Fas-mediated suicide of tumor-reactive T cells following activation by specific tumor: selective rescue by caspase inhibition

scientific article

Fas-mediated suicide of tumor-reactive T cells following activation by specific tumor: selective rescue by caspase inhibition is …
instance of (P31):
scholarly articleQ13442814

External links are
P932PMC publication ID2239009
P698PubMed publication ID10092779

P2093author name stringS A Rosenberg
N P Restifo
T Z Zaks
D B Chappell
P2860cites workCaspases are activated in a branched protease cascade and control distinct downstream processes in Fas-induced apoptosisQ24647389
Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicityQ24680778
Tumour-infiltrating lymphocytes bear the 75 kDa tumour necrosis factor receptorQ36080342
Expression of Fas ligand in liver metastases of human colonic adenocarcinomasQ36186304
Systemic injection of a tripeptide inhibits the intracellular activation of CPP32-like proteases in vivo and fully protects mice against Fas-mediated fulminant liver destruction and deathQ36367540
Different interleukin-1 beta converting enzyme (ICE) family protease requirements for the apoptotic death of T lymphocytes triggered by diverse stimuliQ36377464
T cell receptor signals enhance susceptibility to Fas-mediated apoptosisQ36380957
Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicityQ36400613
Human melanoma cells do not express Fas (Apo-1/CD95) ligandQ36454464
Human lung carcinomas express Fas ligand.Q41120854
Fas/APO-1 (CD95)-mediated cytotoxicity is responsible for the apoptotic cell death of leukaemic cells induced by interleukin-2-activated T cellsQ41142242
Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.Q41284156
Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)Q41371079
The molecular regulation of lymphocyte apoptosisQ41433490
The role of the Caspase family of cysteine proteases in apoptosisQ41433521
Patterns of relapse and response to retreatment in patients with metastatic melanoma or renal cell carcinoma who responded to interleukin-2-based immunotherapyQ41734221
Caspase activity is required for commitment to Fas-mediated apoptosis.Q42623004
Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation.Q42830166
Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosisQ43539775
Expansion of human tumor infiltrating lymphocytes for use in immunotherapy trialsQ44098509
Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas.Q46925453
Human melanoma-reactive CD4+ and CD8+ CTL clones resist Fas ligand-induced apoptosis and use Fas/Fas ligand-independent mechanisms for tumor killing.Q47757272
Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndromeQ55670225
Cytotoxic T-cell-derived granzyme B activates the apoptotic protease ICE-LAP3Q59156995
Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escapeQ71762882
Treatment of patients with metastatic melanoma with autologous tumor-infiltrating lymphocytes and interleukin 2Q72052802
Recognition of multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regressionQ72133139
Localization of 111indium-labeled tumor infiltrating lymphocytes to tumor in patients receiving adoptive immunotherapy. Augmentation with cyclophosphamide and correlation with responseQ72359898
Target cell lysis by CTL granule exocytosis is independent of ICE/Ced-3 family proteasesQ73103920
Technical note: Aberrant detection of cell surface Fas ligand with anti-peptide antibodiesQ74515314
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectsuicideQ10737
P304page(s)3273-3279
P577publication date1999-03-01
P1433published inJournal of ImmunologyQ3521441
P1476titleFas-mediated suicide of tumor-reactive T cells following activation by specific tumor: selective rescue by caspase inhibition
P478volume162

Reverse relations

cites work (P2860)
Q34046869Building better vaccines: how apoptotic cell death can induce inflammation and activate innate and adaptive immunity
Q35088836CD95 (Fas/APO-1)/CD95L in the gastrointestinal tract: fictions and facts
Q27481056Cancer therapy using a self-replicating RNA vaccine
Q80730504Dissection of spontaneous cytotoxicity by human intestinal intraepithelial lymphocytes: MIC on colon cancer triggers NKG2D-mediated lysis through Fas ligand
Q35922726Effector function of CTLs is increased by irradiated colorectal tumor cells that modulate OX-40L and 4-1BBL and is reversed following dual blockade
Q36403535FASL -844C polymorphism is associated with increased activation-induced T cell death and risk of cervical cancer.
Q34579773Fas ligand and the fate of antitumour cytotoxic T lymphocytes
Q36908627Functional heterogeneity of vaccine-induced CD8(+) T cells
Q77834533Immune privilege and FasL: two ways to inactivate effector cytotoxic T lymphocytes by FasL-expressing cells
Q24814703Immunologic aspect of ovarian cancer and p53 as tumor antigen
Q33709232Immunotherapy for solid tumors--a review for surgeons
Q43054155Kainate-mediated excitotoxicity induces neuronal death in the rat spinal cord in vitro via a PARP-1 dependent cell death pathway (Parthanatos).
Q48112031N-acetyl cysteine protects anti-melanoma cytotoxic T cells from exhaustion induced by rapid expansion via the downmodulation of Foxo1 in an Akt-dependent manner.
Q24551158Natural selection of tumor variants in the generation of "tumor escape" phenotypes
Q35956638Not so Fas: Re-evaluating the mechanisms of immune privilege and tumor escape
Q40403108Role of cytokines in promoting immune escape of FasL-expressing human colon cancer cells
Q36958449T cell receptor-induced activation and apoptosis in cycling human T cells occur throughout the cell cycle
Q37220742Targeting T cells with bispecific antibodies for cancer therapy
Q33844221The future of interleukin-2: enhancing therapeutic anticancer vaccines
Q34100958The role of MHC class I glycoproteins in the regulation of induction of cell death in immunocytes by malignant melanoma cells
Q24794258Therapeutic limitations in tumor-specific CD8+ memory T cell engraftment
Q38057233Tumor-induced CD8+ T-cell dysfunction in lung cancer patients.
Q38798139Tumour-induced apoptosis in human mesothelial cells: a mechanism of peritoneal invasion by Fas Ligand/Fas interaction
Q39575992Turning T cells on: epigenetically enhanced expression of effector T-cell costimulatory molecules on irradiated human tumor cells