Evaluation of candidate control genes for diagnosis and residual disease detection in leukemic patients using 'real-time' quantitative reverse-transcriptase polymerase chain reaction (RQ-PCR) - a Europe against cancer program.

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Evaluation of candidate control genes for diagnosis and residual disease detection in leukemic patients using 'real-time' quantitative reverse-transcriptase polymerase chain reaction (RQ-PCR) - a Europe against cancer program. is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1042771660
P356DOI10.1038/SJ.LEU.2403136
P698PubMed publication ID14562124
P5875ResearchGate publication ID9048596

P50authorPeter HoklandQ37830927
Giuseppe SaglioQ53342434
Eric DelabesseQ57287418
Jacques Van DongenQ60655923
P2093author name stringDee R
Bi W
van der Velden VH
Lion T
Watzinger F
Gottardi E
Pallisgaard N
Beillard E
Gabert J
Macintyre E
van der Schoot E
P2860cites workCyclophilin A, the Major Intracellular Receptor for the Immunosuppressant Cyclosporin A, Maps to Chromosome 7p11.2-p13: Four Pseudogenes Map to Chromosomes 3, 10, 14, and 18Q24314870
Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assaysQ28140044
Quantitative monitoring of the PRAME gene for the detection of minimal residual disease in leukaemiaQ28212054
Identification and analysis of over 2000 ribosomal protein pseudogenes in the human genomeQ28775742
Current recommendations for positive controls in RT-PCR assaysQ34309821
Outcome prediction in childhood acute lymphoblastic leukaemia by molecular quantification of residual disease at the end of inductionQ34321881
X-chromosome inactivation and human genetic diseaseQ35062073
Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - a Europe Against Cancer program.Q35561038
Human glyceraldehyde-3-phosphate dehydrogenase pseudogenes: molecular evolution and a possible mechanism for amplificationQ35702854
Rapid and sensitive minimal residual disease detection in acute leukemia by quantitative real-time RT-PCR exemplified by t(12;21) TEL-AML1 fusion transcriptQ38319141
Detection and quantification of CBFB/MYH11 fusion transcripts in patients with inv(16)-positive acute myeloblastic leukemia by real-time RT-PCR.Q40821721
Molecular analysis of transferrin receptor mRNA expression in acute myeloid leukaemiaQ43808451
Kinetics of BCR-ABL fusion transcript levels in chronic myeloid leukemia patients treated with STI571 measured by quantitative real-time polymerase chain reactionQ43901112
Quantitative analysis of beta-actin, beta-2-microglobulin and porphobilinogen deaminase mRNA and their comparison as control transcripts for RT-PCR.Q43989560
Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia. European Organization for Research and Treatment of Cancer--Childhood Leukemia Cooperative GroupQ47330036
Quantification of CBFbeta/MYH11 fusion transcript by real time RT-PCR in patients with INV(16) acute myeloid leukemiaQ49279553
Early detection of relapse after bone marrow transplantation in patients with chronic myelogenous leukaemia.Q50751273
Prognostic value of minimal residual disease in acute lymphoblastic leukaemia in childhood.Q53349829
Comparison of chromosome banding analysis, interphase- and hypermetaphase-FISH, qualitative and quantitative PCR for diagnosis and for follow-up in chronic myeloid leukemia: a study on 350 cases.Q55035685
Mechanisms of differential transferrin receptor expression in normal hematopoiesisQ57616766
Accurate and rapid analysis of residual disease in patients with CML using specific fluorescent hybridization probes for real time quantitative RT-PCRQ58455808
BIOMED-1 concerted action report: flow cytometric immunophenotyping of precursor B-ALL with standardized triple-stainingsQ61939586
Human beta-actin retropseudogenes interfere with RT-PCRQ71544442
Debate round-table. Appropriate controls for RT-PCRQ73401605
Quantitation of minimal residual disease in acute promyelocytic leukemia patients with t(15;17) translocation using real-time RT-PCRQ73446193
Normalizing complementary DNA by quantitative reverse transcriptase-polymerase chain reaction of beta2-microglobulin: molecular monitoring of minimal residual disease in acute promyelocytic leukemiaQ73887103
