The Oct-2 transcription factor represses tyrosine hydroxylase expression via a heptamer TAATGARAT-like motif in the gene promoter

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The Oct-2 transcription factor represses tyrosine hydroxylase expression via a heptamer TAATGARAT-like motif in the gene promoter is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/NAR/22.6.1023
P932PMC publication ID307925
P698PubMed publication ID7908738
P5875ResearchGate publication ID15289971

P2093author name stringD. M. Chikaraishi
D. S. Latchman
S. O. Yoon
S. J. Dawson
K. A. Lillycrop
P2860cites workEstablishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factorQ24561804
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Expression of a large family of POU-domain regulatory genes in mammalian brain developmentQ28277007
Octamer transcription factors bind to two different sequence motifs of the immunoglobulin heavy chain promoterQ33569207
A family of octamer-specific proteins present during mouse embryogenesis: evidence for germline-specific expression of an Oct factorQ33575964
Transcriptional regulation of the tyrosine hydroxylase gene by glucocorticoid and cyclic AMPQ34626064
Identification and characterization of mRNAs regulated by nerve growth factor in PC12 cellsQ36472638
Octamer transcription factors 1 and 2 each bind to two different functional elements in the immunoglobulin heavy-chain promoterQ36766587
Regulated expression of the tyrosine hydroxylase gene by epidermal growth factorQ36921522
Current status review: molecular biology of herpes simplex virus latencyQ37873737
A novel POU family transcription factor is closely related to Brn-3 but has a distinct expression pattern in neuronal cellsQ38325341
Sequences that direct rat tyrosine hydroxylase gene expressionQ38328529
The octamer-binding protein Oct-2 represses HSV immediate-early genes in cell lines derived from latently infectable sensory neuronsQ38333663
Herpes simplex virus regulatory elements and the immunoglobulin octamer domain bind a common factor and are both targets for virion transactivationQ38347799
A complex formed between cell components and an HSV structural polypeptide binds to a viral immediate early gene regulatory DNA sequenceQ38347804
An inquiry into the mechanisms of herpes simplex virus latencyQ39159400
A procedure to standardize CAT reporter gene assayQ40423199
A series of mammalian expression vectors and characterisation of their expression of a reporter gene in stably and transiently transfected cellsQ40514473
Multiple Oct2 isoforms are generated by alternative splicingQ40530633
Oct2 transactivation from a remote enhancer position requires a B-cell-restricted activityQ40655422
Alternative splicing of the Oct-2 transcription factor RNA is differentially regulated in neuronal cells and B cells and results in protein isoforms with opposite effects on the activity of octamer/TAATGARAT-containing promotersQ41589861
Elevation of cyclic AMP levels in cell lines derived from latently infectable sensory neurons increases their permissivity for herpes virus infection by activating the viral immediate-early 1 gene promoterQ41649146
Intracellular redistribution of neuropeptides and secretory proteins during differentiation of neuronal cell linesQ41649999
The B-cell and neuronal forms of the octamer-binding protein Oct-2 differ in DNA-binding specificity and functional activityQ41670378
Epidermal growth factor induces, in the ELα4−2 cell line, herpes simplex virus-1 α4 gene transcription in the absence of the viral trans-activator VP16Q41686775
Nerve growth factor regulates tyrosine hydroxylase gene transcription through a nucleoprotein complex that contains c-FosQ41739550
Octamer motif mediates transcriptional repression of HSV immediate-early genes and octamer-containing cellular promoters in neuronal cellsQ44617921
Effect of chronic cold exposure on tyrosine hydroxylase mRNA in rat adrenal glandQ48426973
Induction of tyrosine hydroxylase in peripheral and central adrenergic neurones by cold-exposure of ratsQ48882599
Tissue-specific transcription of the rat tyrosine hydroxylase gene requires synergy between an AP-1 motif and an overlapping E box-containing dyadQ52477677
Polyoma transformation of hamster cell clones—an investigation of genetic factors affecting cell competenceQ52828028
Novel cell lines display properties of nociceptive sensory neurons.Q53505102
A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genesQ59066385
A lymphoid-specific protein binding to the octamer motif of immunoglobulin genesQ59067785
5' flanking DNA sequences direct cell-specific expression of rat tyrosine hydroxylaseQ69374514
Identification and purification of a human lymphoid-specific octamer-binding protein (OTF-2) that activates transcription of an immunoglobulin promoter in vitroQ70366236
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)1023–1028
P577publication date1994-03-25
P1433published inNucleic Acids ResearchQ135122
P1476titleThe Oct-2 transcription factor represses tyrosine hydroxylase expression via a heptamer TAATGARAT-like motif in the gene promoter
P478volume22

