review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.3389/FENDO.2014.00169 |
P8608 | Fatcat ID | release_3uwayftm4vamrkae6bu3bprdlq |
P932 | PMC publication ID | 4196552 |
P698 | PubMed publication ID | 25352833 |
P5875 | ResearchGate publication ID | 267741629 |
P50 | author | Sandra Merscher | Q58130679 |
P2093 | author name string | Armando J Mendez | |
Christopher E Pedigo | |||
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A novel human apolipoprotein (apoM) | Q22010708 | ||
Positionally cloned gene for a novel glomerular protein--nephrin--is mutated in congenital nephrotic syndrome | Q24314612 | ||
SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element | Q24318461 | ||
Hypoxia-inducible protein 2 is a novel lipid droplet protein and a specific target gene of hypoxia-inducible factor-1 | Q24338684 | ||
Intracellular cholesterol transport | Q24553317 | ||
Association of trypanolytic ApoL1 variants with kidney disease in African Americans | Q24606581 | ||
Human lecithin-cholesterol acyltransferase gene: complete gene sequence and sites of expression | Q24609462 | ||
A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood | Q24614744 | ||
APOL1 genetic variants in focal segmental glomerulosclerosis and HIV-associated nephropathy | Q24631837 | ||
APOL1 localization in normal kidney and nondiabetic kidney disease | Q24631960 | ||
Missense mutations in the APOL1 gene are highly associated with end stage kidney disease risk previously attributed to the MYH9 gene | Q24632288 | ||
Nephrin is specifically located at the slit diaphragm of glomerular podocytes | Q24644718 | ||
The LDL receptor | Q24658039 | ||
NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome | Q28116208 | ||
CD2AP is expressed with nephrin in developing podocytes and is found widely in mature kidney and elsewhere | Q28139178 | ||
Regulation of HMG-CoA reductase expression by hypoxia | Q39985039 | ||
Megalin is a receptor for apolipoprotein M, and kidney-specific megalin-deficiency confers urinary excretion of apolipoprotein M. | Q40036165 | ||
Inflammatory cytokines disrupt LDL-receptor feedback regulation and cause statin resistance: a comparative study in human hepatic cells and mesangial cells | Q40106766 | ||
The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor | Q40428631 | ||
Gene expression profiling of the hypoxia signaling pathway in hypoxia-inducible factor 1alpha null mouse embryonic fibroblasts | Q40605721 | ||
PPAR agonists protect mesangial cells from interleukin 1beta-induced intracellular lipid accumulation by activating the ABCA1 cholesterol efflux pathway | Q40669358 | ||
Analysis of glomerulosclerosis and atherosclerosis in lecithin cholesterol acyltransferase-deficient mice. | Q40716232 | ||
Renal cortical cholesterol accumulation is an integral component of the systemic stress response | Q40764786 | ||
Dysregulation of LDL receptor under the influence of inflammatory cytokines: a new pathway for foam cell formation | Q40769421 | ||
Lipoprotein metabolism and renal failure | Q40912350 | ||
Lipid nephrotoxicity in chronic progressive glomerular and tubulo-interstitial disease | Q41533607 | ||
Abnormalities of lipoprotein metabolism in patients with the nephrotic syndrome | Q68877409 | ||
Cholesterol and lipid disturbances in renal disease: the natural history of uremic dyslipidemia and the impact of hemodialysis and continuous ambulatory peritoneal dialysis | Q69146954 | ||
Increased lipoprotein-remnant formation in chronic renal failure | Q70379782 | ||
Familial serum-cholesterol esterification failure. A new inborn error of metabolism | Q72363770 | ||
Cell toxicity induced by inhibition of acyl coenzyme A:cholesterol acyltransferase and accumulation of unesterified cholesterol | Q72631536 | ||