Quantitative analysis of TEL/AML1 fusion transcripts by real-time RT-PCR assay in childhood acute lymphoblastic leukemiaQ74171306
Assessment of minimal residual disease (MRD) in CBFbeta/MYH11-positive acute myeloid leukemias by qualitative and quantitative RT-PCR amplification of fusion transcriptsQ74213181
Immunological detection of minimal residual disease in children with acute lymphoblastic leukaemiaQ74282286
The significance of bcr-abl molecular detection in chronic myeloid leukemia patients "late," 18 months or more after transplantationQ74459267
Detection of minimal residual disease in patients with AML1/ETO-associated acute myeloid leukemia using a novel quantitative reverse transcription polymerase chain reaction assayQ77299371
Identification and validation of endogenous reference genes for expression profiling of T helper cell differentiation by quantitative real-time RT-PCRQ77299611
Screening for core binding factor gene rearrangements in acute myeloid leukemiaQ78035259
P433issue12
P921main subjectleukemiaQ29496
diagnosisQ16644043
P304page(s)2474-2486
P577publication date2003-12-01
P1433published inLeukemiaQ6534498
P1476titleEvaluation of candidate control genes for diagnosis and residual disease detection in leukemic patients using 'real-time' quantitative reverse-transcriptase polymerase chain reaction (RQ-PCR) - a Europe against cancer program
P478volume17

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Q43214271OGG1 is a novel prognostic indicator in acute myeloid leukaemia
Q33781178Olfactory stem cells, a new cellular model for studying molecular mechanisms underlying familial dysautonomia
Q33956085Outcomes in patients with relapsed or refractory acute promyelocytic leukemia treated with or without autologous or allogeneic hematopoietic stem cell transplantation
Q40330608P210 Bcr-abl tyrosine kinase interaction with histone deacetylase 1 modifies histone H4 acetylation and chromatin structure of chronic myeloid leukaemia haematopoietic progenitors
Q35955221PI3K inhibition synergizes with glucocorticoids but antagonizes with methotrexate in T-cell acute lymphoblastic leukemia
Q35576881PINCH-2 expression in cancers involving serosal effusions using quantitative PCR.
Q64926609PPIA, HPRT1, and YWHAZ Genes Are Suitable for Normalization of mRNA Expression in Long-Term Expanded Human Mesenchymal Stem Cells.
Q42623661PRDM16 (1p36) translocations define a distinct entity of myeloid malignancies with poor prognosis but may also occur in lymphoid malignancies
Q53017093PTCH1 expression at diagnosis predicts imatinib failure in chronic myeloid leukaemia patients in chronic phase.
Q92741400Performance Evaluation of the QXDx BCR-ABL %IS Droplet Digital PCR Assay
Q54613497Prediction of relapse by day 100 BCR-ABL quantification after allogeneic stem cell transplantation for chronic myeloid leukemia.
Q41715958Presence of CD34(+)CD38(-)CD58(-) leukemia-propagating cells at diagnosis identifies patients at high risk of relapse with Ph chromosome-positive ALL after allo-hematopoietic SCT.
Q48159027Presence of HLA-DR Molecules and HLA-DRB1 mRNA in Circulating CD4(+) T Cells.
Q38762631Present and future of molecular monitoring in chronic myeloid leukaemia
Q36059184Pretransplantation use of the second-generation tyrosine kinase inhibitors has no negative impact on the HCT outcome
Q36745815Prevalence of interferon type I signature in CD14 monocytes of patients with Sjogren's syndrome and association with disease activity and BAFF gene expression
Q42738559Prognostic Significance of the Lymphoblastic Leukemia-Derived Sequence 1 (LYL1) GeneExpression in Egyptian Patients with AcuteMyeloid Leukemia
Q35986474Prognostic impact of IKZF1 deletion in adults with common B-cell acute lymphoblastic leukemia
Q33886181Prognostic implications of mutations and expression of the Wilms tumor 1 (WT1) gene in adult acute T-lymphoblastic leukemia
Q37148110Prognostic significance of monitoring leukemia-associated immunophenotypes by eight-color flow cytometry in adult B-acute lymphoblastic leukemia
Q51151301Prognostic value of ZAP-70 expression in chronic lymphocytic leukemia as assessed by quantitative polymerase chain reaction and flow cytometry.
