EGR-mediated control of STIM expression and function

scientific article published on 06 December 2018

EGR-mediated control of STIM expression and function is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CECA.2018.12.003
P932PMC publication ID6467086
P698PubMed publication ID30553973

P50authorScott GrossQ90558488
Jonathan SoboloffQ37381829
P2093author name stringRobert Hooper
Christina K Go
P2860cites workOrai1 and STIM reconstitute store-operated calcium channel functionQ24293232
Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1Q24294877
STIM2 is a feedback regulator that stabilizes basal cytosolic and endoplasmic reticulum Ca2+ levelsQ24304975
Co-operative interactions between NFAT (nuclear factor of activated T cells) c1 and the zinc finger transcription factors Sp1/Sp3 and Egr-1 regulate MT1-MMP (membrane type 1 matrix metalloproteinase) transcription by glomerular mesangial cellsQ24311377
PTEN regulation by Akt-EGR1-ARF-PTEN axisQ24321834
EGR3, a novel member of the Egr family of genes encoding immediate-early transcription factorsQ24322920
NF-kappaB/Egr-1/Gadd45 are sequentially activated upon UVB irradiation to mediate epidermal cell deathQ24336481
Amplification of CRAC current by STIM1 and CRACM1 (Orai1)Q24338326
Serum response factor binding sites differ in three human cell typesQ24338662
Genome-wide RNAi screen of Ca(2+) influx identifies genes that regulate Ca(2+) release-activated Ca(2+) channel activityQ24548526
A tale of three fingers: the family of mammalian Sp/XKLF transcription factorsQ24548846
DNA binding site of the growth factor-inducible protein Zif268Q24603450
STIM proteins: dynamic calcium signal transducersQ24633618
Pathways of Egr-1-mediated gene transcription in vascular biologyQ24671655
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Energy metabolism in the liverQ26996783
Tumor infiltrating lymphocytes in ovarian cancerQ27021878
Disease Progression Mediated by Egr-1 Associated Signaling in Response to Oxidative StressQ27022982
RBFOX3/NeuN is Required for Hippocampal Circuit Balance and FunctionQ27304815
Structural and mechanistic insights into STIM1-mediated initiation of store-operated calcium entryQ27652503
The Role of the Ubiquitously Expressed Transcription Factor Sp1 in Tissue-specific Transcriptional Regulation and in DiseaseQ28076855
Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequenceQ28117086
Amplification and overexpression of CACNA1E correlates with relapse in favorable histology Wilms' tumorsQ28280617
Stromal interaction molecule (STIM) 1 and STIM2 calcium sensing regions exhibit distinct unfolding and oligomerization kineticsQ28301371
Mechanism of doxorubicin-induced inhibition of sarcoplasmic reticulum Ca(2+)-ATPase gene transcriptionQ28378463
Coordinate Expression and Distinct DNA-Binding Characteristics of the Four EGR-Zinc Finger Proteins in Jurkat T lymphocytesQ38340689
Sp1 and Sp3 transcription factors are required for trans-activation of the human SERCA2 promoter in cardiomyocytesQ38348133
Early growth response protein-1 (Egr-1) is preferentially expressed in T helper type 2 (Th2) cells and is involved in acute transcription of the Th2 cytokine interleukin-4.Q38348879
Casein kinase II associates with Egr-1 and acts as a negative modulator of its DNA binding and transcription activities in NIH 3T3 cellsQ38356832
Gene expression profiling of favorable histology Wilms tumors and its correlation with clinical features.Q38360869
The hematopoietic tumor suppressor interferon regulatory factor 8 (IRF8) is upregulated by the antimetabolite cytarabine in leukemic cells involving the zinc finger protein ZNF224, acting as a cofactor of the Wilms' tumor gene 1 (WT1) protein.Q38819798
Alternative splicing of Wilms tumor suppressor 1 (Wt1) exon 4 results in protein isoforms with different functionsQ46867713
