| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M003180200 |
| P698 | PubMed publication ID | 10964915 |
| P2093 | author name string | Srivastava K | |
| Traub LM | |||
| Schaffer JE | |||
| Ory DS | |||
| Millard EE | |||
| P2860 | cites work | Niemann-Pick C1 protein: obligatory roles for N-terminal domains and lysosomal targeting in cholesterol mobilization | Q22008745 |
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| Localization of Niemann-Pick C1 protein in astrocytes: implications for neuronal degeneration in Niemann- Pick type C disease | Q24672011 | ||
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| The Niemann-Pick C1 protein resides in a vesicular compartment linked to retrograde transport of multiple lysosomal cargo | Q33856244 | ||
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| Isolation and characterization of Chinese hamster ovary cell mutants defective in intracellular low density lipoprotein-cholesterol trafficking | Q36222559 | ||
| A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes | Q37251604 | ||
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| Polyunsaturated fatty acids decrease expression of promoters with sterol regulatory elements by decreasing levels of mature sterol regulatory element-binding protein | Q41007059 | ||
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| Substitution of alanine for serine 250 in the murine fatty acid transport protein inhibits long chain fatty acid transport | Q42825339 | ||
| Role of Niemann-Pick type C1 protein in intracellular trafficking of low density lipoprotein-derived cholesterol | Q47887125 | ||
| Murine Model of Niemann-Pick C Disease: Mutation in a Cholesterol Homeostasis Gene | Q48047362 | ||
| ??? | Q22254154 | ||
| P433 | issue | 49 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | overexpression | Q61643320 |
| P1104 | number of pages | 7 | |
| P304 | page(s) | 38445-38451 | |
| P577 | publication date | 2000-12-01 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Niemann-pick type C1 (NPC1) overexpression alters cellular cholesterol homeostasis | |
| P478 | volume | 275 |
| Q36973175 | A Single Residue in Ebola Virus Receptor NPC1 Influences Cellular Host Range in Reptiles |
| Q35649458 | A murine Niemann-Pick C1 I1061T knock-in model recapitulates the pathological features of the most prevalent human disease allele |
| Q40665899 | Accumulation of tyrosinase in the endolysosomal compartment is induced by U18666A. |
| Q28509055 | Altered cholesterol homeostasis in cultured and in vivo models of cystic fibrosis |
| Q30617345 | Assessing cholesterol storage in live cells and C. elegans by stimulated Raman scattering imaging of phenyl-Diyne cholesterol |
| Q37487196 | Binding between the Niemann-Pick C1 protein and a photoactivatable cholesterol analog requires a functional sterol-sensing domain |
| Q40067585 | Biochemical Basis for Increased Activity of Ebola Glycoprotein in the 2013-16 Epidemic |
| Q37388778 | Box C/D small nucleolar RNA (snoRNA) U60 regulates intracellular cholesterol trafficking. |
| Q37415602 | Characterization of cholesterol homeostasis in telomerase-immortalized Tangier disease fibroblasts reveals marked phenotype variability. |
| Q46231289 | Characterization of fluorescent sterol binding to purified human NPC1. |
| Q40282596 | Chinese hamster ovary cell lines selected for resistance to ebolavirus glycoprotein mediated infection are defective for NPC1 expression. |
| Q24650803 | Cholesterol depletion results in site-specific increases in epidermal growth factor receptor phosphorylation due to membrane level effects. Studies with cholesterol enantiomers |
| Q39426368 | Cholesterol depletion with (2-hydroxypropyl)- β-cyclodextrin modifies the gating of membrane electroporation-induced inward current in pituitary tumor GH3 cells: experimental and analytical studies |
| Q43746994 | Cholesterol overload promotes morphogenesis of a Niemann-Pick C (NPC)-like compartment independent of inhibition of NPC1 or HE1/NPC2 function |
| Q35205918 | Cholesterol oxidation products are sensitive and specific blood-based biomarkers for Niemann-Pick C1 disease |
| Q33417684 | Cholesterol-dependent anaplasma phagocytophilum exploits the low-density lipoprotein uptake pathway |
| Q38326346 | Cholesterol-dependent lipid assemblies regulate the activity of the ecto-nucleotidase CD39. |
| Q24644759 | Deficiency of niemann-pick type C-1 protein impairs release of human immunodeficiency virus type 1 and results in Gag accumulation in late endosomal/lysosomal compartments |
| Q96111679 | Detrimental effect of zwitterionic buffers on lysosomal homeostasis in cell lines and iPSC-derived neurons |
| Q90637917 | Disease-associated mutations in Niemann-Pick type C1 alter ER calcium signaling and neuronal plasticity |
| Q57371939 | Fate of Endogenously Synthesized Cholesterol in Niemann-Pick Type C1 Cells |
