NPM1 deletion is associated with gross chromosomal rearrangements in leukemia

scientific article (publication date: 21 September 2010)

NPM1 deletion is associated with gross chromosomal rearrangements in leukemia is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2010PLoSO...512855L
P356DOI10.1371/JOURNAL.PONE.0012855
P8608Fatcat IDrelease_yqexioz3r5en5glc2wsqkcc5um
P932PMC publication ID2943467
P698PubMed publication ID20877721
P5875ResearchGate publication ID46579814

P50authorGiuseppe SaglioQ53342434
Brunangelo FaliniQ30119395
P2093author name stringRoberta La Starza
Valentina Pierini
Cristina Mecucci
Massimo Fabrizio Martelli
Barbara Crescenzi
Caterina Matteucci
Lucia Brandimarte
Paolo Gorello
Roberto Rosati
Laura Berchicci
Enrico Gottardi
Francesco Arcioni
Antonella Santucci
Constantina Sambani
Anna Aventin
Valeria Nofrini
P2860cites work5q- myelodysplastic syndromes: chromosome 5q genes direct a tumor-suppression network sensing actin dynamics.Q37549908
Delineation by molecular cytogenetics of 5q deletion breakpoints in myelodyplastic syndromes and acute myeloid leukemiaQ47207273
TP53 gene mutation is frequent in patients with acute myeloid leukemia and complex karyotype, and is associated with very poor prognosis.Q50629545
Loss of the NPM1 gene in myeloid disorders with chromosome 5 rearrangements.Q54627394
Submicroscopic deletions in 5q- associated malignanciesQ57135685
Narrowing and genomic annotation of the commonly deleted region of the 5q- syndromeQ63248769
Fluorescence in situ hybridization analysis of 110 hematopoietic disorders with chromosome 5 abnormalities: do de novo and therapy-related myelodysplastic syndrome-acute myeloid leukemia actually differ?Q80491212
Molecular characterization of acute myeloid leukemiaQ81555522
Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotypeQ27824827
Prevalence and prognostic impact of NPM1 mutations in 1485 adult patients with acute myeloid leukemia (AML).Q27824861
DNA damage, p14ARF, nucleophosmin (NPM/B23), and cancerQ28253026
Role of nucleophosmin in embryonic development and tumorigenesisQ28591282
Nucleophosmin is required for DNA integrity and p19Arf protein stabilityQ28593126
Evaluation of candidate control genes for diagnosis and residual disease detection in leukemic patients using 'real-time' quantitative reverse-transcriptase polymerase chain reaction (RQ-PCR) - a Europe against cancer program.Q31012437
Integrated genomic analysis implicates haploinsufficiency of multiple chromosome 5q31.2 genes in de novo myelodysplastic syndromes pathogenesisQ33412120
A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndromeQ33579912
Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease. Report of the BIOMED-1 Concerted Action: investigation of minimal residual disease in acute leukemiaQ33797115
Distinct haematological disorder with deletion of long arm of no. 5 chromosomeQ34209827
Nucleophosmin, HDM2 and p53: players in UV damage incited nucleolar stress response.Q34549318
Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotypeQ35011883
Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - a Europe Against Cancer program.Q35561038
Cellular UV damage responses--functions of tumor suppressor p53.Q36142296
Nucleophosmin and cancerQ36516405
Alternative genetic pathways and cooperating genetic abnormalities in the pathogenesis of therapy-related myelodysplasia and acute myeloid leukemiaQ36600942
Deletion 5q in myelodysplastic syndrome: a paradigm for the study of hemizygous deletions in cancerQ37423777
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
P304page(s)e12855
P577publication date2010-09-21
P1433published inPLOS OneQ564954
P1476titleNPM1 deletion is associated with gross chromosomal rearrangements in leukemia
P478volume5

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cites work (P2860)
Q91106400Acute myeloid leukemia with isolated del(5q) is associated with IDH1/IDH2 mutations and better prognosis when compared to acute myeloid leukemia with complex karyotype including del(5q)
Q87226130Association of the type of 5q loss with complex karyotype, clonal evolution, TP53 mutation status, and prognosis in acute myeloid leukemia and myelodysplastic syndrome
Q43160323Different boundaries characterize isolated and non-isolated 5q deletions in myelodysplastic syndromes and acute myeloid leukemias
Q42672788Effect of nucleophosmin1 haploinsufficiency on hematopoietic stem cells
Q37718403NPM1 Gene Type A Mutation in Bulgarian Adults with Acute Myeloid Leukemia: A Single-Institution Study
Q42724172NPM1 gene deletions in myelodysplastic syndromes with 5q- and complex karyotype
Q38527837Recent Advances in the 5q- Syndrome
Q35925259Topography, clinical, and genomic correlates of 5q myeloid malignancies revisited
Q37923939Update on cytogenetic and molecular changes in myelodysplastic syndromes

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