Transcription factors early growth response gene (Egr) 2 and 3 control inflammatory responses of tolerant T cells.Q48285288
Immediate early gene induction after neonatal hypoxia-ischemiaQ48299914
Early growth response 2 (Egr-2) expression is triggered by NF-κB activationQ48393413
Egr-1 mediated cardiac miR-99 family expression diverges physiological hypertrophy from pathological hypertrophy.Q51418960
Base sequence discrimination by zinc-finger DNA-binding domainsQ52447039
Wilms' tumor 1-KTS isoforms induce p53-independent apoptosis that can be partially rescued by expression of the epidermal growth factor receptor or the insulin receptor.Q53444758
Store-Operated Calcium ChannelsQ54046109
New prognostic markers revealed by evaluation of genes correlated with clinical parameters in Wilms tumors.Q54547476
Down-regulation of Orai3 arrests cell-cycle progression and induces apoptosis in breast cancer cells but not in normal breast epithelial cells.Q54658275
Overexpression of early growth response-1 as a metastasis-regulatory factor in gastric cancer.Q54793036
The transcriptional repressor Nab1 is a specific regulator of pathological cardiac hypertrophyQ60992399
Abnormal intracellular calcium handling in myocardium from patients with end-stage heart failureQ69122833
Decreased expression of cardiac sarcoplasmic reticulum Ca(2+)-pump ATPase in congestive heart failure due to myocardial infarctionQ71918853
Decoding of cytosolic calcium oscillations in the mitochondriaQ71955698
Relation between myocardial function and expression of sarcoplasmic reticulum Ca(2+)-ATPase in failing and nonfailing human myocardiumQ72133115
Effects of inhibition of sarcoplasmic reticulum calcium uptake on contraction in myocytes isolated from failing human ventricleQ73129871
Native and oxidized low density lipoprotein induction of tissue factor gene expression in smooth muscle cells is mediated by both Egr-1 and Sp1Q73157333
Downregulation of sarcoplasmic reticulum Ca(2+)-ATPase during progression of left ventricular hypertrophyQ73399779
Early growth response gene 1 (EGR1) is deleted in estrogen receptor-negative human breast carcinomaQ81927616
Hypoxia stabilizes microtubule networks and decreases tumor cell chemosensitivity to anticancer drugs through Egr-1Q82966248
Regulatory polymorphisms in EGR2 are associated with susceptibility to systemic lupus erythematosusQ83088689
ORAI1 Ca(2+) channels control endothelin-1-induced mitogenesis and melanogenesis in primary human melanocytesQ83409008
Single-Base Resolution Analysis of 5-Formyl and 5-Carboxyl Cytosine Reveals Promoter DNA Methylation DynamicsQ86688630
Role of early growth response 1 in liver metabolism and liver cancerQ88241475
Effect of intracoronary administration of AAV1/SERCA2a on ventricular remodelling in patients with advanced systolic heart failure: results from the AGENT-HF randomized phase 2 trialQ38844989
Distinct Orai-coupling domains in STIM1 and STIM2 define the Orai-activating siteQ38885774
The Role of WT1 in Embryonic Development and Normal Organ HomeostasisQ38897318
Calcium microdomains at the immunological synapse: how ORAI channels, mitochondria and calcium pumps generate local calcium signals for efficient T-cell activation.Q38967624
Store-Operated Ca2+ Entry Controls Induction of Lipolysis and the Transcriptional Reprogramming to Lipid MetabolismQ38993107
EGR1-dependent PTEN upregulation by 2-benzoyloxycinnamaldehyde attenuates cell invasion and EMT in colon cancerQ39007571
STIM-1 and ORAI-1 channel mediate angiotensin-II-induced expression of Egr-1 in vascular smooth muscle cells.Q39010799
Cancer Statistics, 2017.Q39038674
Calcium-NFAT transcriptional signalling in T cell activation and T cell exhaustionQ39116081
Phosphoglycerate kinase 1 as a promoter of metastasis in colon cancerQ39144874
The master role of microphthalmia-associated transcription factor in melanocyte and melanoma biologyQ39163758
