| scholarly article | Q13442814 |
| P2093 | author name string | V. Palma | |
| T. Sun | |||
| H. Weiner | |||
| A. Ruiz i Altaba | |||
| P. Sánchez | |||
| M. Beyna | |||
| N. Dahmane | |||
| Y. Gitton | |||
| P433 | issue | 24 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | brain | Q1073 |
| Sonic hedgehog | Q14860215 | ||
| P304 | page(s) | 5201–5212 | |
| P577 | publication date | 2001-12-01 | |
| P1433 | published in | Development | Q3025404 |
| P1476 | title | The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis | |
| P478 | volume | 128 |
| Q37109670 | A GLI1-p53 inhibitory loop controls neural stem cell and tumour cell numbers |
| Q42057382 | A direct cross-talk between interferon-gamma and sonic hedgehog signaling that leads to the proliferation of neuronal precursor cells |
| Q37249645 | A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway |
| Q34928908 | A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors |
| Q64233929 | Abnormal activity of transcription factors gli in high-grade gliomas |
| Q40125376 | Activation of Sonic Hedgehog Leads to Survival Enhancement of Astrocytes via the GRP78-Dependent Pathway in Mice Infected with Angiostrongylus cantonensis |
| Q33685176 | Activation of Sonic hedgehog signaling in neural progenitor cells promotes glioma development in the zebrafish optic pathway |
| Q55048919 | Activity of Metabotropic Glutamate Receptor 4 Suppresses Proliferation and Promotes Apoptosis With Inhibition of Gli-1 in Human Glioblastoma Cells. |
| Q38204976 | Adult neurogenesis and glial oncogenesis: when the process fails. |
| Q47437183 | Association of chloride intracellular channel 4 and Indian hedgehog proteins with survival of patients with pancreatic ductal adenocarcinoma |
| Q37331760 | Beta-catenin-mediated Wnt signaling regulates neurogenesis in the ventral telencephalon |
| Q37604204 | Brain cancer stem cells. |
| Q33512545 | Brain tumor stem cells |
| Q36740051 | Brain tumour stem cells: the undercurrents of human brain cancer and their relationship to neural stem cells |
| Q39702845 | CD133+ cells from medulloblastoma and PNET cell lines are more resistant to cyclopamine inhibition of the sonic hedgehog signaling pathway than CD133- cells |
| Q39773200 | Cancer Stem Cells and Pediatric Solid Tumors |
| Q36636347 | Cathepsin B and uPAR regulate self-renewal of glioma-initiating cells through GLI-regulated Sox2 and Bmi1 expression |
| Q38673687 | Characterization of novel biomarkers in selecting for subtype specific medulloblastoma phenotypes. |
| Q36293538 | Ci antagonizes Hippo signaling in the somatic cells of the ovary to drive germline stem cell differentiation |
| Q41821677 | Cloning of zebrafish nkx6.2 and a comprehensive analysis of the conserved transcriptional response to Hedgehog/Gli signaling in the zebrafish neural tube |
| Q36280796 | Complex oncogenic signaling networks regulate brain tumor-initiating cells and their progenies: pivotal roles of wild-type EGFR, EGFRvIII mutant and hedgehog cascades and novel multitargeted therapies |
| Q34816792 | Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells |
| Q37677356 | Context-dependent regulation of the GLI code in cancer by HEDGEHOG and non-HEDGEHOG signals |
| Q27027214 | Context-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapy |
| Q38659223 | Control of Adult Neurogenesis by Short-Range Morphogenic-Signaling Molecules |
| Q38324359 | Cooperative requirement of the Gli proteins in neurogenesis |
| Q28588567 | Cortical thinning and hydrocephalus in mice lacking the immunoglobulin superfamily member CDO |
| Q39069500 | Curcumin suppresses malignant glioma cells growth and induces apoptosis by inhibition of SHH/GLI1 signaling pathway in vitro and vivo. |
| Q34580289 | Cyclopamine modulates γ-secretase-mediated cleavage of amyloid precursor protein by altering its subcellular trafficking and lysosomal degradation |
