| scholarly article | Q13442814 |
| P819 | ADS bibcode | 1991Sci...253.1550M |
| P356 | DOI | 10.1126/SCIENCE.1654597 |
| P698 | PubMed publication ID | 1654597 |
| P2093 | author name string | Cook DM | |
| Morris JF | |||
| Sukhatme VP | |||
| Rauscher FJ 3rd | |||
| Madden SL | |||
| Gashler A | |||
| P433 | issue | 5027 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | nephroblastoma | Q756289 |
| P304 | page(s) | 1550-1553 | |
| P577 | publication date | 1991-09-01 | |
| P1433 | published in | Science | Q192864 |
| P1476 | title | Transcriptional repression mediated by the WT1 Wilms tumor gene product | |
| P478 | volume | 253 |
| Q36555764 | 12-O-tetradecanoylphorbol-13-acetate activation of the MDR1 promoter is mediated by EGR1 |
| Q33722731 | 15(S)-hydroxyeicosatetraenoic acid-induced angiogenesis requires Src-mediated Egr-1-dependent rapid induction of FGF-2 expression. |
| Q40017010 | A Domain of the even-skipped Protein Represses Transcription by Preventing TFIID Binding to a Promoter: Repression by Cooperative Blocking |
| Q73959899 | A Far Upstream Cis-element Is Required for Wilms' Tumor-1 (WT1) Gene Expression in Renal Cell Culture |
| Q42830606 | A functional interaction with CBP contributes to transcriptional activation by the Wilms tumor suppressor WT1. |
| Q28507452 | A novel repression module, an extensive activation domain, and a bipartite nuclear localization signal defined in the immediate-early transcription factor Egr-1 |
| Q24324095 | A novel repressor, par-4, modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1 |
| Q24290116 | A novel zinc finger gene is fused to EWS in small round cell tumor |
| Q71046703 | A nude mouse Wilms' tumor line (KCMC-WT-1) derived from an aniridia patient with monoalleleic partial deletion of chromosome 11p |
| Q36560249 | A second transcriptionally active DNA-binding site for the Wilms tumor gene product, WT1 |
| Q39431426 | Abnormal gonadal differentiation in two subjects with ambiguous genitalia, Mullerian structures, and normally developed testes: evidence for a defect in gonadal ridge development |
| Q77395024 | Allelic Losses at 3p and 11p Are Detected in Both Epithelial and Stromal Components of Cervical Small-Cell Neuroendocrine Carcinoma |
| Q46867713 | Alternative splicing of Wilms tumor suppressor 1 (Wt1) exon 4 results in protein isoforms with different functions |
| Q34107313 | Amine oxidase copper-containing 1 (AOC1) is a downstream target gene of the Wilms tumor protein, WT1, during kidney development |
| Q36987464 | Analysis of Egr-1 protein induction in murine peritoneal macrophages treated with granulocyte-macrophage colony-stimulating factor |
| Q52200034 | Analysis of WT1 gene expression during mouse nephrogenesis in organ culture |
| Q40578390 | Anlaysis of complementary expression profiles following WT1 induction versus repression reveals the cholesterol/fatty acid synthetic pathways as a possible major target of WT1. |
| Q52182053 | Antisense WT1 transcription parallels sense mRNA and protein expression in fetal kidney and can elevate protein levels in vitro |
| Q34141348 | Astrocyte growth is regulated by neuropeptides through Tis 8 and basic fibroblast growth factor |
| Q63722729 | Autoregulation of the human WT1 gene promoter |
| Q24303633 | BASP1 is a transcriptional cosuppressor for the Wilms' tumor suppressor protein WT1 |
| Q35716500 | Beckwith-Wiedemann syndrome, tumourigenesis and imprinting |
| Q34160093 | Biochemical function of female-lethal (2)D/Wilms' tumor suppressor-1-associated proteins in alternative pre-mRNA splicing. |
| Q41258141 | C-jun and Egr-1 participate in DNA synthesis and cell survival in response to ionizing radiation exposure |
| Q38356832 | Casein kinase II associates with Egr-1 and acts as a negative modulator of its DNA binding and transcription activities in NIH 3T3 cells |
| Q34676847 | Characterization of the genomic breakpoint and chimeric transcripts in the EWS-WT1 gene fusion of desmoplastic small round cell tumor |
