A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus

scientific journal article

A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1027075303
P356DOI10.1038/NG.2796
P3181OpenCitations bibliographic resource ID3702821
P932PMC publication ID3840115
P698PubMed publication ID24121790
P5875ResearchGate publication ID257754495

P50authorCarlos CaldasQ9696930
Leslie BernsteinQ60607806
Paul D P PharoahQ61822938
Xinxue LiuQ64481663
Nicholas J. ShaheenQ64749672
Anna H WuQ89864403
Harvey A. RischQ97531829
Marilie GammonQ104751082
Douglas A. CorleyQ110251065
Olof NyrénQ114237293
Stephen ChanockQ27662321
David C. WhitemanQ37837275
Stuart MacgregorQ42711014
Geoffrey LiuQ51134597
P2093author name stringThomas L. Vaughan
Rui Zhang
Rebecca C. Fitzgerald
Wong-Ho Chow
Weimin Ye
Nicholas K. Hayward
Patricia Harrington
Lynn Onstad
Irene Debiram-Beecham
Pierre Lao-Sirieix
Yvonne Romero
David M. Levine
Brian J. Reid
Alan G. Casson
Cassandra Sather
Isabel Caldas
Laura J. Hardie
Liam J. Murray
Nigel C. Bird
Weronica E. Ek
P2860cites workAn integrated encyclopedia of DNA elements in the human genomeQ22122150
A family history of Barrett's oesophagus: Another risk factor?Q58104647
Functional single-nucleotide polymorphism of epidermal growth factor is associated with the development of Barrett's esophagus and esophageal adenocarcinomaQ58376620
Familial Barrett's esophagus associated with adenocarcinomaQ68079125
Carcinoma arising in familial Barrett's esophagusQ71500732
Familial aggregation of gastroesophageal reflux in patients with Barrett's esophagus and esophageal adenocarcinomaQ73835483
Familial clustering of reflux symptomsQ77424138
Identification of Barrett's esophagus in relatives by endoscopic screeningQ81036244
Familial Barrett's adenocarcinomaQ82853387
Familial gastroesophageal reflux and development of Barrett's esophagusQ93566136
MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypesQ24635938
Genes mirror geography within EuropeQ24644872
PLINK: a tool set for whole-genome association and population-based linkage analysesQ24677407
Principal components analysis corrects for stratification in genome-wide association studiesQ27860975
Foxp2 and Foxp1 cooperatively regulate lung and esophagus developmentQ28508512
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.Q29417009
Genome-wide association study identifies novel loci predisposing to cutaneous melanomaQ29417131
METAL: fast and efficient meta-analysis of genomewide association scansQ29547217
Transcriptome genetics using second generation sequencing in a Caucasian populationQ29614413
Annotation of functional variation in personal genomes using RegulomeDBQ29614867
The Creb1 coactivator Crtc1 is required for energy balance and fertilityQ30439853
Quality control and quality assurance in genotypic data for genome-wide association studiesQ30498925
A high-performance computing toolset for relatedness and principal component analysis of SNP dataQ30573123
Barx1-mediated inhibition of Wnt signaling in the mouse thoracic foregut controls tracheo-esophageal septation and epithelial differentiationQ31028060
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studiesQ34151528
Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagusQ34298428
GWASTools: an R/Bioconductor package for quality control and analysis of genome-wide association studiesQ34439401
Iodine in evolution of salivary glands and in oral healthQ35008249
High-resolution genomic profiling of chromosomal aberrations using Infinium whole-genome genotypingQ35012994
High frequency of PIK3R1 and PIK3R2 mutations in endometrial cancer elucidates a novel mechanism for regulation of PTEN protein stabilityQ35275603
p85β phosphoinositide 3-kinase subunit regulates tumor progressionQ36094306
Complex diseases in gastroenterology and hepatology: GERD, Barrett's, and esophageal adenocarcinomaQ36160959
FOXP1: a potential therapeutic target in cancer.Q36871999
A functional epidermal growth factor (EGF) polymorphism, EGF serum levels, and esophageal adenocarcinoma risk and outcomeQ36948334
Altered LKB1/CREB-regulated transcription co-activator (CRTC) signaling axis promotes esophageal cancer cell migration and invasion.Q39517661
Expression of epidermal growth factor, transforming growth factor alpha and their receptor in gastro-oesophageal diseasesQ40881497
Barrett associated MHC and FOXF1 variants also increase esophageal carcinoma riskQ44265917
P4510describes a project that usesgenome-wide association studyQ1098876
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectadenocarcinomaQ356033
Barrett's esophagusQ808892
genome-wide association studyQ1098876
susceptibility locusQ62091149
P304page(s)1487–1493
P577publication date2013-12-01
P1433published inNature GeneticsQ976454
P1476titleA genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus
P478volume45

