7 Channels |
Q40495134 | Pharmacological inhibition of FSGS-related TRPC6 gain of function mutants by semisynthetic larixol-derived compounds. |
Q33764566 | Phosphodiesterase 5 inhibition ameliorates angiontensin II-induced podocyte dysmotility via the protein kinase G-mediated downregulation of TRPC6 activity |
Q39614603 | Phospholipase C epsilon (PLCε) induced TRPC6 activation: a common but redundant mechanism in primary podocytes |
Q33814888 | Phosphoproteomic analysis reveals regulatory mechanisms at the kidney filtration barrier |
Q41824937 | Phosphorylation of Nephrin Triggers Ca2+ Signaling by Recruitment and Activation of Phospholipase C-{gamma}1. |
Q50721783 | Phylogeny and expression of canonical transient receptor potential (TRPC) genes in developing zebrafish. |
Q37072447 | Physiology and pathophysiology of canonical transient receptor potential channels |
Q38870270 | Pleiotropic signaling evoked by tumor necrosis factor in podocytes |
Q35768439 | Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels |
Q28256662 | Podocin inactivation in mature kidneys causes focal segmental glomerulosclerosis and nephrotic syndrome |
Q53546425 | Podocin organizes ion channel-lipid supercomplexes: implications for mechanosensation at the slit diaphragm. |
Q38653995 | Podocyte Purinergic P2X4 Channels Are Mechanotransducers That Mediate Cytoskeletal Disorganization |
Q33419853 | Podocyte dysfunction in atypical haemolytic uraemic syndrome |
Q36360722 | Podocyte injury in diabetic nephropathy: implications of angiotensin II-dependent activation of TRPC channels |
Q38061941 | Podocyte mitosis - a catastrophe. |
Q26852463 | Podocyte pathology and nephropathy - sphingolipids in glomerular diseases |
Q38940494 | Podocyte-actin dynamics in health and disease |
Q33705025 | Podocyte-specific overexpression of wild type or mutant trpc6 in mice is sufficient to cause glomerular disease |
Q26766118 | Podocytes |
Q37036858 | Podocytopathy in diabetes: a metabolic and endocrine disorder |
Q24312154 | Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible |
Q92631461 | Post-Translational Modification and Natural Mutation of TRPC Channels |
Q41976212 | Potential and pitfalls in the genetic diagnosis of kidney diseases |
Q37118487 | Primer: strategies for identifying genes involved in renal disease |
Q34145974 | Prkdc participates in mitochondrial genome maintenance and prevents Adriamycin-induced nephropathy in mice. |
Q31171853 | Prognostic value and link to atrial fibrillation of soluble Klotho and FGF23 in hemodialysis patients |
Q35234337 | Progression of glomerular and tubular disease in pediatrics |
Q47574932 | Prohibitin Signaling at the Kidney Filtration Barrier. |
Q46311217 | Proline-dependent and basophilic kinases phosphorylate human TRPC6 at serine 14 to control channel activity through increased membrane expression |
Q89164280 | Protective role of Trpc6 knockout in the progression of diabetic kidney disease |
Q41197267 | Protein kinase C-dependent phosphorylation of transient receptor potential canonical 6 (TRPC6) on serine 448 causes channel inhibition |
Q33943310 | Proteinuria: an enzymatic disease of the podocyte? |
Q57652246 | Proteinuric Kidney Diseases: A Podocyte's Slit Diaphragm and Cytoskeleton Approach |
Q41196444 | Proteomic analysis of the slit diaphragm complex: CLIC5 is a protein critical for podocyte morphology and function |
Q88959338 | Pyrazolo[1,5-a]pyrimidine TRPC6 antagonists for the treatment of gastric cancer |
Q40250028 | Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels |
Q94461672 | RNA-seq analysis reveals TRPC genes to impact an unexpected number of metabolic and regulatory pathways |
Q33715807 | Rapid detection of monogenic causes of childhood-onset steroid-resistant nephrotic syndrome |
Q34577537 | Rare hereditary COL4A3/COL4A4 variants may be mistaken for familial focal segmental glomerulosclerosis |