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cites work (P2860)
Q37135184A high throughput embryonic stem cell screen identifies Oct-2 as a bifunctional regulator of neuronal differentiation
Q40208283A novel role for Oct-2 in the lipopolysaccharide-mediated induction of resistin gene expression in RAW264.7 cells.
Q28575401A response element for the homeodomain transcription factor Ptx3 in the tyrosine hydroxylase gene promoter
Q37029654A tyrosine hydroxylase-yellow fluorescent protein knock-in reporter system labeling dopaminergic neurons reveals potential regulatory role for the first intron of the rodent tyrosine hydroxylase gene.
Q39723868Adjacent proline residues in the inhibitory domain of the Oct-2 transcription factor play distinct functional roles.
Q41033506Cell type specific repression of the varicella zoster virus immediate early gene 62 promoter by the cellular Oct-2 transcription factor
Q24813402DNA-dependent conversion of Oct-1 and Oct-2 into transcriptional repressors by Groucho/TLE
Q41071869Differential regulation of genes encoding synaptic proteins by the Oct-2 transcription factor
Q41145406Differential regulation of the two neuronal nitric-oxide synthase gene promoters by the Oct-2 transcription factor
Q41385551Direct evidence that the POU family transcription factor Oct-2 represses the cellular tyrosine hydroxylase gene in neuronal cells
Q35391761Lipopolysaccharide regulation of lipoprotein lipase expression in murine macrophages
Q41060764Lithium increases melanin-concentrating hormone mRNA stability and inhibits tyrosine hydroxylase gene expression in PC12 cells
Q31878412Nerve growth factor down-regulates the expression of norepinephrine transporter in rat pheochromocytoma (PC12) cells
Q38899516Nucleotide sequence conservation of novel and established cis-regulatory sites within the tyrosine hydroxylase gene promoter
Q28210630Orphanin FQ/nociceptin blocks chronic morphine-induced tyrosine hydroxylase upregulation
Q41431521Repression of a herpes simplex virus immediate-early promoter by the Oct-2 transcription factor is dependent on an inhibitory region at the N terminus of the protein
Q41295039The Cyclic AMP Response Element Directs Tyrosine Hydroxylase Expression in Catecholaminergic Central and Peripheral Nervous System Cell Lines from Transgenic Mice
Q28507351The ability of POU family transcription factors to activate or repress gene expression is dependent on the spacing and context of their specific response elements
Q42519829The ability of the inhibitory domain of the POU family transcription factor Oct-2 to interfere with promoter activation by different classes of activation domains is dependent upon the nature of the basal promoter elements
Q40394319The chicken immunoglobulin λ light chain gene is transcriptionally controlled by a modularly organized enhancer and an octamer-dependent silencer
Q77741483The different alternatively spliced isoforms of the Oct-2 transcription factor repress the involucrin promoter in a cell type-specific manner
Q38341690The different inhibitory domains of the Oct-2 transcription factor have distinct functional activities
Q41387568The inhibitory domain in the Oct-2 transcription factor represses gene activity in a cell type-specific and promoter-independent manner
Q40964411The regulation of neuron-specific gene expression in the mammalian nervous system.
Q28576766ZENON, a novel POZ Kruppel-like DNA binding protein associated with differentiation and/or survival of late postmitotic neurons

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