Dopaminergic augmentation of delta-9-tetrahydrocannabinol (THC) discrimination: possible involvement of D2-induced formation of anandamide

scientific article (publication date: 24 February 2010)

Dopaminergic augmentation of delta-9-tetrahydrocannabinol (THC) discrimination: possible involvement of D2-induced formation of anandamide is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1023700865
P356DOI10.1007/S00213-010-1789-8
P932PMC publication ID2834964
P698PubMed publication ID20179908
P5875ResearchGate publication ID41548959

P2093author name stringGoldberg SR
Solinas M
Tanda G
Wertheim CE
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The endocannabinoid system in the basal ganglia and in the mesolimbic reward system: implications for neurological and psychiatric disordersQ35586641
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Discriminative stimulus functions in rats of AM1346, a high-affinity CB1R selective anandamide analogQ37055254
Inhibition of anandamide hydrolysis by cyclohexyl carbamic acid 3'-carbamoyl-3-yl ester (URB597) reverses abuse-related behavioral and neurochemical effects of nicotine in ratsQ37146387
Fatty acid amide hydrolase inhibition heightens anandamide signaling without producing reinforcing effects in primatesQ37239653
Substitution profile of Delta9-tetrahydrocannabinol, triazolam, hydromorphone, and methylphenidate in humans discriminating Delta9-tetrahydrocannabinolQ37266063
Strain-specific facilitation of dopamine efflux by Δ9-tetrahydrocannabinol in the nucleus accumbens of rat: An in vivo microdialysis studyQ41130886
Dopamine activation of endogenous cannabinoid signaling in dorsal striatumQ41646203
Role of dynorphin and enkephalin in the regulation of striatal output pathways and behaviorQ42464704
Anatomical and physiological evidence for D1 and D2 dopamine receptor colocalization in neostriatal neuronsQ42484453
Endocannabinoid-mediated rescue of striatal LTD and motor deficits in Parkinson's disease modelsQ42508054
A cannabinoid mechanism in relapse to cocaine seeking.Q43759232
Inhibition of methamphetamine self-administration in rats by cannabinoid receptor antagonist AM 251.Q44048463
delta9-Tetrahydrocannabinol excites rat VTA dopamine neurons through activation of cannabinoid CB1 but not opioid receptorsQ44345904
Cannabinoid and heroin activation of mesolimbic dopamine transmission by a common mu1 opioid receptor mechanismQ44346123
Involvement of mu-, delta- and kappa-opioid receptor subtypes in the discriminative-stimulus effects of delta-9-tetrahydrocannabinol (THC) in ratsQ44347637
A critical interaction between dopamine D2 receptors and endocannabinoids mediates the effects of cocaine on striatal gabaergic TransmissionQ44853701
Beta-endorphin elevations in the ventral tegmental area regulate the discriminative effects of Delta-9-tetrahydrocannabinol.Q44951522
Lack of CB1 cannabinoid receptor impairs cocaine self-administration.Q45292739
Nicotinic facilitation of delta9-tetrahydrocannabinol discrimination involves endogenous anandamideQ48247701
Cannabinoid transmission and reward-related eventsQ48285165
The endogenous cannabinoid anandamide produces delta-9-tetrahydrocannabinol-like discriminative and neurochemical effects that are enhanced by inhibition of fatty acid amide hydrolase but not by inhibition of anandamide transportQ48315882
Increase in meso-prefrontal dopaminergic activity after stimulation of CB1 receptors by cannabinoidsQ48383234
Anandamide administration alone and after inhibition of fatty acid amide hydrolase (FAAH) increases dopamine levels in the nucleus accumbens shell in ratsQ48485540
Two brain sites for cannabinoid reward.Q48556363
Using drug-discrimination techniques to study the abuse-related effects of psychoactive drugs in ratsQ48608961
The role of dopamine receptor subtypes in the discriminative stimulus effects of amphetamine and cocaine in rats.Q51550730
Discriminative Stimulus Properties of Δ9-Tetrahydrocannabinol: Mechanistic StudiesQ52292952
Phenotypical characterization of the neurons expressing the D1 and D2 dopamine receptors in the monkey striatumQ64789945
The cannabinoid CB1 antagonist N-piperidinyl-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl) -4-methylpyrazole-3-carboxamide (SR-141716A) differentially alters the reinforcing effects of heroin under continuous reinforcement, fixed ratio, and progressiveQ73180328
P433issue2
P921main subjectdopamineQ170304
tetrahydrocannabinolQ190067
anandamideQ410228
cannabinoidsQ422936
P304page(s)191-202
P577publication date2010-02-24
P1433published inPsychopharmacologyQ1422802
P1476titleDopaminergic augmentation of delta-9-tetrahydrocannabinol (THC) discrimination: possible involvement of D2-induced formation of anandamide
P478volume209

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Q90524726Brain activity of anandamide: a rewarding bliss?
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