| Q24309269 | Ciao 1 Is a Novel WD40 Protein That Interacts with the Tumor Suppressor Protein WT1 |
| Q33847590 | Classification of a frameshift/extended and a stop mutation in WT1 as gain-of-function mutations that activate cell cycle genes and promote Wilms tumour cell proliferation |
| Q24300285 | Cloning of six new genes with zinc finger motifs mapping to short and long arms of human acrocentric chromosome 22 (p and q11.2) |
| Q24312939 | Cloning of two human homologs of the Drosophila single-minded gene SIM1 on chromosome 6q and SIM2 on 21q within the Down syndrome chromosomal region |
| Q24313408 | Comparative in situ hybridization analysis of PAX2, PAX8, and WT1 gene transcription in human fetal kidney and Wilms' tumors |
| Q40722269 | Comparative study and identification of potent eukaryotic transcriptional repressors in gene switch systems |
| Q40411319 | Compilation of vertebrate-encoded transcription factors |
| Q48402697 | Control by thyroid hormone of NGFI-A gene expression in lung: regulation of NGFI-A promoter activity |
| Q38323986 | CpG oligodeoxynucleotides rescue BKS-2 immature B cell lymphoma from anti-IgM-mediated growth inhibition by up-regulation of egr-1. |
| Q41159629 | DNA binding by cut homeodomain proteins is down-modulated by protein kinase C. |
| Q38307463 | DNA recognition by splicing variants of the Wilms' tumor suppressor, WT1 |
| Q38331264 | Desmoplastic small round cell tumor: RT-PCR analysis and immunohistochemical detection of the Wilm's tumor gene WT1. |
| Q40844070 | Detection of a novel truncated WT1 transcript in human neoplasia |
| Q46127565 | Differential Effects of Wilms Tumor WT1 Splice Variants on the Insulin Receptor Promoter |
| Q38359162 | Differential function of Wilms' tumor gene WT1 splice isoforms in transcriptional regulation |
| Q36855682 | Divergent transforming growth factor-beta signaling in hepatic stellate cells after liver injury: functional effects on ECE-1 regulation |
| Q41645473 | Diverse aspects of metanephric development |
| Q40716988 | Downregulation of Wilms' tumor 1 protein inhibits breast cancer proliferation |
| Q38351455 | EGR-1 induction is required for maximal radiosensitivity in A375-C6 melanoma cells |
| Q90558495 | EGR-mediated control of STIM expression and function |
| Q41094563 | Early Growth Response-1-dependent Apoptosis Is Mediated by p53 |
| Q39984972 | Early growth response-1 mediates downregulation of telomerase in cervical cancer |
| Q40881914 | Egr transcription factors in the nervous system |
| Q40663928 | Egr-1 mediates transcriptional repression of COL2A1 promoter activity by interleukin-1beta |
| Q33744636 | Embryonic renal epithelia: induction, nephrogenesis, and cell differentiation |
| Q39874105 | Epstein-Barr virus nuclear antigen 3C is a powerful repressor of transcription when tethered to DNA. |
| Q24562189 | Evidence for physical interaction between the zinc-finger transcription factors YY1 and Sp1 |
| Q33352317 | Evolutionary conservation of zinc finger transcription factor binding sites in promoters of genes co-expressed with WT1 in prostate cancer |
| Q70467482 | Exon skipping due to a mutation in a donor splice site in the WT-1 gene is associated with Wilms' tumor and severe genital malformations |
| Q22254377 | Expression and function of the homeodomain-containing protein Hex in thyroid cells |
| Q36569185 | Expression and function of the leucine zipper protein Par-4 in apoptosis |
| Q71683706 | Expression of the Wilms' tumor gene WT1 in human malignant mesothelioma cell lines and relationship to platelet-derived growth factor A and insulin-like growth factor 2 expression |
| Q36136599 | Expression of the zinc finger gene EVI-1 in ovarian and other cancers |
| Q24305390 | Expression, regulation, and function of paired-box gene 8 in the human placenta and placental cancer cell lines |
