Loss of R2D2 proteins ROPN1 and ROPN1L causes defects in murine sperm motility, phosphorylation, and fibrous sheath integrity

scientific journal article

Loss of R2D2 proteins ROPN1 and ROPN1L causes defects in murine sperm motility, phosphorylation, and fibrous sheath integrity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1095/BIOLREPROD.112.105262
P8608Fatcat IDrelease_ehmdbgtncfcdhnte35hjnbfclu
P932PMC publication ID4434999
P698PubMed publication ID23303679
P5875ResearchGate publication ID234099339

P2093author name stringSrinivasan Vijayaraghavan
Tejasvi Dudiki
Daniel W. Carr
Sarah E. Fiedler
P2860cites workAssociation of sperm protein 17 with A-kinase anchoring protein 3 in flagellaQ21245564
Identification of sperm-specific proteins that interact with A-kinase anchoring proteins in a manner similar to the type II regulatory subunit of PKAQ24291035
CABYR, a novel calcium-binding tyrosine phosphorylation-regulated fibrous sheath protein involved in capacitationQ24292237
CABYR isoforms expressed in late steps of spermiogenesis bind with AKAPs and ropporin in mouse sperm fibrous sheathQ24297094
A yeast two-hybrid system using Sp17 identified Ropporin as a novel cancer-testis antigen in hematologic malignanciesQ24307899
Protein kinase A RII-like (R2D2) proteins exhibit differential localization and AKAP interactionQ24323127
Association of the type II cAMP-dependent protein kinase with a human thyroid RII-anchoring protein. Cloning and characterization of the RII-binding domainQ24336977
Characterization of two non-testis-specific CABYR variants that bind to GSK3beta with a proline-rich extensin-like domainQ28115140
A-kinase anchoring protein 4 binding proteins in the fibrous sheath of the sperm flagellumQ28212220
AMY-1 interacts with S-AKAP84 and AKAP95 in the cytoplasm and the nucleus, respectively, and inhibits cAMP-dependent protein kinase activity by preventing binding of its catalytic subunit to A-kinase-anchoring protein (AKAP) complexQ28213025
Docking interactions in protein kinase and phosphatase networksQ28271644
Interaction of the regulatory subunit (RII) of cAMP-dependent protein kinase with RII-anchoring proteins occurs through an amphipathic helix binding motifQ28286420
Loss of ASP but not ROPN1 reduces mammalian ciliary motilityQ28506133
Multiple glycolytic enzymes are tightly bound to the fibrous sheath of mouse spermatozoaQ28508230
Fibrous sheath of mammalian spermatozoaQ28574746
FSCB, a novel protein kinase A-phosphorylated calcium-binding protein, is a CABYR-binding partner involved in late steps of fibrous sheath biogenesisQ28587064
Changes in intracellular distribution and activity of protein phosphatase PP1gamma2 and its regulating proteins in spermatozoa lacking AKAP4Q28590433
Glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme, is required for sperm motility and male fertilityQ28594144
Ropporin, a sperm-specific binding protein of rhophilin, that is localized in the fibrous sheath of sperm flagellaQ28613416
FSP95, a testis-specific 95-kilodalton fibrous sheath antigen that undergoes tyrosine phosphorylation in capacitated human spermatozoaQ30304394
CABYR binds to AKAP3 and Ropporin in the human sperm fibrous sheathQ30417189
Disruption and sequence identification of 2,000 genes in mouse embryonic stem cellsQ32066435
Cancer testis antigen vaccination affords long-term protection in a murine model of ovarian cancer.Q33582300
A re-evaluation of sperm protein 17 (Sp17) indicates a regulatory role in an A-kinase anchoring protein complex, rather than a unique role in sperm-zona pellucida bindingQ34170881
Sequence of a Rabbit Sperm Zona Pellucida Binding Protein and Localization during the Acrosome ReactionQ34292728
Capacitation of mouse spermatozoa. I. Correlation between the capacitation state and protein tyrosine phosphorylationQ34310197
Ontogeny of tyrosine phosphorylation-signaling pathways during spermatogenesis and epididymal maturation in the mouse.Q34540631
Domains, motifs, and scaffolds: the role of modular interactions in the evolution and wiring of cell signaling circuits.Q36498348
PKA, germ cells, and fertilityQ36731995
Proteomic changes in mammalian spermatozoa during epididymal maturationQ36859028
The scaffold role of the fibrous sheath.Q36888693
The biology of infertility: research advances and clinical challengesQ37206451
Molecular genetic analysis of two human sperm fibrous sheath proteins, AKAP4 and AKAP3, in men with dysplasia of the fibrous sheathQ38303614
Gene deletions in an infertile man with sperm fibrous sheath dysplasiaQ40410705
Protein kinase A-anchoring inhibitor peptides arrest mammalian sperm motilityQ42529103
Impact of epididymal maturation on the tyrosine phosphorylation patterns exhibited by rat spermatozoa.Q43586249
Activation of protein kinase A during human sperm capacitation and acrosome reactionQ44107327
Rapid PKA-catalysed phosphorylation of boar sperm proteins induced by the capacitating agent bicarbonateQ44736434
The development of signal transduction pathways during epididymal maturation is calcium dependent.Q44805440
Bicarbonate-induced phosphorylation of p270 protein in mouse sperm by cAMP-dependent protein kinaseQ46689519
Identification and characterization of RHOA-interacting proteins in bovine spermatozoaQ46956594
Sperm protein 17 is expressed in human somatic ciliated epithelia.Q47915307
Targeted disruption of the Akap4 gene causes defects in sperm flagellum and motility.Q52116313
Deletion of type IIalpha regulatory subunit delocalizes protein kinase A in mouse sperm without affecting motility or fertilization.Q52536028
Fluorescence in situ hybridization and molecular studies in infertile men with dysplasia of the fibrous sheath.Q54654563
Isolation and Characterization of the Fibrous Sheath of Rat Epididymal Spermatozoa1Q67460978
Sperm motility development in the epididymis is associated with decreased glycogen synthase kinase-3 and protein phosphatase 1 activityQ71602626
Immunolocalization of sperm protein 17 in human testis and ejaculated spermatozoaQ73817752
A description of spermiogenesis in the mouse and its use in analysis of the cycle of the seminiferous epithelium and germ cell renewalQ74409471
FSCB phosphorylation in mouse spermatozoa capacitationQ84837146
P4510describes a project that usesImageJQ1659584
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectphosphorylationQ242736
Ropporin 1-likeQ21988018
Ropporin, rhophilin associated protein 1Q21988019
sperm motilityQ27116486
P304page(s)41
P577publication date2013-02-01
P1433published inBiology of ReproductionQ4915061
P1476titleLoss of R2D2 proteins ROPN1 and ROPN1L causes defects in murine sperm motility, phosphorylation, and fibrous sheath integrity
P478volume88

