| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Matthew Holt | |
| Tom Muir | |||
| P2860 | cites work | A direct method for site-specific protein acetylation | Q84953161 |
| Biochemical profiling of histone binding selectivity of the yeast bromodomain family | Q21142665 | ||
| Crystal structure of the nucleosome core particle at 2.8 A resolution | Q22122355 | ||
| Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions | Q24303887 | ||
| Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB | Q24309403 | ||
| SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53 | Q24310032 | ||
| H3R42me2a is a histone modification with positive transcriptional effects | Q24319807 | ||
| RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells | Q24321262 | ||
| Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification | Q24635918 | ||
| Expressed protein ligation: a general method for protein engineering | Q24657669 | ||
| Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail | Q27638012 | ||
| The language of covalent histone modifications | Q27860931 | ||
| Chromatin modifications and their function | Q27861067 | ||
| Proteome-wide analysis in Saccharomyces cerevisiae identifies several PHD fingers as novel direct and selective binding modules of histone H3 methylated at either lysine 4 or lysine 36. | Q27929914 | ||
| Histone modifications influence the action of Snf2 family remodelling enzymes by different mechanisms | Q27934508 | ||
| Genetically directing ɛ-N, N-dimethyl-L-lysine in recombinant histones | Q42841942 | ||
| Semisynthesis of cytotoxic proteins using a modified protein splicing element | Q42846179 | ||
| Systematic Identification of Methyllysine-Driven Interactions for Histone and Nonhistone Targets | Q42909185 | ||
| Modular strategy for the semisynthesis of a K+ channel: investigating interactions of the pore helix. | Q42931157 | ||
| Protein synthesis assisted by native chemical ligation at leucine | Q43076460 | ||
| A pyrrolysine analogue for site-specific protein ubiquitination | Q43250699 | ||
| Highly efficient and chemoselective peptide ubiquitylation | Q43271585 | ||
| Dual native chemical ligation at lysine | Q43281390 | ||
| Highly specific antibodies determine histone acetylation site usage in yeast heterochromatin and euchromatin | Q43430561 | ||
| Covalent capture: a new tool for the purification of synthetic and recombinant polypeptides | Q43672878 | ||
| Synthesis of peptides and proteins without cysteine residues by native chemical ligation combined with desulfurization | Q43677070 | ||
| Specific antibodies reveal ordered and cell-cycle-related use of histone-H4 acetylation sites in mammalian cells | Q44132037 | ||
| A native peptide ligation strategy for deciphering nucleosomal histone modifications | Q44321482 | ||
| Systematic identification of proteins binding to chromatin-embedded ubiquitylated H2B reveals recruitment of SWI/SNF to regulate transcription. | Q44703962 | ||
| Direct production of proteins with N-terminal cysteine for site-specific conjugation | Q44900286 | ||
| Peptide ligation-desulfurization chemistry at arginine. | Q45217986 | ||
| Convergent chemical synthesis of histone H2B protein for the site-specific ubiquitination at Lys34. | Q45251784 | ||
| N-methylation of isopeptide bond as a strategy to resist deubiquitinases | Q45710972 | ||
| Chemoselective peptide ligation-desulfurization at aspartate | Q45892251 | ||
| Peptide ligation via the in-situ transformation of an amide into a thioester at a cysteine residue. | Q46033733 | ||
| The naturally split Npu DnaE intein exhibits an extraordinarily high rate in the protein trans-splicing reaction | Q46080390 | ||
| Histone H2B (and H2A) ubiquitination allows normal histone octamer and core particle reconstitution | Q46168928 | ||
| Native chemical ligation at valine | Q46484020 | ||