Apolipoprotein E2, renal failure and lipid abnormalities in non-insulin-dependent diabetes mellitus | Q72857300 | ||
Lipoprotein glomerulopathy: first report in a Chinese male | Q72870257 | ||
Apolipoprotein E polymorphism in IgA nephropathy | Q73102267 | ||
Getting a foothold in nephrotic syndrome | Q73606344 | ||
Novel glomerular lipoprotein deposits associated with apolipoprotein E2 homozygosity | Q73798219 | ||
Lipid abnormalities in renal disease | Q73874641 | ||
Decreased cellular cholesterol efflux is a common cause of familial hypoalphalipoproteinemia: role of the ABCA1 gene mutations | Q74348218 | ||
Apolipoprotein E4 reduces risk of diabetic nephropathy in patients with NIDDM | Q74411565 | ||
Secretion of apoB- and apoA-I-containing lipoproteins by chick kidney | Q74472008 | ||
Renal injury in apolipoprotein E-deficient mice | Q74606513 | ||
Identification of the abnormal cholestatic lipoprotein (LP-X) in familial lecithin:Cholesterol acyltransferase deficiency | Q77919988 | ||
Severe hyperlipidemia causes impaired renin-angiotensin system function in apolipoprotein E deficient mice | Q81090101 | ||
Estimation of oxidative stress markers in chronic kidney disease | Q82433186 | ||
The polysaccharide fraction of Propionibacterium acnes modulates the development of experimental focal segmental glomerulosclerosis | Q83275712 | ||
Characteristic, polymorphism and expression distribution of LCAT gene in a Mongolian gerbil model for hyperlipidemia | Q87410404 | ||
A novel in vivo lecithin-cholesterol acyltransferase (LCAT)-deficient mouse expressing predominantly LpX is associated with spontaneous glomerulopathy | Q41772991 | ||
Cytotoxic cholesterol is generated by the hydrolysis of cytoplasmic cholesteryl ester and transported to the plasma membrane | Q41922968 | ||
HDL in CKD: how good is the "good cholesterol?". | Q42547433 | ||
Weekly cyclodextrin administration normalizes cholesterol metabolism in nearly every organ of the Niemann-Pick type C1 mouse and markedly prolongs life. | Q42704514 | ||
Cholesterol, a cell size-dependent signal that regulates glucose metabolism and gene expression in adipocytes | Q42830499 | ||
NMR identifies atherogenic lipoprotein abnormalities in early diabetic nephropathy that are unrecognized by conventional analysis | Q43152800 | ||
Niacin improves renal lipid metabolism and slows progression in chronic kidney disease | Q43251558 | ||
Sturucture of an abnormal plasma lipoprotein (LP-X) characterizing obstructive jaundice | Q43468093 | ||
Free cholesterol loading of macrophages is associated with widespread mitochondrial dysfunction and activation of the mitochondrial apoptosis pathway | Q43726505 | ||
The heart in Tangier disease. Severe coronary atherosclerosis with near absence of high-density lipoprotein cholesterol | Q43885406 | ||
Mesangial expansion associated with glomerular endothelial cell activation and macrophage recruitment is developing in hyperlipidaemic apoE null mice | Q44231164 | ||
Podocyte expression of hypoxia-inducible factor (HIF)-1 and HIF-2 during glomerular development | Q44378907 | ||
Induction of renoprotective gene expression by cobalt ameliorates ischemic injury of the kidney in rats | Q44486202 | ||
Saturated free fatty acid toxicity. II. Lipid accumulation, ultrastructural alterations, and toxicity in mammalian cells in culture | Q44802333 | ||
Accelerated nephropathy in diabetic apolipoprotein e-knockout mouse: role of advanced glycation end products. | Q45000524 | ||
A founder haplotype of APOE-Sendai mutation associated with lipoprotein glomerulopathy | Q45172544 | ||
Virus-mediated transduction of apolipoprotein E (ApoE)-sendai develops lipoprotein glomerulopathy in ApoE-deficient mice | Q45741461 | ||