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cites work (P2860)
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Q33698622Comparative Sperm Proteomics in Mouse Species with Divergent Mating Systems
Q41660919Determination of Highly Sensitive Biological Cell Model Systems to Screen BPA-Related Health Hazards Using Pathway Studio
Q28534807Dissociation between AKAP3 and PKARII promotes AKAP3 degradation in sperm capacitation
Q38652018Expression of uncharacterized male germ cell-specific genes and discovery of novel sperm-tail proteins in mice.
Q33112270FSCB phosphorylation regulates mouse spermatozoa capacitation through suppressing SUMOylation of ROPN1/ROPN1L.
Q38973718Functional anatomy of the mammalian sperm flagellum
Q61118461Loss-of-function mutations in QRICH2 cause male infertility with multiple morphological abnormalities of the sperm flagella
Q99710902Novel targets identified by integrated proteomic and phosphoproteomic analysis in spermatogenesis of swamp buffalo (Bubalus bubalis)
Q89699460Population-specific, recent positive directional selection suggests adaptation of human male reproductive genes to different environmental conditions
Q91872147Proteomic Changes in Human Sperm During Sequential in vitro Capacitation and Acrosome Reaction
Q38447411Spermatogenesis-associated proteins at different developmental stages of buffalo testicular seminiferous tubules identified by comparative proteomic analysis
Q37108824Studies in experimental autoimmune encephalomyelitis do not support developmental bisphenol a exposure as an environmental factor in increasing multiple sclerosis risk.
Q30580167Targeted NGS gene panel identifies mutations in RSPH1 causing primary ciliary dyskinesia and a common mechanism for ciliary central pair agenesis due to radial spoke defects.
Q58093176The protein phosphatase isoform PP1γ1 substitutes for PP1γ2 to support spermatogenesis but not normal sperm function and fertility
Q35932960Transketolase-like 1 ectopic expression is associated with DNA hypomethylation and induces the Warburg effect in melanoma cells.

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