| Q28236409 | Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma |
| Q39964292 | Design, synthesis, and biological evaluation of estrone-derived hedgehog signaling inhibitors |
| Q39441380 | Developing Cures: Targeting Ontogenesis in Cancer. |
| Q40438917 | Differential modulation of Sonic-hedgehog-induced cerebellar granule cell precursor proliferation by the IGF signaling network |
| Q38804205 | Disruption of KIF3A in patient-derived glioblastoma cells: effects on ciliogenesis, hedgehog sensitivity, and tumorigenesis |
| Q46012040 | Distinct patterns of human medulloblastoma dissemination in the developing chick embryo nervous system. |
| Q41959796 | Divergent functions for eIF4E and S6 kinase by sonic hedgehog mitogenic signaling in the developing cerebellum |
| Q35095341 | Down-regulation of Gli transcription factor leads to the inhibition of migration and invasion of ovarian cancer cells via integrin β4-mediated FAK signaling |
| Q38999131 | Down-regulation of Gli-1 inhibits hepatocellular carcinoma cell migration and invasion |
| Q41492931 | E Proteins and Id2 converge on p57Kip2 to regulate cell cycle in neural cells. |
| Q33735966 | Early embryonic gene expression profiling of zebrafish prion protein (Prp2) morphants |
| Q33434938 | Efficient CPP-mediated Cre protein delivery to developing and adult CNS tissues |
| Q64230170 | Emerging Roles of Primary Cilia in Glioma |
| Q36145982 | Epithelial cells supply Sonic Hedgehog to the perinatal dentate gyrus via transport by platelets |
| Q30383486 | Eppur Si Muove: Evidence for an External Granular Layer and Possibly Transit Amplification in the Teleostean Cerebellum. |
| Q34127138 | Experimental approaches for the treatment of malignant gliomas |
| Q34346091 | Expression and prognostic significance of TCTN1 in human glioblastoma |
| Q36063470 | Expression of glioma-associated oncogene homolog 1 is associated with invasion and postoperative liver metastasis in colon cancer |
| Q37069074 | Expression of hedgehog pathway components in prostate carcinoma microenvironment: shifting the balance towards autocrine signalling |
| Q48115550 | Expression of stem cell markers in human astrocytomas of different WHO grades |
| Q33496580 | Expression of the glioma-associated oncogene homolog (GLI) 1 in human breast cancer is associated with unfavourable overall survival |
| Q92222198 | Extracellular Nanomatrix-Induced Self-Organization of Neural Stem Cells into Miniature Substantia Nigra-Like Structures with Therapeutic Effects on Parkinsonian Rats |
| Q37960622 | FOXA1: a transcription factor with parallel functions in development and cancer. |
| Q42113424 | FatJ acts via the Hippo mediator Yap1 to restrict the size of neural progenitor cell pools |
| Q35152994 | Fine-tuning of neurogenesis is essential for the evolutionary expansion of the cerebral cortex |
| Q91658846 | Functional role of WW domain-containing proteins in tumor biology and diseases: Insight into the role in ubiquitin-proteasome system |
| Q38213167 | G-protein-coupled receptors, Hedgehog signaling and primary cilia |
| Q34129830 | GANT-61 inhibits pancreatic cancer stem cell growth in vitro and in NOD/SCID/IL2R gamma null mice xenograft |
| Q37712773 | Genomic copy number imbalances associated with bone and non-bone metastasis of early-stage breast cancer |
| Q34615030 | Gli1 inhibition induces cell-cycle arrest and enhanced apoptosis in brain glioma cell lines |
| Q39589062 | Gli3 mediates cell survival and sensitivity to cyclopamine in pancreatic cancer |
| Q92893316 | Glial Factors Regulating White Matter Development and Pathologies of the Cerebellum |
| Q34735661 | Glial progenitors as targets for transformation in glioma |
| Q28079663 | Glioblastoma Stem-Like Cells: Characteristics, Microenvironment, and Therapy |
| Q35757997 | HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity |
| Q59792326 | Hedgehog Signaling in Cancer: A Prospective Therapeutic Target for Eradicating Cancer Stem Cells |
| Q37988650 | Hedgehog pathway and GLI1 isoforms in human cancer. |
| Q34075584 | Hedgehog signaling antagonist GDC-0449 (Vismodegib) inhibits pancreatic cancer stem cell characteristics: molecular mechanisms |
| Q37350250 | Hedgehog signaling in development and cancer. |
| Q27021460 | Hedgehog signaling pathway and its targets for treatment in basal cell carcinoma |
| Q28544108 | Hedgehog signaling pathway is active in GBM with GLI1 mRNA expression showing a single continuous distribution rather than discrete high/low clusters |
| Q35570435 | Hedgehog signaling promotes medulloblastoma survival via Bc/II |
| Q37345013 | Hedgehog-Gli signaling pathway inhibitors as anticancer agents. |
| Q24563861 | Hedgehog-interacting protein is highly expressed in endothelial cells but down-regulated during angiogenesis and in several human tumors |
| Q37259925 | Hedgehog-producing cancer cells respond to and require autocrine Hedgehog activity |
| Q51381877 | Hedgehog/Gli1 signal pathway facilitates proliferation, invasion, and migration of cutaneous SCC through regulating VEGF. |
| Q37492187 | High-throughput microRNA profiling of pediatric high-grade gliomas. |
| Q36042084 | Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion |
| Q61446577 | Identification of CD24 as a marker of Patched1 deleted medulloblastoma-initiating neural progenitor cells |
| Q39997955 | Identification, functional characterization, and pathobiological significance of GLI1 isoforms in human cancers |
| Q38561982 | Identifying hedgehog signaling specific microRNAs in glioblastomas |
| Q33735813 | In the absence of Sonic hedgehog, p53 induces apoptosis and inhibits retinal cell proliferation, cell-cycle exit and differentiation in zebrafish |
| Q33718581 | Inactivation of the transcription factor GLI1 accelerates pancreatic cancer progression. |
| Q30414501 | Inflammation and Gliomagenesis: Bi-Directional Communication at Early and Late Stages of Tumor Progression |
| Q34500647 | Inhibition of Sonic hedgehog and Notch pathways enhances sensitivity of CD133(+) glioma stem cells to temozolomide therapy |
| Q37487211 | Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling |
| Q36706719 | Insight in glioma susceptibility through an analysis of 6p22.3, 12p13.33-12.1, 17q22-23.2 and 18q23 SNP genotypes in familial and non-familial glioma |
| Q49957684 | Interaction between STAT3 and GLI1/tGLI1 oncogenic transcription factors promotes the aggressiveness of triple-negative breast cancers and HER2-enriched breast cancer |
| Q35048554 | Investigations on inhibitors of hedgehog signal pathway: a quantitative structure-activity relationship study |
| Q35146261 | Isolation of distinct cell populations from the developing cerebellum by microdissection |
| Q36895367 | Kif3a is necessary for initiation and maintenance of medulloblastoma |
| Q36529262 | LSD1 co-repressor Rcor2 orchestrates neurogenesis in the developing mouse brain |
| Q41238772 | Loss of Suppressor of Fused in Mid-Corticogenesis Leads to the Expansion of Intermediate Progenitors |
| Q28593489 | Loss of the serine/threonine kinase fused results in postnatal growth defects and lethality due to progressive hydrocephalus |
| Q37089385 | Loss-of-function mutations in the human GLI2 gene are associated with pituitary anomalies and holoprosencephaly-like features |
| Q37186416 | Medulloblastoma stem cells |
| Q35722779 | Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways. |
| Q26770788 | Molecular Pathways Underlying Projection Neuron Production and Migration during Cerebral Cortical Development |
| Q26751190 | Morphogenetic and Histogenetic Roles of the Temporal-Spatial Organization of Cell Proliferation in the Vertebrate Corticogenesis as Revealed by Inter-specific Analyses of the Optic Tectum Cortex Development |