| Q39805402 | Fluid shear stress activation of egr-1 transcription in cultured human endothelial and epithelial cells is mediated via the extracellular signal-related kinase 1/2 mitogen-activated protein kinase pathway |
| Q58741373 | From repression domains to designer zinc finger proteins: a novel strategy of intracellular immunization against HIV |
| Q44509755 | Functional analysis of RF2a, a rice transcription factor |
| Q40759660 | Functional characterization of WT1 binding sites within the human vitamin D receptor gene promoter |
| Q40873357 | Functional domains of the Drosophila Engrailed protein |
| Q34341142 | G1 phase arrest induced by Wilms tumor protein WT1 is abrogated by cyclin/CDK complexes |
| Q72019485 | Gene Expression After Uninephrectomy in Rat: Simultaneous Expression of Positive and Negative Growth Control Elements |
| Q41127738 | Gene targeting in kidney development |
| Q34783505 | Genetic insights into familial cancers-- update and recent discoveries |
| Q72539974 | Genetics of Wilms' tumor: a blend of aberrant development and genomic imprinting |
| Q81510539 | Genome-wide loss of heterozygosity analysis of WT1-wild-type and WT1-mutant Wilms tumors |
| Q55261006 | Genomic organization of the human WT1 gene |
| Q71580257 | Genotype/phenotype correlations in Wilms' tumor |
| Q52231802 | Germline intronic and exonic mutations in the Wilms' tumour gene (WT1) affecting urogenital development |
| Q24648833 | Gfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressor |
| Q24314245 | High affinity binding sites for the Wilms' tumour suppressor protein WT1 |
| Q52035238 | Homozygous inactivation of WT1 in a Wilms' tumor associated with the WAGR syndrome |
| Q24318678 | Human EZF, a Krüppel-like zinc finger protein, is expressed in vascular endothelial cells and contains transcriptional activation and repression domains |
| Q24337538 | Human platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1 |
| Q42454924 | Identification of a key regulatory element for the basal activity of the human insulin-like growth factor II gene promoter P3 |
| Q27933753 | Identification of cis-acting elements in the SUC2 promoter of Saccharomyces cerevisiae required for activation of transcription |
| Q30482686 | In silico regulatory analysis for exploring human disease progression |
| Q36378010 | Increased expression of the insulin-like growth factor I receptor gene, IGF1R, in Wilms tumor is correlated with modulation of IGF1R promoter activity by the WT1 Wilms tumor gene product |
| Q22003911 | Induction of Rb-associated Protein (RbAp46) by Wilms' Tumor Suppressor WT1 Mediates Growth Inhibition |
| Q58298619 | Infrequent mutation of theWT1 gene in 77 Wilms' tumors |
| Q33961993 | Inherited renal cancer |
| Q36552308 | Inhibition of cellular proliferation by the Wilms' tumor suppressor WT1 is associated with suppression of insulin-like growth factor I receptor gene expression |
| Q42243631 | Inserting the Ftz homeodomain into Engrailed creates a dominant transcriptional repressor that specifically turns off Ftz target genes in vivo |
| Q41578756 | Involvement of immediate-early gene expression in the synergistic effects of steel factor in combination with granulocyte-macrophage colony-stimulating factor or interleukin-3 on proliferation of a human factor-dependent cell line |
| Q73959969 | Ionizing Radiation-inducible Apoptosis in the Absence of p53 Linked to Transcription Factor EGR-1 |
| Q73086119 | Ionizing radiation down-regulates p53 protein in primary Egr-1-/- mouse embryonic fibroblast cells causing enhanced resistance to apoptosis |
| Q24337444 | Isolation and Characterization of a Novel Zinc-finger Protein with Transcriptional Repressor Activity |
| Q24563259 | Krüppel-associated boxes are potent transcriptional repression domains |
| Q24317124 | Leucine-zipper dimerization motif encoded by the AF17 gene fused to ALL-1 (MLL) in acute leukemia |
| Q36081181 | Loss of heterozygosity at chromosome 11 in breast cancer: association of prognostic factors with genetic alterations |