Q61053580Prospective multicentric molecular study for poor prognosis fusion transcripts at diagnosis in adult B-lineage ALL patients: the LALA 94 experience
Q37696313Protocol for qRT-PCR analysis from formalin fixed paraffin embedded tissue sections from diffuse large b-cell lymphoma: Validation of the six-gene predictor score.
Q35887790Pure curcumin decreases the expression of WT1 by upregulation of miR-15a and miR-16-1 in leukemic cells
Q36817650Quality control methods for optimal BCR-ABL1 clinical testing in human whole blood samples
Q37727668Quality of life in chronic myeloid leukaemia patients after haematopoietic cell transplantation pretreated with second-generation tyrosine kinase inhibitors
Q42720643Quantification of PML/RARa transcript after induction predicts outcome in children with acute promyelocytic leukemia
Q80313420Quantitative RT-PCR analysis of sphingolipid metabolic enzymes in acute leukemia and myelodysplastic syndromes
Q30492706Quantitative TaqMan real-time PCR assays for gene expression normalisation in feline tissues
Q82758876Quantitative detection of BCR-ABL fusion gene and its application in monitoring chronic myeloid leukemia treatment
Q98772371Quantitative monitoring of minimal residual disease in childhood acute lymphoblastic leukemia using TEL-AML1 fusion transcript as a marker
Q38340772Quantitative monitoring of single nucleotide mutations by allele-specific quantitative PCR can be used for the assessment of minimal residual disease in patients with hematological malignancies throughout their clinical course
Q54516478RET fusion genes are associated with chronic myelomonocytic leukemia and enhance monocytic differentiation.
Q52569573RETRACTED: Arsenic trioxide inhibits proliferation and induced apoptosis of leukemia stem cells with drug resistance.
Q33748792RNA quantification using gold nanoprobes - application to cancer diagnostics
Q34998533RNA-Seq reveals spliceosome and proteasome genes as most consistent transcripts in human cancer cells
Q44052187Rab25 is overexpressed in Müllerian serous carcinoma compared to malignant mesothelioma
Q36600934Rationale for the recommendations for harmonizing current methodology for detecting BCR-ABL transcripts in patients with chronic myeloid leukaemia
Q45405674Readying the minimal residual disease concept in acute myeloid leukaemia for prime time - the American way.
Q54318403Real-time PCR quantification of major Wilms' tumor gene 1 (WT1) isoforms in acute myeloid leukemia, their characteristic expression patterns and possible functional consequences.
Q34861985Real-time assessment of relapse risk based on the WT1 marker in acute leukemia and myelodysplastic syndrome patients after hematopoietic cell transplantation
Q37220846Regulatory T cells in patients with inflammatory bowel diseases treated with adacolumn granulocytapheresis
Q51888520Relapse prediction in acute myeloid leukaemia patients in complete remission using WT1 as a molecular marker: development of a mathematical model to predict time from molecular to clinical relapse and define optimal sampling intervals.
Q34612637Repeated PR1 and WT1 peptide vaccination in Montanide-adjuvant fails to induce sustained high-avidity, epitope-specific CD8+ T cells in myeloid malignancies.
Q54506763Reply to 'What do we mean by sensitivity when we talk about detecting minimal residual disease?' by Steinbach and Debatin.
Q48372855Results of induction chemotherapy in children older than 18 months with stage-4 neuroblastoma treated with an adaptive-to-response modified N7 protocol (mN7).
Q80468804Retrospective comparison of qualitative and quantitative reverse transcriptase polymerase chain reaction in diagnosing and monitoring the ALL1-AF4 fusion transcript in patients with acute lymphoblastic leukaemia
Q47290500Role of treatment in the appearance and selection of BCR-ABL1 kinase domain mutations.
