| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2001PNAS...98.3673S |
| P356 | DOI | 10.1073/PNAS.051454398 |
| P932 | PMC publication ID | 31110 |
| P698 | PubMed publication ID | 11259642 |
| P5875 | ResearchGate publication ID | 12072407 |
| P2093 | author name string | S. Sherman | |
| L. Kirnarsky | |||
| Q. A. Sun | |||
| V. N. Gladyshev | |||
| P2860 | cites work | Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases | Q22003810 |
| Human mitochondrial thioredoxin reductase cDNA cloning, expression and genomic organization | Q22009451 | ||
| Identification of a new type of mammalian peroxiredoxin that forms an intramolecular disulfide as a reaction intermediate | Q22253468 | ||
| Thioredoxin reductase | Q24531944 | ||
| The mechanism of thioredoxin reductase from human placenta is similar to the mechanisms of lipoamide dehydrogenase and glutathione reductase and is distinct from the mechanism of thioredoxin reductase from Escherichia coli | Q24670171 | ||
| Structure and mechanism of mammalian thioredoxin reductase: the active site is a redox-active selenolthiol/selenenylsulfide formed from the conserved cysteine-selenocysteine sequence | Q24683648 | ||
| Convergent evolution of similar function in two structurally divergent enzymes | Q27663753 | ||
| Grx5 glutaredoxin plays a central role in protection against protein oxidative damage in Saccharomyces cerevisiae | Q27933647 | ||
| Identification and functional characterization of a novel mitochondrial thioredoxin system in Saccharomyces cerevisiae. | Q27937893 | ||
| Cloning, sequencing and functional expression of a novel human thioredoxin reductase | Q28115611 | ||
| Structural organization of the human glutathione reductase gene: determination of correct cDNA sequence and identification of a mitochondrial leader sequence | Q28138037 | ||
| Assay of glutathione reductase in crude tissue homogenates using 5,5'-dithiobis(2-nitrobenzoic acid) | Q28293760 | ||
| Structure of the detoxification catalyst mercuric ion reductase from Bacillus sp. strain RC607 | Q28328504 | ||
| Contrasting patterns of regulation of the antioxidant selenoproteins, thioredoxin reductase, and glutathione peroxidase, in cancer cells | Q28509640 | ||
| Molecular cloning and characterization of a mitochondrial selenocysteine-containing thioredoxin reductase from rat liver | Q28578397 | ||
| Essential role of selenium in the catalytic activities of mammalian thioredoxin reductase revealed by characterization of recombinant enzymes with selenocysteine mutations | Q28581387 | ||
| Tissue-specific functions of individual glutathione peroxidases | Q28645787 | ||
| Selenocysteine | Q29409802 | ||
| Selenocysteine, identified as the penultimate C-terminal residue in human T-cell thioredoxin reductase, corresponds to TGA in the human placental gene | Q29409898 | ||
| Redox signaling: hydrogen peroxide as intracellular messenger | Q33689299 | ||
| Antioxidant defence mechanisms: from the beginning to the end (of the beginning). | Q33750081 | ||
| Glutathione and its role in cellular functions | Q33777917 | ||
| Alternative routes for entry of HgX2 into the active site of mercuric ion reductase depend on the nature of the X ligands | Q33856051 | ||
| Redox-dependent signal transduction | Q33957112 | ||
| Glutaredoxin. | Q34288574 | ||
| Mechanism and structure of thioredoxin reductase from Escherichia coli | Q34295184 | ||
| Purification and characterization of glutathione reductase from Rhodospirillum rubrum | Q34549165 | ||
| Mammalian thioredoxin reductase: oxidation of the C-terminal cysteine/selenocysteine active site forms a thioselenide, and replacement of selenium with sulfur markedly reduces catalytic activity | Q35076291 | ||
| Molecular modeling and in vitro activity of an HIV-1-encoded glutathione peroxidase | Q35771030 | ||
| 7 Plotting methods for analyzing enzyme rate data | Q36541247 | ||
