| scholarly article | Q13442814 |
| P50 | author | Steve F. Abcouwer | Q37379185 |
| Patrice E. Fort | Q37834582 | ||
| Thomas W. Gardner | Q38330967 | ||
| P2093 | author name string | Makoto Nakamura | |
| Alistair J Barber | |||
| Chad E N Reiter | |||
| Mandy K Losiewicz | |||
| Ravi S J Singh | |||
| P2860 | cites work | Diabetes reduces autophosphorylation of retinal insulin receptor and increases protein-tyrosine phosphatase-1B activity | Q24317296 |
| The diaphanous-related formin DAAM1 collaborates with the Rho GTPases RhoA and Cdc42, CIP4 and Src in regulating cell morphogenesis and actin dynamics | Q24319184 | ||
| A novel missense mutation in SLC5A2 encoding SGLT2 underlies autosomal-recessive renal glucosuria and aminoaciduria | Q28299174 | ||
| The retinal proteome in experimental diabetic retinopathy: up-regulation of crystallins and reversal by systemic and periocular insulin | Q28388205 | ||
| Protein kinase C-delta mediates neuronal apoptosis in the retinas of diabetic rats via the Akt signaling pathway | Q28572961 | ||
| SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver | Q29547646 | ||
| Remodeling of retinal Fatty acids in an animal model of diabetes: a decrease in long-chain polyunsaturated fatty acids is associated with a decrease in fatty acid elongases Elovl2 and Elovl4. | Q33556542 | ||
| Hypoglycemia is the limiting factor in the management of diabetes | Q33683015 | ||
| Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats | Q33857313 | ||
| Chronic insulin treatment of diabetes does not fully normalize alterations in the retinal transcriptome | Q33901377 | ||
| Enhanced stimulation of Akt-3/protein kinase B-gamma in human aortic smooth muscle cells | Q33944142 | ||
| Transcriptional profiling of diabetic neuropathy in the BKS db/db mouse: a model of type 2 diabetes. | Q35063229 | ||
| Functions of insulin and insulin receptor signaling in retina: possible implications for diabetic retinopathy | Q35125732 | ||
| Diabetes and Insulin in Regulation of Brain Cholesterol Metabolism | Q35499561 | ||
| Insulin signaling in retinal neurons is regulated within cholesterol-enriched membrane microdomains. | Q35756442 | ||
| Phlorizin: a review | Q35995949 | ||
| Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulin | Q37384532 | ||
| Sodium-glucose co-transport inhibitors: progress and therapeutic potential in type 2 diabetes mellitus | Q37703184 | ||
| Vascular permeability in experimental diabetes is associated with reduced endothelial occludin content: vascular endothelial growth factor decreases occludin in retinal endothelial cells. Penn State Retina Research Group | Q39481123 | ||
| Role of hyperglycaemia in the pathogenesis of hypotension observed in type-1 diabetic rats | Q39948965 | ||
| Excessive hexosamines block the neuroprotective effect of insulin and induce apoptosis in retinal neurons | Q40780090 | ||
| Insulin rescues retinal neurons from apoptosis by a phosphatidylinositol 3-kinase/Akt-mediated mechanism that reduces the activation of caspase-3. | Q40793937 | ||
| Effect of chronic hyperglycemia on in vivo insulin secretion in partially pancreatectomized rats. | Q41015653 | ||
| Characterization of insulin signaling in rat retina in vivo and ex vivo | Q42442753 | ||
| Diabetes reduces basal retinal insulin receptor signaling: reversal with systemic and local insulin | Q42492673 | ||
| Effects of ischemic preconditioning and bevacizumab on apoptosis and vascular permeability following retinal ischemia-reperfusion injury | Q43017172 | ||
| The contribution of hyperglycaemia and hypoinsulinaemia to the insulin resistance of streptozotocin-diabetic rats | Q43996740 | ||
| Strain-dependent increases in retinal inflammatory proteins and photoreceptor FGF-2 expression in streptozotocin-induced diabetic rats | Q44079746 | ||
| Apoptotic death of photoreceptors in the streptozotocin-induced diabetic rat retina | Q44536369 | ||
| Increased O-glycosylation of insulin signaling proteins results in their impaired activation and enhanced susceptibility to apoptosis in pancreatic beta-cells | Q44827054 | ||
| Death of retinal neurons in streptozotocin-induced diabetic mice | Q45028039 | ||
| Expression of acute-phase response proteins in retinal Müller cells in diabetes | Q45205307 | ||
| Hyperglycemia does not increase basal hypothalamo-pituitary-adrenal activity in diabetes but it does impair the HPA response to insulin-induced hypoglycemia | Q46387468 | ||
| The Ins2Akita mouse as a model of early retinal complications in diabetes | Q46508398 | ||
| Peroxynitrite mediates retinal neurodegeneration by inhibiting nerve growth factor survival signaling in experimental and human diabetes | Q46745027 | ||
| Na(+) -glucose transporter-2 messenger ribonucleic acid expression in kidney of diabetic rats correlates with glycemic levels: involvement of hepatocyte nuclear factor-1alpha expression and activity. | Q46930511 | ||
