scholarly article | Q13442814 |
P356 | DOI | 10.1016/0092-8674(95)90013-6 |
P698 | PubMed publication ID | 7540117 |
P2093 | author name string | M J Lenardo | |
W Strober | |||
S E Straus | |||
J M Puck | |||
A Y Lin | |||
J K Dale | |||
G H Fisher | |||
F J Rosenberg | |||
L A Middleton | |||
P433 | issue | 6 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | autoimmune lymphoproliferative syndrome | Q1151300 |
apoptotic process | Q14599311 | ||
P304 | page(s) | 935-46 | |
P577 | publication date | 1995-06-16 | |
P1433 | published in | Cell | Q655814 |
P1476 | title | Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome | |
P478 | volume | 81 |
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Q35129735 | Apoptosis and transplantation tolerance. |
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Q34096282 | Apoptosis genes and autoimmunity. |
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Q39568120 | Apoptosis in haematological malignancies |
Q35091131 | Apoptosis in hematological disorders. |
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Q36852224 | Apoptosis signaling pathways and lymphocyte homeostasis |
Q34404597 | Apoptosis, Part II: The role of mutated Fas genes in tumorigenesis. |
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Q34389314 | Autoimmune lymphoproliferative syndrome with defective Fas: genotype influences penetrance |
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Q36974300 | B cells in glomerulonephritis: focus on lupus nephritis. |
Q41312443 | B cells in systemic autoimmune disease: recent insights from Fas-deficient mice and men. |
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Q36763234 | Interaction between glutathione and apoptosis in systemic lupus erythematosus |
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Q37314479 | Membrane-bound Fas ligand requires RIP1 for efficient activation of caspase-8 within the death-inducing signaling complex |
Q36675182 | Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia |
Q28216909 | Mitochondrial hyperpolarization and ATP depletion in patients with systemic lupus erythematosus |
Q41290133 | Molecular and clinical aspects of apoptosis |
Q34647002 | Molecular aspects of primary immunodeficiencies: lessons from cytokine and other signaling pathways. |
Q40885317 | Molecular cloning and characterization of cynomolgus monkey Fas. |
Q42687371 | Molecular cloning of feline Fas antigen and Fas ligand cDNAs |
Q35176380 | Molecular regulation of T lymphocyte homeostasis in the healthy and diseased immune system |
Q34001034 | Molecular steps of cell suicide: an insight into immune senescence |
Q36368090 | Monocyte-mediated tumoricidal activity via the tumor necrosis factor-related cytokine, TRAIL. |
Q37384657 | Monogenic autoimmune diseases: insights into self-tolerance |
Q47869356 | Mutational analysis of Fas ligand gene in human non-Hodgkin lymphoma |
Q37396889 | Mutations in CRADD Result in Reduced Caspase-2-Mediated Neuronal Apoptosis and Cause Megalencephaly with a Rare Lissencephaly Variant |
Q53667090 | Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans. |
Q22010459 | Mutations in the human homologue of mouse dl cause autosomal recessive and dominant hypohidrotic ectodermal dysplasia |
Q45740282 | Myxoma virus expresses a TNF receptor homolog with two distinct functions |
Q35829141 | NRAS mutation causes a human autoimmune lymphoproliferative syndrome. |
Q37670054 | Natural history of autoimmune lymphoproliferative syndrome associated with FAS gene mutations |
Q33863208 | Natural variation in immune responsiveness, with special reference to immunodeficiency and promoter polymorphism in class II MHC genes |
Q92109255 | Navigating the Fas lane to improved cellular therapy for cancer |
Q34239719 | New advances in the diagnosis and treatment of autoimmune lymphoproliferative syndrome |
Q36126352 | New take on comparative immunology: relevance to immunotherapy |
Q34941147 | Nitric oxide as an inflammatory mediator in autoimmune MRL-lpr/lpr mice |
Q34242689 | Nitric oxide synthase 2 and cyclooxygenase 2 interactions in inflammation |
Q56908682 | Non-HLA genes and the susceptibility to insulin dependent diabetes: the role of the CTLA-4 gene |
Q35557615 | Non-apoptotic functions of caspases in cellular proliferation and differentiation |
Q34415756 | Nonlymphoid Fas ligand in peptide-induced peripheral lymphocyte deletion |
Q37248354 | Novel molecular and cellular therapeutic targets in acute lymphoblastic leukemia and lymphoproliferative disease |
Q34397101 | Of mice and men: the relevance of the mouse to the study of human SLE. |
Q73590802 | Oligoclonal expansion of CD45RO+ T lymphocytes in Omenn syndrome |