| Genetically encoding N(epsilon)-acetyllysine in recombinant proteins. | Q46751659 | ||
| Free-radical-based, specific desulfurization of cysteine: a powerful advance in the synthesis of polypeptides and glycopolypeptides | Q46875940 | ||
| Mechanism-based inhibition of Sir2 deacetylases by thioacetyl-lysine peptide | Q46890032 | ||
| Acetyl-lysine analog peptides as mechanistic probes of protein deacetylases | Q46939046 | ||
| Native chemical ligation of polypeptides | Q47757953 | ||
| Chemical studies of histone acetylation. Substrate specificity of a histone deacetylase from calf thymus nuclei. | Q47833684 | ||
| Trifluoroethanethiol: an additive for efficient one-pot peptide ligation-desulfurization chemistry. | Q51731846 | ||
| Single-column purification of free recombinant proteins using a self-cleavable affinity tag derived from a protein splicing element | Q56267595 | ||
| Synthesis of ε-N-propionyl-, ε-N-butyryl-, and ε-N-crotonyl-lysine containing histone H3 using the pyrrolysine system | Q57376726 | ||
| Genetically Encoded 1,2-Aminothiols Facilitate Rapid and Site-Specific Protein Labeling via a Bio-orthogonal Cyanobenzothiazole Condensation | Q59319678 | ||
| The leucine zipper domain controls the orientation of AP-1 in the NFAT.AP-1.DNA complex | Q67426632 | ||
| Purification of proteins fused to either the amino or carboxy terminus of the Mycobacterium xenopi gyrase A intein | Q78005223 | ||
| Native chemical ligation at phenylalanine | Q80689458 | ||
| Native chemical ligation through in situ O to S acyl shift | Q81161668 | ||
| Disulfide-directed histone ubiquitylation reveals plasticity in hDot1L activation | Q83148073 | ||
| Insights into the mechanism and catalysis of the native chemical ligation reaction | Q83355026 | ||
| Protein chemical synthesis by ligation of peptide hydrazides | Q84291313 | ||
| A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling | Q28242453 | ||
| Expanding the genetic code of Escherichia coli with phosphoserine | Q28246486 | ||
| The PHD finger/bromodomain of NoRC interacts with acetylated histone H4K16 and is sufficient for rDNA silencing | Q28594882 | ||
| Mapping and analysis of chromatin state dynamics in nine human cell types | Q29547552 | ||
| Active genes are tri-methylated at K4 of histone H3 | Q29547668 | ||
| Partitioning and plasticity of repressive histone methylation states in mammalian chromatin | Q29614513 | ||
| Histone H4-K16 acetylation controls chromatin structure and protein interactions | Q29614521 | ||
| WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development | Q29614526 | ||
| Synthesis of proteins by native chemical ligation | Q29616750 | ||
| Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast | Q29617217 | ||
| A new strategy for glycoprotein synthesis: ligation of synthetic glycopeptides with truncated proteins expressed in E. coli as TEV protease cleavable fusion protein | Q30844999 | ||
| Peptide thioester preparation by Fmoc solid phase peptide synthesis for use in native chemical ligation | Q30872871 | ||
| Epigenome microarray platform for proteome-wide dissection of chromatin-signaling networks | Q30944751 | ||
| Protein engineering by expressed protein ligation | Q30961015 | ||
| Peptide arrays on cellulose support: SPOT synthesis, a time and cost efficient method for synthesis of large numbers of peptides in a parallel and addressable fashion | Q33286526 | ||
| A combinatorial H4 tail library for exploring the histone code | Q33350596 | ||
| Combinatorial profiling of chromatin binding modules reveals multisite discrimination | Q33535222 | ||
| Preparation of fully synthetic histone H3 reveals that acetyl-lysine 56 facilitates protein binding within nucleosomes | Q33817639 | ||
| Synthesis of native proteins by chemical ligation | Q34019420 | ||
| Accelerated chromatin biochemistry using DNA-barcoded nucleosome libraries | Q34034234 | ||
