| scholarly article | Q13442814 |
| P50 | author | Ernst R Werner | Q41776119 |
| Antonius Cornelis Franciscus Gorren | Q67504072 | ||
| P2093 | author name string | K Schmidt | |
| B Mayer | |||
| W C Sessa | |||
| W R Kukovetz | |||
| C Völker | |||
| B Klösch | |||
| B M List | |||
| P2860 | cites work | Cysteine 99 of endothelial nitric oxide synthase (NOS-III) is critical for tetrahydrobiopterin-dependent NOS-III stability and activity | Q24303789 |
| Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 | Q25938983 | ||
| A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding | Q25938984 | ||
| Molecular cloning and characterization of human endothelial nitric oxide synthase | Q28187817 | ||
| Identification of covalently bound amino-terminal myristic acid in endothelial nitric oxide synthase | Q28285966 | ||
| Targeting of nitric oxide synthase to endothelial cell caveolae via palmitoylation: implications for nitric oxide signaling | Q28609890 | ||
| Determination of nitric oxide synthase cofactors: heme, FAD, FMN, and tetrahydrobiopterin | Q28609891 | ||
| Molecular cloning and expression of a cDNA encoding endothelial cell nitric oxide synthase | Q30311435 | ||
| Characterization of heme-deficient neuronal nitric-oxide synthase reveals a role for heme in subunit dimerization and binding of the amino acid substrate and tetrahydrobiopterin. | Q30423824 | ||
| Agonist-modulated palmitoylation of endothelial nitric oxide synthase | Q71670880 | ||
| The Golgi association of endothelial nitric oxide synthase is necessary for the efficient synthesis of nitric oxide | Q71703916 | ||
| Native low-density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anion | Q71705751 | ||
| Biosynthesis and palmitoylation of endothelial nitric oxide synthase: mutagenesis of palmitoylation sites, cysteines-15 and/or -26, argues against depalmitoylation-induced translocation of the enzyme | Q71715383 | ||
| Macrophage nitric oxide synthase subunits. Purification, characterization, and role of prosthetic groups and substrate in regulating their association into a dimeric enzyme | Q72097975 | ||
| Mutation of N-myristoylation site converts endothelial cell nitric oxide synthase from a membrane to a cytosolic protein | Q30464616 | ||
| Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoform | Q30990194 | ||
| Molecular cloning and characterization of the constitutive bovine aortic endothelial cell nitric oxide synthase | Q31172360 | ||
| Expression of human inducible nitric oxide synthase in a tetrahydrobiopterin (H4B)-deficient cell line: H4B promotes assembly of enzyme subunits into an active dimer | Q33722120 | ||
| Characterization of a catalytically self-sufficient 119,000-dalton cytochrome P-450 monooxygenase induced by barbiturates in Bacillus megaterium. | Q34165537 | ||
| Nitric oxide synthases reveal a role for calmodulin in controlling electron transfer | Q36672374 | ||
| Heme requirement for production of active endothelial nitric oxide synthase in baculovirus-infected insect cells. | Q36677815 | ||
| Nitric oxide synthase is localized predominantly in the Golgi apparatus and cytoplasmic vesicles of vascular endothelial cells | Q36680797 | ||
| Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-L-arginine | Q36817052 | ||
| Purification of a soluble isoform of guanylyl cyclase-activating-factor synthase | Q37368113 | ||
| Purification and characterization of the cytokine-induced macrophage nitric oxide synthase: an FAD- and FMN-containing flavoprotein | Q37587741 | ||
| Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells | Q37628594 | ||
| Characterization of bovine endothelial nitric oxide synthase expressed in E. coli. | Q38361671 | ||
| Nitric oxide synthases: why so complex? | Q40393867 | ||
| Nitric oxide synthases: properties and catalytic mechanism | Q40401516 | ||
| In search of a function for tetrahydrobiopterin in the biosynthesis of nitric oxide. | Q40403340 | ||
| Structural analysis of porcine brain nitric oxide synthase reveals a role for tetrahydrobiopterin and L-arginine in the formation of an SDS-resistant dimer. | Q40788969 | ||
| Acylation targets emdothelial nitric-oxide synthase to plasmalemmal caveolae | Q41215934 | ||
| Intracellular assembly of inducible NO synthase is limited by nitric oxide-mediated changes in heme insertion and availability | Q41217633 | ||
| Large-scale purification of rat brain nitric oxide synthase from baculovirus overexpression system | Q41249824 | ||