Q33541431 | On costimulatory signals and T cell tolerance: relevance for transplantation immunity. |
Q34428954 | Onset of autoimmune lymphoproliferative syndrome (ALPS) in humans as a consequence of genetic defect accumulation |
Q38823961 | Optimal Management of Autoimmune Lymphoproliferative Syndrome in Children |
Q89977010 | Oral Microbes and Mucosal Dendritic Cells, "Spark and Flame" of Local and Distant Inflammatory Diseases |
Q73348111 | Over-expression of the decoy receptor 3 (DcR3) gene in peripheral blood mononuclear cells (PBMC) derived from silicosis patients |
Q37691426 | Overexpression of Mcl-1 exacerbates lymphocyte accumulation and autoimmune kidney disease in lpr mice. |
Q42252275 | Overexpression of membrane-bound fas ligand (CD95L) exacerbates autoimmune disease and renal pathology in pristane-induced lupus. |
Q37798037 | PKC-θ is a Drug Target for Prevention of T Cell-Mediated Autoimmunity and Allograft Rejection |
Q64892906 | Paradoxical CD4 Lymphopenia in Autoimmune Lymphoproliferative Syndrome (ALPS). |
Q33383468 | Pathobiology of secondary immune thrombocytopenia |
Q35257857 | Pathogenesis of juvenile chronic arthritis: genetic and environmental factors |
Q35754536 | Pathological findings in human autoimmune lymphoproliferative syndrome |
Q38200384 | Pathophysiology and spectrum of diseases caused by defects in lymphocyte cytotoxicity. |
Q36148396 | Paths to understanding the genetic basis of autoimmune disease |
Q41514577 | Pathways leading to cell death in T cells |
Q28204372 | Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency |
Q29620319 | Points of control in inflammation |
Q40666242 | Porcine Fas-ligand gene: genomic sequence analysis and comparison with human gene. |
Q52571131 | Possible Association of Multicentric Castleman's Disease with Autoimmune Lymphoproliferative Syndrome. |
Q31104620 | Precise mapping of the CD95 pre-ligand assembly domain |
Q73315105 | Prediction of the three-dimensional structure of the human Fas receptor by comparative molecular modeling |
Q39232124 | Primary/Congenital Immunodeficiency: 2015 SH/EAHP Workshop Report-Part 5. |
Q41894662 | Pro- and anti-apoptotic CD95 signaling in T cells |
Q33847243 | Probiotic sonicates selectively induce mucosal immune cells apoptosis through ceramide generation via neutral sphingomyelinase |
Q79828647 | Prognostic significance of the Fas-receptor/Fas-ligand system in cervical squamous cell carcinoma |
Q46163524 | Programmed cell death (apoptosis) in cord blood lymphocytes |
Q39120700 | Programmed cell death and the immune system |
Q37773421 | Programmed cell death of dendritic cells in immune regulation |
Q45888106 | Programmed cell death: the influence of CD40, CD95 (Fas or Apo-I) and their ligands |
Q36659578 | Proteasome regulation of activation-induced T cell death |
Q38076413 | Protecting and rescuing the effectors: roles of differentiation and survival in the control of memory T cell development |
Q37950926 | RIP1-mediated regulation of lymphocyte survival and death responses |
Q40245571 | Rapid CD40-mediated rescue from CD95-induced apoptosis requires TNFR-associated factor-6 and PI3K. |
Q41728141 | Recent advances. Immunology |
Q41737516 | Receptors and ligands that mediate activation-induced death of T cells |
Q36375186 | Recombinant galectin-1 and its genetic delivery suppress collagen-induced arthritis via T cell apoptosis |
Q90041758 | Regulation of B-cell function by NF-kappaB c-Rel in health and disease |
Q23910429 | Regulation of Fas (CD95)-induced apoptosis by nuclear factor-KB and tumor necrosis factor- alpha in macrophages |
Q28592335 | Regulation of Fas ligand expression and cell death by apoptosis-linked gene 4 |
Q37306636 | Regulation of Fas-mediated immune homeostasis by an activation-induced protein, Cyclon. |
Q36368347 | Regulation of fas ligand expression during activation-induced cell death in T cells by p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase. |
Q36562855 | Regulatory T cells in human autoimmune diseases |
Q42436232 | Regulatory role of CD95 ligation on human B cells induced in vivo capable of spontaneous and high-rate Ig secretion |
Q57384656 | Resistance of cultured peripheral T cells towards activation-induced cell death involves a lack of recruitment of FLICE (MACH/caspase 8) to the CD95 death-inducing signaling complex |
Q40826064 | Resistance to CD95-mediated apoptosis through constitutive c-FLIP expression in a non-Hodgkin's lymphoma B cell line. |
Q35125091 | Review: Environmental exposure to mercury and its toxicopathologic implications for public health |
Q24632569 | Revised diagnostic criteria and classification for the autoimmune lymphoproliferative syndrome (ALPS): report from the 2009 NIH International Workshop |
