| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Daniel H Conrad | |
| Natalia S Chaimowitz | |||
| David R Gibb | |||
| Sheinei J Saleem | |||
| Joel Mathews | |||
| P2860 | cites work | Regulated shedding of transmembrane chemokines by the disintegrin and metalloproteinase 10 facilitates detachment of adherent leukocytes. | Q53548573 |
| ADAM10 regulates FasL cell surface expression and modulates FasL-induced cytotoxicity and activation-induced cell death. | Q53572097 | ||
| Matrix metalloproteinase-7-mediated cleavage of Fas ligand protects tumor cells from chemotherapeutic drug cytotoxicity. | Q54019102 | ||
| Inhibition of fractalkine ameliorates murine collagen-induced arthritis. | Q54692528 | ||
| Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome | Q55670225 | ||
| The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis | Q59276652 | ||
| Membrane-associated metalloproteinase recognized by characteristic cleavage of myelin basic protein: assay and isolation | Q71710419 | ||
| Marked amelioration of established collagen-induced arthritis by treatment with antibodies to CD23 in vivo | Q71803587 | ||
| Critical role of CD23 in allergen-induced bronchoconstriction in a murine model of allergic asthma | Q73046098 | ||
| Increased synovial fluid levels of soluble CD23 are associated with an erosive status in rheumatoid arthritis (RA) | Q73664184 | ||
| The in vitro activity of ADAM-10 is inhibited by TIMP-1 and TIMP-3 | Q73807875 | ||
| Differential chemokine responses and homing patterns of murine TCR alpha beta NKT cell subsets | Q73910691 | ||
| A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1 | Q73958442 | ||
| Importance of CD23 for collagen-induced arthritis: delayed onset and reduced severity in CD23-deficient mice | Q77320477 | ||
| An essential role for ectodomain shedding in mammalian development | Q77544828 | ||
| Notch1 perturbation of hemopoiesis involves non-cell- autonomous modifications | Q77584403 | ||
| ADAM10 is a principal 'sheddase' of the low-affinity immunoglobulin E receptor CD23 | Q79314167 | ||
| Notch activity synergizes with B-cell-receptor and CD40 signaling to enhance B-cell activation | Q79441801 | ||
| NOTCH2 mutations in marginal zone lymphoma | Q81350426 | ||
| Constitutively activated Notch signaling is involved in survival and apoptosis resistance of B-CLL cells | Q81974229 | ||
| Regulation of T cell activation by Notch ligand, DLL4, promotes IL-17 production and Rorc activation | Q95816367 | ||
| Catalytic activity of ADAM8, ADAM15, and MDC-L (ADAM28) on synthetic peptide substrates and in ectodomain cleavage of CD23 | Q24303614 | ||
| The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts | Q24307875 | ||
| The Fas ligand intracellular domain is released by ADAM10 and SPPL2a cleavage in T-cells | Q24308074 | ||
| An endothelial receptor for oxidized low-density lipoprotein | Q24323462 | ||
| Notch1 and Notch2 inhibit myeloid differentiation in response to different cytokines | Q24533662 | ||
| SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10. | Q24601406 | ||
| ADAM, a novel family of membrane proteins containing A Disintegrin And Metalloprotease domain: multipotential functions in cell-cell and cell-matrix interactions | Q24651463 | ||
| The Notch ligand Delta1 is sequentially cleaved by an ADAM protease and gamma-secretase | Q24670362 | ||
| A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells | Q28119154 | ||
| Myeloid-derived suppressor cells as regulators of the immune system | Q28131637 | ||
| A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE | Q28139998 | ||
| Protein kinase C-dependent alpha-secretase competes with beta-secretase for cleavage of amyloid-beta precursor protein in the trans-golgi network | Q28143129 | ||
| CXCL16 is a marker of inflammation, atherosclerosis, and acute coronary syndromes in humans | Q28218369 | ||
| Marginal zone B cells | Q28240061 | ||
| Identification and characterization of a pro-tumor necrosis factor-alpha-processing enzyme from the ADAM family of zinc metalloproteases | Q28249632 | ||
| The transmembrane CXC-chemokine ligand 16 is induced by IFN-gamma and TNF-alpha and shed by the activity of the disintegrin-like metalloproteinase ADAM10 | Q28260407 | ||
| CD23 regulates monocyte activation through a novel interaction with the adhesion molecules CD11b-CD18 and CD11c-CD18 | Q28293946 | ||
| A new class of membrane-bound chemokine with a CX3C motif | Q28303204 | ||
| ADAMs: key components in EGFR signalling and development | Q28305519 | ||
| Inhibition of CX3CL1 (fractalkine) improves experimental autoimmune myositis in SJL/J mice | Q28508318 | ||
| Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand | Q28513283 | ||
| Non-cell autonomous expression of TNF-alpha-converting enzyme ADAM17 is required for normal lymphocyte development | Q28591577 | ||
| Myeloproliferative disease in mice with reduced presenilin gene dosage: effect of gamma-secretase blockage | Q28591999 | ||
| Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis | Q28646378 | ||