Epidermal growth factor induces human oviductal epithelial cell invasion by down-regulating E-cadherin expressionQ39351888
STIM1 is required for attenuation of PMCA-mediated Ca2+ clearance during T-cell activationQ39412080
Vascular endothelial growth factor activates nuclear factor of activated T cells in human endothelial cells: a role for tissue factor gene expression.Q39444857
Telomere length and associations with somatic mutations and clinical outcomes in acute myeloid leukemiaQ39446192
The human zinc finger protein EGR-4 acts as autoregulatory transcriptional repressorQ39632910
Orai1 and STIM1 are critical for breast tumor cell migration and metastasisQ39888627
Elk-1, CREB, and MKP-1 regulate Egr-1 expression in gonadotropin-releasing hormone stimulated gonadotrophsQ39936346
Early growth response-1 mediates downregulation of telomerase in cervical cancerQ39984972
Wilms tumor suppressor 1 (WT1) and early growth response 1 (EGR1) are regulators of STIM1 expressionQ40075439
CRACM1, CRACM2, and CRACM3 are store-operated Ca2+ channels with distinct functional properties.Q40144074
Egr-1 promotes hypoxia-induced autophagy to enhance chemo-resistance of hepatocellular carcinoma cellsQ40167291
Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiationQ40208549
Egr2 and 3 Inhibit T-bet-Mediated IFN-γ Production in T Cells.Q40222259
Early growth response proteins EGR-4 and EGR-3 interact with immune inflammatory mediators NF-kappaB p50 and p65.Q40398205
Promoter CpG hypomethylation and transcription factor EGR1 hyperactivate heparanase expression in bladder cancerQ40399494
Cleavage of beta-catenin by calpain in prostate and mammary tumor cellsQ40502750
The role of calpain in the proteolytic cleavage of E-cadherin in prostate and mammary epithelial cellsQ40694935
Modulation of early growth response (EGR) transcription factor-dependent gene expression by using recombinant adenovirus.Q40838368
Egr-1 inhibits apoptosis during the UV response: correlation of cell survival with Egr-1 phosphorylationQ40961191
The role of early growth response gene 1 (egr-1) in regulation of the immune response.Q41084702
Inhibition of dipeptidyl peptidase-4 ameliorates cardiac ischemia and systolic dysfunction by up-regulating the FGF-2/EGR-1 pathway.Q41237048
Transcriptional repression mediated by the WT1 Wilms tumor gene productQ41661461
Physical activity and survival among men diagnosed with prostate cancerQ41665208
Neurturin evokes MAPK-dependent upregulation of Egr4 and KCC2 in developing neuronsQ41876060
5-Carboxylcytosine levels are elevated in human breast cancers and gliomasQ41984930
A slow-cycling subpopulation of melanoma cells with highly invasive properties.Q41996634
Transcriptional Regulation of EGR1 by EGF and the ERK Signaling Pathway in Prostate Cancer CellsQ42164214
Novel STIM1-dependent control of Ca2+ clearance regulates NFAT activity during T-cell activationQ42705474
Detection and characterization of cellular EGR-1 binding to its recognition siteQ42807256
Highly efficient and specific modulation of cardiac calcium homeostasis by adenovector-derived short hairpin RNA targeting phospholambanQ45863016
Wilms' tumor 1 gene expression in hepatocellular carcinoma promotes cell dedifferentiation and resistance to chemotherapy.Q45882973
Moderate heart dysfunction in mice with inducible cardiomyocyte-specific excision of the Serca2 geneQ46071152
Regulation and rate limiting mechanisms of Ca2+ ATPase (SERCA2) expression in cardiac myocytesQ46454345
Remote ischemic preconditioning attenuates EGR-1 expression following myocardial ischemia reperfusion injury through activation of the JAK-STAT pathway.Q46454447
PKC-independent signal transduction pathways increase SERCA2 expression in adult rat cardiomyocytesQ46763219