| Regulation of human thioredoxin reductase expression and activity by 3'-untranslated region selenocysteine insertion sequence and mRNA instability elements | Q40932866 | ||
| A hypothesis on the catalytic mechanism of the selenoenzyme thioredoxin reductase | Q42990843 | ||
| Mitochondrial thioredoxin reductase in bovine adrenal cortex its purification, properties, nucleotide/amino acid sequences, and identification of selenocysteine | Q47937944 | ||
| Unique gene organization of thioredoxin and thioredoxin reductase in Mycobacterium leprae. | Q48073526 | ||
| Ultrastructural demonstration of thioredoxin and thioredoxin reductase in rat hepatocytes | Q67953078 | ||
| Thioltransferase in human red blood cells: kinetics and equilibrium | Q67968629 | ||
| Preparation of membrane fractions | Q68730147 | ||
| Glutathione reductase | Q70123854 | ||
| Use of protein A-bearing staphylococci for the immunoprecipitation and isolation of antigens from cells | Q70191384 | ||
| Glutaredoxin from calf thymus. Purification to homogeneity | Q70239784 | ||
| 36 Thioltransferase | Q71070205 | ||
| Thioredoxin reductase from Plasmodium falciparum: evidence for interaction between the C-terminal cysteine residues and the active site disulfide-dithiol | Q74599269 | ||
| Thioredoxin reductase-thioredoxin fusion enzyme from Mycobacterium leprae: comparison with the separately expressed thioredoxin reductase | Q77569638 | ||
| Probing cellular protein targets of H2O2 with fluorescein-conjugated iodoacetamide and antibodies to fluorescein | Q77715240 | ||
| Preparation and assay of mammalian thioredoxin and thioredoxin reductase | Q77907868 | ||
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | glutathione | Q116907 |
| Thioredoxin reductase 3 | Q21992227 | ||
| Thioredoxin reductase 1 | Q21992230 | ||
| P304 | page(s) | 3673–3678 | |
| P577 | publication date | 2001-03-27 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Selenoprotein oxidoreductase with specificity for thioredoxin and glutathione systems | |
| P478 | volume | 98 |
| Q51578601 | A small molecule probe reveals declined mitochondrial thioredoxin reductase activity in a Parkinson's disease model. |
| Q44572770 | Absolute gene expression patterns of thioredoxin and glutaredoxin redox systems in mouse |
| Q44285322 | Alternative mRNAs arising from trans-splicing code for mitochondrial and cytosolic variants of Echinococcus granulosus thioredoxin Glutathione reductase |
| Q24297014 | An alternative splicing variant of the selenoprotein thioredoxin reductase is a modulator of estrogen signaling |
| Q36729542 | Auranofin is a potent suppressor of osteosarcoma metastasis. |
| Q33717530 | CUG start codon generates thioredoxin/glutathione reductase isoforms in mouse testes |
| Q33326607 | Cell death by SecTRAPs: thioredoxin reductase as a prooxidant killer of cells |
| Q37217435 | Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity. |
| Q34931064 | Characterization of protein targets of mammalian thioredoxin reductases |
| Q28083118 | Cross Talk between Two Antioxidant Systems, Thioredoxin and DJ-1: Consequences for Cancer |
| Q34084972 | Crystal structures of oxidized and reduced mitochondrial thioredoxin reductase provide molecular details of the reaction mechanism |
| Q28510029 | Cytoplasmic thioredoxin reductase is essential for embryogenesis but dispensable for cardiac development |
| Q41281464 | Differential expression of disulfide reductase enzymes in a free-living platyhelminth (Dugesia dorotocephala). |
| Q28588321 | Effects of thioredoxin reductase-1 deletion on embryogenesis and transcriptome |
| Q24563493 | Essential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart function |
| Q35813283 | Flavoprotein disulfide reductases: advances in chemistry and function |
| Q28396740 | Gene expression changes for antioxidants pathways in the mouse cochlea: relations to age-related hearing deficits |