| Oligomerization of endothelial nitric oxide synthase. Evidence for a dominant negative effect of truncation mutants | Q41270371 | ||
| Role of the enzyme calmodulin-binding domain in membrane association and phospholipid inhibition of endothelial nitric oxide synthase | Q41334662 | ||
| Endothelial nitric oxide synthase. N-terminal myristoylation determines subcellular localization | Q41559089 | ||
| Generation of superoxide by purified brain nitric oxide synthase | Q41590269 | ||
| Nitric oxide synthase-catalyzed activation of oxygen and reduction of cytochromes: reaction mechanisms and possible physiological implications | Q41764124 | ||
| Expression of rat brain nitric oxide synthase in baculovirus-infected insect cells and characterization of the purified enzyme | Q41840509 | ||
| Synthesis and characterization of 3H-labelled tetrahydrobiopterin | Q41998595 | ||
| Overexpression of neuronal nitric oxide synthase in insect cells reveals requirement of haem for tetrahydrobiopterin binding | Q42064550 | ||
| Recombinant endothelial nitric oxide synthase: post-translational modifications in a baculovirus expression system. | Q42066657 | ||
| Radioligand binding to muscarinic receptors of bovine aortic endothelial cells | Q42560536 | ||
| Ca2+/calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase | Q42706218 | ||
| Endothelial nitric-oxide synthase. Expression in Escherichia coli, spectroscopic characterization, and role of tetrahydrobiopterin in dimer formation. | Q46275700 | ||
| The pteridine binding site of brain nitric oxide synthase. Tetrahydrobiopterin binding kinetics, specificity, and allosteric interaction with the substrate domain | Q48123444 | ||
| Glutamate receptors induce a burst of superoxide via activation of nitric oxide synthase in arginine-depleted neurons | Q48137669 | ||
| Multiple catalytic functions of brain nitric oxide synthase. Biochemical characterization, cofactor-requirement, and the role of N omega-hydroxy-L-arginine as an intermediate | Q48249201 | ||
| Ca2+/calmodulin-dependent cytochrome c reductase activity of brain nitric oxide synthase | Q48470102 | ||
| Brain nitric oxide synthase is a biopterin- and flavin-containing multi-functional oxido-reductase. | Q48671468 | ||
| Kinetics and Mechanism of Tetrahydrobiopterin-induced Oxidation of Nitric Oxide | Q61906322 | ||
| Molecular mechanisms of inhibition of porcine brain nitric oxide synthase by the antinociceptive drug 7-nitro-indazole | Q61906325 | ||
| NG-methyl-L-arginine functions as an alternate substrate and mechanism-based inhibitor of nitric oxide synthase. | Q64921353 | ||
| An improved staining procedure for the detection of the peroxidase activity of cytochrome P-450 on sodium dodecyl sulfate polyacrylamide gels | Q67526123 | ||
| Effects of Cerebral Ischemia in Mice Deficient in Neuronal Nitric Oxide Synthase | Q71647466 | ||
| The inhibition of the constitutive bovine endothelial nitric oxide synthase by imidazole and indazole agents | Q71659624 | ||
| Tetrahydrobiopterin and dysfunction of endothelial nitric oxide synthase in coronary arteries | Q71665246 | ||
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | endothelium | Q111140 |
| sapropterin | Q419808 | ||
| P304 | page(s) | 159-165 | |
| P577 | publication date | 1997-04-01 | |
| P1433 | published in | Biochemical Journal | Q864221 |
| P1476 | title | Characterization of bovine endothelial nitric oxide synthase as a homodimer with down-regulated uncoupled NADPH oxidase activity: tetrahydrobiopterin binding kinetics and role of haem in dimerization | |
| P478 | volume | 323 ( Pt 1) |
| Q27621434 | Allosteric inhibitors of inducible nitric oxide synthase dimerization discovered via combinatorial chemistry |
| Q42988594 | Allosteric modulation of rat brain nitric oxide synthase by the pterin-site enzyme inhibitor 4-aminotetrahydrobiopterin |
| Q41684081 | Biosynthesis and action of nitric oxide in mammalian cells |
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| Q38991320 | Cell type-specific recycling of tetrahydrobiopterin by dihydrofolate reductase explains differential effects of 7,8-dihydrobiopterin on endothelial nitric oxide synthase uncoupling |
| Q38586940 | Clinical Significance of Endothelial Dysfunction in Essential Hypertension. |
| Q42238880 | Combined oral administration of L-arginine and tetrahydrobiopterin in a rat model of pulmonary arterial hypertension. |