| Q71601023 | Low frequency of mutations in the WT1 coding region in Wilms' tumor |
| Q36655046 | Mapping and mutagenesis of the amino-terminal transcriptional repression domain of the Drosophila Krüppel protein |
| Q40422361 | Mapping functional regions of the segment-specific transcription factor Krox-20. |
| Q38313230 | Mechanical stretch modulates the promoter activity of the profibrotic factor CCN2 through increased actin polymerization and NF-kappaB activation |
| Q48067012 | Mechanisms identified in the transcriptional control of epithelial gene expression |
| Q74736163 | Molecular Genetics of Renal Cell Carcinoma |
| Q40383506 | Molecular advances in pediatric urology |
| Q72743284 | Molecular analysis of two Japanese cases of Denys-Drash syndrome |
| Q24314790 | Molecular cloning of a novel human cDNA encoding a zinc finger protein that binds to the interleukin-3 promoter |
| Q34051653 | Molecular genetics of chromosome translocations involving EWS and related family members |
| Q41584835 | Molecular organization of the rat glia-derived nexin/protease nexin-1 promoter. |
| Q77803712 | Molecular regulation of pronephric development |
| Q74320034 | Morphologic Changes Suggesting Abnormal Renal Differentiation in Congenital Nephrotic Syndrome |
| Q52531672 | Multiple roles for the Wilms' tumour suppressor gene, WT1 in genitourinary development |
| Q33595792 | Mutational screening of the Wilms's tumour gene, WT1, in males with genital abnormalities |
| Q35716604 | Mutations in signal transduction pathways and inherited diseases |
| Q28144228 | Myelin deficiencies in both the central and the peripheral nervous systems associated with a SOX10 mutation |
| Q40800435 | Negative regulation of transcription in eukaryotes |
| Q37127104 | New insights into the function of the Wilms tumor suppressor gene WT1 in podocytes |
| Q38304872 | Novel negative regulatory element in the platelet-derived growth factor B chain promoter that mediates ERK-dependent transcriptional repression. |
| Q44644325 | Nuclear transport of Wilms' tumour protein Wt1 involves importins α and β. |
| Q42667055 | Nucleotide sequence and cell cycle-associated differential expression of ZF5128, a novel Kruppel type zinc finger protein gene |
| Q24609798 | PRDI-BF1/Blimp-1 repression is mediated by corepressors of the Groucho family of proteins |
| Q28346512 | Par4 is a coactivator for a splice isoform-specific transcriptional activation domain in WT1 |
| Q40397351 | Perspectives on zinc finger protein function and evolution--an update |
| Q24522630 | Phosphorylation of Nuclear MyoD Is Required for Its Rapid Degradation |
| Q28575245 | Physical and functional interaction between WT1 and p53 proteins |
| Q52183896 | Precocious Expression of the Wilms' Tumor GenexWT1Inhibits Embryonic Kidney Development inXenopus laevis |
| Q34031394 | Principles of Wilms' tumor biology |
| Q35188770 | Promiscuous partnerships in Ewing's sarcoma |
| Q42818627 | Protein phosphatase inhibitors induce the sustained expression of the Egr-1 gene and the hyperphosphorylation of its gene product |
| Q24548135 | Protein-protein interaction between the transcriptional repressor E4BP4 and the TBP-binding protein Dr1 |
| Q53291051 | Quantitative assessment of MLAA-34 expression in diagnosis and prognosis of acute monocytic leukemia |
| Q37426489 | RNA binding by the Wilms tumor suppressor zinc finger proteins. |
| Q34138129 | Recessive oncogenes: current status |
| Q42795981 | Reciprocal modulation between Sp1 and Egr-1 |
| Q24671965 | Regulated recruitment of HP1 to a euchromatic gene induces mitotically heritable, epigenetic gene silencing: a mammalian cell culture model of gene variegation |
| Q44226104 | Regulating the neoplastic phenotype using engineered transcriptional repressors |
| Q41077678 | Regulation of WT1 by phosphorylation: inhibition of DNA binding, alteration of transcriptional activity and cellular translocation |
