scholarly article | Q13442814 |
P356 | DOI | 10.1074/JBC.M405100200 |
P698 | PubMed publication ID | 15272025 |
P2093 | author name string | Kenji Sobue | |
Ken'ichiro Hayashi | |||
Masahiro Watanabe | |||
Tsuyoshi Morita | |||
Kazuhiro Iwasaki | |||
Katsushi Shibata | |||
P2860 | cites work | Epiregulin as a major autocrine/paracrine factor released from ERK- and p38MAPK-activated vascular smooth muscle cells | Q24298549 |
Determination of Gab1 (Grb2-associated binder-1) interaction with insulin receptor-signaling molecules | Q24313281 | ||
Phosphorylation and regulation of Raf by Akt (protein kinase B) | Q28138863 | ||
The COOH-terminal tyrosine phosphorylation sites on IRS-1 bind SHP-2 and negatively regulate insulin signaling | Q28284128 | ||
Molecular and cellular aspects of the insulin-like growth factor I receptor | Q28288023 | ||
Systematic mapping of potential binding sites for Shc and Grb2 SH2 domains on insulin receptor substrate-1 and the receptors for insulin, epidermal growth factor, platelet-derived growth factor, and fibroblast growth factor | Q28615997 | ||
The protein tyrosine phosphatase SHP-2 negatively regulates ciliary neurotrophic factor induction of gene expression | Q28637904 | ||
Involvement of Src-homology/collagen (SHC) proteins in signaling through the insulin receptor and the insulin-like-growth-factor-I-receptor | Q28678384 | ||
Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases | Q29614338 | ||
Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases | Q29618331 | ||
Regulation of colony-stimulating factor 1 receptor signaling by the SH2 domain-containing tyrosine phosphatase SHPTP1 | Q30176913 | ||
Positive and negative regulation of Src-family membrane kinases by CD45. | Q33720532 | ||
Involvement of prolonged ras activation in thrombopoietin-induced megakaryocytic differentiation of a human factor-dependent hematopoietic cell line | Q33775054 | ||
The insulin-like growth factor axis: A review of atherosclerosis and restenosis | Q33832995 | ||
Regulation of receptor tyrosine kinase signaling by protein tyrosine phosphatases | Q33947049 | ||
Insulin-like growth factor-I and platelet-derived growth factor-BB induce directed migration of human arterial smooth muscle cells via signaling pathways that are distinct from those of proliferation | Q34133504 | ||
Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control | Q35057313 | ||
The "Gab" in signal transduction. | Q35082143 | ||
Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation | Q36667325 | ||
A dominant-negative mutant of mSOS1 inhibits insulin-induced Ras activation and reveals Ras-dependent and -independent insulin signaling pathways | Q40021572 | ||
Changes in the balance of phosphoinositide 3-kinase/protein kinase B (Akt) and the mitogen-activated protein kinases (ERK/p38MAPK) determine a phenotype of visceral and vascular smooth muscle cells | Q40953884 | ||
Osteogenic protein-1 and insulin-like growth factor I synergistically stimulate rat osteoblastic cell differentiation and proliferation | Q41088100 | ||
The IRS-signalling system during insulin and cytokine action | Q41516480 | ||
The phosphotyrosine phosphatase SHP-2 participates in a multimeric signaling complex and regulates T cell receptor (TCR) coupling to the Ras/mitogen-activated protein kinase (MAPK) pathway in Jurkat T cells | Q42971603 | ||
Phenotypic modulation of vascular smooth muscle cells induced by unsaturated lysophosphatidic acids | Q43696097 | ||
Regulation of insulin-like growth factor I receptor dephosphorylation by SHPS-1 and the tyrosine phosphatase SHP-2. | Q43847030 | ||
The novel role of the C-terminal region of SHP-2. Involvement of Gab1 and SHP-2 phosphatase activity in Elk-1 activation | Q43993755 | ||
Vascular remodeling induced by naturally occurring unsaturated lysophosphatidic acid in vivo | Q44592745 | ||
Platelet-derived growth factor-BB, insulin-like growth factor-I, and phorbol ester activate different signaling pathways for stimulation of vascular smooth muscle cell migration | Q47769116 | ||
Inhibition of vascular smooth muscle cell growth through antisense transcription of a rat insulin-like growth factor I receptor cDNA. | Q48073155 | ||
The mitogenic and myogenic actions of insulin-like growth factors utilize distinct signaling pathways. | Q52195728 | ||
