Caspases and mitochondria in c-Myc-induced apoptosis: identification of ATM as a new target of caspases

scientific journal article

Caspases and mitochondria in c-Myc-induced apoptosis: identification of ATM as a new target of caspases is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1042514403
P356DOI10.1038/SJ.ONC.1203567
P698PubMed publication ID10822387
P5875ResearchGate publication ID12496427

P2093author name stringE. Hölttä
K. Järvinen
A. Hotti
P. Siivola
P2860cites workCytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascadeQ24311006
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53Q24311891
A single ataxia telangiectasia gene with a product similar to PI-3 kinaseQ24323579
Requirement for the CD95 receptor-ligand pathway in c-Myc-induced apoptosisQ24324204
Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3Q24324482
Cloning, expression, and chromosomal localization of the 140-kilodalton subunit of replication factor C from mice and humansQ24614099
Interaction between ATM protein and c-Abl in response to DNA damageQ28239339
Transactivation-defective c-MycS retains the ability to regulate proliferation and apoptosisQ28292481
A unique glucose-dependent apoptotic pathway induced by c-MycQ28575560
Enhanced phosphorylation of p53 by ATM in response to DNA damageQ28609838
Microfilament reorganization during apoptosis: the role of Gas2, a possible substrate for ICE-like proteasesQ28610808
The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin AQ28610837
Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosisQ28610843
Mitochondria and apoptosisQ29547905
Induction of apoptosis in fibroblasts by c-myc proteinQ29614346
Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalizationQ29614701
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasiaQ29615437
Caspases: killer proteasesQ29616315
Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiationQ29871427
Mechanisms of apoptosis by c-MycQ33667315
A mutant p53 antagonizes the deregulated c-myc-mediated enhancement of apoptosis and decrease in leukemogenicityQ33861971
Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.Q33887952
Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous systemQ34467644
c-Myc transactivation of LDH-A: implications for tumor metabolism and growthQ36238451
Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.Q36364876
DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosisQ36365577
Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic deathQ36366579
A functional role for death proteases in s-Myc- and c-Myc-mediated apoptosisQ36573712
Ornithine decarboxylase is a mediator of c-Myc-induced apoptosisQ36664688
A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteinsQ38295120
Cleavage and inactivation of ATM during apoptosis.Q38321497
Activation of an MDM2-specific caspase by p53 in the absence of apoptosisQ40954121
Caspase-9 can be activated without proteolytic processingQ40966257
Effects of wild-type and mutated p53 and Id proteins on the induction of apoptosis by adenovirus E1A, c-Myc, Bax, and Nip3 in p53 null mouse cerebellum cellsQ40970273
An anti-sense construct of full-length ATM cDNA imposes a radiosensitive phenotype on normal cellsQ41001847
Involvement of CPP32/Caspase-3 in c-Myc-induced apoptosisQ41064826
Recombinant ATM protein complements the cellular A-T phenotypeQ41099853
Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue BakQ41134694
Cdc25 cell-cycle phosphatase as a target of c-mycQ41175989
D4-GDI, a substrate of CPP32, is proteolyzed during Fas-induced apoptosisQ41199292
Mitochondrial control of apoptosisQ41339880
Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.Q41414258
p53 and ATM: cell cycle, cell death, and cancer.Q41438652
The many roles of c-Myc in apoptosisQ41748386
Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.Q53425055
Analysis of the membrane potential of rat- and mouse-liver mitochondria by flow cytometry and possible applications.Q54085818
A monoclonal antibody against a synthetic peptide reveals common structures among spectrins and alpha-actininQ69010004
Structural and functional analysis of poly(ADP ribose) polymerase: an immunological studyQ69029900
The central executioners of apoptosis: caspases or mitochondria?Q77135310
P433issue19
P407language of work or nameEnglishQ1860
P921main subjectmitochondrionQ39572
apoptotic processQ14599311
P304page(s)2354–2362
P577publication date2000-05-04
P1433published inOncogeneQ1568657
P1476titleCaspases and mitochondria in c-Myc-induced apoptosis: identification of ATM as a new target of caspases
P478volume19

Reverse relations

cites work (P2860)
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