| Nonobese, insulin-deficient Ins2Akita mice develop type 2 diabetes phenotypes including insulin resistance and cardiac remodeling | Q46970404 | ||
| Rescue and regeneration of injured peripheral nerve axons by intrathecal insulin | Q46985205 | ||
| Nerve growth factor: a mitogenic signal for retinal Müller glial cells | Q48103599 | ||
| Near nerve local insulin prevents conduction slowing in experimental diabetes | Q48655775 | ||
| In situ kinetics of glucose transport across the blood-retinal barrier in normal rats and rats with streptozocin-induced diabetes. | Q48890747 | ||
| Kinetics of Steady-state Currents and Charge Movements Associated with the Rat Na+/Glucose Cotransporter | Q49032465 | ||
| Flavonoids are scavengers of superoxide anions. | Q50897561 | ||
| Glial retinal Müller cells produce IL-1 activity and have a dual effect on autoimmune T helper lymphocytes. Antigen presentation manifested after removal of suppressive activity | Q57281217 | ||
| A multistep validation process of biomarkers for preclinical drug development | Q60471851 | ||
| Altered expression of retinal occludin and glial fibrillary acidic protein in experimental diabetes. The Penn State Retina Research Group | Q73006546 | ||
| Antioxidant action of novel derivatives of the apple-derived flavonoid phloridzin compared to oestrogen: relevance to potential cardioprotective action | Q73124646 | ||
| Proteomic analysis of human vitreous fluid by fluorescence-based difference gel electrophoresis (DIGE): a new strategy for identifying potential candidates in the pathogenesis of proliferative diabetic retinopathy | Q80020556 | ||
| P275 | copyright license | Creative Commons CC0 License | Q6938433 |
| P6216 | copyright status | copyrighted, dedicated to the public domain by copyright holder | Q88088423 |
| P433 | issue | 10 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | hyperglycemia | Q271993 |
| insulin resistance | Q1053470 | ||
| cell death | Q2383867 | ||
| preproinsulin | Q7240673 | ||
| P304 | page(s) | e26498 | |
| P577 | publication date | 2011-01-01 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | Differential roles of hyperglycemia and hypoinsulinemia in diabetes induced retinal cell death: evidence for retinal insulin resistance | |
| P478 | volume | 6 |
| Q40878074 | A mitochondrial therapeutic reverses visual decline in mouse models of diabetes |
| Q36846608 | Changes in gene expression associated with retinal degeneration in the rd3 mouse |
| Q36379507 | Clinical biomarkers and molecular basis for optimized treatment of diabetic retinopathy: current status and future prospects |
| Q47598234 | Deletion of the Akt/mTORC1 Repressor REDD1 Prevents Visual Dysfunction in a Rodent Model of Type 1 Diabetes. |
| Q34553087 | Diabetic Retinopathy-Update on Prevention Techniques, Present Therapies, and New Leads |
| Q38199730 | Diabetic retinopathy: loss of neuroretinal adaptation to the diabetic metabolic environment |
| Q42672190 | Diabetic retinopathy: research to clinical practice |
| Q39678862 | Does Retinal Neurodegeneration Seen in Diabetic Patients Begin in the Insulin Resistance Stage? |
| Q46500518 | Flavonoid Naringenin Attenuates Oxidative Stress, Apoptosis and Improves Neurotrophic Effects in the Diabetic Rat Retina |
| Q91987122 | HMGB1 inhibits insulin signalling through TLR4 and RAGE in human retinal endothelial cells |
| Q37014991 | Hyperglycemia mediates a shift from cap-dependent to cap-independent translation via a 4E-BP1-dependent mechanism |
| Q38656651 | Nanoparticle-Mediated Delivery of Neuroprotective Substances for the Treatment of Diabetic Retinopathy |
| Q37403350 | Neuroanatomical correlates of dysglycemia in young children with type 1 diabetes |
| Q90376643 | Neurodegeneration in diabetic retinopathy: does it really matter? |
| Q38112711 | Neurodegeneration in the pathogenesis of diabetic retinopathy: molecular mechanisms and therapeutic implications |
| Q26749178 | Neuroprotection as a Therapeutic Target for Diabetic Retinopathy |
| Q36066571 | Phosphatase control of 4E-BP1 phosphorylation state is central for glycolytic regulation of retinal protein synthesis |
| Q36765801 | Reduced insulin receptor signaling in retinal Müller cells cultured in high glucose |
| Q35055667 | Regulated in development and DNA damage 1 is necessary for hyperglycemia-induced vascular endothelial growth factor expression in the retina of diabetic rodents |
| Q36380233 | Subconjunctivally Implanted Hydrogels for Sustained Insulin Release to Reduce Retinal Cell Apoptosis in Diabetic Rats |
| Q35767145 | Topical Application of Insulin Accelerates Vessel Maturation of Wounds by Regulating Angiopoietin-1 in Diabetic Mice |
| Q35868411 | Transgenic Mice Overexpressing Serum Retinol-Binding Protein Develop Progressive Retinal Degeneration through a Retinoid-Independent Mechanism |
| Q34077374 | mTORC1-independent reduction of retinal protein synthesis in type 1 diabetes |
Search more.