A functional polymorphism of the Galphaq (GNAQ) gene is associated with accelerated mortality in African-American heart failureQ46790615
SUMO1-dependent modulation of SERCA2a in heart failureQ28508610
Synaptic activity controls localization and function of CtBP1 via binding to Bassoon and PiccoloQ28512052
Transcriptional activation of egr-1 by granulocyte-macrophage colony-stimulating factor but not interleukin 3 requires phosphorylation of cAMP response element-binding protein (CREB) on serine 133Q28611436
The versatility and universality of calcium signallingQ29547402
Dynamic movement of the calcium sensor STIM1 and the calcium channel Orai1 in activated T-cells: puncta and distal capsQ30482508
Orai1 and STIM1 move to the immunological synapse and are up-regulated during T cell activation.Q30483548
Induction of epithelial-mesenchymal transition (EMT) in breast cancer cells is calcium signal dependentQ30571243
Regulation of Egr-1 by association with the proteasome component C8.Q30863543
Coordinated sumoylation and ubiquitination modulate EGF induced EGR1 expression and stabilityQ31037167
Thrombin induces Egr-1 expression in fibroblasts involving elevation of the intracellular Ca2+ concentration, phosphorylation of ERK and activation of ternary complex factorQ33443507
MicroRNA-150 modulates intracellular Ca 2+ levels in naïve CD8+ T cells by targeting TMEM20.Q33752767
Functional compensation by Egr4 in Egr1-dependent luteinizing hormone regulation and Leydig cell steroidogenesisQ33964658
SERCA pump isoforms: their role in calcium transport and diseaseQ34002326
Egr-1 regulates the transcription of NGX6 gene through a Sp1/Egr-1 overlapping site in the promoterQ34052476
Calcium, calcineurin, and the control of transcriptionQ34092392
Cooperative signaling via transcription factors NF-κB and AP1/c-Fos mediates endothelial cell STIM1 expression and hyperpermeability in response to endotoxinQ34107201
Genomic organization, chromosomal localization and promoter function of the human zinc-finger gene pAT133.Q34365922
MAML1 acts cooperatively with EGR1 to activate EGR1-regulated promoters: implications for nephrogenesis and the development of renal cancerQ34430565
Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.Q34438345
TGF-β3-expressing CD4+CD25(-)LAG3+ regulatory T cells control humoral immune responsesQ34463612
Egr-1 induces the expression of its corepressor nab2 by activation of the nab2 promoter thereby establishing a negative feedback loopQ34464142
Early growth response-1 in cardiovascular pathobiologyQ34491148
NAB2 represses transcription by interacting with the CHD4 subunit of the nucleosome remodeling and deacetylase (NuRD) complexQ34507079
αβ versus γδ fate choice: counting the T-cell lineages at the branch point.Q34540532
Orai1 contributes to the establishment of an apoptosis-resistant phenotype in prostate cancer cells.Q34545497
Calcium inhibition and calcium potentiation of Orai1, Orai2, and Orai3 calcium release-activated calcium channelsQ34621761
The Calcium/Calmodulin-dependent Protein Phosphatase Calcineurin Is the Major Elk-1 PhosphataseQ34743578
Convergence of integrins and EGF receptor signaling via PI3K/Akt/FoxO pathway in early gene Egr-1 expressionQ34849155
Prognostic significance of specific anti-WT1 IgG antibody level in plasma in patients with ovarian carcinomaQ35000449
Wilms' tumor protein induces an epithelial-mesenchymal hybrid differentiation state in clear cell renal cell carcinomaQ35206917
Calcium store sensor stromal-interaction molecule 1-dependent signaling plays an important role in cervical cancer growth, migration, and angiogenesisQ35216980
Calcium oscillations in T-cells: mechanisms and consequences for gene expressionQ35541336
EGR4 displays both a cell- and intracellular-specific localization pattern in the developing murine testisQ35556850