Effects of atorvastatin on kidney outcomes and cardiovascular disease in patients with diabetes: an analysis from the Collaborative Atorvastatin Diabetes Study (CARDS). | Q45961602 | ||
Disruption of the murine lecithin:cholesterol acyltransferase gene causes impairment of adrenal lipid delivery and up-regulation of scavenger receptor class B type I. | Q45998910 | ||
ApoE-/-Fas-/- C57BL/6 mice: a novel murine model simultaneously exhibits lupus nephritis, atherosclerosis, and osteopenia. | Q46014277 | ||
Regulation of renal lipid metabolism, lipid accumulation, and glomerulosclerosis in FVBdb/db mice with type 2 diabetes | Q46620651 | ||
Hypoxia, hypoxia-inducible transcription factor, and macrophages in human atherosclerotic plaques are correlated with intraplaque angiogenesis | Q46678597 | ||
Anti-inflammatory effects of short-term pioglitazone therapy in men with advanced diabetic nephropathy | Q46701051 | ||
A model for diabetic nephropathy: advantages of the inducible cAMP early repressor transgenic mouse over the streptozotocin-induced diabetic mouse. | Q46756941 | ||
Lipoprotein glomerulopathy induced by ApoE-Sendai is different from glomerular lesions in aged apoE-deficient mice | Q46810118 | ||
Type 3 hyperlipoproteinemia with mesangial foam cells in renal glomeruli | Q47868632 | ||
Transport of lipids from golgi to plasma membrane is defective in tangier disease patients and Abc1-deficient mice | Q47888259 | ||
Murine Model of Niemann-Pick C Disease: Mutation in a Cholesterol Homeostasis Gene | Q48047362 | ||
Baboon lecithin cholesterol acyltransferase (LCAT): cDNA sequences of two alleles, evolution, and gene expression | Q48114582 | ||
Chronic intermittent hypoxia is a major trigger for non-alcoholic fatty liver disease in morbid obese | Q48296229 | ||
Synthesis of apolipoprotein AI by peripheral tissues of the rooster. A possible mechanism of cellular cholesterol efflux. | Q50932756 | ||
Biosynthesis of apolipoprotein B in rooster kidney, intestine, and liver. | Q50941930 | ||
Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1. | Q51614218 | ||
Hypoxia and non-alcoholic fatty liver disease. | Q51922835 | ||
The NP-C gene: a key to pathways of intracellular cholesterol transport. | Q52213689 | ||
Targeted disruption of the mouse lecithin:cholesterol acyltransferase (LCAT) gene. Generation of a new animal model for human LCAT deficiency. | Q52524231 | ||
Protective effects of aliskiren and valsartan in mice with diabetic nephropathy. | Q53034300 | ||
Protective role of hypoxia-inducible factor-2alpha against ischemic damage and oxidative stress in the kidney. | Q53566907 | ||
Regulation of renal fatty acid and cholesterol metabolism, inflammation, and fibrosis in Akita and OVE26 mice with type 1 diabetes. | Q53602890 | ||
Apolipoprotein E in idiopathic nephrotic syndrome and focal segmental glomerulosclerosis. | Q53938164 | ||
Nlrp3 is a key modulator of diet-induced nephropathy and renal cholesterol accumulation. | Q54420633 | ||
Apolipoprotein E Sendai (arginine 145-->proline): a new variant associated with lipoprotein glomerulopathy | Q55670730 | ||
Bradykinin receptor 1 activation exacerbates experimental focal and segmental glomerulosclerosis | Q58007003 | ||
Hypoxia Converts Human Macrophages Into Triglyceride-Loaded Foam Cells | Q59487770 | ||
Membranoproliferative glomerulonephritis type II and Niemann-Pick disease type C | Q59619333 | ||
Acquired lecithin:cholesterol acyltransferase deficiency as a major factor in lowering plasma HDL levels in chronic kidney disease | Q60181971 | ||
Control of fatty acid metabolism in ischemic and hypoxic hearts | Q67342168 | ||
Receptor mediated uptake of apo B and apo E rich lipoproteins by human glomerular epithelial cells | Q68465915 | ||