| Q50421452 | Multiple roles of Sonic Hedgehog in the developing human cortex are suggested by its widespread distribution. |
| Q34085883 | NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53. |
| Q90679948 | Negative Regulation of mTOR Signaling Restricts Cell Proliferation in the Floor Plate |
| Q37369781 | Negative regulation of Hedgehog signaling by liver X receptors |
| Q38815922 | Neural stem cells, the subventricular zone and radiotherapy: implications for treating glioblastoma |
| Q34424298 | Neural transcription factors: from embryos to neural stem cells |
| Q37775962 | Novel investigational drugs for basal cell carcinoma |
| Q41151636 | Nucleolar and spindle associated protein 1 promotes the aggressiveness of astrocytoma by activating the Hedgehog signaling pathway |
| Q35748808 | Null mutation of DNA strand break-binding molecule poly(ADP-ribose) polymerase causes medulloblastomas in p53(-/-) mice |
| Q38833100 | OTX2 exhibits cell-context-dependent effects on cellular and molecular properties of human embryonic neural precursors and medulloblastoma cells |
| Q37230949 | Origins and clinical implications of the brain tumor stem cell hypothesis |
| Q28646188 | Osteogenesis and neurogenesis: a robust link also for language evolution |
| Q38742740 | Overexpression of SCUBE2 Inhibits Proliferation, Migration, and Invasion in Glioma Cells |
| Q28300184 | Paradoxical dysregulation of the neural stem cell pathway sonic hedgehog-Gli1 in autoimmune encephalomyelitis and multiple sclerosis |
| Q21284139 | Perlecan controls neurogenesis in the developing telencephalon |
| Q34499215 | Perlecan, a candidate gene for the CAPB locus, regulates prostate cancer cell growth via the Sonic Hedgehog pathway |
| Q44723208 | Persistent progenitors at the retinal margin of ptc+/- mice. |
| Q36509989 | Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development |
| Q37264332 | Progress on potential strategies to target brain tumor stem cells. |
| Q34775969 | Proliferation of murine midbrain neural stem cells depends upon an endogenous sonic hedgehog (Shh) source |
| Q64085816 | Promyelocytic leukemia zinc finger is involved in the formation of deep layer cortical neurons |
| Q36891365 | Prostate cancer and Hedgehog signalling pathway. |
| Q38978119 | Pyrvinium attenuates Hedgehog signaling downstream of smoothened. |
| Q36987393 | REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma |
| Q54384404 | Role of sonic hedgehog signaling in migration of cell lines established from CD133-positive malignant glioma cells. |
| Q38409513 | Selective modulation of Hedgehog/GLI target gene expression by epidermal growth factor signaling in human keratinocytes. |
| Q34938518 | Selective translocation of intracellular Smoothened to the primary cilium in response to Hedgehog pathway modulation |
| Q28248315 | Shh and Gli3 regulate formation of the telencephalic-diencephalic junction and suppress an isthmus-like signaling source in the forebrain |
| Q38964051 | Sialidase NEU4 is involved in glioblastoma stem cell survival. |
| Q58790346 | Sonic Hedgehog Signaling Rises to the Surface: Emerging Roles in Neocortical Development |
| Q44637005 | Sonic Hedgehog and Bone Morphogenetic Protein Regulate Interneuron Development from Dorsal Telencephalic ProgenitorsIn Vitro |
| Q42967518 | Sonic Hedgehog modulates EGFR dependent proliferation of neural stem cells during late mouse embryogenesis through EGFR transactivation |
| Q34432502 | Sonic hedgehog (Shh)/Gli modulates the spatial organization of neuroepithelial cell proliferation in the developing chick optic tectum |
| Q33838320 | Sonic hedgehog and notch signaling can cooperate to regulate neurogenic divisions of neocortical progenitors |
| Q47182298 | Sonic hedgehog antagonists reduce size and alter patterning of the frog inner ear. |
