Mapping and mutagenesis of the amino-terminal transcriptional repression domain of the Drosophila Krüppel protein

scientific article published on June 1994

Mapping and mutagenesis of the amino-terminal transcriptional repression domain of the Drosophila Krüppel protein is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.14.6.4057
P932PMC publication ID358771
P698PubMed publication ID8196644
P5875ResearchGate publication ID15001910

P2093author name stringU Hansen
J C Reddy
J D Licht
M A English
M Grossel
M Ro
R Shaknovich
W Hanna-Rose
P2860cites workTranscriptional repression by YY1, a human GLI-Krüppel-related protein, and relief of repression by adenovirus E1A proteinQ24309481
Dr1, a TATA-binding protein-associated phosphoprotein and inhibitor of class II gene transcriptionQ24337785
A transferable silencing domain is present in the thyroid hormone receptor, in the v-erbA oncogene product and in the retinoic acid receptorQ24555696
A comprehensive set of sequence analysis programs for the VAXQ26778432
Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cellsQ27860607
Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteinsQ27861094
Ssn6-Tup1 is a general repressor of transcription in yeastQ27933537
The Wilms' tumor gene product WT1 activates or suppresses transcription through separate functional domainsQ28268839
A novel repression module, an extensive activation domain, and a bipartite nuclear localization signal defined in the immediate-early transcription factor Egr-1Q28507452
Correlative changes in homoeotic and segmentation gene expression in Krüppel mutant embryos of DrosophilaQ28972568
Five intermediate complexes in transcription initiation by RNA polymerase IIQ29616444
The human estrogen receptor has two independent nonacidic transcriptional activation functionsQ29617089
Mechanism of transcriptional activation by Sp1: evidence for coactivatorsQ29620214
Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motifQ29620290
Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected of coactivatorsQ29620376
Genetic isolation of ADA2: a potential transcriptional adaptor required for function of certain acidic activation domainsQ29620928
Expression of the Wilms' tumor gene WT1 in the murine urogenital systemQ33235262
Analysis of the creA gene, a regulator of carbon catabolite repression in Aspergillus nidulansQ33409712
Three hormone receptor-like Drosophila genes encode an identical DNA-binding fingerQ33581570
Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expressionQ34555693
Activities of herpes simplex virus type 1 (HSV-1) ICP4 genes specifying nonsense peptidesQ36129181
Drosophila transcriptional repressor protein that binds specifically to negative control elements in fat body enhancersQ36701143
Selective repression of transcriptional activators at a distance by the Drosophila Krüppel proteinQ36702540
Making stripes in the Drosophila embryoQ37989587
Sequence-specific DNA-binding activities of the gap proteins encoded by hunchback and Krüppel in DrosophilaQ38235594
The Wilms tumour gene WT1 is expressed in murine mesoderm-derived tissues and mutated in a human mesotheliomaQ38317044
Transcriptional repression by the Drosophila even-skipped protein: definition of a minimal repression domainQ38321359
Differential regulation of transcription preinitiation complex assembly by activator and repressor homeo domain proteinsQ38324897
Regulation of a Segmentation Stripe by Overlapping Activators and Repressors in the Drosophila EmbryoQ38332149
Distinct classes of transcriptional activating domains function by different mechanismsQ38339126
Transcriptional repression of eukaryotic promotersQ38365817
Fused protein domains inhibit DNA binding by LexAQ40655370
Human growth hormone as a reporter gene in regulation studies employing transient gene expressionQ40667158
A novel spatial transcription pattern associated with the segmentation gene, giant, of DrosophilaQ40817942
Functional domains of the Drosophila Engrailed proteinQ40873357
Active repression of transcription by the engrailed homeodomain proteinQ41080980
The tramtrack gene encodes a Drosophila finger protein that interacts with the ftz transcriptional regulatory region and shows a novel embryonic expression patternQ41200733
Characterization and localization of the even-skipped protein of DrosophilaQ41336342
NGFIA (EGR1) contains transcription activating domains in both the amino terminal and carboxyl terminal regions of the proteinQ41541701
Cooperative binding at a distance by even-skipped protein correlates with repression and suggests a mechanism of silencingQ41557831
Concentration-dependent transcriptional activation or repression by Krüppel from a single binding siteQ41661390
Transcriptional repression mediated by the WT1 Wilms tumor gene productQ41661461
Mitochondrial targeting sequences may form amphiphilic helicesQ41980390
Activation of RNA polymerase II transcription by the specific DNA-binding protein LSF. Increased rate of binding of the basal promoter factor TFIIBQ42450943
A structure-function analysis of transcriptional repression mediated by the WT1, Wilms' tumor suppressor proteinQ42808343
The giant gene of Drosophila encodes a b-ZIP DNA-binding protein that regulates the expression of other segmentation gap genes.Q44772556
Krüppel requirement for knirps enhancement reflects overlapping gap gene activities in the Drosophila embryoQ45757474
Activation and repression of transcription by the gap proteins hunchback and Krüppel in cultured Drosophila cellsQ47070058
The products of the Drosophila gap genes hunchback and Krüppel bind to the hunchback promotersQ47071709
Altered trans-activational properties of a mutated WT1 gene product in a WAGR-associated Wilms' tumor.Q52032594
Transcriptional regulation of a pair-rule stripe in Drosophila.Q52448278
Drosophila Krüppel protein is a transcriptional repressor.Q52449047
Analysis of maternal effect mutant combinations elucidates regulation and function of the overlap of hunchback and Krüppel gene expression in the Drosophila blastoderm embryo.Q52454106
The zygotic control of Drosophila pair-rule gene expression. II. Spatial repression by gap and pair-rule gene products.Q52454108
Early and late periodic patterns of even skipped expression are controlled by distinct regulatory elements that respond to different spatial cues.Q52454785
Dimerization and the control of transcription by Krüppel.Q52544832
Reduced binding of TFIID to transcriptionally compromised mutants of VP16.Q54251780
Lac repressor can regulate expression from a hybrid SV40 early promoter containing a lac operator in animal cellsQ57165937
Evidence for interaction of different eukaryotic transcriptional activators with distinct cellular targetsQ59098114
Steroid hormone receptors compete for factors that mediate their enhancer functionQ61818663
The carboxyl-terminal two-thirds of the ADP/ATP carrier polypeptide contains sufficient information to direct translocation into mitochondriaQ62996735
Stringent regulation of stably integrated chloramphenicol acetyl transferase genes by E. coli lac repressor in monkey cellsQ69820086
Mechanism of action of an acidic transcriptional activator in vitroQ70113517
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectDrosophilaQ312154
P304page(s)4057-4066
P577publication date1994-06-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleMapping and mutagenesis of the amino-terminal transcriptional repression domain of the Drosophila Krüppel protein
P478volume14

