Adjacent proline residues in the inhibitory domain of the Oct-2 transcription factor play distinct functional roles.

scientific article published on May 1998

Adjacent proline residues in the inhibitory domain of the Oct-2 transcription factor play distinct functional roles. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/NAR/26.10.2464
P932PMC publication ID147571
P698PubMed publication ID9580701
P5875ResearchGate publication ID13702774

P50authorSally J. DawsonQ39184132
Ian C LockeQ60315373
P2093author name stringD S Latchman
I K Lee
Y Z Liu
P2860cites workMultiple nuclear factors interact with the immunoglobulin enhancer sequencesQ24296245
Transcriptional repression by YY1, a human GLI-Krüppel-related protein, and relief of repression by adenovirus E1A proteinQ24309481
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Expression of a large family of POU-domain regulatory genes in mammalian brain developmentQ28277007
Oct-2, although not required for early B-cell development, is critical for later B-cell maturation and for postnatal survivalQ28513024
The Oct-2 transcription factor represses tyrosine hydroxylase expression via a heptamer TAATGARAT-like motif in the gene promoterQ28645925
Mechanism of transcriptional activation by Sp1: evidence for coactivatorsQ29620214
A vector for expressing GAL4(1-147) fusions in mammalian cellsQ29620516
A family of octamer-specific proteins present during mouse embryogenesis: evidence for germline-specific expression of an Oct factorQ33575964
Transcription factor Oct-2A contains functionally redundant activating domains and works selectively from a promoter but not from a remote enhancer position in non-lymphoid (HeLa) cellsQ33919791
The cell type-specific octamer transcription factor OTF-2 has two domains required for the activation of transcriptionQ33919795
Interaction of positive and negative regulatory proteins in the galactose regulon of yeastQ34172943
Transcriptional repression by the human bZIP factor E4BP4: definition of a minimal repression domainQ34798810
11q23 translocations split the "AT-hook" cruciform DNA-binding region and the transcriptional repression domain from the activation domain of the mixed-lineage leukemia (MLL) geneQ35865236
Cloning of a Lymphoid-Specific cDNA Encoding a Protein Binding the Regulatory Octamer DNA MotifQ36454242
CRISP-3, a protein with homology to plant defense proteins, is expressed in mouse B cells under the control of Oct2Q36563487
Mapping and mutagenesis of the amino-terminal transcriptional repression domain of the Drosophila Krüppel proteinQ36655046
Krüppel-associated box-mediated repression of RNA polymerase II promoters is influenced by the arrangement of basal promoter elementsQ37727809
Transcriptional activation and repression, two properties of the lymphoid-specific transcription factor Oct-2aQ38289155
Identification of CD36 as the first gene dependent on the B-cell differentiation factor Oct-2.Q38293977
Transcriptional repression by the Drosophila even-skipped protein: definition of a minimal repression domainQ38321359
The octamer-binding protein Oct-2 represses HSV immediate-early genes in cell lines derived from latently infectable sensory neuronsQ38333663
The different inhibitory domains of the Oct‐2 transcription factor have distinct functional activitiesQ38341690
A Domain of the even-skipped Protein Represses Transcription by Preventing TFIID Binding to a Promoter: Repression by Cooperative BlockingQ40017010
A procedure to standardize CAT reporter gene assayQ40423199
Functional differences between the Oct2 transactivation domains determine the transactivation potential of individual Oct2 isoformsQ40522431
Multiple Oct2 isoforms are generated by alternative splicingQ40530633
Repression versus activation in the control of gene transcriptionQ40731530
POU-domain proteins: structure and function of developmental regulatorsQ40835507
POU domain transcription factorsQ40902978
Differential regulation of genes encoding synaptic proteins by the Oct-2 transcription factorQ41071869
Active repression mechanisms of eukaryotic transcription repressorsQ41223932
The inhibitory domain in the Oct-2 transcription factor represses gene activity in a cell type-specific and promoter-independent mannerQ41387568
Repression of a herpes simplex virus immediate-early promoter by the Oct-2 transcription factor is dependent on an inhibitory region at the N terminus of the proteinQ41431521
Alternative splicing of the Oct-2 transcription factor RNA is differentially regulated in neuronal cells and B cells and results in protein isoforms with opposite effects on the activity of octamer/TAATGARAT-containing promotersQ41589861
The B-cell and neuronal forms of the octamer-binding protein Oct-2 differ in DNA-binding specificity and functional activityQ41670378
The ability of the inhibitory domain of the POU family transcription factor Oct-2 to interfere with promoter activation by different classes of activation domains is dependent upon the nature of the basal promoter elementsQ42519829
Structure and expression of the mouse Oct2a and Oct2b, two differentially spliced products of the same geneQ42626119
A structure-function analysis of transcriptional repression mediated by the WT1, Wilms' tumor suppressor proteinQ42808343
Octamer motif mediates transcriptional repression of HSV immediate-early genes and octamer-containing cellular promoters in neuronal cellsQ44617921
Short-range repression permits multiple enhancers to function autonomously within a complex promoterQ46159465
Mini-Oct and Oct-2c: two novel, functionally diverse murine Oct-2 gene products are differentially expressed in the CNSQ48517170
Polyoma transformation of hamster cell clones—an investigation of genetic factors affecting cell competenceQ52828028
Novel cell lines display properties of nociceptive sensory neuronsQ53505102
New eukaryotic transcriptional repressors.Q54655807
A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genesQ59066385
The oncogenic transcription factor IRF-2 possesses a transcriptional repression and a latent activation domainQ72351854
P433issue10
P407language of work or nameEnglishQ1860
P1104number of pages9
P304page(s)2464-2472
P577publication date1998-05-01
P1433published inNucleic Acids ResearchQ135122
P1476titleAdjacent proline residues in the inhibitory domain of the Oct-2 transcription factor play distinct functional roles
P478volume26

Reverse relations

cites work (P2860)
Q58010999Analysis of Octamer-Binding Transcription Factors Oct2 and Oct1 and their coactivator BOB.1/OBF.1 in Lymphomas
Q38325198Distinct responses of the herpes simplex virus and varicella zoster virus immediate early promoters to the cellular transcription factors Brn-3a and Brn-3b
Q44070723Oct2 transcription factor of a teleost fish: activation domains and function from an enhancer
Q40912238Regulation of the Wilms' tumour suppressor protein transcriptional activation domain.

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