FAS (CD95) mutations are rare in gastric MALT lymphoma but occur more frequently in primary gastric diffuse large B-cell lymphoma

scientific article (publication date: March 2004)

FAS (CD95) mutations are rare in gastric MALT lymphoma but occur more frequently in primary gastric diffuse large B-cell lymphoma is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0002-9440(10)63195-1
P932PMC publication ID1614721
P698PubMed publication ID14982861

P50authorMarkus HengstschlägerQ1901560
Georg KrupitzaQ30002284
David SebingerQ114094537
P2093author name stringMargit Rosner
Andreas Chott
Leonhard Müllauer
Markus Raderer
Doris Polgar
Petra Gruber
Judith Buch
Sabine Wohlfart
P2860cites workIdentification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphomaQ24290550
NMR structure and mutagenesis of the Fas (APO-1/CD95) death domainQ27734204
The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunityQ28139188
CD95's deadly mission in the immune systemQ28142072
Resistance of t(11;18) positive gastric mucosa-associated lymphoid tissue lymphoma to Helicobacter pylori eradication therapyQ28200343
Bcl10 is involved in t(1;14)(p22;q32) of MALT B cell lymphoma and mutated in multiple tumor typesQ28297278
The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosisQ29618601
Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosisQ30080034
Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunityQ33488225
The molecular basis for apoptotic defects in patients with CD95 (Fas/Apo-1) mutationsQ33836041
The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa-associated lymphoid tissue lymphomasQ33862984
Activation of apoptosis pathways by anticancer treatment.Q33864763
The gastric marginal zone B-cell lymphoma of MALT type.Q33962393
Gastric MALT lymphoma: from aetiology to treatmentQ34569977
The origin of CD95-gene mutations in B-cell lymphomaQ34584971
A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factorQ34661010
Relationship between high-grade lymphoma and low-grade B-cell mucosa-associated lymphoid tissue lymphoma (MALToma) of the stomachQ35811228
Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)Q41371079
A novel protein domain required for apoptosis. Mutational analysis of human Fas antigenQ41553101
The product of the t(11;18), an API2-MLT fusion, marks nearly half of gastric MALT type lymphomas without large cell proliferationQ42074394
Complete remission of primary high-grade B-cell gastric lymphoma after cure of Helicobacter pylori infectionQ43562732
Prospective study of Helicobacter pylori eradication therapy in stage I(E) high-grade mucosa-associated lymphoid tissue lymphoma of the stomachQ43800133
CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+T cellsQ45971909
Inactivation of the Fas gene by Alu insertion: retrotransposition in an intron causing splicing variation and autoimmune lymphoproliferative syndrome.Q48284203
Fas is required for clonal selection in germinal centers and the subsequent establishment of the memory B cell repertoireQ48377105
Loss of Fas (CD95/APO-1) regulatory function is an important step in early MALT-type lymphoma developmentQ49240035
Somatic Fas mutations in non-Hodgkin's lymphoma: association with extranodal disease and autoimmunity.Q52532296
Lack of CD95/FAS gene somatic mutations in extranodal, nodal and splenic marginal zone B cell lymphomas.Q53412361
Frequent mutations of Fas gene in thyroid lymphoma.Q53895930
Tumor B cells from non-Hodgkin's lymphoma are resistant to CD95 (Fas/Apo-1)-mediated apoptosis.Q54138930
Variable frequencies of t(11;18)(q21;q21) in MALT lymphomas of different sites: significant association with CagA strains of H pylori in gastric MALT lymphoma.Q54780176
MALT1 is deregulated by both chromosomal translocation and amplification in B-cell non-Hodgkin lymphoma.Q54792360
Monoclonal antibody-mediated tumor regression by induction of apoptosis.Q55059937
Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndromeQ55670225
Involvement of the CD95 (APO–1/Fas) receptor/ligand system in drug–induced apoptosis in leukemia cellsQ57384660
Identification and characterisation of polymorphisms in the promoter region of the human Apo-1/Fas (CD95) geneQ61863688
Cytogenetic study of B-cell lymphoma of mucosa-associated lymphoid tissueQ67722602
Gastrointestinal malignant lymphomas of the mucosa-associated lymphoid tissue: factors relevant to prognosisQ68100709
The accumulation of p53 abnormalities is associated with progression of mucosa-associated lymphoid tissue lymphomaQ70837491
Detection of polymorphisms within the Fas cDNA gene sequence by GC-clamp denaturing gradient gel electrophoresisQ71624184
Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liverQ71794021
The t(11;18)(q21;q21) chromosome translocation is a frequent and specific aberration in low-grade but not high-grade malignant non-Hodgkin's lymphomas of the mucosa-associated lymphoid tissue (MALT-) typeQ73722532
BCL10 gene mutation in lymphomaQ73877021
T(14;18)(q32;q21) involving IGH and MALT1 is a frequent chromosomal aberration in MALT lymphomaQ78447749
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectMALT lymphomaQ591256
diffuse large B-cell lymphomaQ2626074
gastric diffuse large B-cell lymphomaQ55780047
P304page(s)1081-9
P577publication date2004-03-01
P1433published inThe American Journal of PathologyQ4744259
P1476titleFAS (CD95) mutations are rare in gastric MALT lymphoma but occur more frequently in primary gastric diffuse large B-cell lymphoma
P478volume164

Reverse relations

cites work (P2860)
Q37951369CD95-mediated cell signaling in cancer: mutations and post-translational modulations
Q36297659Clinical significance of standardized uptake value and maximum tumor diameter in patients with primary extranodal diffuse large B cell lymphoma
Q38261966Crosstalk between CTC, Immune System and Hypoxic Tumor Microenvironment
Q46434131Downregulation of Fas gene expression in Sézary syndrome is associated with promoter hypermethylation
Q80543254Fas/Fas ligand gene polymorphism in patients with papillary thyroid cancer in the Turkish population
Q36005932Gastrointestinal lymphoma: where morphology meets molecular biology
Q35974341Genetic lesions in diffuse large B-cell lymphomas
Q52647877High-throughput sequencing of nodal marginal zone lymphomas identifies recurrent BRAF mutations.
Q43276971Identification, characterisation and regulation by CD40 activation of novel CD95 splice variants in CD95-apoptosis-resistant, human, B-cell non-Hodgkin's lymphoma.
Q34579196Immune surveillance of tumors
Q36814969Mutations within the 5' region of FAS/CD95 gene in nodal diffuse large B-cell lymphoma
Q39578363Over-expressed Fas improves the apoptosis of malignant T-cells in vitro and vivo
Q51574456Prognostic significance of CD95, P53, and BCL2 expression in extranodal non-Hodgkin's lymphoma.
Q53116215Prognostic value of Waldeyer's ring involvement of diffuse large B-cell lymphoma treated with R-CHOP.
Q46961792Ras mediates cell survival by regulating tuberin
Q53622635Tuberin activates the proapoptotic molecule BAD.

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