| A program for ligation at threonine sites: application to the controlled total synthesis of glycopeptides | Q34078234 | ||
| Reconstitution of nucleosome core particles from recombinant histones and DNA. | Q34296889 | ||
| Scratching the (lateral) surface of chromatin regulation by histone modifications | Q34348859 | ||
| Multivalent recognition of histone tails by the PHD fingers of CHD5 | Q34352597 | ||
| Peptide microarrays to interrogate the "histone code". | Q34387013 | ||
| A cascade of histone modifications induces chromatin condensation in mitosis. | Q34395441 | ||
| Integrative annotation of chromatin elements from ENCODE data | Q34503932 | ||
| Protein ligation: an enabling technology for the biophysical analysis of proteins | Q34529929 | ||
| Semisynthesis of proteins by expressed protein ligation | Q34531980 | ||
| Auxiliary-mediated site-specific peptide ubiquitylation. | Q34609386 | ||
| Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction | Q34808188 | ||
| A semisynthetic strategy to generate phosphorylated and acetylated histone H2B. | Q34912456 | ||
| Comprehensive analysis of the chromatin landscape in Drosophila melanogaster | Q35030499 | ||
| Histone fold modifications control nucleosome unwrapping and disassembly | Q35149617 | ||
| Histone 2B can be modified by the attachment of ubiquitin | Q35626907 | ||
| Combinatorial complexity in chromatin structure and function: revisiting the histone code | Q35936019 | ||
| Poly-acetylated chromatin signatures are preferred epitopes for site-specific histone H4 acetyl antibodies | Q36072539 | ||
| Histone monoubiquitylation position determines specificity and direction of enzymatic cross-talk with histone methyltransferases Dot1L and PRC2. | Q36078818 | ||
| Facile synthesis of site-specifically acetylated and methylated histone proteins: reagents for evaluation of the histone code hypothesis | Q36348025 | ||
| Enhanced top-down characterization of histone post-translational modifications | Q36378096 | ||
| Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation | Q36381487 | ||
| Asymmetrically modified nucleosomes | Q36401114 | ||
| Ultrafast protein splicing is common among cyanobacterial split inteins: implications for protein engineering | Q36502962 | ||
| Stability of nucleosomes containing homogenously ubiquitylated H2A and H2B prepared using semisynthesis | Q36502967 | ||
| Streamlined expressed protein ligation using split inteins. | Q36530093 | ||
| The n-SET domain of Set1 regulates H2B ubiquitylation-dependent H3K4 methylation | Q36736313 | ||
| Multivalent histone engagement by the linked tandem Tudor and PHD domains of UHRF1 is required for the epigenetic inheritance of DNA methylation | Q36948989 | ||
| Histone tails: ideal motifs for probing epigenetics through chemical biology approaches | Q37139778 | ||
| Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation | Q37175650 | ||
| Site-specific incorporation of ε-N-crotonyllysine into histones | Q37197898 | ||
| Acetylation of histone H3 at the nucleosome dyad alters DNA-histone binding. | Q37358082 | ||
| Structure-activity analysis of semisynthetic nucleosomes: mechanistic insights into the stimulation of Dot1L by ubiquitylated histone H2B. | Q37447402 | ||
| Histone H3K27 trimethylation inhibits H3 binding and function of SET1-like H3K4 methyltransferase complexes | Q37469434 | ||
| Inteins: Nature's Gift to Protein Chemists | Q37630472 | ||
| Chromatin as an expansive canvas for chemical biology | Q37733528 | ||
| Spreading chromatin into chemical biology | Q37829703 | ||
| 9-Fluorenylmethoxycarbonyl-based solid-phase synthesis of peptide α-thioesters | Q37835201 | ||
| Designer proteins: applications of genetic code expansion in cell biology | Q37983986 | ||
| Emerging roles for chromatin as a signal integration and storage platform | Q38092575 | ||
| Readout of epigenetic modifications | Q38103962 | ||
