The leucine zipper domain controls the orientation of AP-1 in the NFAT.AP-1.DNA complex

scientific article published on 01 December 1996

The leucine zipper domain controls the orientation of AP-1 in the NFAT.AP-1.DNA complex is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S1074-5521(96)90165-9
P698PubMed publication ID9000009

P2093author name stringG L Verdine
D A Erlanson
M Chytil
P2860cites workNFATx, a novel member of the nuclear factor of activated T cells family that is expressed predominantly in the thymusQ24316786
Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteinsQ24317724
Cyclic AMP-Independent ATF Family Members Interact with NF-κB and Function in the Activation of the E-Selectin Promoter in Response to CytokinesQ24629510
Characterization of antigen receptor response elements within the interleukin-2 enhancerQ24632042
The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted alpha helices: crystal structure of the protein-DNA complexQ27642986
Crystallographic analysis of the interaction of the glucocorticoid receptor with DNAQ27651364
Crystal structure of an engrailed homeodomain-DNA complex at 2.8 A resolution: a framework for understanding homeodomain-DNA interactionsQ27657540
Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 AQ27660274
Structure of phage 434 Cro protein at 2.35 A resolutionQ27702492
Recognition of a DNA operator by the repressor of phage 434: a view at high resolutionQ27728537
Crystal structure of the heterodimeric bZIP transcription factor c-Fos-c-Jun bound to DNAQ27730317
Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modulesQ27731280
Crystal structure of MyoD bHLH domain-DNA complex: perspectives on DNA recognition and implications for transcriptional activationQ27731319
The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elementsQ27731441
The X-ray structure of the GCN4-bZIP bound to ATF/CREB site DNA shows the complex depends on DNA flexibilityQ27732009
Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domainQ27732150
The leucine zipper: a hypothetical structure common to a new class of DNA binding proteinsQ27860587
NF-AT components define a family of transcription factors targeted in T-cell activationQ28114991
Crystal structure of transcription factor E47: E-box recognition by a basic region helix-loop-helix dimerQ28238671
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexesQ28277749
The role of the leucine zipper in the fos-jun interactionQ28286063
Activation of transcription by two factors that bind promoter and enhancer sequences of the human metallothionein gene and SV40Q28288094
Isolation of the cyclosporin-sensitive T cell transcription factor NFATpQ28511815
NFATc3, a Lymphoid-specific NFATc Family Member That Is Calcium-regulated and Exhibits Distinct DNA Binding SpecificityQ28591436
A self-replicating peptideQ29029830
Transcriptional activation: a complex puzzle with few easy piecesQ29616518
Synthesis of proteins by native chemical ligationQ29616750
The regulation of AP-1 activity by mitogen-activated protein kinasesQ29620431
The c-ets proto-oncogenes encode transcription factors that cooperate with c-Fos and c-Jun for transcriptional activationQ33767307
Design of sequence-specific DNA-binding moleculesQ34038863
Identification of a putative regulator of early T cell activation genesQ34171263
Activation of the granulocyte-macrophage colony-stimulating factor promoter in T cells requires cooperative binding of Elf-1 and AP-1 transcription factorsQ36646025
Functional and physical associations between NF-kappa B and C/EBP family members: a Rel domain-bZIP interactionQ36689762
The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4.Q36804149
Regulatory crosstalk at composite response elementsQ36924778
The NFAT-1 DNA binding complex in activated T cells contains Fra-1 and JunB.Q38321239
Crystal structure of a MAT alpha 2 homeodomain-operator complex suggests a general model for homeodomain-DNA interactionsQ38332701
Fos and Jun: the AP-1 connectionQ39606540
The DNA binding specificity of the basic region of the yeast transcriptional activator GCN4 can be changed by substitution of a single amino acidQ40406808
Signal transmission between the plasma membrane and nucleus of T lymphocytesQ40642986
NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genesQ40693171
Differential activation of c-fos promoter elements by serum, lysophosphatidic acid, G proteins and polypeptide growth factors.Q40789670
Role of kinases and the phosphatase calcineurin in the nuclear shuttling of transcription factor NF-AT4.Q41183095
DNA template and activator-coactivator requirements for transcriptional synergism by Drosophila bicoidQ41259629
Multiple TAFIIs directing synergistic activation of transcriptionQ41259644
Mechanisms of transcriptional synergism between distinct virus-inducible enhancer elementsQ41528186
Site-directed conjugation of nonpeptide groups to peptides and proteins via periodate oxidation of a 2-amino alcohol. Application to modification at N-terminal serineQ43953962
Structural motif of the GCN4 DNA binding domain characterized by affinity cleavingQ44549750
Evidence that a minor groove-binding peptide and a major groove-binding protein can simultaneously occupy a common site on DNAQ44988187
Direct interaction between fos and jun nuclear oncoproteins: role of the 'leucine zipper' domain.Q45933998
Sequence-specific cleavage of double helical DNA by triple helix formation.Q46000915
Transcription factor interactions: selectors of positive or negative regulation from a single DNA element.Q46040111
Importance of minor-groove contacts for recognition of DNA by the binding domain of Hin recombinaseQ46117434
Orientation of the putative recognition helix in the DNA-binding domain of Hin recombinase complexed with the hix siteQ46613256
Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin AQ46979889
Nuclear factor of activated T cells contains Fos and Jun.Q54271859
Structure of the LexA repressor-DNA complex probed by affinity cleavage and affinity photo-cross-linking.Q54590386
Proximity mapping the surface of a membrane protein using an artificial protease: demonstration that the quinone-binding domain of subunit I is near the N-terminal region of subunit II of cytochrome bd.Q54603989
Genetic Approach to Facilitate Purification of Recombinant Proteins with a Novel Metal Chelate AdsorbentQ55934417
Redox regulation of fos and jun DNA-binding activity in vitroQ57963256
Generation of β-globin by sequence-specific proteolysis of a hybrid protein produced in Escherichia coliQ59067885
Incorporation of an EDTA-metal complex at a rationally selected site within a protein: application to EDTA-iron DNA affinity cleaving with catabolite gene activator protein (CAP) and CroQ67505524
Structure of the lambda complex at 2.5 A resolution: details of the repressor-operator interactionsQ67962826
Mapping the structure of a non-native state of staphylococcal nucleaseQ70865556
Only one of the two DNA-bound orientations of AP-1 found in solution cooperates with NFATpQ71798205
Interaction of retinoblastoma gene product with transcription factors ATFa and ATF2Q72325223
Interactions of hydroxyl radicals with tris (hydroxymethyl) aminomethane and Good's buffers containing hydroxymethyl or hydroxyethyl residues produce formaldehydeQ72787473
P433issue12
P304page(s)981-991
P577publication date1996-12-01
P1433published inChemistry and BiologyQ15758410
P1476titleThe leucine zipper domain controls the orientation of AP-1 in the NFAT.AP-1.DNA complex
P478volume3

