Gene targeting in kidney development

scientific article published on November 1996

Gene targeting in kidney development is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1002/(SICI)1096-911X(199611)27:5<445::AID-MPO10>3.0.CO;2-9
P698PubMed publication ID8827072

P2093author name stringKreidberg JA
P2860cites workRequirement for Lim1 in head-organizer functionQ24312737
Human platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1Q24337538
Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locusQ28236741
A syndrome of pseudohermaphroditism, Wilms' tumor, hypertension, and degenerative renal diseaseQ28239519
Essential role of stromal mesenchyme in kidney morphogenesis revealed by targeted disruption of Winged Helix transcription factor BF-2Q28504535
A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eyeQ28508005
Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4Q28508296
WT-1 is required for early kidney developmentQ28512266
Deficient outgrowth of the ureteric bud underlies the renal agenesis phenotype in mice manifesting the limb deformity (ld) mutationQ28513203
Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hairQ28586758
Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopeniaQ28591736
An inherited limb deformity created by insertional mutagenesis in a transgenic mouseQ28592717
Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor RetQ29620364
Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalitiesQ33491173
Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice.Q33491174
Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vectorQ34189858
Expression patterns of the murine LIM class homeobox gene lim1 in the developing brain and excretory system.Q34322302
Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice.Q34341740
Formins: phosphoprotein isoforms encoded by the mouse limb deformity locusQ36363617
Pax-2 is a DNA-binding protein expressed in embryonic kidney and Wilms tumorQ36826291
Nephrogenic rests, nephroblastomatosis, and the pathogenesis of Wilms' tumorQ37874427
Binding of the Wilms' tumor locus zinc finger protein to the EGR-1 consensus sequenceQ38338176
The new mouse genetics: altering the genome by gene targetingQ38646807
Renal Anemia in Polycystic Kidney Disease MouseQ39101310
The genetics of Wilms' tumor--a case of disrupted developmentQ40614052
Polycystic kidney disease: primary extracellular matrix abnormality or defective cellular differentiation?Q40876083
N-myc proto-oncogene expression during organogenesis in the developing mouse as revealed by in situ hybridizationQ41558787
Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndromeQ41660674
Transcriptional repression mediated by the WT1 Wilms tumor gene productQ41661461
Contrasting expression patterns of three members of the myc family of protooncogenes in the developing and adult mouse kidneyQ42004438
Are morphogenetic tissue interactions mediated by transmissible signal substances or through cell contacts?Q44340477
Nephrogenic Rests in Wilms Tumor Patients with the Drash SyndromeQ46664411
WT1 mutations contribute to abnormal genital system development and hereditary Wilms' tumourQ48206248
Embryonic lethality in mice homozygous for a targeted disruption of the N-myc geneQ48400477
Deregulation of Pax-2 expression in transgenic mice generates severe kidney abnormalities.Q52226238
Germline intronic and exonic mutations in the Wilms' tumour gene (WT1) affecting urogenital developmentQ52231802
Mice with a null mutation of the TGF alpha gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation.Q52517769
TGF alpha deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice.Q52517773
Parental imprinting of the mouse insulin-like growth factor II gene.Q55052428
The Mouse Congenital Polycystic Kidney (cpk) Locus Maps within 1.3 cM of the Chromosome 12 Marker D12Nyu2Q57000868
Evidence that WT1 mutations in Denys — Drash syndrome patients may act in a dominant-negative fashionQ59662118
Repression of the insulin-like growth factor II gene by the Wilms tumor suppressor WT1Q67493857
Loss of N-myc function results in embryonic lethality and failure of the epithelial component of the embryo to developQ67599796
Characterization of the Upper Urinary Tract Anatomy in the Danforth Spontaneous Murine MutationQ68227549
A null c-myc mutation causes lethality before 10.5 days of gestation in homozygotes and reduced fertility in heterozygous female miceQ70624275
Renal and biliary abnormalities in a new murine model of autosomal recessive polycystic kidney diseaseQ70667759
Juvenile cystic kidneys (jck): a new mouse mutation which causes polycystic kidneysQ70758568
BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterningQ71817916
Denys-Drash syndrome: relating a clinical disorder to genetic alterations in the tumor suppressor gene WT1Q72577728
Inactivation of WT1 in nephrogenic rests, genetic precursors to Wilms' tumourQ72751031
Inductive epitheliomesenchymal interaction in cultured organ rudiments of the mouseQ73225452
P433issue5
P921main subjectgene targetingQ211083
P304page(s)445-452
P577publication date1996-11-01
P1433published inPediatric Blood & CancerQ15754342
P1476titleGene targeting in kidney development
P478volume27

Reverse relations

cites work (P2860)
Q35124266Deficiency of the planar cell polarity protein Vangl2 in podocytes affects glomerular morphogenesis and increases susceptibility to injury.
Q33744636Embryonic renal epithelia: induction, nephrogenesis, and cell differentiation
Q28365766Failure of ureteric bud invasion: a new model of renal agenesis in mice
Q24322628Loss-of-function mutations in the LIM-homeodomain gene, LMX1B, in nail-patella syndrome
Q34031394Principles of Wilms' tumor biology
Q77378783Renal dysplasia: the risks and consequences of leaving dysplastic tissue in situ
Q33379641Simulations of a specific inhibitor of the dishevelled PDZ domain
Q33888488Soluble dominant-negative receptor uncovers essential roles for fibroblast growth factors in multi-organ induction and patterning
Q40529835Transcriptional activation of c-myc proto-oncogene by WT1 protein
Q63199214Wilms Tumor Gene Immunoreactivity in Primary Serous Carcinomas of the Fallopian Tube, Ovary, Endometrium, and Peritoneum
Q33727614Wilms' tumor and related abnormalities in the fetus and newborn
Q39979771Wilms' tumor protein (-KTS) modulates renin gene transcription.

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