Integrin-Associated Protein Binding Domain of Thrombospondin-1 Enhances Insulin-Like Growth Factor-I Receptor Signaling in Vascular Smooth Muscle Cells | Q57374813 | ||
P433 | issue | 39 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | phenotype | Q104053 |
preproinsulin | Q7240673 | ||
P304 | page(s) | 40807–40818 | |
P577 | publication date | 2004-09-24 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Insulin receptor substrate-1/SHP-2 interaction, a phenotype-dependent switching machinery of insulin-like growth factor-I signaling in vascular smooth muscle cells | |
P478 | volume | 279 |
Q35709811 | Cellular and Molecular Mechanisms of Phenotypic Switch in Gastrointestinal Smooth Muscle |
Q35640301 | Cooperative effects of Akt-1 and Raf-1 on the induction of cellular senescence in doxorubicin or tamoxifen treated breast cancer cells |
Q54466508 | Endothelial insulin-like growth factor-1 modulates proliferation and phenotype of smooth muscle cells induced by low shear stress. |
Q51922958 | Expression profiles of nestin in vascular smooth muscle cells in vivo and in vitro. |
Q90711245 | Hyperglycemia induces vascular smooth muscle cell dedifferentiation by suppressing insulin receptor substrate-1-mediated p53/KLF4 complex stabilization |
Q33855046 | Insulin-like growth factor-I-stimulated insulin receptor substrate-1 negatively regulates Src homology 2 domain-containing protein-tyrosine phosphatase substrate-1 function in vascular smooth muscle cells |
Q26827352 | Involvement of protein tyrosine phosphatases in adipogenesis: new anti-obesity targets? |
Q51158859 | Matrix metalloproteinase-2 expression by vascular smooth muscle cells is mediated by both stimulatory and inhibitory signals in response to growth factors. |
Q21131281 | Molecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advances |
Q34146262 | Molecular regulation of contractile smooth muscle cell phenotype: implications for vascular tissue engineering |
Q36862768 | Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response |
Q41714511 | Nuclear Import Mechanism for Myocardin Family Members and Their Correlation with Vascular Smooth Muscle Cell Phenotype |
Q35754163 | P-selectin activates integrin-mediated colon carcinoma cell adhesion to fibronectin |
Q35055601 | PDGF-induced vascular smooth muscle cell proliferation is associated with dysregulation of insulin receptor substrates |
Q91312846 | Prostaglandin D2 stimulates phenotypic changes in vascular smooth muscle cells |
Q46972339 | Rapamycin promotes vascular smooth muscle cell differentiation through insulin receptor substrate-1/phosphatidylinositol 3-kinase/Akt2 feedback signaling |
Q36870887 | Regulation and characteristics of vascular smooth muscle cell phenotypic diversity. |
Q30354532 | Regulation of vascular smooth muscle phenotype by cross-regulation of krüppel-like factors |
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Q37106652 | Role of the phosphatidylinositol-3-kinase and extracellular regulated kinase pathways in the induction of hypoxia-inducible factor (HIF)-1 activity and the HIF-1 target vascular endothelial growth factor in ovarian granulosa cells in response to fol |
Q34966603 | Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging |
Q37865381 | Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy. |
Q35925223 | Smooth muscle cell signal transduction: implications of vascular biology for vascular surgeons. |
Q36654406 | TIPE2 deficiency accelerates neointima formation by downregulating smooth muscle cell differentiation |
Q24563332 | The development and application of a quantitative peptide microarray based approach to protein interaction domain specificity space |
Q36246905 | The early- and late stages in phenotypic modulation of vascular smooth muscle cells: differential roles for lysophosphatidic acid |
Q37328039 | The influence of RGD-bearing hydrogels on the re-expression of contractile vascular smooth muscle cell phenotype |
Q33577586 | The role of Src homology 2 containing protein tyrosine phosphatase 2 in vascular smooth muscle cell migration and proliferation |
Q37837732 | Therapeutic resistance resulting from mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR signaling pathways. |
Q37551918 | β-Adrenergic Receptor and Insulin Resistance in the Heart |
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