| Exosomes: composition, biogenesis and function | Q29547721 | ||
| The canonical Notch signaling pathway: unfolding the activation mechanism | Q29547725 | ||
| Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis | Q30080034 | ||
| Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands | Q30443463 | ||
| Selective roles for tumor necrosis factor alpha-converting enzyme/ADAM17 in the shedding of the epidermal growth factor receptor ligand family: the juxtamembrane stalk determines cleavage efficiency | Q33201079 | ||
| Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity | Q33488225 | ||
| Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia | Q33706334 | ||
| ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo | Q33730084 | ||
| TLR4-mediated signaling induces MMP9-dependent cleavage of B cell surface CD23. | Q34038580 | ||
| Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development | Q34197865 | ||
| The many roles of FAS receptor signaling in the immune system | Q34205697 | ||
| Lymphocyte activation gene-3 (CD223) regulates the size of the expanding T cell population following antigen activation in vivo | Q34315262 | ||
| CD23 Sheddase A disintegrin and metalloproteinase 10 (ADAM10) is also required for CD23 sorting into B cell-derived exosomes | Q34333685 | ||
| Role of LAG-3 in regulatory T cells. | Q34358935 | ||
| ADAM10 mediates ectodomain shedding of the betacellulin precursor activated by p-aminophenylmercuric acetate and extracellular calcium influx | Q34362287 | ||
| Expression of lymphocyte activation gene 3 (LAG-3) on B cells is induced by T cells | Q34428196 | ||
| A disintegrin and metalloproteinase 10-mediated cleavage and shedding regulates the cell surface expression of CXC chemokine ligand 16. | Q34649401 | ||
| CD23: an overlooked regulator of allergic disease. | Q34662928 | ||
| ADAM10 is the constitutive functional sheddase of CD44 in human melanoma cells. | Q34868956 | ||
| Metalloprotease ADAM10 is required for Notch1 site 2 cleavage. | Q35000965 | ||
| The ADAMs family of metalloproteases: multidomain proteins with multiple functions | Q35039313 | ||
| Metalloproteases regulate T-cell proliferation and effector function via LAG-3 | Q35612460 | ||
| Notch regulation of lymphocyte development and function. | Q35676281 | ||
| Inhibition of CXCL16 attenuates inflammatory and progressive phases of anti-glomerular basement membrane antibody-associated glomerulonephritis | Q35757157 | ||
| Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10. | Q35897595 | ||
| Notch1 engagement by Delta-like-1 promotes differentiation of B lymphocytes to antibody-secreting cells | Q36024111 | ||
| Metalloproteinase inhibitors for the disintegrin-like metalloproteinases ADAM10 and ADAM17 that differentially block constitutive and phorbol ester-inducible shedding of cell surface molecules. | Q36074351 | ||
| Notch ligand Delta-like 4 regulates disease pathogenesis during respiratory viral infections by modulating Th2 cytokines | Q36229204 | ||
| Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus. | Q36369494 | ||
| Regulation of lymphocyte development by Notch signaling | Q36794296 | ||
| Modulation of the immune response using dendritic cell-derived exosomes | Q36944603 | ||
| CD44 involvement in autoimmune inflammations: the lesson to be learned from CD44-targeting by antibody or from knockout mice | Q36958322 | ||
| The low affinity IgE receptor (CD23) is cleaved by the metalloproteinase ADAM10. | Q36971361 | ||
| ADAMs 10 and 17 represent differentially regulated components of a general shedding machinery for membrane proteins such as transforming growth factor alpha, L-selectin, and tumor necrosis factor alpha | Q37127274 | ||
| A closer look at alpha-secretase | Q37130663 | ||
| Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia | Q37215995 | ||
| Proteolytic processing of delta-like 1 by ADAM proteases | Q37218310 | ||
| Shedding light on proteolytic cleavage of CD44: the responsible sheddase and functional significance of shedding | Q37381798 | ||
| Untangling the T branch of the hematopoiesis tree | Q37408715 | ||
| A new paradigm for hematopoietic cell lineages: revision of the classical concept of the myeloid-lymphoid dichotomy | Q37438995 | ||
| ADAM10 as a therapeutic target for cancer and inflammation | Q37550839 | ||
| Gain-of-function mutations and copy number increases of Notch2 in diffuse large B-cell lymphoma | Q38354055 | ||
| Selective use of ADAM10 and ADAM17 in activation of Notch1 signaling | Q39808768 | ||
| Notch ligands expressed by follicular dendritic cells protect germinal center B cells from apoptosis | Q39835367 | ||
| Up-regulation of the alpha-secretase ADAM10 by retinoic acid receptors and acitretin | Q39895248 | ||
| Tetraspanins regulate ADAM10-mediated cleavage of TNF-alpha and epidermal growth factor | Q39921892 | ||
| Functional role of N-glycosylation from ADAM10 in processing, localization and activity of the enzyme. | Q39996346 | ||
