| scholarly article | Q13442814 |
| P50 | author | Antony Giuseppe Galione | Q24005240 |
| Lianne C Davis | Q59825997 | ||
| Edith Sim | Q87441182 | ||
| Frances Platt | Q53912631 | ||
| David G Russell | Q56223852 | ||
| P2093 | author name string | Gurdyal S Besra | |
| Anthony J Morgan | |||
| Michael B Brenner | |||
| Ann Williams | |||
| Daniel S Ory | |||
| Doris Höglinger | |||
| Emyr Lloyd-Evans | |||
| Evgeniya Nazarova | |||
| Ian M Williams | |||
| Nada Al Eisa | |||
| Nathan A Lack | |||
| Nick Platt | |||
| Patricia Tynan | |||
| Paul Fineran | |||
| Raju Venkata V Tatituri | |||
| Simon Clark | |||
| P2860 | cites work | Chronic cyclodextrin treatment of murine Niemann-Pick C disease ameliorates neuronal cholesterol and glycosphingolipid storage and disease progression | Q21142752 |
| Niemann-Pick disease type C | Q21202883 | ||
| Identification of HE1 as the second gene of Niemann-Pick C disease | Q24290663 | ||
| NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes | Q24310567 | ||
| Ebola virus entry requires the cholesterol transporter Niemann-Pick C1 | Q24329246 | ||
| Tuberculosis toxin blocking phagosome maturation inhibits a novel Ca2+/calmodulin-PI3K hVPS34 cascade | Q24672714 | ||
| Characterization of a Carbon-Carbon Hydrolase from Mycobacterium tuberculosis Involved in Cholesterol Metabolism | Q27658021 | ||
| Structural Insights into the Niemann-Pick C1 (NPC1)-Mediated Cholesterol Transfer and Ebola Infection | Q27706522 | ||
| Transmembrane molecular pump activity of Niemann-Pick C1 protein | Q28140887 | ||
| Cutting edge: Mycobacterium tuberculosis blocks Ca2+ signaling and phagosome maturation in human macrophages via specific inhibition of sphingosine kinase | Q28181855 | ||
| Foamy macrophages and the progression of the human tuberculosis granuloma | Q28255669 | ||
| Phagosome-lysosome fusion is a calcium-independent event in macrophages | Q28273718 | ||
| Pathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosis | Q28302775 | ||
| Mycolic acid modification by the mmaA4 gene of M. tuberculosis modulates IL-12 production | Q28472837 | ||
| Cyclodextrin induces calcium-dependent lysosomal exocytosis | Q28476365 | ||
| Mycobacterium tuberculosis controls host innate immune activation through cyclopropane modification of a glycolipid effector molecule | Q28486490 | ||
| Mycobacterial persistence requires the utilization of host cholesterol | Q28487070 | ||
| Autophagy in Niemann-Pick C disease is dependent upon Beclin-1 and responsive to lipid trafficking defects | Q28590485 | ||
| Genetic evidence for nonredundant functional cooperativity between NPC1 and NPC2 in lipid transport | Q28594812 | ||
| Lack of acidification in Mycobacterium phagosomes produced by exclusion of the vesicular proton-ATPase | Q29617355 | ||
| Mycobacterium tuberculosis phagosome maturation arrest: selective targeting of PI3P-dependent membrane trafficking. | Q30333276 | ||
| Tuberculosis and HIV coinfection | Q30427838 | ||
| Improved orange and red Ca²± indicators and photophysical considerations for optogenetic applications | Q30540842 | ||
| Trafficking and release of mycobacterial lipids from infected macrophages | Q73511680 | ||
| Roles of calcium and annexins in phagocytosis and elimination of an attenuated strain of Mycobacterium tuberculosis in human neutrophils | Q74587917 | ||
| Preparation of cell-wall fractions from mycobacteria | Q77914557 | ||
| Lysosomal storage diseases as disorders of autophagy | Q79827971 | ||
| Delay of phagosome maturation by a mycobacterial lipid is reversed by nitric oxide | Q44676853 | ||
| Trehalose is required for growth of Mycobacterium smegmatis | Q44854772 | ||
| Treatment with miglustat reverses the lipid-trafficking defect in Niemann-Pick disease type C. | Q44985264 | ||
| Analysis of fluorescently labeled glycosphingolipid-derived oligosaccharides following ceramide glycanase digestion and anthranilic acid labeling | Q44987271 | ||
| Cholesteroid nature of free mycolic acids from M. tuberculosis. | Q46723751 | ||
| Characterization of the tuberculous granuloma in murine and human lungs: cellular composition and relative tissue oxygen tension | Q46915063 | ||
| Mycobacterium avium- and Mycobacterium tuberculosis-containing vacuoles are dynamic, fusion-competent vesicles that are accessible to glycosphingolipids from the host cell plasmalemma | Q50195579 | ||
| Broad screening test for sphingolipid-storage diseases. | Q52174471 | ||
| FluoQ: a tool for rapid analysis of multiparameter fluorescence imaging data applied to oscillatory events. | Q30657065 | ||
| Response of cultured macrophages to Mycobacterium tuberculosis, with observations on fusion of lysosomes with phagosomes | Q31154479 | ||
| Direct molecular mass determination of trehalose monomycolate from 11 species of mycobacteria by MALDI-TOF mass spectrometry | Q33214678 | ||
| The Delta fbpA mutant derived from Mycobacterium tuberculosis H37Rv has an enhanced susceptibility to intracellular antimicrobial oxidative mechanisms, undergoes limited phagosome maturation and activates macrophages and dendritic cells | Q33318121 | ||