Q33376403 | Rituximab responsive immune thrombocytopenic purpura in an adult with underlying autoimmune lymphoproliferative syndrome due to a splice-site mutation (IVS7+2 T>C) affecting the Fas gene |
Q41102922 | Role of Fas-mediated cell death in the regulation of immune responses |
Q35084896 | Role of endogenous retroviruses in autoimmune diseases |
Q35107838 | Role of inherited defects decreasing Fas function in autoimmunity. |
Q37365961 | Roles of interferon-gamma and interleukin-4 in murine lupus |
Q36322794 | SPOTS: signaling protein oligomeric transduction structures are early mediators of death receptor-induced apoptosis at the plasma membrane |
Q41399533 | Searching for genes involved in the pathogenesis of primary immunodeficiency diseases: lessons from mouse knockouts |
Q37377927 | Sequential decisions on FAS sequencing guided by biomarkers in patients with lymphoproliferation and autoimmune cytopenia |
Q33588768 | Serum markers of apoptosis decrease with age and cancer stage |
Q34563012 | Signaling to gene activation and cell death by tumor necrosis factor receptors and Fas. |
Q74556952 | Significant role of Fas ligand-binding but defective Fas receptor (CD95) in lymph node hyperplasia composed of abnormal double-negative T cells |
Q77312788 | Soluble Fas mRNA is dominantly expressed in cases with silicosis |
Q34149957 | Somatic KRAS mutations associated with a human nonmalignant syndrome of autoimmunity and abnormal leukocyte homeostasis |
Q41908763 | Somatic mutation of the CD95 gene in human B cells as a side-effect of the germinal center reaction |
Q35092629 | Specific elimination of effector memory CD4+ T cells due to enhanced Fas signaling complex formation and association with lipid raft microdomains |
Q36400965 | Spontaneous development of plasmacytoid tumors in mice with defective Fas-Fas ligand interactions |
Q43014937 | Structural insight for the roles of fas death domain binding to FADD and oligomerization degree of the Fas-FADD complex in the death-inducing signaling complex formation: a computational study |
Q41276439 | Suicide by order: some open questions about the cell-killing activities of the TNF ligand and receptor families |
Q47611305 | Survival of autoreactive T lymphocytes by microRNA-mediated regulation of apoptosis through TRAIL and Fas in type 1 diabetes. |
Q35183209 | Survival signals in leukemic large granular lymphocytes |
Q77892082 | Susceptibility to lupus nephritis in the NZB/W model system |
Q35148616 | Systemic lupus erythematosus and apoptosis: a question of balance |
Q34082803 | Systemic lupus erythematosus, complement deficiency, and apoptosis |
Q36399210 | T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis |
Q36473831 | T cell-tumor cell: a fatal interaction? |
Q34093608 | T-cell receptor complex is essential for Fas signal transduction. |
Q34716347 | T-cell signalling and autoimmunity: molecular mechanisms of disease |
Q39877053 | T-lymphocyte downregulation after acute viral infection is not dependent on CD95 (Fas) receptor-ligand interactions. |
Q73411964 | TCR stimulation protects CD8+ T cells from CD95 mediated apoptosis |
Q59783966 | TNF-related ligands and their receptors |
Q33971049 | TNFRSF1A mutations and autoinflammatory syndromes |
Q64900451 | TRAIL and FasL Functions in Cancer and Autoimmune Diseases: Towards an Increasing Complexity. |
Q30988219 | TRAIL death receptor-4, decoy receptor-1 and decoy receptor-2 expression on CD8+ T cells correlate with the disease severity in patients with rheumatoid arthritis |
Q64078760 | TRAIL-R1 and TRAIL-R2 Mediate TRAIL-Dependent Apoptosis in Activated Primary Human B Lymphocytes |
Q37111489 | Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network |
Q71794021 | Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liver |
Q35577256 | The "fuzzy logic" of the death-inducing signaling complex in lymphocytes |
Q57078448 | The Autoimmune Lymphoproliferative Syndrome with Defective FAS or FAS-Ligand Functions |
Q35031256 | The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions |
Q33533982 | The CD95(APO-1/Fas)/CD95L system |
Q34047933 | The Caenorhabditis elegans mucolipin-like gene cup-5 is essential for viability and regulates lysosomes in multiple cell types |
Q54967366 | The Effect of a Competitive Futsal Match on T Lymphocyte Surface Receptor Signaling and Functions. |
Q36367323 | The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand |
Q41515265 | The Fas pathway in apoptosis. |
Q24302236 | The Fas-FADD death domain complex structure reveals the basis of DISC assembly and disease mutations |
Q24621785 | The Fas-associated death domain protein is required in apoptosis and TLR-induced proliferative responses in B cells |
Q36114138 | The Fas/CD95 Receptor Regulates the Death of Autoreactive B Cells and the Selection of Antigen-Specific B Cells |