| Q27683748 | Communication between the Zinc and Tetrahydrobiopterin Binding Sites in Nitric Oxide Synthase |
| Q28574134 | Contrasting effects of N5-substituted tetrahydrobiopterin derivatives on phenylalanine hydroxylase, dihydropteridine reductase and nitric oxide synthase |
| Q36021044 | DNA strand breaks induced by nuclear hijacking of neuronal NOS as an anti-cancer effect of 2-methoxyestradiol |
| Q42990485 | Effects of pH on the structure and function of neuronal nitric oxide synthase |
| Q98774303 | Endothelial Dysfunction in COVID-19: Lessons Learned from Coronaviruses |
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| Q35110921 | Genetic influence on cigarette-induced cardiovascular disease |
| Q73666038 | Genotype dependent and cigarette specific effects on endothelial nitric oxide synthase gene expression and enzyme activity |
| Q24293579 | Human endothelial dihydrofolate reductase low activity limits vascular tetrahydrobiopterin recycling |
| Q33739113 | Hypoxia and reoxygenation induce endothelial nitric oxide synthase uncoupling in endothelial cells through tetrahydrobiopterin depletion and S-glutathionylation |
| Q37683440 | Induction of microRNA-138 by pro-inflammatory cytokines causes endothelial cell dysfunction |
| Q37621624 | Interaction between neuronal nitric-oxide synthase and tetrahydrobiopterin revisited: studies on the nature and mechanism of tight pterin binding. |
| Q33631306 | Mammalian nitric oxide synthases |
| Q36002621 | Myocardial ischemia results in tetrahydrobiopterin (BH4) oxidation with impaired endothelial function ameliorated by BH4. |
| Q28247092 | Nitric oxide synthases: regulation and function |
| Q28207668 | Nitric oxide synthases: structure, function and inhibition |
| Q42996395 | Nitric oxide-induced autoinhibition of neuronal nitric oxide synthase in the presence of the autoxidation-resistant pteridine 5-methyltetrahydrobiopterin |
| Q37887771 | Nitric oxide: a guardian for vascular grafts? |
| Q33775518 | Peroxynitrite induces destruction of the tetrahydrobiopterin and heme in endothelial nitric oxide synthase: transition from reversible to irreversible enzyme inhibition |
| Q33793673 | Pharmacological modulation of nitric oxide synthesis by mechanism-based inactivators and related inhibitors |
| Q35874976 | Reactive oxygen species in vascular biology: implications in hypertension |
| Q30406156 | Regulation of cellular communication by signaling microdomains in the blood vessel wall |
| Q33926497 | Role of a Conserved Tyrosine Residue in the FMN-Heme Interdomain Electron Transfer in Inducible Nitric Oxide Synthase. |
| Q42718346 | S-glutathionylation reshapes our understanding of endothelial nitric oxide synthase uncoupling and nitric oxide/reactive oxygen species-mediated signaling |
| Q36139878 | Selective Irreversible Inhibition of Neuronal and Inducible Nitric-oxide Synthase in the Combined Presence of Hydrogen Sulfide and Nitric Oxide. |
| Q35217368 | Sepiapterin improves angiogenesis of pulmonary artery endothelial cells with in utero pulmonary hypertension by recoupling endothelial nitric oxide synthase |
| Q35839144 | Serine 1179 Phosphorylation of Endothelial Nitric Oxide Synthase Increases Superoxide Generation and Alters Cofactor Regulation |
| Q37728516 | Sesamin ameliorates arterial dysfunction in spontaneously hypertensive rats via downregulation of NADPH oxidase subunits and upregulation of eNOS expression |
| Q58075704 | Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation |
| Q36253833 | Superoxide generation by endothelial nitric oxide synthase: the influence of cofactors |
| Q35865615 | Syringaresinol causes vasorelaxation by elevating nitric oxide production through the phosphorylation and dimerization of endothelial nitric oxide synthase |
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| Q47749537 | The protein inhibitor of neuronal nitric oxide synthase (PIN): characterization of its action on pure nitric oxide synthases |
| Q43011251 | The return of the Scarlet Pimpernel: cobalamin in inflammation II - cobalamins can both selectively promote all three nitric oxide synthases (NOS), particularly iNOS and eNOS, and, as needed, selectively inhibit iNOS and nNOS. |
| Q64058332 | Use of Computational Biochemistry for Elucidating Molecular Mechanisms of Nitric Oxide Synthase |
| Q50294435 | eNOS synthesizes NO |
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