| Foamy macrophages from tuberculous patients' granulomas constitute a nutrient-rich reservoir for M. tuberculosis persistence | Q33383817 | ||
| Miglustat in adult and juvenile patients with Niemann-Pick disease type C: long-term data from a clinical trial | Q33444755 | ||
| MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis | Q33466750 | ||
| Lipid changes in Niemann-Pick disease type C brain: personal experience and review of the literature | Q33607709 | ||
| Structure-function relationships of the antigenicity of mycolic acids in tuberculosis patients. | Q33704609 | ||
| Contribution of the Mycobacterium tuberculosis MmpL protein family to virulence and drug resistance | Q33788015 | ||
| Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism | Q34033091 | ||
| Cord factor trehalose 6,6'-dimycolate (TDM) mediates trafficking events during mycobacterial infection of murine macrophages | Q34220450 | ||
| Survival of mycobacteria in macrophages is mediated by coronin 1-dependent activation of calcineurin | Q34651109 | ||
| Miglustat for treatment of Niemann-Pick C disease: a randomised controlled study | Q34661485 | ||
| N-butyldeoxynojirimycin is a novel inhibitor of glycolipid biosynthesis. | Q34727425 | ||
| Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium | Q34866369 | ||
| Trehalose 6,6'-dimycolate and lipid in the pathogenesis of caseating granulomas of tuberculosis in mice. | Q35088102 | ||
| SQ109 targets MmpL3, a membrane transporter of trehalose monomycolate involved in mycolic acid donation to the cell wall core of Mycobacterium tuberculosis | Q35867500 | ||
| Miglustat improves purkinje cell survival and alters microglial phenotype in feline Niemann-Pick disease type C. | Q35960437 | ||
| Identification of NPC1 as the target of U18666A, an inhibitor of lysosomal cholesterol export and Ebola infection | Q36479650 | ||
| Intracellular sphingosine releases calcium from lysosomes | Q36552660 | ||
| Intracellular Mycobacterium tuberculosis exploits host-derived fatty acids to limit metabolic stress | Q36666086 | ||
| Clues to the mechanism of cholesterol transfer from the structure of NPC1 middle lumenal domain bound to NPC2. | Q37247724 | ||
| Relative acidic compartment volume as a lysosomal storage disorder-associated biomarker | Q37602227 | ||
| Lipids on trial: the search for the offending metabolite in Niemann-Pick type C disease | Q37671032 | ||
| Molecular mechanisms of endolysosomal Ca2+ signalling in health and disease | Q37944859 | ||
| Towards understanding the functional diversity of cell wall mycolic acids of Mycobacterium tuberculosis | Q38015657 | ||
| Recognition of the mycobacterial cord factor by Mincle: relevance for granuloma formation and resistance to tuberculosis | Q38077188 | ||
| Preventive vaccines for tuberculosis | Q38100044 | ||
| Impaired antibacterial autophagy links granulomatous intestinal inflammation in Niemann-Pick disease type C1 and XIAP deficiency with NOD2 variants in Crohn's disease | Q39940199 | ||
| Simultaneous quantitative analysis of ceramide and sphingosine in mouse blood by naphthalene-2,3-dicarboxyaldehyde derivatization after hydrolysis with ceramidase | Q40433898 | ||
| MmpL genes are associated with mycolic acid metabolism in mycobacteria and corynebacteria | Q42189366 | ||
| Niemann-pick type C1 (NPC1) overexpression alters cellular cholesterol homeostasis | Q42492641 | ||
| Weekly cyclodextrin administration normalizes cholesterol metabolism in nearly every organ of the Niemann-Pick type C1 mouse and markedly prolongs life. | Q42704514 | ||
| Miglustat in patients with Niemann-Pick disease Type C (NP-C): a multicenter observational retrospective cohort study | Q43298156 | ||
| Inhibition of the SERCA Ca2+ pumps by curcumin. Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP. | Q43815503 | ||
| Cyclodextrins in the treatment of a mouse model of Niemann-Pick C disease | Q43852274 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P4510 | describes a project that uses | ggplot2 | Q326489 |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 18 | |
| P577 | publication date | 2016-11-18 | |
| P1433 | published in | Wellcome Open Research | Q28559076 |
| P1476 | title | Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway | |
| P478 | volume | 1 |
| Q93270326 | Analyzing the impact of Mycobacterium tuberculosis infection on primary human macrophages by combined exploratory and targeted metabolomics |
| Q50146160 | Crohn's Disease in Niemann-Pick Disease Type C1: Caught in the Cross-Fire of Host-Microbial Interactions |
| Q36336273 | Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti-tubercular agents using a fragment-based drug design approach |
| Q57060151 | Lysosomal storage diseases |
| Q52729770 | Mitochondria-associated ER membranes (MAMs) and lysosomal storage diseases. |
| Q64103898 | Oxidized low-density lipoprotein (oxLDL) supports Mycobacterium tuberculosis survival in macrophages by inducing lysosomal dysfunction |
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