Oral Multiple Sclerosis Drugs Inhibit the In vitro Growth of Epsilon Toxin Producing Gut Bacterium, Clostridium perfringens

scientific article (publication date: 2017)

Oral Multiple Sclerosis Drugs Inhibit the In vitro Growth of Epsilon Toxin Producing Gut Bacterium, Clostridium perfringens is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FCIMB.2017.00011
P932PMC publication ID5263136
P698PubMed publication ID28180112

P2093author name stringVincent A Fischetti
Timothy K Vartanian
Kareem R Rumah
P2860cites workThe Myelin and Lymphocyte Protein MAL Is Required for Binding and Activity of Clostridium perfringens ε-ToxinQ27319992
Relapsing and remitting multiple sclerosis: pathology of the newly forming lesionQ28253124
On dihydroorotate dehydrogenases and their inhibitors and usesQ28286480
Epsilon toxin: a fascinating pore-forming toxinQ30155565
Long-term effects of delayed-release dimethyl fumarate in multiple sclerosis: Interim analysis of ENDORSE, a randomized extension studyQ33641367
Gambogic acid inhibits proliferation of human lung carcinoma SPC-A1 cells in vivo and in vitro and represses telomerase activity and telomerase reverse transcriptase mRNA expression in the cellsQ33982778
Fingolimod (FTY720): a recently approved multiple sclerosis drug based on a fungal secondary metaboliteQ34174973
Sphingoid long chain bases prevent lung infection by Pseudomonas aeruginosaQ34342508
Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groupsQ34735149
Isolation of Clostridium perfringens type B in an individual at first clinical presentation of multiple sclerosis provides clues for environmental triggers of the diseaseQ35022730
Gut microbiome and multiple sclerosis.Q35245013
Dimethyl fumarate and monoethyl fumarate exhibit differential effects on KEAP1, NRF2 activation, and glutathione depletion in vitroQ35582048
Clostridium perfringens Epsilon Toxin Causes Selective Death of Mature Oligodendrocytes and Central Nervous System DemyelinationQ35753667
Antibacterial activity of sphingoid bases and fatty acids against Gram-positive and Gram-negative bacteria.Q35806462
Multiple sclerosis--the plaque and its pathogenesisQ36410882
Clostridium perfringens toxin genotypes in the feces of healthy North AmericansQ36745087
Identification of New Human Malaria Parasite Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors by Pharmacophore and Structure-Based Virtual ScreeningQ36912176
Menaquinone analogs inhibit growth of bacterial pathogensQ37263504
Teriflunomide and its mechanism of action in multiple sclerosisQ37730005
The interplay between the intestinal microbiota and the brainQ38045736
BG-12 in multiple sclerosisQ38109572
Inhibition of Clostridium botulinum 62A by fumarates and maleates and relationship of activity to some physicochemical constantsQ39923817
Binding of epsilon-toxin from Clostridium perfringens in the nervous systemQ46649465
Epsilon toxin from Clostridium perfringens acts on oligodendrocytes without forming pores, and causes demyelinationQ48495233
Prediction of Michael-Type Acceptor Reactivity toward GlutathioneQ57004060
The availability of sulphur for Clostridium perfringens and an examination of hydrogen sulphide productionQ74456628
Combination therapy in multiple sclerosisQ82972196
P407language of work or nameEnglishQ1860
P921main subjectClostridium perfringensQ309465
P304page(s)11
P577publication date2017-01-01
P1433published inFrontiers in Cellular and Infection MicrobiologyQ27724376
P1476titleOral Multiple Sclerosis Drugs Inhibit the In vitro Growth of Epsilon Toxin Producing Gut Bacterium, Clostridium perfringens
P478volume7

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cites work (P2860)
Q64055465Clostridium perfringens Epsilon Toxin Compromises the Blood-Brain Barrier in a Humanized Zebrafish Model
Q90653232Disease-modifying therapies alter gut microbial composition in MS
Q55236740Gut Microbiota in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis: Current Applications and Future Perspectives.
Q91198966Gut microbiome of treatment-naïve MS patients of different ethnicities early in disease course
Q91673342Gut microbiota composition during a 12-week intervention with delayed-release dimethyl fumarate in multiple sclerosis - a pilot trial
Q39434933Gut-CNS-Axis as Possibility to Modulate Inflammatory Disease Activity-Implications for Multiple Sclerosis
Q92330463Primary progressive multiple sclerosis in a Russian cohort: relationship with gut bacterial diversity
Q88961131The intestinal barrier in multiple sclerosis: implications for pathophysiology and therapeutics

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