Detection of LINE-1 hypomethylation in cfDNA of Esophageal Adenocarcinoma Patients

scientific article published on 24 February 2020

Detection of LINE-1 hypomethylation in cfDNA of Esophageal Adenocarcinoma Patients is …
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scholarly articleQ13442814

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P356DOI10.3390/IJMS21041547
P932PMC publication ID7073170
P698PubMed publication ID32102481

P50authorElisa BoldrinQ55755026
Rita AlfieriQ55755145
P2093author name stringMatteo Fassan
Daniela Saggioro
Matteo Curtarello
Stefano Realdon
Marco Dallan
P2860cites workPerioperative chemo(radio)therapy versus primary surgery for resectable adenocarcinoma of the stomach, gastroesophageal junction, and lower esophagusQ24202957
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Reprimo methylation is a potential biomarker of Barrett's-Associated esophageal neoplastic progressionQ28275200
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Prognostic significance of LINE-1 hypomethylation in oropharyngeal squamous cell carcinoma.Q33742722
DNA hypomethylation in cancer cellsQ33862334
Meta-analysis of postoperative efficacy in patients receiving chemoradiotherapy followed by surgery for resectable esophageal carcinomaQ34469077
Hypermethylation of the nel-like 1 gene is a common and early event and is associated with poor prognosis in early-stage esophageal adenocarcinomaQ34621907
How to interpret methylation sensitive amplified polymorphism (MSAP) profiles?Q35083941
Long interspersed nuclear element-1 hypomethylation in cancer: biology and clinical applicationsQ36001900
Liquid biopsy as a novel tool to monitor the carcinogenesis of Barrett's esophagus.Q53090492
Preoperative Chemoradiotherapy for Esophageal or Junctional CancerQ57259796
Methylation of LINE-1 in cell-free DNA serves as a liquid biopsy biomarker for human breast cancers and dog mammary tumorsQ60907663
Detailed methylation map of LINE-1 5'-promoter region reveals hypomethylated CpG hotspots associated with tumor tissue specificityQ64069858
Evaluation of a quantitative DNA methylation analysis technique using methylation-sensitive/dependent restriction enzymes and real-time PCRQ81509951
Pyrosequencing assay to measure LINE-1 methylation level in esophageal squamous cell carcinomaQ83081238
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Elevated expression of MDR1 associated with Line-1 hypomethylation in esophageal squamous cell carcinomaQ36464436
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Epigenetic alterations and their clinical implications in esophageal squamous cell carcinomaQ38093059
A global assessment of the oesophageal adenocarcinoma epidemicQ38430776
LINE-1 in cancer: multifaceted functions and potential clinical implicationsQ38579541
Cell-free DNA: Preanalytical variablesQ38581212
LINE-1 hypomethylation is associated to specific clinico-pathological features in Stage I non-small cell lung cancerQ38720437
LINE-1 hypomethylation, DNA copy number alterations, and CDK6 amplification in esophageal squamous cell carcinomaQ39034520
Integrated genomic characterization of oesophageal carcinomaQ39041152
Oncogenic roles of DNA hypomethylation through the activation of cancer-germline genesQ39200638
Does the Incidence of Adenocarcinoma of the Esophagus and Gastric Cardia Continue to Rise in the Twenty-First Century?-a SEER Database Analysis.Q44512499
Prognostic importance of promoter hypermethylation of multiple genes in esophageal adenocarcinomaQ44587417
LINE-1 hypomethylation is associated with a poor prognosis among patients with curatively resected esophageal squamous cell carcinomaQ45166931
Hypermethylated APC DNA in plasma and prognosis of patients with esophageal adenocarcinomaQ46062133
Epigenetic patterns in the progression of esophageal adenocarcinomaQ46291635
Identifying DNA methylation biomarkers for non-endoscopic detection of Barrett's esophagusQ47561735
Detection of genetic alterations in cfDNA as a possible strategy to monitor the neoplastic progression of Barrett's esophagusQ47726498
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue4
P577publication date2020-02-24
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleDetection of LINE-1 hypomethylation in cfDNA of Esophageal Adenocarcinoma Patients
P478volume21