Q34459289 | The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens |
Q44196945 | The anti-inflammatory sesquiterpene lactone parthenolide suppresses CD95-mediated activation-induced-cell-death in T-cells |
Q37294307 | The apoptotic members CD95, BclxL, and Bcl-2 cooperate to promote cell migration by inducing Ca(2+) flux from the endoplasmic reticulum to mitochondria |
Q34195490 | The autoimmune lymphoproliferative syndrome. A disorder of human lymphocyte apoptosis |
Q28264600 | The autoimmune lymphoproliferative syndrome: an experiment of nature involving lymphocyte apoptosis |
Q25256839 | The cancer stem cell: evidence for its origin as an injured autoreactive T cell |
Q34283820 | The caspase 8 inhibitor c-FLIP(L) modulates T-cell receptor-induced proliferation but not activation-induced cell death of lymphocytes |
Q77577103 | The clinical spectrum in a large kindred with autoimmune lymphoproliferative syndrome caused by a Fas mutation that impairs lymphocyte apoptosis |
Q40707239 | The conformational alteration of the mutated extracellular domain of Fas in an adult T cell leukemia cell line |
Q42067854 | The death domain of FADD is essential for embryogenesis, lymphocyte development, and proliferation |
Q33996534 | The death domain superfamily in intracellular signaling of apoptosis and inflammation |
Q35116679 | The death effector domain protein family: regulators of cellular homeostasis |
Q37828761 | The emergence of ADAM10 as a regulator of lymphocyte development and autoimmunity |
Q34573771 | The enemy within: keeping self-reactive T cells at bay in the periphery |
Q39805021 | The expression of Fas Ligand by macrophages and its upregulation by human immunodeficiency virus infection. |
Q35855040 | The genetics of familial lymphomas |
Q37989934 | The immunogenetic architecture of autoimmune disease |
Q34205697 | The many roles of FAS receptor signaling in the immune system |
Q33836041 | The molecular basis for apoptotic defects in patients with CD95 (Fas/Apo-1) mutations |
Q41692805 | The molecular basis of intractable diarrhoea of infancy |
Q24685932 | The molecular pathology of primary immunodeficiencies |
Q28139188 | The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity |
Q34584971 | The origin of CD95-gene mutations in B-cell lymphoma |
Q36401438 | The peripheral deletion of autoreactive CD8+ T cells induced by cross-presentation of self-antigens involves signaling through CD95 (Fas, Apo-1). |
Q34009654 | The power and the promise of restimulation-induced cell death in human immune diseases |
Q34071289 | The pre-ligand binding assembly domain: a potential target of inhibition of tumour necrosis factor receptor function |
Q74012642 | The regulation of FasL expression--a distinquishing feature between monocytes and T lymphocytes/NK cells with possible implications for SLE |
Q33636111 | The role of Fas and related death receptors in autoimmune and other disease states |
Q73205341 | The role of Fas in autoimmune diabetes |
Q33898921 | The role of fas ligand in vivo as a cause and regulator of pathogenesis |
Q41659044 | The role of the bcl-2/ced-9 gene family in cancer and general implications of defects in cell death control for tumourigenesis and resistance to chemotherapy |
Q71066518 | The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance |
Q33500825 | The spectrum of Evans' syndrome |
Q64044425 | The technological transformation of patient-driven human immunology research |
Q37852758 | The tumour necrosis factor/TNF receptor superfamily: therapeutic targets in autoimmune diseases |
Q33955244 | Thyroid cell apoptosis. A new understanding of thyroid autoimmunity |
Q41850711 | Trifluoperazine regulation of calmodulin binding to Fas: a computational study |
Q40975748 | Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. |
Q74497763 | Up-regulation of Fas ligand (FasL) mRNA expression in peripheral blood mononuclear cells (PBMC) after major surgery |
Q35575327 | Update on primary immunodeficiency: defects of lymphocytes |
Q33420245 | Updated Understanding of Autoimmune Lymphoproliferative Syndrome (ALPS). |
Q24643047 | Use of rituximab for refractory cytopenias associated with autoimmune lymphoproliferative syndrome (ALPS) |
Q34809111 | Variations of the UNC13D gene in patients with autoimmune lymphoproliferative syndrome |
Q36880053 | Vitamin E and apoptosis |
Q24309135 | Whole-exome-sequencing-based discovery of human FADD deficiency |
Q41688188 | Why do defects in the Fas-Fas ligand system cause autoimmunity? |
Q73047439 | [Thymus: old gland, new ideas] |
Q36405075 | cFLIP regulation of lymphocyte activation and development |
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