| Using chemistry to investigate the molecular consequences of protein ubiquitylation | Q38224374 | ||
| Novel types and sites of histone modifications emerge as players in the transcriptional regulation contest | Q38249060 | ||
| An efficient Fmoc-SPPS approach for the generation of thioester peptide precursors for use in native chemical ligation | Q38589907 | ||
| Chemical synthesis of peptides and proteins | Q39532197 | ||
| Reciprocal intronic and exonic histone modification regions in humans. | Q39634800 | ||
| Structure of Chromatin | Q39687258 | ||
| A method for genetically installing site-specific acetylation in recombinant histones defines the effects of H3 K56 acetylation | Q40097842 | ||
| Quantitative assessment of protein interaction with methyl-lysine analogues by hybrid computational and experimental approaches | Q40628134 | ||
| Biological Applications of Protein Splicing | Q41230320 | ||
| The site-specific installation of methyl-lysine analogs into recombinant histones | Q41978659 | ||
| Phosphorylation of histone H3(T118) alters nucleosome dynamics and remodeling | Q42230215 | ||
| Understanding the words of chromatin regulation | Q42274324 | ||
| The effects of histone H4 tail acetylations on cation-induced chromatin folding and self-association. | Q42701117 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 265-90 | |
| P577 | publication date | 2015-01-01 | |
| P1433 | published in | Annual Review of Biochemistry | Q567356 |
| P1476 | title | Application of the protein semisynthesis strategy to the generation of modified chromatin | |
| P478 | volume | 84 |
| Q41092167 | 'Traceless' tracing of proteins - high-affinity trans-splicing directed by a minimal interaction pair |
| Q48214971 | 2016 EMBO Chemical Biology Conference |
| Q33817548 | A Chemical Biology Approach to Reveal Sirt6-targeted Histone H3 Sites in Nucleosomes. |
| Q33807310 | A semisynthetic Atg3 reveals that acetylation promotes Atg3 membrane binding and Atg8 lipidation. |
| Q92067494 | Chemical Biology of Autophagy-Related Proteins With Posttranslational Modifications: From Chemical Synthesis to Biological Applications |
| Q37093722 | Chemical Synthesis of Phosphorylated Histone H2A at Tyr57 Reveals Insight into the Inhibition Mode of the SAGA Deubiquitinating Module. |
| Q38700270 | Chemical and semisynthesis of modified histones. |
| Q47810690 | Chemical biology approaches for studying posttranslational modifications |
| Q47101708 | Emerging Chemistry Strategies for Engineering Native Chromatin. |
| Q55379654 | Genetic Code Expansion: A Powerful Tool for Understanding the Physiological Consequences of Oxidative Stress Protein Modifications. |
| Q30390809 | Impaired Chaperone Activity of Human Heat Shock Protein Hsp27 Site-Specifically Modified with Argpyrimidine |
| Q98771711 | Interactions With Histone H3 & Tools to Study Them |
| Q55512348 | Lysine-14 acetylation of histone H3 in chromatin confers resistance to the deacetylase and demethylase activities of an epigenetic silencing complex. |
| Q50494189 | Reading chromatin signatures after DNA double-strand breaks. |
| Q92233232 | Semisynthesis of ubiquitinated histone H2B with a native or nonhydrolyzable linkage |
| Q92003087 | Strategies for Generating Modified Nucleosomes: Applications within Structural Biology Studies |
| Q50861673 | Synthesis of l- and d-Ubiquitin by One-Pot Ligation and Metal-Free Desulfurization. |
| Q28821689 | The Die Is Cast: Precision Electrophilic Modifications Contribute to Cellular Decision Making |
| Q50280774 | Total Chemical Synthesis of Modified Histones |
| Q47693387 | Total chemical synthesis of histones and their analogs, assisted by native chemical ligation and palladium complexes |
| Q48265854 | Utility of the Phenacyl Protecting Group in Traceless Protein Semisynthesis through Ligation-Desulfurization Chemistry. |
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