Q30504293 | Reactive oxygen species-mediated TRPC6 protein activation in vascular myocytes, a mechanism for vasoconstrictor-regulated vascular tone |
Q57825276 | Recent Progress in the Pathogenesis of Nephrotic Proteinuria |
Q58620516 | Recurrent autosomal-dominant focal segmental glomerulosclerosis |
Q53817240 | Reduced INF2 expression in nephrotic syndrome is possibly related to clinical severity of steroid resistance in children. |
Q39390200 | Regulation of Nephrin Phosphorylation in Diabetes and Chronic Kidney Injury |
Q34267211 | Regulation of TRPC6 Channels by Non-Steroidal Anti-Inflammatory Drugs |
Q28279142 | Regulation of ion channels by secreted Klotho: mechanisms and implications |
Q36450027 | Regulation of transport in the connecting tubule and cortical collecting duct |
Q42254379 | Renal and Hematological Effects of CLCF-1, a B-Cell-Stimulating Cytokine of the IL-6 Family. |
Q38203501 | Renal biopsy: use of biomarkers as a tool for the diagnosis of focal segmental glomerulosclerosis |
Q53612706 | Renal complications in 6p duplication syndrome: microarray-based investigation of the candidate gene(s) for the development of congenital anomalies of the kidney and urinary tract (CAKUT) and focal segmental glomerular sclerosis (FSGS). |
Q49886784 | Renal physiology: TRPC5 inhibition to treat progressive kidney disease. |
Q80387822 | Renin-angiotensin axis blockade reduces proteinuria in presymptomatic patients with familial FSGS |
Q39060342 | Renoprotection: focus on TRPV1, TRPV4, TRPC6 and TRPM2. |
Q87175790 | Report of novel genetic variation in NPHS2 gene associated with idiopathic nephrotic syndrome in South Indian children |
Q50043947 | Research advances in the association between transient receptor potential cation channel 6 and kidney disease |
Q35543167 | Review series: The cell biology of renal filtration |
Q37808491 | Role of Angiotensin II in the Development of Nephropathy and Podocytopathy of Diabetes |
Q92536780 | Role of Podocyte Injury in Glomerulosclerosis |
Q38154296 | Role of Rho-GTPases and their regulatory proteins in glomerular podocyte function |
Q93055504 | Role of Transient Receptor Potential Canonical Channel 6 (TRPC6) in Diabetic Kidney Disease by Regulating Podocyte Actin Cytoskeleton Rearrangement |
Q37590634 | Role of altered insulin signaling pathways in the pathogenesis of podocyte malfunction and microalbuminuria |
Q36703547 | Role of renal TRP channels in physiology and pathology |
Q33846395 | Role of transient receptor potential channel 6 in the odontogenic differentiation of human dental pulp cells |
Q37207026 | Roles of TRP channels in the development of cardiac hypertrophy |
Q39351105 | Roles of transient receptor potential channels in regulation of vascular and epithelial barriers |
Q24304302 | SNF8, a member of the ESCRT-II complex, interacts with TRPC6 and enhances its channel activity |
Q45746271 | Scavengers of reactive oxygen species, paracalcitol, RhoA, and Rac-1 inhibitors and tacrolimus inhibit angiotensin II-induced actions on glomerular permeability |
Q34695450 | Screening for NPHS2 mutations may help predict FSGS recurrence after transplantation |
Q34986719 | Screening for mutations in kidney-related genes using SURVEYOR nuclease for cleavage at heteroduplex mismatches. |
Q38830289 | Second Messenger-Operated Calcium Entry Through TRPC6. |
Q34963488 | Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound |
Q37432783 | Sensing pressure in the cardiovascular system: Gq-coupled mechanoreceptors and TRP channels. |
Q51299126 | Sildenafil Prevents Podocyte Injury via PPAR-γ-Mediated TRPC6 Inhibition. |
Q41499068 | Single and Transient Ca(2+) Peaks in Podocytes do not induce Changes in Glomerular Filtration and Perfusion |
Q34273590 | Single-channel analysis of TRPC channels in the podocytes of freshly isolated Glomeruli |
Q37407881 | Slit diaphragm dysfunction in proteinuric states: identification of novel therapeutic targets for nephrotic syndrome |