Q41571058Ruxolitinib/nilotinib cotreatment inhibits leukemia-propagating cells in Philadelphia chromosome-positive ALL.
Q51016169SETBP1 mutation analysis in 944 patients with MDS and AML.
Q38022075Sensitivity of minimal residual disease in acute myeloid leukaemia in first remission--methodologies in relation to their clinical situation
Q45173736Serial monitoring of BCR-ABL transcripts in chronic myelogenous leukemia (CML) treated with imatinib mesylate
Q28552969Sphingosine-1-Phosphate Induces Dose-Dependent Chemotaxis or Fugetaxis of T-ALL Blasts through S1P1 Activation
Q92284305Standardisation and consensus guidelines for minimal residual disease assessment in Philadelphia-positive acute lymphoblastic leukemia (Ph + ALL) by real-time quantitative reverse transcriptase PCR of e1a2 BCR-ABL1
Q35561038Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - a Europe Against Cancer program.
Q39992358Standardization of WT1 mRNA quantitation for minimal residual disease monitoring in childhood AML and implications of WT1 gene mutations: a European multicenter study.
Q37662200Standardized MRD quantification in European ALL trials: proceedings of the Second International Symposium on MRD assessment in Kiel, Germany, 18-20 September 2008.
Q38002704Standardized definitions of molecular response in chronic myeloid leukemia.
Q46735722Successful autologous stem cell collection in patients with chronic myeloid leukemia in complete cytogenetic response, with quantitative measurement of BCR-ABL expression in blood, marrow, and apheresis products
Q46730765Suitability of the PAXgene system to stabilize bone marrow RNA in imatinib-resistant patients with chronic myeloid leukemia
Q51743495Survival improvement of poor-prognosis AML/MDS patients by maintenance treatment with low-dose chemotherapy and differentiating agents.
Q39968040Systemic increase in type I interferon activity in Sjögren's syndrome: a putative role for plasmacytoid dendritic cells
Q54335310Systemic mastocytosis is uncommon in KIT D816V mutation positive core-binding factor acute myeloid leukemia.
Q34707452T-cell immune responses to Wilms tumor 1 protein in myelodysplasia responsive to immunosuppressive therapy
Q33765598T-helper 17 cell cytokines and interferon type I: partners in crime in systemic lupus erythematosus?
Q51705397TPMT gene expression is increased during maintenance therapy in childhood acute lymphoblastic leukemia patients in a TPMT gene promoter variable number of tandem repeat-dependent manner.
Q59342678Targeted RNA-sequencing for the quantification of measurable residual disease in acute myeloid leukemia
Q96292691Targeting CD33 in Chemoresistant AML Patient-Derived Xenografts by CAR-CIK Cells Modified with an Improved SB Transposon System
Q92234747Targeting miR-193a-AML1-ETO-β-catenin axis by melatonin suppresses the self-renewal of leukaemia stem cells in leukaemia with t (8;21) translocation
Q33899947Telomerase reverse-transcriptase homozygous mutations in autosomal recessive dyskeratosis congenita and Hoyeraal-Hreidarsson syndrome
Q24649948Tenascin-X is a novel diagnostic marker of malignant mesothelioma
Q55401060The Association between PARP1 and LIG3 Expression Levels and Chromosomal Translocations in Acute Myeloid Leukemia Patients.
Q42479929The Chemorepellent Slit3 Promotes Monocyte Migration
Q47159993The Cks1/Cks2 axis fine-tunes Mll1 expression and is crucial for MLL-rearranged leukaemia cell viability
Q44606506The ETV6/RUNX1 fusion transcript is not detected in RNA isolated from neonatal dried blood spots from children later diagnosed with the corresponding leukemia
Q46931482The JAK2 V617F allele burden in essential thrombocythemia, polycythemia vera and primary myelofibrosis--impact on disease phenotype
Q43006867The assessment of human organic cation transporter 1 (hOCT1) mRNA expression in patients with chronic myelogenous leukemia is affected by the proportion of different cells types in the analyzed cell population
Q38665455The clinical significance of monitoring the expression of the SIL-TAL1 fusion gene in T-cell acute lymphoblastic leukemia after allogeneic hematopoietic stem cell transplantation.
