Regulating the neoplastic phenotype using engineered transcriptional repressors

scientific article

Regulating the neoplastic phenotype using engineered transcriptional repressors is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0304-3835(00)00649-2
P8608Fatcat IDrelease_aqnironixrgk7h32cm575bx3bu
P698PubMed publication ID11164187

P2093author name stringF J Rauscher
K Ayyanathan
W J Fredericks
P2860cites workKAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Krüppel-associated box-zinc finger proteins in heterochromatin-mediated gene silencing.Q22010040
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An engineered PAX3-KRAB transcriptional repressor inhibits the malignant phenotype of alveolar rhabdomyosarcoma cells harboring the endogenous PAX3-FKHR oncogeneQ33964561
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The Gfi-1 proto-oncoprotein contains a novel transcriptional repressor domain, SNAG, and inhibits G1 arrest induced by interleukin-2 withdrawalQ40020247
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Exogenous cdk4 overcomes reduced cdk4 RNA and inhibition of G1 progression in hematopoietic cells expressing a dominant-negative CBF - a model for overcoming inhibition of proliferation by CBF oncoproteinsQ40874612
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A fusion protein of the estrogen receptor (ER) and nuclear receptor corepressor (NCoR) strongly inhibits estrogen-dependent responses in breast cancer cellsQ40912005
Transiently transfected and stably integrated HIV-1 LTR responds differentially to the silencing activity of the Krüppel-associated box (KRAB) transcriptional repressor domainQ40935372
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Retinoblastoma protein tethered to promoter DNA represses TBP-mediated transcriptionQ41023470
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Active repression of transcription by the engrailed homeodomain proteinQ41080980
A dominant interfering Myb mutant causes apoptosis in T cellsQ41153561
Active repression mechanisms of eukaryotic transcription repressorsQ41223932
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Transcriptional repression mediated by the WT1 Wilms tumor gene productQ41661461
Estrogen receptor-KRAB chimeras are potent ligand-dependent repressors of estrogen-regulated gene expressionQ42487378
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Tissue-selective expression of dominant-negative proteins for the regulation of vascular smooth muscle cell proliferationQ45861589
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Dominant interfering alleles define a role for c-Myb in T-cell development.Q52217579
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Negative regulation of the forkhead transcription factor FKHR by Akt.Q52535267
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P407language of work or nameEnglishQ1860
P304page(s)S23-S32
P577publication date2001-01-01
P1433published inCancer LettersQ326372
P1476titleRegulating the neoplastic phenotype using engineered transcriptional repressors
P478volume162 Suppl

Reverse relations

cites work (P2860)
Q28305509Cell-type-specific regulation of distinct sets of gene targets by Pax3 and Pax3/FKHR
Q35847829Childhood rhabdomyosarcoma: recent advances and prospective views
Q34456861Chromosomal translocations in sarcomas: prospects for therapy
Q35057457Ewing's sarcoma: diagnostic, prognostic, and therapeutic implications of molecular abnormalities
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Q37180948Molecular approaches to sarcoma therapy
Q36250783Molecular profiling of childhood cancer: Biomarkers and novel therapies
Q34990652New insights in the transcriptional activity and coregulator molecules in the arterial wall

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