Nephropathy of familial lecithin-cholesterol acyltransferase deficiency: report of a case | Q68858011 | ||
The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease | Q28141040 | ||
Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1 | Q28141056 | ||
Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosis | Q28145757 | ||
SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene | Q28264180 | ||
Hypoxia-inducible factors in the kidney | Q28303287 | ||
Renal cholesterol accumulation: a durable response after acute and subacute renal insults | Q28345329 | ||
Renal apolipoproteins in nephrotic rats | Q28378715 | ||
Receptor-mediated endocytosis of α-galactosidase A in human podocytes in Fabry disease | Q28477142 | ||
Cardiac defects and renal failure in mice with targeted mutations in Pkd2 | Q28510555 | ||
Unraveling the mechanisms of glomerular ultrafiltration: nephrin, a key component of the slit diaphragm | Q28611496 | ||
HIF-1alpha is essential for myeloid cell-mediated inflammation | Q29617581 | ||
Regulation of angiogenesis by hypoxia: role of the HIF system | Q29619187 | ||
Deficiency of a transcriptional regulator, inhibitor of differentiation 3, induces glomerulonephritis in apolipoprotein E-deficient mice: a model linking hyperlipidemia and renal disease | Q30425673 | ||
Differentiating between effects of streptozotocin per se and subsequent hyperglycemia on renal function and metabolism in the streptozotocin-diabetic rat model | Q31115333 | ||
HIF activation protects from acute kidney injury | Q33318643 | ||
Reverse cholesterol transport pathway in experimental chronic renal failure | Q33620325 | ||
Diabetes reduces the cholesterol exporter ABCA1 in mouse macrophages and kidneys | Q33901965 | ||
Effects of lowering LDL cholesterol on progression of kidney disease | Q33974663 | ||
Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport | Q34155049 | ||
A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis | Q34416768 | ||
Lipid abnormalities in the nephrotic syndrome: the therapeutic role of statins. | Q34499288 | ||
Plasma lipoproteins in familial lecithin: cholesterol acyltransferase deficiency. Further studies of very low and low density lipoprotein abnormalities | Q34503664 | ||
A novel apolipoprotein E mutation, E2 (Arg25Cys), in lipoprotein glomerulopathy | Q34504438 | ||
Etiological significance of apolipoprotein E mutations in lipoprotein glomerulopathy | Q34536516 | ||
Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis | Q34537191 | ||
Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression | Q34770083 | ||
Reversal of defective lysosomal transport in NPC disease ameliorates liver dysfunction and neurodegeneration in the npc1-/- mouse | Q34930699 | ||
Consequences of cellular cholesterol accumulation: basic concepts and physiological implications | Q34949033 | ||
Macrophage cholesterol homeostasis and metabolic diseases: critical role of cholesteryl ester mobilization | Q34992608 | ||
Characterization of Niemann-Pick Type C2 protein expression in multiple cancers using a novel NPC2 monoclonal antibody | Q35023240 | ||
Renal involvement in Neimann-Pick Disease | Q35573911 | ||
Molecular regulation of SREBP function: the Insig-SCAP connection and isoform-specific modulation of lipid synthesis | Q35723508 | ||
Experimental glomerulopathy alters renal cortical cholesterol, SR-B1, ABCA1, and HMG CoA reductase expression | Q35748843 | ||
Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels | Q35768439 | ||
Megalin knockout mice as an animal model of low molecular weight proteinuria. | Q35788270 | ||
Circulating TNF receptors 1 and 2 predict stage 3 CKD in type 1 diabetes | Q35804154 | ||