Q37580157The clinical value of the quantitative detection of four cancer-testis antigen genes in multiple myeloma.
Q35717741The composition of the mesenchymal stromal cell compartment in human bone marrow changes during development and aging
Q37628021The dynamics of RUNX1-RUNX1T1 transcript levels after allogeneic hematopoietic stem cell transplantation predict relapse in patients with t(8;21) acute myeloid leukemia
Q41553306The kinetics of relapse in DEK-NUP214-positive acute myeloid leukemia patients
Q84773086The role of TFPI in regulation of TF-induced thrombogenicity on the surface of human monocytes
Q37924989The role of molecular genetic analysis within the diagnostic haemato-oncology laboratory
Q48151269The transcriptomic landscape and directed chemical interrogation of MLL-rearranged acute myeloid leukemias
Q45000807The use of housekeeping genes for real-time PCR-based quantification of fusion gene transcripts in acute myeloid leukemia
Q54489238Three-way translocation (X;20;16)(p11;q13;q23) in essential thrombocythemia implicates NFATC2 in dysregulation of CSF2 expression and megakaryocyte proliferation.
Q52919448Thymic adult T-cell acute lymphoblastic leukemia stratified in standard- and high-risk group by aberrant HOX11L2 expression: experience of the German multicenter ALL study group.
Q44517995Treatment of Ewing sarcoma family of tumors with a modified P6 protocol in children and adolescents
Q35665925Type 2 Diabetes Monocyte MicroRNA and mRNA Expression: Dyslipidemia Associates with Increased Differentiation-Related Genes but Not Inflammatory Activation
Q49299269Type I IFN signature in childhood-onset systemic lupus erythematosus: a conspiracy of DNA- and RNA-sensing receptors?
Q44890063Type and location of isocitrate dehydrogenase mutations influence clinical characteristics and disease outcome of acute myeloid leukemia
Q51904566Utility of urothelial mRNA markers in blood for staging and monitoring bladder cancer.
Q40404105Validation of a digital PCR method for quantification of DNA copy number concentrations by using a certified reference material
Q46917660Valproate enhances imatinib-induced growth arrest and apoptosis in chronic myeloid leukemia cells
Q47594181WT1 gene expression: an excellent tool for monitoring minimal residual disease in 70% of acute myeloid leukaemia patients - results from a single-centre study
Q36736174Why and how to quantify minimal residual disease in acute lymphoblastic leukemia?
Q40035267Wilms tumour gene 1 overexpression in bone marrow as a marker for minimal residual disease in acute myeloid leukaemia
Q54627391Wilms' tumor gene 1 (WT1) expression in childhood acute lymphoblastic leukemia: a wide range of WT1 expression levels, its impact on prognosis and minimal residual disease monitoring.
Q54367385Wilms' tumor gene 1 expression: an independent acute leukemia prognostic indicator following allogeneic hematopoietic SCT.
Q83587561[Linear B-cell epitope prediction]
Q50737622[Prognostic value of dynamic monitoring of RUNX1-RUNX1T1 transcript in pediatric acute myeloid leukemia].
Q89454891[Significance of BCR-ABL fusion gene detection in CD34 (+) cells of chronic myelogenous leukemia patients]
Q42793682beta-Glucuronidase is an optimal normalization control gene for molecular monitoring of chronic myelogenous leukemia
Q44222759hMICL and CD123 in combination with a CD45/CD34/CD117 backbone - a universal marker combination for the detection of minimal residual disease in acute myeloid leukaemia
Q35632171miR-15a and miR-16-1 inhibit the proliferation of leukemic cells by down-regulating WT1 protein level
Q92566885miR-362-5p promotes cell proliferation and cell cycle progression by targeting GAS7 in acute myeloid leukemia

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