Doxorubicin activates nuclear factor of activated T-lymphocytes and Fas ligand transcription: role of mitochondrial reactive oxygen species and calcium

scientific journal article

Doxorubicin activates nuclear factor of activated T-lymphocytes and Fas ligand transcription: role of mitochondrial reactive oxygen species and calcium is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1042/BJ20050285
P8608Fatcat IDrelease_iecxdswxwjcyvcrlb5sameob24
P3181OpenCitations bibliographic resource ID198864
P932PMC publication ID1175131
P698PubMed publication ID15799720
P5875ResearchGate publication ID7935748

P2093author name stringJoy Joseph
B. Kalyanaraman
Sonya Cunningham
Eugene A. Konorev
Eugene H. Kaji
Shasi V. Kalivendi
Sravan K. Vanamala
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Calcineurin signaling and NFAT activation in cardiovascular and skeletal muscle developmentQ33975200
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Doxorubicin-induced apoptosis: implications in cardiotoxicityQ34773776
Doxorubicin-induced cardiac mitochondrionopathyQ35217039
Participation of endoplasmic reticulum and mitochondrial calcium handling in apoptosis: more than just neighborhood?Q35785899
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Mitochondrial control of calcium-channel gating: a mechanism for sustained signaling and transcriptional activation in T lymphocytesQ37253977
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Role of iron in adriamycin biochemistryQ39745692
Mitochondrial dysfunction is an early indicator of doxorubicin-induced apoptosisQ40697544
Doxorubicin-induced apoptosis is associated with increased transcription of endothelial nitric-oxide synthase. Effect of antiapoptotic antioxidants and calciumQ40777736
Doxorubicin-induced apoptosis in human T-cell leukemia is mediated by caspase-3 activation in a Fas-independent way.Q41074621
Activation of nuclear factor-kappaB during doxorubicin-induced apoptosis in endothelial cells and myocytes is pro-apoptotic: the role of hydrogen peroxideQ41817128
Attenuation of drug-stimulated topoisomerase II-DNA cleavable complex formation in wild-type HL-60 cells treated with an intracellular calcium buffer is correlated with decreased cytotoxicity and site-specific hypophosphorylation of topoisomerase IIQ41999727
Early and delayed clinical cardiotoxicity of doxorubicinQ42225832
Reactive oxygen species regulate FLICE inhibitory protein (FLIP) and susceptibility to Fas-mediated apoptosis in cardiac myocytesQ42435182
Dose-dependent increase in sensitivity to calcium-induced mitochondrial dysfunction and cardiomyocyte cell injury by doxorubicinQ42554673
Expression of the NF-kappa B target gene IEX-1 (p22/PRG1) does not prevent cell death but instead triggers apoptosis in Hela cellsQ43539821
Interference with calcium-dependent mitochondrial bioenergetics in cardiac myocytes isolated from doxorubicin-treated ratsQ43709644
Inhibition of the cardiac mitochondrial calcium pump by adriamycin in vitroQ43992109
Carvedilol protects against doxorubicin-induced mitochondrial cardiomyopathyQ44260012
Tissue inhibitor of metalloproteinases-3 and matrix metalloproteinase-3 regulate neuronal sensitivity to doxorubicin-induced apoptosisQ44574077
Doxorubicin induces apoptosis in normal and tumor cells via distinctly different mechanisms. intermediacy of H(2)O(2)- and p53-dependent pathwaysQ44822086
Assay of ubiquinones and ubiquinols as antioxidantsQ46044980
Autocrine and paracrine apoptosis are mediated by differential regulation of Fas ligand activity in two distinct Jurkat T cell populationsQ48032499
Endothelial nitric oxide synthase-dependent superoxide generation from adriamycin.Q52527515
Adriamycin--an antitumor antibiotic in the treatment of neoplastic diseasesQ68663463
Pulse radiolysis studies of antitumor quinones: Radical lifetimes, reactivity with oxygen, and one-electron reduction potentialsQ70933229
One-electron reactions in biochemical systems as studied by pulse radiolysis. 3. UbiquinoneQ71495014
Hydrogen Peroxide Stimulates the Ca2+ Release Channel from Skeletal Muscle Sarcoplasmic ReticulumQ71823683
Drug-induced apoptosis is associated with enhanced Fas (Apo-1/CD95) ligand expression but occurs independently of Fas (Apo-1/CD95) signaling in human T-acute lymphatic leukemia cellsQ73622800
Two NFAT transcription factor binding sites participate in the regulation of CD95 (Fas) ligand expression in activated human T cellsQ73935008
Apoptosis in rat cardiac myocytes induced by Fas ligand: priming for Fas-mediated apoptosis with doxorubicinQ73975382
Doxorubicin-induced apoptosis in endothelial cells and cardiomyocytes is ameliorated by nitrone spin traps and ebselen. Role of reactive oxygen and nitrogen speciesQ74014516
Doxorubicin-induced cardiomyopathyQ77323607
P433issuePt 2
P407language of work or nameEnglishQ1860
P921main subjectdoxorubicinQ18936
mitochondrionQ39572
reactive oxygen speciesQ424361
lymphocyteQ715347
P304page(s)527–539
P577publication date2005-07-15
P1433published inBiochemical JournalQ864221
P1476titleDoxorubicin activates nuclear factor of activated T-lymphocytes and Fas ligand transcription: role of mitochondrial reactive oxygen species and calcium
P478volume389

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