Phospholipase C epsilon scaffolds to muscle-specific A kinase anchoring protein (mAKAPbeta) and integrates multiple hypertrophic stimuli in cardiac myocytes

scientific journal article

Phospholipase C epsilon scaffolds to muscle-specific A kinase anchoring protein (mAKAPbeta) and integrates multiple hypertrophic stimuli in cardiac myocytes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M111.231993
P8608Fatcat IDrelease_p32alutznbbeffyi44fv3lzcbu
P3181OpenCitations bibliographic resource ID3596645
P932PMC publication ID3123069
P698PubMed publication ID21550986

P50authorMichael S KapiloffQ56529035
P2093author name stringAlan V Smrcka
Sundeep Malik
Grant G Kelley
Lianghui Zhang
P2860cites workPhospholipase C epsilon modulates beta-adrenergic receptor-dependent cardiac contraction and inhibits cardiac hypertrophyQ46809282
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Insulin-like Growth Factor-I Rapidly Activates Multiple Signal Transduction Pathways in Cultured Rat Cardiac MyocytesQ57244774
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Myocyte hypertrophy in neonatal rat heart cultures and its regulation by serum and by catecholaminesQ72769145
PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing heartsQ22254160
A novel bifunctional phospholipase c that is regulated by Galpha 12 and stimulates the Ras/mitogen-activated protein kinase pathwayQ24290368
Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by RasQ24290369
mAKAP and the ryanodine receptor are part of a multi-component signaling complex on the cardiomyocyte nuclear envelopeQ24291765
The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways.Q24336212
Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5Q24561772
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An adenylyl cyclase-mAKAPbeta signaling complex regulates cAMP levels in cardiac myocytesQ28508445
G-protein-coupled receptor agonists activate endogenous phospholipase Cepsilon and phospholipase Cbeta3 in a temporally distinct mannerQ28564687
The mAKAP complex participates in the induction of cardiac myocyte hypertrophy by adrenergic receptor signalingQ28571079
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Nesprin-1alpha contributes to the targeting of mAKAP to the cardiac myocyte nuclear envelopeQ28582179
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Phospholipase Cepsilon is a nexus for Rho and Rap-mediated G protein-coupled receptor-induced astrocyte proliferationQ36024090
Enhanced Galphaq signaling: a common pathway mediates cardiac hypertrophy and apoptotic heart failureQ36286936
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Hormonal regulation of phospholipase Cepsilon through distinct and overlapping pathways involving G12 and Ras family G-proteinsQ41849600
Local InsP3-dependent perinuclear Ca2+ signaling in cardiac myocyte excitation-transcription couplingQ41919774
Epac and phospholipase Cepsilon regulate Ca2+ release in the heart by activation of protein kinase Cepsilon and calcium-calmodulin kinase II.Q42443922
Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. A paracrine mechanism for myocardial cell hypertrophyQ44207696
Ric-8 enhances G protein betagamma-dependent signaling in response to betagamma-binding peptides in intact cellsQ46414885
The alpha 1A-adrenergic receptor subtype mediates biochemical, molecular, and morphologic features of cultured myocardial cell hypertrophyQ46427210
P4510describes a project that usesImageJQ1659584
P433issue26
P407language of work or nameEnglishQ1860
P304page(s)23012-23021
P577publication date2011-05-05
P1433published inJournal of Biological ChemistryQ867727
P1476titlePhospholipase C epsilon scaffolds to muscle-specific A kinase anchoring protein (mAKAPbeta) and integrates multiple hypertrophic stimuli in cardiac myocytes
P478volume286