| Q42699442 | Sonic hedgehog controls stem cell behavior in the postnatal and adult brain |
| Q34997644 | Sonic hedgehog elevates N-myc gene expression in neural stem cells |
| Q37356915 | Sonic hedgehog in gastric physiology and neoplastic transformation: friend or foe? |
| Q30573858 | Sonic hedgehog signaling regulates mode of cell division of early cerebral cortex progenitors and increases astrogliogenesis. |
| Q38366625 | Stereoselective synthesis of F-ring saturated estrone-derived inhibitors of Hedgehog signaling based on cyclopamine |
| Q41676958 | Stimulation of IL-1β and IL-6 through NF-κB and sonic hedgehog-dependent pathways in mouse astrocytes by excretory/secretory products of fifth-stage larval Angiostrongylus cantonensis |
| Q38602380 | Studies directed toward the elucidation of the pharmacophore of steroid-based Sonic Hedgehog signaling inhibitors |
| Q36739421 | Suppressors of hedgehog signaling: Linking aberrant development of neural progenitors and tumorigenesis. |
| Q92965728 | TGLI1 transcription factor mediates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment |
| Q35076275 | Targeting the Hedgehog pathway in cancer |
| Q88608509 | The Dorsal Wave of Neocortical Oligodendrogenesis Begins Embryonically and Requires Multiple Sources of Sonic Hedgehog |
| Q39825301 | The G protein-coupled receptor 87 is necessary for p53-dependent cell survival in response to genotoxic stress |
| Q37417201 | The GLI1 splice variant TGLI1 promotes glioblastoma angiogenesis and growth |
| Q34685494 | The Gli code: an information nexus regulating cell fate, stemness and cancer. |
| Q41694131 | The Hedgehog-GLI pathway in embryonic development and cancer: implications for pulmonary oncology therapy. |
| Q37814123 | The Human Glioma-Associated Oncogene Homolog 1 (GLI1) Family of Transcription Factors in Gene Regulation and Diseases |
| Q36368743 | The Role of Sonic Hedgehog in the Specification of Human Cortical Progenitors In Vitro. |
| Q99726455 | The effects of hedgehog ligand neutralising antibody 5E1 in a mouse model of endometriosis |
| Q37551261 | The emerging role of insulin and insulin-like growth factor signaling in cancer stem cells |
| Q33855554 | The p53 inhibitor MDM2 facilitates Sonic Hedgehog-mediated tumorigenesis and influences cerebellar foliation |
| Q37780433 | The perivascular niche microenvironment in brain tumor progression |
| Q46108387 | The role of Sonic hedgehog of neural origin in thalamic differentiation in the mouse. |
| Q24794932 | The therapeutic potential of modulators of the Hedgehog-Gli signaling pathway |
| Q38031211 | The utility of hedgehog signaling pathway inhibition for cancer |
| Q24814971 | The zebrafish mutants dre, uki, and lep encode negative regulators of the hedgehog signaling pathway |
| Q34064658 | Toll-like receptor 3 regulates neural stem cell proliferation by modulating the Sonic Hedgehog pathway |
| Q37522979 | Transcription factors and neural stem cell self-renewal, growth and differentiation |
| Q42009682 | Transforming Growth Factor-α Improves Memory Impairment and Neurogenesis Following Ischemia Reperfusion |
| Q37129807 | Treatment resistance mechanisms of malignant glioma tumor stem cells |
| Q37285008 | Turning cancer stem cells inside out: an exploration of glioma stem cell signaling pathways |
| Q35219125 | Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells. |
| Q36127410 | VHL regulates the effects of miR-23b on glioma survival and invasion via suppression of HIF-1α/VEGF and β-catenin/Tcf-4 signaling |
| Q38660744 | WNT signaling in glioblastoma and therapeutic opportunities |
| Q24307092 | Wnt regulation of progenitor maturation in the cortex depends on Shh or fibroblast growth factor 2 |
| Q28585721 | alphaE-catenin controls cerebral cortical size by regulating the hedgehog signaling pathway |
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