Reverse relations

cites work (P2860)
Q34744122A genome wide meta-analysis study for identification of common variation associated with breast cancer prognosis
Q39531221A meta-analysis of reflux genome-wide association studies in 6750 Northern Europeans from the general population
Q36753025A newly identified susceptibility locus near FOXP1 modifies the association of gastroesophageal reflux with Barrett's esophagus
Q38368081A review of the epidemiology of Barrett's oesophagus and oesophageal adenocarcinoma
Q40365358ACG Clinical Guideline: Diagnosis and Management of Barrett's Esophagus
Q91517636Adaptive Transcriptional Responses by CRTC Coactivators in Cancer
Q50209263An APOE-independent cis-eSNP on chromosome 19q13.32 influences tau levels and late-onset Alzheimer's disease risk.
Q36551207Analyzing the Association of Polymorphisms in the CRYBB2 Gene with Prostate Cancer Risk in African Americans
Q36029469Assessment of Esophageal Adenocarcinoma Risk Using Somatic Chromosome Alterations in Longitudinal Samples in Barrett's Esophagus
Q41652261Association Between Germline Mutation in VSIG10L and Familial Barrett Neoplasia
Q54232649Barrett's Esophagus and Esophageal Adenocarcinoma: How Common Are They Really?
Q33959620Barrett's esophagus and cancer risk: how research advances can impact clinical practice
Q38363283Barrett's esophagus: recent insights into pathogenesis and cellular ontogeny.
Q38575013Biomarkers and novel agents in esophago-gastric cancer: are we making progress?
Q38213141Biomarkers for dysplastic Barrett's: ready for prime time?
Q88528269Biomarkers of Barrett's Esophagus: From the Laboratory to Clinical Practice
Q91891617Centromeric Satellite DNAs: Hidden Sequence Variation in the Human Population
Q36551285Chronic gastroesophageal reflux disease shares genetic background with esophageal adenocarcinoma and Barrett's esophagus
Q38940534Common Variants Confer Susceptibility to Barrett's Esophagus: Insights from the First Genome-Wide Association Studies
Q35144975Comparative analyses of lung transcriptomes in patients with alveolar capillary dysplasia with misalignment of pulmonary veins and in foxf1 heterozygous knockout mice
Q38815316Computation of ancestry scores with mixed families and unrelated individuals
Q37153044Constrained Score Statistics Identify Genetic Variants Interacting with Multiple Risk Factors in Barrett's Esophagus
Q37536975Convergent evidence from systematic analysis of GWAS revealed genetic basis of esophageal cancer
Q55007510Correlation between prostate stem cell antigen gene expression and oral squamous cell carcinoma.
Q64118172Cumulative evidence for association between genetic polymorphisms and esophageal cancer susceptibility: A review with evidence from meta-analysis and genome-wide association studies
Q91474078DNA methylation changes in infants between 6 and 52 weeks
Q39212995Deregulation of CRTCs in Aging and Age-Related Disease Risk
Q89896747Detection of LINE-1 hypomethylation in cfDNA of Esophageal Adenocarcinoma Patients
Q47726498Detection of genetic alterations in cfDNA as a possible strategy to monitor the neoplastic progression of Barrett's esophagus
Q47298550Determining Risk of Barrett's Esophagus and Esophageal Adenocarcinoma Based on Epidemiologic Factors and Genetic Variants
Q38310617Diagnostic and Management Implications of Basic Science Advances in Barrett's Esophagus
Q28079946Endoscopic risk factors for neoplastic progression in patients with Barrett's oesophagus
Q57433696Environmentally Induced Alterations in the Epigenome Affecting Obesity and Cancer in Minority Populations
Q26852690Epidemiological studies of esophageal cancer in the era of genome-wide association studies
Q35893814Epidemiology, Diagnosis, and Management of Esophageal Adenocarcinoma
Q42131289Esophageal Cancer: Genomic and Molecular Characterization, Stem Cell Compartment and Clonal Evolution
Q38734003Esophageal Cancer: New Insights into a Heterogenous Disease
Q26799758Esophageal cancer: Risk factors, screening and endoscopic treatment in Western and Eastern countries
Q38542183Esophageal development and epithelial homeostasis
Q28077495Etiology and Prevention of Esophageal Cancer
Q31028176Fitting Proportional Odds Model to Case-Control data with Incorporating Hardy-Weinberg Equilibrium
Q90133777Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases
Q90701991Gastrointestinal dysfunction in autism displayed by altered motility and achalasia in Foxp1 +/- mice
Q36109030Genetic Insights in Barrett's Esophagus and Esophageal Adenocarcinoma
Q26740556Genetic susceptibility to Barrett's oesophagus: Lessons from early studies
Q47366887Genetic variants in miR-196a2 and miR-499 are associated with susceptibility to esophageal squamous cell carcinoma in Chinese Han population
Q88391279Genetic variants of FOXP1 and FOXF1 are associated with the susceptibility of oesophageal adenocarcinoma in Chinese population
Q34479395Genetics and early detection in idiopathic pulmonary fibrosis
Q34537405Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis
Q38668307Genome-wide association studies of cancer in diverse populations