Reverse relations

cites work (P2860)
Q24634502"Splicing up" drug discovery. Cell-based expression and screening of genetically-encoded libraries of backbone-cyclized polypeptides
Q430578022005 Irving Sigal Young Investigator Award
Q48202682A Facile N-Mercaptoethoxyglycinamide (MEGA) Linker Approach to Peptide Thioesterification and Cyclization
Q42568099A biocompatible condensation reaction for the labeling of terminal cysteine residues on proteins
Q47829676Accessory factor-bZIP-DNA interactions
Q33870964Adding 'splice' to protein engineering
Q24644159Analysis of serotonin N-acetyltransferase regulation in vitro and in live cells using protein semisynthesis
Q28831322Application of the protein semisynthesis strategy to the generation of modified chromatin
Q35893500Biological Activities of Natural and Engineered Cyclotides, a Novel Molecular Scaffold for Peptide-Based Therapeutics
Q41230320Biological Applications of Protein Splicing
Q30862569Biosynthetic phage display: a novel protein engineering tool combining chemical and genetic diversity
Q44632366Cellular stabilization of the melatonin rhythm enzyme induced by nonhydrolyzable phosphonate incorporation.
Q30175897Chemical ligation of folded recombinant proteins: segmental isotopic labeling of domains for NMR studies
Q32031887Chemical protein synthesis
Q73278599Chemical protein synthesis
Q33536606Combinatorial gene regulation by eukaryotic transcription factors
Q36617078Control of interleukin-2 gene transcription: a paradigm for inducible, tissue-specific gene expression
Q35900582Cyclotides, a novel ultrastable polypeptide scaffold for drug discovery
Q30907737Differential gene expression in chemically induced mouse lung adenomas
Q36762983Dual role of the nuclear factor of activated T cells insert region in DNA recognition and cooperative contacts to activator protein 1.
Q35968333Expressed protein ligation using an N-terminal cysteine containing fragment generated in vivo from a pelB fusion protein
Q24657669Expressed protein ligation: a general method for protein engineering
Q30379910Expressed protein ligation: a resourceful tool to study protein structure and function.
Q41475605FIZ1 is expressed during photoreceptor maturation, and synergizes with NRL and CRX at rod-specific promoters in vitro.
Q73711664Generation of a dual-labeled fluorescence biosensor for Crk-II phosphorylation using solid-phase expressed protein ligation
Q51750605High-throughput synthesis of peptide α-thioesters: a safety catch linker approach enabling parallel hydrogen fluoride cleavage.
Q35229609Histones: at the crossroads of peptide and protein chemistry
Q42931157Modular strategy for the semisynthesis of a K+ channel: investigating interactions of the pore helix.
Q91052677Native Chemical Ligation of Peptides and Proteins
Q33722561Peptide ligation and its application to protein engineering
Q33590672Prostaglandin F(2alpha)-F-prostanoid receptor regulates CXCL8 expression in endometrial adenocarcinoma cells via the calcium-calcineurin-NFAT pathway
Q30961015Protein engineering by expressed protein ligation
Q34529929Protein ligation: an enabling technology for the biophysical analysis of proteins
Q34779578Protein phosphorylation by semisynthesis: from paper to practice
Q22252325Protein semisynthesis and expressed protein ligation: chasing a protein's tail
Q30761992Protein synthesis by native chemical ligation: expanded scope by using straightforward methodology
Q34903967Recent advances in the application of expressed protein ligation to protein engineering
Q34313230Segmental isotopic labeling using expressed protein ligation
Q42846179Semisynthesis of cytotoxic proteins using a modified protein splicing element
Q47838742Semisynthesis of proteins using split inteins.
Q77483314Signalling into the T-cell nucleus: NFAT regulation
Q90283052Site-Specific Protein Labeling with N-Hydroxysuccinimide-Esters and the Analysis of Ubiquitin Ligase Mechanisms
Q42265873Site-specific chemical modification of a glycoprotein fragment expressed in yeast
Q44594143Structuring of the 3' splice site by U2AF65.
Q38551464Synthetic approaches to protein phosphorylation.
Q33898249The advantages of ambiguous orientation
Q24620636The chemical biology of protein phosphorylation
Q36729455The orientation of the AP-1 heterodimer on DNA strongly affects transcriptional potency.
Q38307266Virtually unidirectional binding of TBP to the AdMLP TATA box within the quaternary complex with TFIIA and TFIIB.

Search more.