| Q24795742 | Genomic organisation and alternative splicing of mouse and human thioredoxin reductase 1 genes |
| Q28576854 | Glutaredoxins catalyze the reduction of glutathione by dihydrolipoamide with high efficiency |
| Q34335643 | Gram-positive pathogenic bacteria induce a common early response in human monocytes |
| Q24537426 | How selenium has altered our understanding of the genetic code |
| Q37205903 | Identification of Michael acceptor-centric pharmacophores with substituents that yield strong thioredoxin reductase inhibitory character correlated to antiproliferative activity |
| Q43078941 | In vitro killing action of auranofin on Taenia crassiceps metacestode (cysticerci) and inactivation of thioredoxin-glutathione reductase (TGR). |
| Q40043936 | Induction of cell membrane protrusions by the N-terminal glutaredoxin domain of a rare splice variant of human thioredoxin reductase 1. |
| Q24652462 | Inhibition of Schistosoma mansoni thioredoxin-glutathione reductase by auranofin: structural and kinetic aspects |
| Q46919473 | Inhibitory effects and analysis of RNA interference on thioredoxin glutathione reductase expression in Schistosoma japonicum |
| Q58762686 | Insight into the Mechanistic Basis of the Hysteretic-Like Kinetic Behavior of Thioredoxin-Glutathione Reductase (TGR) |
| Q36856181 | Investigations of the catalytic mechanism of thioredoxin glutathione reductase from Schistosoma mansoni |
| Q47313010 | Kinetic characterization of wild-type and mutant human thioredoxin glutathione reductase defines its reaction and regulatory mechanisms |
| Q47068703 | Lifespan decrease in a Caenorhabditis elegans mutant lacking TRX-1, a thioredoxin expressed in ASJ sensory neurons |
| Q34568264 | Linked thioredoxin-glutathione systems in platyhelminth parasites: alternative pathways for glutathione reduction and deglutathionylation. |
| Q46497068 | Mammalian selenoprotein thioredoxin-glutathione reductase. Roles in disulfide bond formation and sperm maturation |
| Q28570245 | Mammalian thioredoxin reductase 1: roles in redox homoeostasis and characterization of cellular targets |
| Q27663601 | Mapping the Catalytic Cycle of Schistosoma mansoni Thioredoxin Glutathione Reductase by X-ray Crystallography |
| Q33741131 | Mechanistic and kinetic details of catalysis of thiol-disulfide exchange by glutaredoxins and potential mechanisms of regulation |
| Q43848623 | Methylseleninate is a substrate rather than an inhibitor of mammalian thioredoxin reductase. Implications for the antitumor effects of selenium |
| Q34077498 | Mitochondrial Thioredoxin-Glutathione Reductase from LarvalTaenia crassiceps(Cysticerci) |
| Q34300952 | Mouse Models of Oxidative Stress Indicate a Role for Modulating Healthy Aging |
| Q24805819 | Nematode selenoproteome: the use of the selenocysteine insertion system to decode one codon in an animal genome? |
| Q39458558 | New Challenges to Study Heterogeneity in Cancer Redox Metabolism |
| Q42050290 | Non-animal origin of animal thioredoxin reductases: implications for selenocysteine evolution and evolution of protein function through carboxy-terminal extensions |
| Q38651048 | Nuclear selenoproteins and genome maintenance |
| Q40506655 | Overexpression of enzymatically active human cytosolic and mitochondrial thioredoxin reductase in HEK-293 cells. Effect on cell growth and differentiation. |
| Q44635825 | Overexpression of thioredoxin reductase 1 regulates NF‐κB activation |
| Q44922003 | Oxidation of thioredoxin reductase in HeLa cells stimulated with tumor necrosis factor-alpha. |
| Q55043886 | Oxidative stress and redox regulation of gametogenesis, fertilization, and embryonic development. |
| Q39280599 | Oxidative stress in malaria and artemisinin combination therapy: Pros and Cons |
| Q28392715 | Paradoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health Implications |
| Q89135839 | Peroxiredoxin 6 is the primary antioxidant enzyme for the maintenance of viability and DNA integrity in human spermatozoa |