Q53546414 | Slit diaphragm junctional complex and regulation of the cytoskeleton. |
Q55041007 | Slit or pore? A mutation of the ion channel TRPC6 causes FSGS. |
Q37797839 | Specialized roles for cysteine cathepsins in health and disease. |
Q39935646 | Specific TRPC6 channel activation, a novel approach to stimulate keratinocyte differentiation |
Q36677399 | Specific podocin mutations correlate with age of onset in steroid-resistant nephrotic syndrome. |
Q38991259 | Steroid-resistant nephrotic syndrome: a persistent challenge for pediatric nephrology |
Q49500608 | Steroid-resistant nephrotic syndrome: past and current perspectives |
Q36381888 | Store-operated Ca2+ channel in renal microcirculation and glomeruli |
Q38661145 | Stressed podocytes-mechanical forces, sensors, signaling and response. |
Q90155507 | Structural basis for pharmacological modulation of the TRPC6 channel |
Q88488611 | Structure of the receptor-activated human TRPC6 and TRPC3 ion channels |
Q57450480 | Structure-function analyses of the ion channel TRPC3 reveal that its cytoplasmic domain allosterically modulates channel gating |
Q33560817 | Subfractionation, characterization, and in-depth proteomic analysis of glomerular membrane vesicles in human urine |
Q37616991 | Susceptibility genes in common complex kidney disease |
Q37170764 | Susceptibility loci for murine HIV-associated nephropathy encode trans-regulators of podocyte gene expression |
Q36294421 | Sustained activation of N-methyl-D-aspartate receptors in podoctyes leads to oxidative stress, mobilization of transient receptor potential canonical 6 channels, nuclear factor of activated T cells activation, and apoptotic cell death |
Q42722911 | Synaptopodin Limits TRPC6 Podocyte Surface Expression and Attenuates Proteinuria |
Q42759660 | TGF-β1 induces podocyte injury through Smad3-ERK-NF-κB pathway and Fyn-dependent TRPC6 phosphorylation |
Q29616673 | TRP channels |
Q38111283 | TRP channels |
Q36217258 | TRP channels in disease |
Q50021444 | TRP'ing up chronic kidney disease |
Q24624455 | TRP-ing up heart and vessels: canonical transient receptor potential channels and cardiovascular disease |
Q50999476 | TRPC Channels in Health and Disease. |
Q92257319 | TRPC Channels in Proteinuric Kidney Diseases |
Q38287204 | TRPC Channels: Prominent Candidates of Underlying Mechanism in Neuropsychiatric Diseases |
Q37424405 | TRPC channel lipid specificity and mechanisms of lipid regulation |
Q34993566 | TRPC channel modulation in podocytes-inching toward novel treatments for glomerular disease |
Q38510489 | TRPC channel modulators and their potential therapeutic applications |
Q89468002 | TRPC channels: Structure, function, regulation and recent advances in small molecular probes |
Q33896913 | TRPC1 channels are critical for hypertrophic signaling in the heart |
Q30478281 | TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy |
Q47735658 | TRPC5 Does Not Cause or Aggravate Glomerular Disease |
Q40974180 | TRPC6 G757D Loss-of-Function Mutation Associates with FSGS. |
Q37072696 | TRPC6 channel activation promotes neonatal glomerular mesangial cell apoptosis via calcineurin/NFAT and FasL/Fas signaling pathways. |
Q28081895 | TRPC6 channel as an emerging determinant of the podocyte injury susceptibility in kidney diseases |
Q34211578 | TRPC6 channels and their binding partners in podocytes: role in glomerular filtration and pathophysiology |
Q34695410 | TRPC6 enhances angiotensin II-induced albuminuria |
Q51137789 | TRPC6 gene promoter polymorphisms in steroid resistant nephrotic syndrome children. |
Q24652809 | TRPC6 in glomerular health and disease: what we know and what we believe |
Q57177412 | TRPC6 in simulated microgravity of intervertebral disc cells |
Q60915176 | TRPC6 inactivation does not affect loss of renal function in nephrotoxic serum glomerulonephritis in rats, but reduces severity of glomerular lesions |
