In vitro generation of human pluripotent stem cell derived lung organoids

scientific article (publication date: 24 March 2015)

In vitro generation of human pluripotent stem cell derived lung organoids is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.7554/ELIFE.05098
P3181OpenCitations bibliographic resource ID2128432
P932PMC publication ID4370217
P698PubMed publication ID25803487

P50authorEric S. WhiteQ38324814
Ophir D KleinQ42318176
David R HillQ82080349
P2093author name stringJason R Spence
Christopher N Mayhew
James M Wells
Gail H Deutsch
Yu-Hwai Tsai
Roy Nattiv
Briana R Dye
Michael A H Ferguson
Melinda S Nagy
Rachel Dyal
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Branching of lung epithelium in vitro occurs in the absence of endothelial cellsQ41592616
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Directed differentiation of human pluripotent stem cells into intestinal tissue in vitroQ41770080
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The Id2+ distal tip lung epithelium contains individual multipotent embryonic progenitor cellsQ42135800
Number and proliferation of basal and parabasal cells in normal human airway epithelium.Q42456416
Immunohistochemical and ultrastructural studies of basal cells, Clara cells and bronchiolar cuboidal cells in normal human airwaysQ42467680
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Vascularized and functional human liver from an iPSC-derived organ bud transplantQ48453997
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Control of basement membrane remodeling and epithelial branching morphogenesis in embryonic lung by Rho and cytoskeletal tension.Q52561854
Lamellar body formation in normal and surfactant protein B-deficient fetal miceQ73614064
Bmp4 and Fgf10 play opposing roles during lung bud morphogenesisQ73815422
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Generation of multiciliated cells in functional airway epithelia from human induced pluripotent stem cellsQ33674499
Efficient endoderm induction from human pluripotent stem cells by logically directing signals controlling lineage bifurcations.Q33711163
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Signaling through BMP receptors promotes respiratory identity in the foregut via repression of Sox2.Q33818155
Generation of multipotent lung and airway progenitors from mouse ESCs and patient-specific cystic fibrosis iPSCsQ34031395
Human iPS cell-derived alveolar epithelium repopulates lung extracellular matrix.Q34038571
Efficient generation of lung and airway epithelial cells from human pluripotent stem cellsQ34039177
Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seqQ34094294
Airway branching morphogenesis in three dimensional cultureQ34151870
Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cellsQ34157222
Cellular and molecular characteristics of basal cells in airway epitheliumQ34323743
De novo formation of insulin-producing "neo-β cell islets" from intestinal cryptsQ34409239
Decreased lung fibroblast growth factor 18 and elastin in human congenital diaphragmatic hernia and animal modelsQ34575666
Airway branching has conserved needs for local parasympathetic innervation but not neurotransmission.Q34630075
Self-formation of optic cups and storable stratified neural retina from human ESCs.Q34639338
Gene regulatory networks governing lung specificationQ34678933
Biogenesis of lamellar bodies, lysosome-related organelles involved in storage and secretion of pulmonary surfactantQ34874707
HNF4A is essential for specification of hepatic progenitors from human pluripotent stem cellsQ35208702
An in vivo model of human small intestine using pluripotent stem cellsQ35533803
Directing lung endoderm differentiation in pluripotent stem cellsQ36004884
Optic vesicle-like structures derived from human pluripotent stem cells facilitate a customized approach to retinal disease treatment.Q36143248
Dynamic regulation of platelet-derived growth factor receptor α expression in alveolar fibroblasts during realveolarizationQ36369940
Acellular normal and fibrotic human lung matrices as a culture system for in vitro investigationQ36488760
Conditional gene inactivation reveals roles for Fgf10 and Fgfr2 in establishing a normal pattern of epithelial branching in the mouse lung.Q36511680
Generation of anterior foregut endoderm from human embryonic and induced pluripotent stem cells.Q36901227
Structure and function of lamellar bodies, lipid-protein complexes involved in storage and secretion of cellular lipidsQ36989789
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Generating human intestinal tissue from pluripotent stem cells in vitroQ37495400
Differentiated human stem cells resemble fetal, not adult, β cellsQ37612773
Extracellular matrix and cytoskeletal dynamics during branching morphogenesis.Q38011553
P4510describes a project that usesggplot2Q326489
ImageJQ1659584
P407language of work or nameEnglishQ1860
P921main subjectpluripotencyQ1894941
organoidQ11293125
P577publication date2015-03-24
P1433published ineLifeQ2000008
P1476titleIn vitro generation of human pluripotent stem cell derived lung organoids
P478volume4

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