Reverse relations

cites work (P2860)
Q40017010A Domain of the even-skipped Protein Represses Transcription by Preventing TFIID Binding to a Promoter: Repression by Cooperative Blocking
Q24324110A mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domains
Q39723868Adjacent proline residues in the inhibitory domain of the Oct-2 transcription factor play distinct functional roles.
Q34494994An investigation into FOXE1 polyalanine tract length in premature ovarian failure.
Q39540142Cell signaling switches HOX-PBX complexes from repressors to activators of transcription mediated by histone deacetylases and histone acetyltransferases.
Q28586035Characterization of a new subfamily of winged-helix/forkhead (Fox) genes that are expressed in the lung and act as transcriptional repressors
Q36126259Coding repeats and evolutionary "agility".
Q45790418Contribution of ATM and FOXE1 (TTF2) to risk of papillary thyroid carcinoma in Belarusian children exposed to radiation
Q39753318CtBP-independent repression in the Drosophila embryo
Q52680114Direct interaction between Teashirt and Sex combs reduced proteins, via Tsh's acidic domain, is essential for specifying the identity of the prothorax in Drosophila.
Q34055643EVOPRINTER, a multigenomic comparative tool for rapid identification of functionally important DNA
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Q22254377Expression and function of the homeodomain-containing protein Hex in thyroid cells
Q24324921FKHL15, a new human member of the forkhead gene family located on chromosome 9q22
Q35777265FOXE1 polyalanine tract length screening by MLPA in idiopathic premature ovarian failure
Q44509755Functional analysis of RF2a, a rice transcription factor
Q43185240Genome-wide analysis of ethylene-responsive element binding factor-associated amphiphilic repression motif-containing transcriptional regulators in Arabidopsis.
Q35196294Groucho acts as a corepressor for a subset of negative regulators, including Hairy and Engrailed
Q28201271Human HOX gene mutations
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Q24311650Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor
Q28204788Limb malformations and the human HOX genes
Q38356590Mapping of the transcriptional repression domain of the lymphoid-specific transcription factor oct-2A.
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Q24561871Net (ERP/SAP2) one of the Ras-inducible TCFs, has a novel inhibitory domain with resemblance to the helix-loop-helix motif
Q42609875Polymorphism, shared functions and convergent evolution of genes with sequences coding for polyalanine domains
Q28586979Repression by HoxA7 is mediated by the homeodomain and the modulatory action of its N-terminal-arm residues
Q46609747Repressor domain and nuclear localization signal of the murine Hoxa-11 protein are located in the homeodomain: no evidence for role of poly alanine stretches in transcriptional repression.
Q34462681Rex-1, a gene encoding a transcription factor expressed in the early embryo, is regulated via Oct-3/4 and Oct-6 binding to an octamer site and a novel protein, Rox-1, binding to an adjacent site
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Q40023103Two evolutionarily conserved repression domains in the Drosophila Kruppel protein differ in activator specificity
Q52173204hairy stripe 7 element mediates activation and repression in response to different domains and levels of Krüppel in the Drosophila embryo.

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