Circulating TNF receptors 1 and 2 predict ESRD in type 2 diabetes | Q35804201 | ||
Functional loss of ABCA1 in mice causes severe placental malformation, aberrant lipid distribution, and kidney glomerulonephritis as well as high-density lipoprotein cholesterol deficiency | Q35829385 | ||
Intercapillary Lesions in the Glomeruli of the Kidney | Q35875762 | ||
A 10-bp deletion in the apolipoprotein epsilon gene causing apolipoprotein E deficiency and severe type III hyperlipoproteinemia. | Q35881442 | ||
The pathology of Tangier disease. A light and electron microscopic study | Q35882676 | ||
HMG-CoA reductase activation and urinary pellet cholesterol elevations in acute kidney injury | Q35983550 | ||
Lipid accumulation of hypoxic tissue culture cells | Q36077757 | ||
Hypoxia signalling in cancer and approaches to enforce tumour regression | Q36488739 | ||
Lipids and the progression of renal disease | Q36600003 | ||
Renal failure in familial lecithin: cholesterol acyltransferase deficiency | Q36650673 | ||
Rodent models of streptozotocin-induced diabetic nephropathy | Q36820026 | ||
Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells | Q37011453 | ||
Serum concentrations of markers of TNFalpha and Fas-mediated pathways and renal function in nonproteinuric patients with type 1 diabetes. | Q37042111 | ||
Mechanisms of disease: the hypoxic tubular hypothesis of diabetic nephropathy | Q37082467 | ||
Cyclodextrin protects podocytes in diabetic kidney disease | Q37251166 | ||
Hypoxia-inducible factor 2 regulates hepatic lipid metabolism | Q37302297 | ||
Human immunodeficiency virus downregulates podocyte apoE expression | Q37337364 | ||
Pathogenic antibodies inhibit the binding of apolipoproteins to megalin/gp330 in passive Heymann nephritis | Q37374296 | ||
Cholesterol Contributes to Diabetic Nephropathy through SCAP-SREBP-2 Pathway | Q37392958 | ||
Lipid-protein interactions along the slit diaphragm of podocytes | Q37401685 | ||
Cyclodextrin overcomes deficient lysosome-to-endoplasmic reticulum transport of cholesterol in Niemann-Pick type C cells | Q37428937 | ||
Diabetes and diabetes-associated lipid abnormalities have distinct effects on initiation and progression of atherosclerotic lesions | Q37486465 | ||
A defect in cholesterol esterification in Niemann-Pick disease (type C) patients | Q37558069 | ||
Apolipoprotein E synthesis in human kidney, adrenal gland, and liver | Q37601028 | ||
Altered renal lipid metabolism and renal lipid accumulation in human diabetic nephropathy | Q37603244 | ||
Defective cholesterol trafficking in Niemann-Pick C-deficient cells | Q37736657 | ||
Lipid disorders and their relevance to outcomes in chronic kidney disease | Q37828035 | ||
Regulation of cholesterol and fatty acid synthesis | Q37866898 | ||
Lipid abnormalities in patients with chronic kidney disease | Q37882291 | ||
Cholesterol metabolism and the pathogenesis of non-alcoholic steatohepatitis | Q38064611 | ||
Up-regulation of gene expression by hypoxia is mediated predominantly by hypoxia-inducible factor 1 (HIF-1). | Q38326047 | ||
Interleukin-1β enhances the intracellular accumulation of cholesterol by up-regulating the expression of low-density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase in podocytes | Q38340229 | ||
Inflammatory stress exacerbates lipid accumulation in hepatic cells and fatty livers of apolipoprotein E knockout mice | Q39946599 | ||
P304 | page(s) | 169 | |
P577 | publication date | 2014-10-14 | |
P1433 | published in | Frontiers in Endocrinology | Q27723680 |
P1476 | title | Metabolism, energetics, and lipid biology in the podocyte - cellular cholesterol-mediated glomerular injury | |
P478 | volume | 5 |
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