The CD95(APO-1/Fas)/CD95L system

scientific article

The CD95(APO-1/Fas)/CD95L system is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0378-4274(98)00297-5
P698PubMed publication ID10022244

P2093author name stringKrammer PH
P2860cites workProtection from Fas-mediated apoptosis by a soluble form of the Fas moleculeQ24305174
A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domainQ24306835
FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosisQ24307362
RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell deathQ24307376
Human Fas ligand: gene structure, chromosomal location and species specificityQ24310150
Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell deathQ24311298
Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activationQ27732032
The human APO-1 (APT) antigen maps to 10q23, a region that is syntenic with mouse chromosome 19Q28188657
Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor familyQ28285445
Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligandQ28513283
The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosisQ29618601
The Fas death factorQ29620461
Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunityQ33488225
Role for ceramide as an endogenous mediator of Fas-induced cytotoxicityQ33980970
Fas and Fas ligand in embryos and adult mice: ligand expression in several immune-privileged tissues and coexpression in adult tissues characterized by apoptotic cell turnoverQ36236704
Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage.Q36365423
The role of APO-1-mediated apoptosis in the immune systemQ36677969
Regulation of apoptosis in the immune systemQ36732039
Fas-mediated cytotoxicity--a new immunoregulatory and pathogenic function of Th1 CD4+ T cellsQ40378902
Expression of the functional soluble form of human fas ligand in activated lymphocytes.Q40806057
No evidence for involvement of mouse protein-tyrosine phosphatase-BAS-like Fas-associated phosphatase-1 in Fas-mediated apoptosisQ41075243
Induction of apoptosis in mature T cells by tumour necrosis factorQ41293478
Regulation of cell surface APO-1/Fas (CD95) ligand expression by metalloproteasesQ41321495
Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)Q41371079
Inhibition of apoptosis in T cells expressing human T cell leukemia virus type I Tax.Q41440696
Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase.Q41440948
A novel domain within the 55 kd TNF receptor signals cell deathQ41528172
Expression of APO-1 (CD95), a member of the NGF/TNF receptor superfamily, in normal and neoplastic colon epitheliumQ42808304
Membrane Fas ligand kills human peripheral blood T lymphocytes, and soluble Fas ligand blocks the killingQ42951871
Protection against Fas-dependent Th1-mediated apoptosis by antigen receptor engagement in B cells.Q54177718
Activation interferes with the APO-1 pathway in mature human T cells.Q54239983
Monoclonal antibody-mediated tumor regression by induction of apoptosis.Q55059937
Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndromeQ55670225
Two signaling pathways can lead to Fas ligand expression in CD8+ cytotoxic T lymphocyte clonesQ70911120
Fas ligand in human serumQ71031959
Fas-mediated apoptosis in primary cultured mouse hepatocytesQ71660111
Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liverQ71794021
P304page(s)131-137
P577publication date1998-12-01
P1433published inToxicology LettersQ1796854
P1476titleThe CD95(APO-1/Fas)/CD95L system
P478volume102-103

Reverse relations

cites work (P2860)
Q36216032ABC294640, a sphingosine kinase 2 inhibitor, enhances the antitumor effects of TRAIL in non-small cell lung cancer
Q24536096Caspases: pharmacological manipulation of cell death
Q33717488Cell death induced by the Fas/Fas ligand pathway and its role in pathology
Q51371762Correlation of insulin resistance, beta cell function and insulin sensitivity with serum sFas and sFasL in newly diagnosed type 2 diabetes.
Q43717255Differential sensitivity of human papillomavirus type 16(+) and type 18(+) cervical carcinoma cells to CD95-mediated apoptosis
Q40643770Distinct intracellular signaling in tumor necrosis factor-related apoptosis-inducing ligand- and CD95 ligand-mediated apoptosis
Q43515221Drug resistance does not correlate with resistance to Fas-mediated apoptosis
Q51022799Dysfunctional spermatogenesis in transgenic mice overexpressing bHLH-Zip transcription factor, Spz1.
Q40484694Effects of Shenqi Fuzheng injection on Fas/FasL protein expression levels in the cardiomyocytes of a mouse model of viral myocarditis
Q33566824Enhancement of TRAIL-induced apoptosis by 5-fluorouracil requires activating Bax and p53 pathways in TRAIL-resistant lung cancers
Q21245465Main roads to melanoma
Q28368310Relatively low-dose cyclophosphamide is likely to induce apoptotic cell death in rat thymus through Fas/Fas ligand pathway
Q41114371Role of Programmed Cell Death in the Immunopathogenesis of Sepsis
Q34482821TRAIL/Apo-2L: mechanisms and clinical applications in cancer
Q82897837The effect of bevacizumab on serum soluble FAS/FASL and TRAIL and its receptors (DR4 and DR5) in metastatic colorectal cancer
Q33864774The relevance of spontaneous- and chemically-induced alterations in testicular germ cell apoptosis to toxicology.

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