| Q34820024 | Regulation of gene expression by WT1 in development and tumorigenesis |
| Q54372832 | Regulation of insulin-like growth factor I receptor gene expression by the Wilms' tumor suppressor WT1. |
| Q34592669 | Regulation of ornithine decarboxylase gene expression by the Wilms' tumor suppressor WT1. |
| Q40912238 | Regulation of the Wilms' tumour suppressor protein transcriptional activation domain. |
| Q37350292 | Regulation of transforming growth factor-beta 1 expression by the hepatitis B virus (HBV) X transactivator. Role in HBV pathogenesis |
| Q40204188 | Regulation of vascular endothelial growth factor, VEGF, gene promoter by the tumor suppressor, WT1. |
| Q27938018 | Repression by SSN6-TUP1 is directed by MIG1, a repressor/activator protein |
| Q38290555 | Repression of the c-myb gene by WT1 protein in T and B cell lines |
| Q36246379 | Role for Egr1 in the Transcriptional Program Associated with Neuronal Differentiation of PC12 Cells |
| Q36555870 | Role of EGR-1 in thapsigargin-inducible apoptosis in the melanoma cell line A375-C6. |
| Q38342103 | Role of Egr-1 Gene Expression in B Cell Receptor-induced Apoptosis in an Immature B Cell Lymphoma |
| Q42017225 | Role of the C-terminal domains of rice (Oryza sativa L.) bZIP proteins RF2a and RF2b in regulating transcription |
| Q38298155 | Sequence and structural requirements for high-affinity DNA binding by the WT1 gene product |
| Q36843618 | Sp1 is a critical regulator of the Wilms' tumor-1 gene |
| Q40230658 | Stereochemical basis of DNA recognition by Zn fingers |
| Q41844735 | Structural analysis of the human insulin-like growth factor-II P3 promoter |
| Q41590877 | The EGFR Gene Family in Embryonic Cell Activities |
| Q35870737 | The IE2 regulatory protein of human cytomegalovirus induces expression of the human transforming growth factor beta1 gene through an Egr-1 binding site |
| Q41175804 | The IGF-I receptor gene promoter is a molecular target for the Ewing's sarcoma-Wilms' tumor 1 fusion protein |
| Q73824829 | The Krüppel-associated box (KRAB)-zinc finger protein Kid-1 and the Wilms' tumor protein WT1, two transcriptional repressor proteins, bind to heteroduplex DNA |
| Q28592984 | The LIM-only coactivator FHL2 modulates WT1 transcriptional activity during gonadal differentiation |
| Q40017152 | The Transcriptional Repressor Even-skipped Interacts Directly with TATA-Binding Protein |
| Q41098050 | The WT1 Protein Is a Negative Regulator of the Normalbcl-2 Allele in t(14;18) Lymphomas |
| Q41302327 | The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis |
| Q42800235 | The Wilms tumor protein is persistently associated with the nuclear matrix throughout the cell cycle |
| Q57942684 | The Wilms tumor suppressor gene WT1 induces G1 arrest and apoptosis in myeloblastic leukemia M1 cells |
| Q38317044 | The Wilms tumour gene WT1 is expressed in murine mesoderm-derived tissues and mutated in a human mesothelioma |
| Q41729420 | The Wilms' Tumor 1 Gene: Oncogene or Tumor Suppressor Gene? |
| Q31492470 | The Wilms' tumor gene product (WT1) modulates the response to 1,25-dihydroxyvitamin D3 by induction of the vitamin D receptor |
| Q35889126 | The Wilms' tumour suppressor protein WT1 acts as a key transcriptional repressor of the human thromboxane A2 receptor gene in megakaryocytes |
| Q40620494 | The Wilms’ tumour suppressor protein, WT1, undergoes CRM1‐independent nucleocytoplasmic shuttling |
| Q24324714 | The ZNF35 human zinc finger gene encodes a sequence-specific DNA-binding protein |
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| Q40817158 | The human sex-determining gene SRY is a direct target of WT1. |
| Q36734704 | The immediate-early gene Egr-1 regulates the activity of the thymidine kinase promoter at the G0-to-G1 transition of the cell cycle. |
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| Q36028194 | Towards an understanding of Wilms' tumour. |
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