Q89985512 | TRPC6 inactivation does not protect against diabetic kidney disease in streptozotocin (STZ)-treated Sprague-Dawley rats |
Q28594959 | TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function |
Q51637426 | TRPC6 mutational analysis in a large cohort of patients with focal segmental glomerulosclerosis. |
Q37139035 | TRPC6 mutations associated with focal segmental glomerulosclerosis cause constitutive activation of NFAT-dependent transcription. |
Q35206224 | TRPC6 single nucleotide polymorphisms and progression of idiopathic membranous nephropathy |
Q57364318 | TRPCs as MS Channels |
Q37216903 | TRPMLs: in sickness and in health |
Q38423897 | TRP_2, a lipid/trafficking domain that mediates diacylglycerol-induced vesicle fusion |
Q36670208 | TRPpathies |
Q38222944 | TRPs as chemosensors (ROS, RNS, RCS, gasotransmitters). |
Q37089726 | Tackling heart failure in the twenty-first century |
Q35959709 | Targeted next-generation sequencing in steroid-resistant nephrotic syndrome: mutations in multiple glomerular genes may influence disease severity |
Q37710561 | Targeting TRPC6 channels in oesophageal carcinoma growth. |
Q38770231 | Targeting the podocyte cytoskeleton: from pathogenesis to therapy in proteinuric kidney disease |
Q57172531 | The Calcium-Dependent Protease Calpain-1 Links TRPC6 Activity to Podocyte Injury |
Q52685434 | The Efficacy of Puromycin and Adriamycin for Induction of Glomerular Failure in Larval Zebrafish Validated by an Assay of Glomerular Permeability Dynamics. |
Q37032671 | The Genetics of Nephrotic Syndrome |
Q27011243 | The Impact of Histologic Variants on FSGS Outcomes |
Q93222971 | The Klotho proteins in health and disease |
Q81826543 | The R229Q mutation in NPHS2 may predispose to proteinuria in thin-basement-membrane nephropathy |
Q33671746 | The Role of Angiotensin II in Glomerular Volume Dynamics and Podocyte Calcium Handling |
Q92991647 | The Role of Glucocorticoid Receptors in Podocytes and Nephrotic Syndrome |
Q38222953 | The TRPC family of TRP channels: roles inferred (mostly) from knockout mice and relationship to ORAI proteins |
Q90468407 | The Use of Genomics To Drive Kidney Disease Drug Discovery and Development |
Q33943247 | The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A. |
Q27006914 | The function of endocytosis in podocytes |
Q36515022 | The genetic risk of kidney disease in type 2 diabetes |
Q34020798 | The glomerulus--a view from the outside--the podocyte |
Q38215903 | The glomerulus: the sphere of influence |
Q37834456 | The history of TRP channels, a commentary and reflection |
Q38263509 | The importance of podocyte adhesion for a healthy glomerulus |
Q39953304 | The molecular and functional phenotype of glomerular podocytes reveals key features of contractile smooth muscle cells |
Q53013430 | The novel role of TRPC6 in vitamin D ameliorating podocyte injury in STZ-induced diabetic rats. |
Q37951800 | The podocyte as a target for therapies--new and old. |
Q37949258 | The podocyte cytoskeleton--key to a functioning glomerulus in health and disease |
Q38133715 | The podocyte slit diaphragm--from a thin grey line to a complex signalling hub. |
Q36474870 | The podocyte's response to injury: role in proteinuria and glomerulosclerosis |
Q51993739 | The podocyte-specific inactivation of Lmx1b, Ldb1 and E2a yields new insight into a transcriptional network in podocytes. |
Q37436623 | The proteoglycan syndecan 4 regulates transient receptor potential canonical 6 channels via RhoA/Rho-associated protein kinase signaling |
Q38062343 | The renal biopsy in the genomic era. |
Q26824023 | The renal channelopathies |
Q36467553 | The renin-angiotensin system in glomerular podocytes: mediator of glomerulosclerosis and link to hypertensive nephropathy |
Q38572369 | The role of alpha-actinin-4 in human kidney disease |
Q41956838 | The role of mechanical tension on lipid raft dependent PDGF-induced TRPC6 activation |
Q36997933 | The role of podocytes in proteinuria |