| Enhancement of alpha-secretase cleavage of amyloid precursor protein by a metalloendopeptidase nardilysin. | Q40122654 | ||
| Sequential processing of the transmembrane chemokines CX3CL1 and CXCL16 by alpha- and gamma-secretases | Q40139487 | ||
| A role for exosomes in the constitutive and stimulus-induced ectodomain cleavage of L1 and CD44 | Q40361195 | ||
| Notch signaling induces multilineage myeloid differentiation and up-regulates PU.1 expression. | Q40646120 | ||
| Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome | Q40744630 | ||
| Notch1-induced delay of human hematopoietic progenitor cell differentiation is associated with altered cell cycle kinetics | Q40977649 | ||
| Binding of anti-CD23 monoclonal antibody to the leucine zipper motif of FcepsilonRII/CD23 on B cell membrane promotes its proteolytic cleavage. Evidence for an effect on the oligomer/monomer equilibrium | Q40993804 | ||
| IgE secretion is attenuated by an inhibitor of proteolytic processing of CD23 (Fc epsilonRII). | Q41065310 | ||
| Purification of ADAM 10 from bovine spleen as a TNFalpha convertase | Q41134978 | ||
| ADAM10, the rate-limiting protease of regulated intramembrane proteolysis of Notch and other proteins, is processed by ADAMS-9, ADAMS-15, and the gamma-secretase | Q42059040 | ||
| Targeting Notch signaling in autoimmune and lymphoproliferative disease | Q42953771 | ||
| Soluble fractalkine in the cerebrospinal fluid of patients with neuropsychiatric lupus | Q42955594 | ||
| Impairment of thymocyte development by dominant-negative Kuzbanian (ADAM-10) is rescued by the Notch ligand, delta-1. | Q46768820 | ||
| The metalloprotease-disintegrin Kuzbanian participates in Notch activation during growth and patterning of Drosophila imaginal discs | Q47072430 | ||
| The role of fractalkine as an accelerating factor on the autoimmune exocrinopathy in mice | Q47905844 | ||
| Inhibition of gamma-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes | Q47993697 | ||
| KUZ, a conserved metalloprotease-disintegrin protein with two roles in Drosophila neurogenesis | Q48060932 | ||
| RECK modulates Notch signaling during cortical neurogenesis by regulating ADAM10 activity | Q48142240 | ||
| Furin is an endogenous regulator of alpha-secretase associated APP processing | Q48433458 | ||
| The neuronal chemokine CX3CL1/fractalkine selectively recruits NK cells that modify experimental autoimmune encephalomyelitis within the central nervous system | Q48554549 | ||
| Delta-like 1 is essential for the maintenance of marginal zone B cells in normal mice but not in autoimmune mice. | Q50654232 | ||
| Notch1 expression in early lymphopoiesis influences B versus T lineage determination. | Q51085324 | ||
| ADAM10 is essential for proteolytic activation of Notch during thymocyte development. | Q51952311 | ||
| Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes. | Q52117223 | ||
| Notch1 is essential for postimplantation development in mice. | Q52512097 | ||
| P433 | issue | 11 | |
| P921 | main subject | lymphocyte | Q715347 |
| P304 | page(s) | 1319-1327 | |
| P577 | publication date | 2011-01-13 | |
| P1433 | published in | Molecular Immunology | Q6895954 |
| P1476 | title | The emergence of ADAM10 as a regulator of lymphocyte development and autoimmunity | |
| P478 | volume | 48 |
| Q36544938 | A CD21 low phenotype, with no evidence of autoantibodies to complement proteins, is consistent with a poor prognosis in CLL |
| Q52404707 | A Role for Soluble IL-6 Receptor in Osteoarthritis. |
| Q39132527 | A disintegrin and metalloproteinase 10 regulates antibody production and maintenance of lymphoid architecture |
| Q40119336 | ADAM10 and Notch1 on murine dendritic cells control the development of type 2 immunity and IgE production. |
| Q34026123 | ADAM10 is required for SCF-induced mast cell migration |
| Q33676656 | ADAM10 is the major sheddase responsible for the release of membrane-associated meprin A. |
| Q34374623 | ADAM10 regulates transcription factor expression required for plasma cell function |
| Q37688489 | Gemcitabine inhibits immune escape of pancreatic cancer by down regulating the soluble ULBP2 protein |
| Q99603753 | Genomic signatures of coevolution between non-model mammals and parasitic roundworms |
| Q41957615 | Identification of genes expressed in the migrating primitive myeloid lineage of Xenopus laevis |
| Q34756662 | Metalloproteinase-dependent TLR2 ectodomain shedding is involved in soluble toll-like receptor 2 (sTLR2) production |
| Q37942089 | Regulation of α-secretase ADAM10 expression and activity |
| Q35487768 | Soluble T cell immunoglobulin mucin domain 3 is shed from CD8+ T cells by the sheddase ADAM10, is increased in plasma during untreated HIV infection, and correlates with HIV disease progression |
| Q92009288 | Stage-dependent involvement of ADAM10 and its significance in epileptic seizures |
| Q91712029 | Targeting ADAM10 in Cancer and Autoimmunity |
| Q37216972 | The ADAMs family of proteases as targets for the treatment of cancer |
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