Antioxidant enzyme, 3-mercaptopyruvate sulfurtransferase-knockout mice exhibit increased anxiety-like behaviors: a model for human mercaptolactate-cysteine disulfiduria

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Antioxidant enzyme, 3-mercaptopyruvate sulfurtransferase-knockout mice exhibit increased anxiety-like behaviors: a model for human mercaptolactate-cysteine disulfiduria is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1024468959
P356DOI10.1038/SREP01986
P3181OpenCitations bibliographic resource ID2973507
P932PMC publication ID3680806
P698PubMed publication ID23759691
P5875ResearchGate publication ID237815875

P2093author name stringTakaaki Ito
Hidenori Suzuki
Noriyuki Nagahara
Masatoshi Nagano
Kenji Shimamura
Toshio Akimoto
P2860cites workMental Deficiency and a New AminoaciduriaQ52127000
3-Mercaptopyruvate sulfurtransferaseQ72030634
Beta mercaptolactate-cysteine disulfide: analog of cystine in the urine of a mentally retarded patientQ72033686
Beta-mercaptolactate-cysteine disulfide in the urine of a mentally retarded patientQ72493513
A point mutation in a silencer module reduces the promoter activity for the human mercaptopyruvate sulfurtransferaseQ80912932
Is novel signal transducer sulfur oxide involved in the redox cycle of persulfide at the catalytic site cysteine in a stable reaction intermediate of mercaptopyruvate sulfurtransferase?Q82846690
3-Mercaptopyruvate sulfurtransferase produces hydrogen sulfide and bound sulfane sulfur in the brainQ28513550
Thioredoxin-dependent enzymatic activation of mercaptopyruvate sulfurtransferase. An intersubunit disulfide bond serves as a redox switch for activationQ28567305
Tissue and subcellular distribution of mercaptopyruvate sulfurtransferase in the rat: confocal laser fluorescence and immunoelectron microscopic studies combined with biochemical analysisQ28569061
Cytosolic mercaptopyruvate sulfurtransferase is evolutionarily related to mitochondrial rhodanese. Striking similarity in active site amino acid sequence and the increase in the mercaptopyruvate sulfurtransferase activity of rhodanese by site-directQ28574862
Post-translational regulation of mercaptopyruvate sulfurtransferase via a low redox potential cysteine-sulfenate in the maintenance of redox homeostasisQ30859349
Conditional gene knockout using cre recombinaseQ33935863
Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolismQ34136356
Serotonin-1A autoreceptors are necessary and sufficient for the normal formation of circuits underlying innate anxietyQ35008700
Regulation of mercaptopyruvate sulfurtransferase activity via intrasubunit and intersubunit redox-sensing switchesQ38059256
Role of amino acid residues in the active site of rat liver mercaptopyruvate sulfurtransferase. CDNA cloning, overexpression, and site-directed mutagenesisQ38351941
A review of the clinical presentation and laboratory findings in two uncommon hereditary disorders of sulfur amino acid metabolism, beta-mercaptolactate cysteine disulfideuria and sulfite oxidase deficiencyQ39820017
Metabolism of sulfur-containing amino acids in a patient excreting β-mercaptolactate-cysteine disulfideQ42234302
β-mercaptolactate cysteine disulfiduria in two normal sisters. Isolation and characterization of β-mercaptolactate cysteine disulfideQ42234371
Sulfur amino acids as precursors of β-mercaptolactate-cysteine disulfide in human subjectsQ42237840
3-mercaptolactate cysteine disulfiduria: biochemical studies on affected and unaffected members of a familyQ42261429
A novel pathway for the production of hydrogen sulfide from D-cysteine in mammalian cellsQ44131370
Beta-mercaptolactate cysteine disulphiduria in a mentally retarded Scottish maleQ45264711
The possible role of hydrogen sulfide as an endogenous neuromodulator.Q46606180
The possible role of hydrogen sulfide as an endogenous smooth muscle relaxant in synergy with nitric oxide.Q46738154
Early intervention with fluoxetine reverses abnormalities in the serotonergic system and behavior of rats exposed prenatally to dexamethasoneQ48468880
P275copyright licenseCreative Commons Attribution-NonCommercial-NoDerivs 3.0 UnportedQ19125045
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectknockout mouseQ1364740
Mercaptopyruvate sulfurtransferaseQ21991842
P304page(s)1986
P577publication date2013-01-01
P1433published inScientific ReportsQ2261792
P1476titleAntioxidant enzyme, 3-mercaptopyruvate sulfurtransferase-knockout mice exhibit increased anxiety-like behaviors: a model for human mercaptolactate-cysteine disulfiduria
P478volume3

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cites work (P2860)
Q416205013-Mercaptopyruvate sulfurtransferase produces potential redox regulators cysteine- and glutathione-persulfide (Cys-SSH and GSSH) together with signaling molecules H2S2, H2S3 and H2S.
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Q86881581CD47-dependent regulation of H₂S biosynthesis and signaling in T cells
Q89575848Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase
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Q89509540Increased Urinary 3-Mercaptolactate Excretion and Enhanced Passive Systemic Anaphylaxis in Mice Lacking Mercaptopyruvate Sulfurtransferase, a Model of Mercaptolactate-Cysteine Disulfiduria
Q36946554Modular transcriptional repertoire and MicroRNA target analyses characterize genomic dysregulation in the thymus of Down syndrome infants
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Q91742333Novel Characterization of Antioxidant Enzyme, 3-Mercaptopyruvate Sulfurtransferase-Knockout Mice: Overexpression of the Evolutionarily-Related Enzyme Rhodanese
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