Humans in a Dish: The Potential of Organoids in Modeling Immunity and Infectious Diseases

scientific article published on 5 December 2017

Humans in a Dish: The Potential of Organoids in Modeling Immunity and Infectious Diseases is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3389/FMICB.2017.02402
P932PMC publication ID5723307
P698PubMed publication ID29259597

P2093author name stringPeter J Peters
Nino Iakobachvili
P2860cites workZika virus. I. Isolations and serological specificityQ22240545
Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV ExposureQ24004552
Zika virus impairs growth in human neurospheres and brain organoidsQ24083091
Zika Virus Depletes Neural Progenitors in Human Cerebral Organoids through Activation of the Innate Immune Receptor TLR3Q24261340
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Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell- and patient-derived tumor organoidsQ27314878
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Co-culture with intestinal epithelial organoids allows efficient expansion and motility analysis of intraepithelial lymphocytesQ27320091
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Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal nicheQ28239639
Salmonella Manipulation of Host Signaling Pathways Provokes Cellular Transformation Associated with Gallbladder CarcinomaQ28262657
A functional CFTR assay using primary cystic fibrosis intestinal organoidsQ28291898
Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axisQ28298678
Recent Zika Virus Isolates Induce Premature Differentiation of Neural Progenitors in Human Brain OrganoidsQ28578660
Bending gradients: how the intestinal stem cell gets its homeQ28648436
Autosomal recessive primary microcephaly (MCPH): a review of clinical, molecular, and evolutionary findingsQ28769509
Cerebral organoids model human brain development and microcephalyQ28973619
In vitro generation of human pluripotent stem cell derived lung organoidsQ28973622
Self-organizing optic-cup morphogenesis in three-dimensional cultureQ29616181
Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitroQ29616198
Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cellsQ33289420
Metastatic tumor evolution and organoid modeling implicate TGFBR2 as a cancer driver in diffuse gastric cancerQ34091425
Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasitesQ34508838
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Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesisQ34673674
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Human iPS cell-derived insulin producing cells form vascularized organoids under the kidney capsules of diabetic miceQ35550611
Stem cell-derived human intestinal organoids as an infection model for rotavirusesQ36099785
Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastasesQ36238283
The Bial 10-2474 Phase 1 Study-A Drug Development Perspective and Recommendations for Future First-in-Human TrialsQ36339579
Intestinal organoids model human responses to infection by commensal and Shiga toxin producing Escherichia coliQ36405482
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In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration.Q36791239
Niche-independent high-purity cultures of Lgr5+ intestinal stem cells and their progenyQ37633867
Studying the mononuclear phagocyte system in the molecular age.Q37949247
Stem cell-derived cell cultures and organoids for protozoan parasite propagation and studying host-parasite interactionQ38035139
Growing self-organizing mini-guts from a single intestinal stem cell: mechanism and applicationsQ38112669
Adult intestinal stem cells: critical drivers of epithelial homeostasis and regenerationQ38170259
Development and function of dendritic cell subsetsQ38212449
"RAF" neighborhood: protein-protein interaction in the Raf/Mek/Erk pathwayQ38220879
Personalized Proteome Profiles of Healthy and Tumor Human Colon Organoids Reveal Both Individual Diversity and Basic Features of Colorectal CancerQ38774913
Prospective derivation of a living organoid biobank of colorectal cancer patients.Q38877277
Retinal Organoids from Pluripotent Stem Cells Efficiently Recapitulate Retinogenesis.Q38884982
ESX-1-mediated translocation to the cytosol controls virulence of mycobacteriaQ39360723
Parsing clinical success ratesQ39644900
Modelling human development and disease in pluripotent stem-cell-derived gastric organoidsQ41680408
Directed differentiation of human pluripotent stem cells into intestinal tissue in vitroQ41770080
Long-term, hormone-responsive organoid cultures of human endometrium in a chemically defined mediumQ41966840
Establishment of a novel lingual organoid culture system: generation of organoids having mature keratinized epithelium from adult epithelial stem cellsQ42088935
Vascularized and functional human liver from an iPSC-derived organ bud transplantQ48453997
Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5⁺ stem cell.Q50501047
Designer matrices for intestinal stem cell and organoid culture.Q51099747
Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids.Q52423411
M. tuberculosis and M. leprae Translocate from the Phagolysosome to the Cytosol in Myeloid CellsQ59498046
Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's EpitheliumQ63406947
P921main subjectorganoidQ11293125
P304page(s)2402
P577publication date2017-12-05
P1433published inFrontiers in MicrobiologyQ27723481
P1476titleHumans in a Dish: The Potential of Organoids in Modeling Immunity and Infectious Diseases
P478volume8

Reverse relations

cites work (P2860)
Q64969344Host-pathogen interactions in typhoid fever: the model is the message.
Q58565205In vitro and ex vivo systems at the forefront of infection modeling and drug discovery
Q99711261New Insights and Current Approaches in Cardiac Hypertrophy Cell Culture, Tissue Engineering Models, and Novel Pathways Involving Non-Coding RNA
Q90406871Norovirus Replication in Human Intestinal Epithelial Cells Is Restricted by the Interferon-Induced JAK/STAT Signaling Pathway and RNA Polymerase II-Mediated Transcriptional Responses
Q90382905Opinion: Are Organoids the End of Model Evolution for Studying Host Intestinal Epithelium/Microbe Interactions?
Q59813480Pathogenesis of and the Host Defense in Ascending Infections of Human Fallopian Tube
Q57027796Polarized Entry of Human Parechoviruses in the Airway Epithelium

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