| Q30042295 | Plasmodium falciparum possesses a classical glutaredoxin and a second, glutaredoxin-like protein with a PICOT homology domain |
| Q39599862 | Platyhelminth mitochondrial and cytosolic redox homeostasis is controlled by a single thioredoxin glutathione reductase and dependent on selenium and glutathione. |
| Q28571098 | Rapid induction of cell death by selenium-compromised thioredoxin reductase 1 but not by the fully active enzyme containing selenocysteine |
| Q29619367 | Reactive oxygen species, antioxidants, and the mammalian thioredoxin system |
| Q37062221 | Redox Pioneer: Professor Vadim N. Gladyshev |
| Q33649846 | Redox regulation of cell survival by the thioredoxin superfamily: an implication of redox gene therapy in the heart |
| Q36693385 | Redox regulation of cellular stress response in aging and neurodegenerative disorders: role of vitagenes. |
| Q34139200 | Regulation of selenocysteine incorporation into the selenium transport protein, selenoprotein P. |
| Q35540175 | Roles of antioxidants on prolonged storage of avian spermatozoa in vivo and in vitro |
| Q38052148 | Roles of reactive oxygen species in the fate of stem cells. |
| Q28084516 | Selenium and its supplementation in cardiovascular disease--what do we know? |
| Q37290639 | Selenium and thyroid autoimmunity. |
| Q55082777 | Selenium-Dependent Antioxidant Enzymes: Actions and Properties of Selenoproteins. |
| Q35119560 | Selenium. Role of the essential metalloid in health |
| Q28085052 | Selenocysteine incorporation: A trump card in the game of mRNA decay |
| Q50192080 | Selenoproteins and cardiovascular stress |
| Q33913069 | Selenoproteins: molecular pathways and physiological roles. |
| Q24295125 | Spermatocyte/spermatid-specific thioredoxin-3, a novel Golgi apparatus-associated thioredoxin, is a specific marker of aberrant spermatogenesis |
| Q34104400 | Sptrx-2, a fusion protein composed of one thioredoxin and three tandemly repeated NDP-kinase domains is expressed in human testis germ cells |
| Q27675837 | Structural Analysis of Glutaredoxin Domain of Mus musculus Thioredoxin Glutathione Reductase |
| Q36840522 | Targeted disruption of glutathione peroxidase 4 in mouse skin epithelial cells impairs postnatal hair follicle morphogenesis that is partially rescued through inhibition of COX-2. |
| Q33291299 | Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide |
| Q38956970 | The Architecture of Thiol Antioxidant Systems among Invertebrate Parasites. |
| Q40229976 | The Enzymatic and Structural Basis for Inhibition of Echinococcus granulosus Thioredoxin Glutathione Reductase by Gold(I). |
| Q38868418 | The disulfide redox system of Schistosoma mansoni and the importance of a multifunctional enzyme, thioredoxin glutathione reductase |
| Q30716821 | The diversity and evolution of thioredoxin reductase: new perspectives |
| Q33595879 | The effects of dietary restriction on oxidative stress in rodents |
| Q38828101 | The expression and activity of thioredoxin reductase 1 splice variants v1 and v2 regulate the expression of genes associated with differentiation and adhesion |
| Q23910066 | The mammalian testis-specific thioredoxin system |
| Q44484536 | The mechanism of high Mr thioredoxin reductase from Drosophila melanogaster |
| Q36742084 | The rare TXNRD1_v3 ("v3") splice variant of human thioredoxin reductase 1 protein is targeted to membrane rafts by N-acylation and induces filopodia independently of its redox active site integrity. |
| Q26829701 | The redox biology of schistosome parasites and applications for drug development |
| Q38547857 | The role of cellular oxidoreductases in viral entry and virus infection-associated oxidative stress: potential therapeutic applications |
| Q51463230 | The role of electrostatics in TrxR electron transfer mechanism: A computational approach. |
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