Q37191879Genome-wide association study identifies 14 novel risk alleles associated with basal cell carcinoma
Q41826361Genomic and Epigenetic Complexity of the FOXF1 Locus in 16q24.1: Implications for Development and Disease.
Q39530717Germline variation in inflammation-related pathways and risk of Barrett's oesophagus and oesophageal adenocarcinoma
Q92350925Identification of loci of functional relevance to Barrett's esophagus and esophageal adenocarcinoma: Cross-referencing of expression quantitative trait loci data from disease-relevant tissues with genetic association data
Q38831897In silico dissection of miRNA targetome polymorphisms and their role in regulating miRNA-mediated gene expression in esophageal cancer.
Q89845986Increased prevalence of Barrett's esophagus in patients with MUTYH-associated polyposis (MAP)
Q34586242Integrative post-genome-wide association analysis of CDKN2A and TP53 SNPs and risk of esophageal adenocarcinoma
Q52649946Interactions Between Genetic Variants and Environmental Factors Affect Risk of Esophageal Adenocarcinoma and Barrett's Esophagus.
Q88132507Leaky transporters and sphincters in Barrett's oesophagus?
Q48529215Letter: future directions for epidemiological studies of Barrett's oesophagus
Q40056604Methodological quality evaluation of systematic reviews or meta-analyses on ERCC1 in non-small cell lung cancer: a systematic review
Q35651285MiRNA-Related SNPs and Risk of Esophageal Adenocarcinoma and Barrett's Esophagus: Post Genome-Wide Association Analysis in the BEACON Consortium
Q35486982Molecular and clinical analyses of 16q24.1 duplications involving FOXF1 identify an evolutionarily unstable large minisatellite
Q34508850Molecular markers and imaging tools to identify malignant potential in Barrett's esophagus
Q64458449No Association Between Vitamin D Status and Risk of Barrett's Esophagus or Esophageal Adenocarcinoma: A Mendelian Randomization Study
Q34354158Obesity and risk of esophageal adenocarcinoma and Barrett's esophagus: a Mendelian randomization study
Q39205170Obesity-associated digestive cancers: A review of mechanisms and interventions
Q38816897Oesophageal adenocarcinoma and gastric cancer: should we mind the gap?
Q37720195Pathway‑based detection of idiopathic pulmonary fibrosis at an early stage
Q36290025Pleiotropic analysis of cancer risk loci on esophageal adenocarcinoma risk
Q64926353Polymorphism of miRNA and esophageal cancer risk: an updated systemic review and meta-analysis.
Q33361584Polymorphisms in Genes of Relevance for Oestrogen and Oxytocin Pathways and Risk of Barrett's Oesophagus and Oesophageal Adenocarcinoma: A Pooled Analysis from the BEACON Consortium
Q36470039Polymorphisms in genes in the androgen pathway and risk of Barrett's esophagus and esophageal adenocarcinoma
Q35042479Polymorphisms near TBX5 and GDF7 are associated with increased risk for Barrett's esophagus
Q91711671Polymorphisms of the BARX1 and ADAMTS17 Locus Genes in Individuals With Gastroesophageal Reflux Disease
Q47901698Polymorphisms of the FOXF1 and MHC locus genes in individuals undergoing esophageal acid reflux assessments
Q38857539Precancer Atlas to Drive Precision Prevention Trials.
Q35243217Precision prevention of oesophageal adenocarcinoma
Q46923415Prognostic impact of FOXF1 polymorphisms in gastric cancer patients
Q40083252Racial Disparity in Gastrointestinal Cancer Risk
Q26864783Recent developments in pathogenesis, diagnosis and therapy of Barrett's esophagus
Q28076807Risk Factors for Barrett's Oesophagus
Q40879184Risk factors for Barrett's esophagus
Q34036491Risk of esophageal adenocarcinoma decreases with height, based on consortium analysis and confirmed by Mendelian randomization
Q34736608Role of LKB1-CRTC1 on glycosylated COX-2 and response to COX-2 inhibition in lung cancer.
Q28080445Screening for Barrett's Esophagus
Q41660792Single nucleotide polymorphisms in CRTC1 and BARX1 are associated with esophageal adenocarcinoma
Q51048878Strategy for prevention of cancers of the esophagus.
Q36358569Supportive evidence for FOXP1, BARX1, and FOXF1 as genetic risk loci for the development of esophageal adenocarcinoma
Q36895095The Barrett-associated variants at GDF7 and TBX5 also increase esophageal adenocarcinoma risk
Q39440077The Evolving Genomic Landscape of Barrett's Esophagus and Esophageal Adenocarcinoma
Q38771931The Genetics of Barrett's Esophagus: A Familial and Population-Based Perspective
Q35815874The Role of Gastroesophageal Reflux and Other Factors during Progression to Esophageal Adenocarcinoma
Q37227732The characterization of an intestine-like genomic signature maintained during Barrett's-associated adenocarcinogenesis reveals an NR5A2-mediated promotion of cancer cell survival.
Q54318784Translational research on Barrett's esophagus.
Q33714435Trends in esophageal and esophagogastric junction cancer research from 2007 to 2016: A bibliometric analysis
Q39836449Variants of EVER1 and EVER2 (TMC6 and TMC8) and human papillomavirus status in patients with mucosal squamous cell carcinoma of the head and neck
Q28602015ZYG11A serves as an oncogene in non-small cell lung cancer and influences CCNE1 expression

Search more.