| Q33756859 | Fluorescent imaging of Cl- in Amphiuma red blood cells: how the nuclear exclusion of Cl- affects the plasma membrane potential |
| Q52585959 | High-content screen for modifiers of Niemann-Pick Type C disease in patient cells. |
| Q38716617 | Histone deacetylase inhibitors correct the cholesterol storage defect in most Niemann-Pick C1 mutant cells. |
| Q101222456 | Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells |
| Q38315736 | Impaired autophagy in the lipid-storage disorder Niemann-Pick type C1 disease |
| Q90058197 | Individualized management of genetic diversity in Niemann-Pick C1 through modulation of the Hsp70 chaperone system |
| Q33721375 | Interaction of functional NPC1gene Polymorphism with smoking on coronary heart disease |
| Q36852328 | Lipid rafts: dream or reality for cholesterol transporters? |
| Q36208265 | Loss of Cathepsin B and L Leads to Lysosomal Dysfunction, NPC-Like Cholesterol Sequestration and Accumulation of the Key Alzheimer's Proteins |
| Q92460235 | Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export |
| Q34060766 | Modulation of cellular cholesterol transport and homeostasis by Rab11. |
| Q35089442 | Molecular characterization of the detergent-insoluble cholesterol-rich membrane microdomain (raft) of the central nervous system |
| Q34354334 | Multidrug permeases and subcellular cholesterol transport |
| Q28593527 | Mutation in EGFP domain of LDL receptor-related protein 6 impairs cellular LDL clearance |
| Q24300768 | NPC1 and NPC2 Regulate Cellular Cholesterol Homeostasis through Generation of Low Density Lipoprotein Cholesterol-derived Oxysterols |
| Q28590002 | NPC2 is expressed in human and murine liver and secreted into bile: potential implications for body cholesterol homeostasis |
| Q34104368 | Niemann-Pick C1 affects the gene delivery efficacy of degradable polymeric nanoparticles |
| Q33717702 | Niemann-Pick C1 functions independently of Niemann-Pick C2 in the initial stage of retrograde transport of membrane-impermeable lysosomal cargo |
| Q24655769 | Niemann-Pick C1 protects against atherosclerosis in mice via regulation of macrophage intracellular cholesterol trafficking |
| Q64912185 | Niemann-Pick Type C Disease Reveals a Link between Lysosomal Cholesterol and PtdIns(4,5)P2 That Regulates Neuronal Excitability. |
| Q43089343 | Niemann-Pick type C1 I1061T mutant encodes a functional protein that is selected for endoplasmic reticulum-associated degradation due to protein misfolding |
| Q34974271 | PKC activation in Niemann pick C1 cells restores subcellular cholesterol transport |
| Q28585671 | Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway |
| Q24673502 | Pregnane X receptor (PXR) activation: a mechanism for neuroprotection in a mouse model of Niemann-Pick C disease |
| Q91173541 | Quantitating the epigenetic transformation contributing to cholesterol homeostasis using Gaussian process |
| Q39732986 | Reduction of TMEM97 increases NPC1 protein levels and restores cholesterol trafficking in Niemann-pick type C1 disease cells |
| Q40402188 | Silencing of the mutant SCAP allele accounts for restoration of a normal phenotype in CT60 cells selected for NPC1 expression |
| Q24329155 | Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection |
| Q51801566 | Sterol, protein and lipid trafficking in Chinese hamster ovary cells with Niemann-Pick type C1 defect. |
| Q40503180 | Systemic AAV9 gene therapy improves the lifespan of mice with Niemann-Pick disease, type C1. |
| Q21131381 | TIM-family proteins promote infection of multiple enveloped viruses through virion-associated phosphatidylserine |
| Q28245167 | Targeted mutation of the MLN64 START domain causes only modest alterations in cellular sterol metabolism |
| Q28208268 | Telomerase immortalization upregulates Rab9 expression and restores LDL cholesterol egress from Niemann-Pick C1 late endosomes |
| Q46960355 | The lipoprotein receptor-related protein-1 (LRP) adapter protein GULP mediates trafficking of the LRP ligand prosaposin, leading to sphingolipid and free cholesterol accumulation in late endosomes and impaired efflux |
| Q44655985 | The steroidal analog GW707 activates the SREBP pathway through disruption of intracellular cholesterol trafficking |
| Q46502947 | The sterol-sensing domain of the Niemann-Pick C1 (NPC1) protein regulates trafficking of low density lipoprotein cholesterol |
| Q33676201 | Tracking the subcellular fate of 20(s)-hydroxycholesterol with click chemistry reveals a transport pathway to the Golgi |
| Q44700086 | Transcriptomic classification of antitumor agents: application to the analysis of the antitumoral effect of SR31747A. |
| Q34866329 | Triglyceride accumulation protects against fatty acid-induced lipotoxicity |
| Q38470215 | Using SILAC proteomics to investigate the effect of the mycotoxin, alternariol, in the human H295R steroidogenesis model. |
| Q35685200 | snoRNA U17 regulates cellular cholesterol trafficking. |
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