G1 phase arrest induced by Wilms tumor protein WT1 is abrogated by cyclin/CDK complexes

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G1 phase arrest induced by Wilms tumor protein WT1 is abrogated by cyclin/CDK complexes is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode1995PNAS...92.4517K
P356DOI10.1073/PNAS.92.10.4517
P932PMC publication ID41975
P698PubMed publication ID7753836
P5875ResearchGate publication ID15445028

P2093author name stringAkiyama T
Toyoshima K
Moriyama M
Kudoh T
Ishidate T
P2860cites workWT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia.Q38302906
The Wilms tumour gene WT1 is expressed in murine mesoderm-derived tissues and mutated in a human mesotheliomaQ38317044
Binding of the Wilms' tumor locus zinc finger protein to the EGR-1 consensus sequenceQ38338176
WT1-mediated growth suppression of Wilms tumor cells expressing a WT1 splicing variant.Q41508164
Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit.Q41508377
Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndromeQ41660674
Transcriptional repression mediated by the WT1 Wilms tumor gene productQ41661461
Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screenQ48084448
Expression of the Wilms' tumor gene (WT1) in human leukemiasQ53490672
Modulation of DNA binding specificity by alternative splicing of the Wilms tumor wt1 gene transcriptQ59662123
Repression of the insulin-like growth factor II gene by the Wilms tumor suppressor WT1Q67493857
Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signalsQ24314293
p15INK4B is a potential effector of TGF-beta-induced cell cycle arrestQ24319021
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinasesQ24319848
Cloning of a human gene, PIG-F, a component of glycosylphosphatidylinositol anchor biosynthesis, by a novel expression cloning strategyQ24323432
Human platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1Q24337538
Zinc finger point mutations within the WT1 gene in Wilms tumor patientsQ24561664
Rapid and efficient site-specific mutagenesis without phenotypic selectionQ27860608
WAF1, a potential mediator of p53 tumor suppressionQ27861121
Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locusQ28236741
Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumpingQ28236877
A novel cyclin associates with MO15/CDK7 to form the CDK-activating kinaseQ28247022
A cyclin associated with the CDK-activating kinase MO15Q28247696
p21 is a universal inhibitor of cyclin kinasesQ28257305
p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21Q28505037
WT-1 is required for early kidney developmentQ28512266
D-type cyclin-dependent kinase activity in mammalian cellsQ29614966
G1 phase progression: cycling on cueQ29615162
Cyclins and cancer. II: Cyclin D and CDK inhibitors come of ageQ29618409
An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumorQ34189532
The candidate Wilms' tumour gene is involved in genitourinary developmentQ34189819
Activation of cyclin-dependent kinase 4 (cdk4) by mouse MO15-associated kinaseQ36669326
Phosphorylation of the retinoblastoma protein by cdk2Q37169903
Alternative splicing and genomic structure of the Wilms tumor gene WT1Q37611742
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectnephroblastomaQ756289
P304page(s)4517-4521
P577publication date1995-05-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleG1 phase arrest induced by Wilms tumor protein WT1 is abrogated by cyclin/CDK complexes
P478volume92

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cites work (P2860)
Q42830606A functional interaction with CBP contributes to transcriptional activation by the Wilms tumor suppressor WT1.
Q24324095A novel repressor, par-4, modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1
Q52974188Analysis of Wilms tumor gene (WT1) expression in acute leukemia patients with special reference to the differential diagnosis between eosinophilic leukemia and idiopathic hypereosinophilic syndromes.
Q30530827Asbestos and mesothelioma: genetic lessons from a tragedy
Q24303633BASP1 is a transcriptional cosuppressor for the Wilms' tumor suppressor protein WT1
Q42049050Cell cycle regulation and differentiation in the human podocyte lineage
Q44092524Changes in WT1 splicing are associated with a specific gene expression profile in Wilms' tumour
Q24309269Ciao 1 is a novel WD40 protein that interacts with the tumor suppressor protein WT1
Q42817131Cyclin E is a target of WT1 transcriptional repression
Q40716988Downregulation of Wilms' tumor 1 protein inhibits breast cancer proliferation
Q36569185Expression and function of the leucine zipper protein Par-4 in apoptosis
Q34551202Expression of inhibin-alpha is regulated synergistically by Wilms' tumor gene 1 (Wt1) and steroidogenic factor-1 (Sf1) in sertoli cells
Q34438119Genetic predisposition to cancer and familial cancer syndromes
Q22003911Induction of Rb-associated protein (RbAp46) by Wilms' tumor suppressor WT1 mediates growth inhibition
Q24308507Inhibition of cellular proliferation by the Wilms tumor suppressor WT1 requires association with the inducible chaperone Hsp70
Q40937124Internal translation initiation generates novel WT1 protein isoforms with distinct biological properties
Q33723073Lipoplexes and tumours. A review
Q34378971MCC, a cytoplasmic protein that blocks cell cycle progression from the G0/G1 to S phase
Q24322684Molecular cloning of the cDNA and chromosome localization of the gene for human ubiquitin-conjugating enzyme 9
Q74615935Novel growth factor supporting survival of murine primordial germ cells: evidence from conditioned medium of ter fetal gonadal somatic cells
Q40728596Pathological splice mutations outside the invariant AG/GT splice sites of BRCA1 exon 5 increase alternative transcript levels in the 5' end of the BRCA1 gene
Q41157249Suppression of fibroblast cell growth by overexpression of LIM-kinase 1.
Q42800235The Wilms tumor protein is persistently associated with the nuclear matrix throughout the cell cycle
Q34077533The Wilms tumor suppressor WT1 directs stage-specific quiescence and differentiation of human hematopoietic progenitor cells
Q57942684The Wilms tumor suppressor gene WT1 induces G1 arrest and apoptosis in myeloblastic leukemia M1 cells
Q41663756The Wilms tumour gene WT1 in leukaemia
Q24310213The tumour suppressor gene product APC blocks cell cycle progression from G0/G1 to S phase
Q41625163Tumor suppressor genes and human cancer
Q33786522Tumor suppressor p53 can participate in transcriptional induction of the GADD45 promoter in the absence of direct DNA binding
Q38325277Tumor-associated WT1 missense mutants indicate that transcriptional activation by WT1 is critical for growth control
Q34293053Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors. Mesothelioma
Q34820008Wilms tumor gene (WT1) expression as a panleukemic marker
Q40114088Wilms' tumor protein 1: an early target of progestin regulation in T-47D breast cancer cells that modulates proliferation and differentiation
Q36234726Wilms' tumour: connecting tumorigenesis and organ development in the kidney

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