Q38100984 | The role of the podocyte in albumin filtration |
Q37527790 | The role of transient receptor potential channels in kidney disease |
Q42486012 | The serine 814 of TRPC6 is phosphorylated under unstimulated conditions |
Q34105121 | The spectrum of MYH9-associated nephropathy |
Q36780741 | The spectrum of podocytopathies: a unifying view of glomerular diseases. |
Q37852820 | The transient receptor potential family of ion channels |
Q34927551 | Therapeutic approaches to ion channel diseases |
Q38261675 | Therapeutic target for nephrotic syndrome: Identification of novel slit diaphragm associated molecules |
Q37228164 | Therapeutic targets in focal and segmental glomerulosclerosis |
Q33872286 | Toward the development of podocyte-specific drugs |
Q37448233 | Tracking the fate of glomerular epithelial cells in vivo using serial multiphoton imaging in new mouse models with fluorescent lineage tags. |
Q92677820 | Transient Receptor Potential Channels and Endothelial Cell Calcium Signaling |
Q33562143 | Transient receptor potential (TRP) channels: a clinical perspective |
Q37405051 | Transient receptor potential channel 6 (TRPC6) protects podocytes during complement-mediated glomerular disease. |
Q37686351 | Transient receptor potential channelopathies |
Q36734951 | Transient receptor potential channels as drug targets |
Q28244558 | Transient receptor potential channels as therapeutic targets |
Q36000376 | Transient receptor potential channels in the vasculature |
Q37720127 | Transient receptor proteins illuminated: current views on TRPs and disease |
Q28088653 | Translating genetic findings in hereditary nephrotic syndrome: the missing loops |
Q57049336 | Treatment of steroid-resistant nephrotic syndrome in the genomic era |
Q33295387 | TrpC3 regulates hypertrophy-associated gene expression without affecting myocyte beating or cell size |
Q55435365 | Trpc6 inactivation confers protection in a model of severe nephrosis in rats. |
Q37078084 | Two Korean infants with genetically confirmed congenital nephrotic syndrome of Finnish type |
Q37903259 | Tyrosine kinase signaling in kidney glomerular podocytes |
Q42133639 | Tyrosine phosphorylation-dependent activation of TRPC6 regulated by PLC-γ1 and nephrin: effect of mutations associated with focal segmental glomerulosclerosis |
Q38356739 | Understanding podocytopathy and its relevance to clinical nephrology |
Q36100123 | Understanding the mechanisms of proteinuria: therapeutic implications |
Q34055958 | Up-regulation of the homophilic adhesion molecule sidekick-1 in podocytes contributes to glomerulosclerosis |
Q37052033 | Using Population Genetics to Interrogate the Monogenic Nephrotic Syndrome Diagnosis in a Case Cohort |
Q34003179 | VEGF regulates TRPC6 channels in podocytes |
Q36312650 | VEGF165b overexpression restores normal glomerular water permeability in VEGF164-overexpressing adult mice |
Q38482164 | Variable renal phenotype in a family with an INF2 mutation |
Q93074032 | WITHDRAWN: Local miscommunications between glomerular cells as potential therapeutic targets for crescentic glomerulonephritides |
Q51732914 | WT1 and NPHS2 mutations in Korean children with steroid-resistant nephrotic syndrome. |
Q43746028 | WT1 gene mutations in Chinese children with early onset nephrotic syndrome |
Q26796624 | Wnt/β-catenin signaling and kidney fibrosis |
Q85845784 | Wnt/β-catenin signalling pathway mediates high glucose induced cell injury through activation of TRPC6 in podocytes |
Q88333477 | [Correlation between expressions of VEGF and TRPC6 and their roles in podocyte injury in rats with diabetic nephropathy] |
Q41809171 | cAMP activates TRPC6 channels via the phosphatidylinositol 3-kinase (PI3K)-protein kinase B (PKB)-mitogen-activated protein kinase kinase (MEK)-ERK1/2 signaling pathway. |
Q36959403 | miR-200 family promotes podocyte differentiation through repression of RSAD2. |
Q58214831 | α-Actinin-4 Is Required for Normal Podocyte Adhesion |
Search more.