WT1/EGR1-mediated control of STIM1 expression and function in cancer cellsQ35575649
Chemical approaches to understanding O-GlcNAc glycosylation in the brainQ35648339
Transcription factor NF-κB regulates expression of pore-forming Ca2+ channel unit, Orai1, and its activator, STIM1, to control Ca2+ entry and affect cellular functionsQ35710065
Structural impact of complete CpG methylation within target DNA on specific complex formation of the inducible transcription factor Egr-1.Q35828415
Downregulation of ATG14 by EGR1-MIR152 sensitizes ovarian cancer cells to cisplatin-induced apoptosis by inhibiting cyto-protective autophagyQ35852880
Novel Protein Kinase C-Mediated Control of Orai1 Function in Invasive MelanomaQ35868399
STIM1 accelerates cell senescence in a remodeled microenvironment but enhances the epithelial-to-mesenchymal transition in prostate cancerQ35932914
The STIM1-ORAI1 microdomainQ36042498
Wilms' tumour: connecting tumorigenesis and organ development in the kidneyQ36234726
The transcription factors Egr2 and Egr3 are essential for the control of inflammation and antigen-induced proliferation of B and T cells.Q36335917
Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: roles of the nuclear factor of activated T cells and cyclooxygenase 2Q36369190
Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosisQ36399732
CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidityQ36401360
Opposing regulation of T cell function by Egr-1/NAB2 and Egr-2/Egr-3.Q36685758
A tumor suppressor and oncogene: the WT1 story.Q36760031
Promoter methylation of Egr-1 site contributes to fetal hypoxia-mediated PKCε gene repression in the developing heartQ36837938
Orai1 Expression Is Closely Related with Favorable Prognostic Factors in Clear Cell Renal Cell CarcinomaQ36859838
T Cell Receptor-induced Nuclear Factor κB (NF-κB) Signaling and Transcriptional Activation Are Regulated by STIM1- and Orai1-mediated Calcium EntryQ36884601
Mitogen-activated protein kinase-activated protein kinases 2 and 3 regulate SERCA2a expression and fiber type composition to modulate skeletal muscle and cardiomyocyte functionQ36978298
Interplay between EGR1 and SP1 is critical for 13-cis retinoic acid-mediated transcriptional repression of angiotensin type 1A receptor.Q37088322
The short N-terminal domains of STIM1 and STIM2 control the activation kinetics of Orai1 channelsQ37339236
The cellular context of T cell signalingQ37446125
Egr2 and Egr3 in regulatory T cells cooperatively control systemic autoimmunity through Ltbp3-mediated TGF-β3 productionQ37514840
Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation.Q37625844
Egr-1 regulates irradiation-induced autophagy through Atg4B to promote radioresistance in hepatocellular carcinoma cellsQ37627451
WT1 in disease: shifting the epithelial-mesenchymal balance.Q37940867
Hypoxia in atherosclerosis and inflammationQ38128669
The transcription factor Zif268/Egr1, brain plasticity, and memoryQ38183977
Expression, signaling and function of Egr transcription factors in pancreatic β-cells and insulin-responsive tissuesQ38196148
Inhibition of the RelA(p65) NF-kappaB subunit by Egr-1.Q38315535
The Wilms' tumor gene (WT1) regulates E-cadherin expression and migration of prostate cancer cellsQ38318725
Steroidogenic organ development and homeostasis: A WT1-centric viewQ38321804
Egr-1 negatively regulates expression of the sodium-calcium exchanger-1 in cardiomyocytes in vitro and in vivoQ38332624
P304page(s)58-67
P577publication date2018-12-06
P1433published inCell CalciumQ4340020
P1476titleEGR-mediated control of STIM expression and function
P478volume77

Reverse relations

Q92941380Very Low-Density Lipoproteins of Metabolic Syndrome Modulates STIM1, Suppresses Store-Operated Calcium Entry, and Deranges Myofilament Proteins in Atrial Myocytescites workP2860

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