Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet

scientific article (publication date: 30 October 2009)

Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1182/BLOOD-2009-07-235358
P3181OpenCitations bibliographic resource ID455084
P698PubMed publication ID19880497
P5875ResearchGate publication ID38058746

P50authorClara D. BloomfieldQ4793409
Pierre FenauxQ30170095
Richard A. LarsonQ41899936
Miguel A SanzQ54544774
Sergio AmadoriQ56724874
Hartmut DöhnerQ66385451
Frederick R. AppelbaumQ75025725
Dietger NiederwieserQ88402151
Elihu EsteyQ96145785
P2093author name stringBob Löwenberg
Martin S Tallman
David Grimwade
Alan K Burnett
Tomoki Naoe
Hervé Dombret
Gert J Ossenkoppele
Francesco Lo-Coco
European LeukemiaNet
Thomas Büchner
Jorge Sierra
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
diagnosisQ16644043
acute myeloid leukemiaQ264118
P304page(s)453-474
P577publication date2009-10-30
P1433published inBloodQ885070
P1476titleDiagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet
P478volume115

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Q50859525Changes in cytogenetics and molecular genetics in acute myeloid leukemia from childhood to adult age groups.
Q45332610Characteristics and clinical significance of cytogenetic abnormalities in polycythemia vera
Q41476969Characteristics and outcome of therapy-related myeloid neoplasms: Report from the Italian network on secondary leukemias
Q48305735Characteristics and outcomes of older patients with secondary acute myeloid leukemia according to treatment approach.
Q41928869Characteristics of De Novo Acute Myeloid Leukemia Patients in Palestine: Experience of An-Najah National University Hospital
Q51033194Characterization and analysis of the outcome of adults with acute myeloid leukemia treated in a Brazilian University hospital over three decades.
Q59194228Characterization and prognostic significance of mitochondrial DNA variations in acute myeloid leukemia
Q98725872Characterization of FLT3-ITDmut acute myeloid leukemia: molecular profiling of leukemic precursor cells
Q55025524Characterization of NPM1, FLT3, and IDH1 mutations in adult patients with acute myeloid leukemia: a Brazilian cohort study.
Q36715925Characterization of gene mutations and copy number changes in acute myeloid leukemia using a rapid target enrichment protocol
Q38747513Characterization of hsa_circ_0004277 as a New Biomarker for Acute Myeloid Leukemia via Circular RNA Profile and Bioinformatics Analysis
Q45250906Chemomodulation of sequential high-dose cytarabine by fludarabine in relapsed or refractory acute myeloid leukemia: a randomized trial of the AMLCG.
Q64245424Chimeric Antigen Receptor (CAR) T Cell Therapy in Acute Myeloid Leukemia (AML)
Q38044772Chromosomal aberrations and fusion genes in myeloid malignancies
Q33822055Chromosome abnormalities at onset of complete remission are associated with worse outcome in patients with acute myeloid leukemia and an abnormal karyotype at diagnosis: CALGB 8461 (Alliance).
Q49989317Classification and risk assessment in AML: integrating cytogenetics and molecular profiling.
Q33781150Clearance of acute myeloid leukemia by haploidentical natural killer cells is improved using IL-2 diphtheria toxin fusion protein
Q47128524Clinical Assessment and Diagnosis of Germline Predisposition to Hematopoietic Malignancies: The University of Chicago Experience
Q49338306Clinical Features and Outcomes of 666 Cases with Therapy-Related Myelodysplastic Syndrome (t-MDS).
Q38831810Clinical Outcomes of 217 Patients with Acute Erythroleukemia According to Treatment Type and Line: A Retrospective Multinational Study.
Q38904250Clinical Relevance of RUNX1 and CBFB Alterations in Acute Myeloid Leukemia and Other Hematological Disorders
Q89994575Clinical Significance of ABCB1 in Acute Myeloid Leukemia: A Comprehensive Study
Q42705413Clinical Utility of Next-Generation Sequencing for Oncogenic Mutations in Patients with Acute Myeloid Leukemia Undergoing Allogeneic Stem Cell Transplantation.
Q53308704Clinical and laboratory characteristics of acute myeloid leukaemia (AML) at relapse and the risk of acute incapacitation.
Q37331218Clinical characteristics and prognosis of acute myeloid leukemia associated with DNA-methylation regulatory gene mutations
Q35900361Clinical evaluation of panel testing by next-generation sequencing (NGS) for gene mutations in myeloid neoplasms
Q48121119Clinical features and prognostic impact of PRDM16 expression in adult acute myeloid leukemia
Q34340438Clinical features of de novo acute myeloid leukemia with concurrent DNMT3A, FLT3 and NPM1 mutations
Q36557537Clinical impact of CD200 expression in patients with acute myeloid leukemia and correlation with other molecular prognostic factors.
Q47936319Clinical impact of KMT2C and SPRY4 expression levels in intensively treated younger adult acute myeloid leukemia patients
Q50631404Clinical impact of SNP of P53 genes pathway on the adult AML patients.
Q41993143Clinical impact of colonization with multidrug-resistant organisms on outcome after allogeneic stem cell transplantation in patients with acute myeloid leukemia.
Q33572303Clinical impact of gene mutations and lesions detected by SNP-array karyotyping in acute myeloid leukemia patients in the context of gemtuzumab ozogamicin treatment: results of the ALFA-0701 trial
Q39653218Clinical impact of leukemic blast heterogeneity at diagnosis in cytogenetic intermediate-risk acute myeloid leukemia
Q37622957Clinical implications of genome-wide DNA methylation studies in acute myeloid leukemia
Q53397583Clinical implications of non-A-type NPM1 and FLT3 mutations in patients with normal karyotype acute myeloid leukemia.
Q57898941Clinical manifestations and diagnosis
Q35265946Clinical outcome and gene- and microRNA-expression profiling according to the Wilms tumor 1 (WT1) single nucleotide polymorphism rs16754 in adult de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study
Q34226754Clinical relevance of mutant NPM1 and CEBPA in patients with acute myeloid leukaemia - preliminary report
Q37065843Clinical role of microRNAs in cytogenetically normal acute myeloid leukemia: miR-155 upregulation independently identifies high-risk patients
Q41693113Clinical significance of newly emerged isolated del(20q) in patients following cytotoxic therapies
Q38031146Clinical studies of acute myeloid leukemia in the Japan Adult Leukemia Study Group
Q33746130Clinical study on prospective efficacy of all-trans Acid, realgar-indigo naturalis formula combined with chemotherapy as maintenance treatment of acute promyelocytic leukemia
Q33968321Clofarabine does not negatively impact the outcomes of patients with acute myeloid leukemia undergoing allogeneic stem cell transplantation
Q41474323Clofarabine salvage therapy before allogeneic hematopoietic stem cell transplantation in patients with relapsed or refractory AML: results of the BRIDGE trial.
Q37429911Clofarabine versus fludarabine-based reduced-intensity conditioning regimen prior to allogeneic transplantation in adults with AML/MDS.
Q60050027Clofarabine/busulfan-based reduced intensity conditioning regimens provides very good survivals in acute myeloid leukemia patients in complete remission at transplant: a retrospective study on behalf of the SFGM-TC
Q96683590Clonal dominance is an adverse prognostic factor in acute myeloid leukemia treated with intensive chemotherapy
Q93067058Clonal evolution of acute myeloid leukemia from diagnosis to relapse
Q64071463Clonal evolution patterns in acute myeloid leukemia with NPM1 mutation
Q56968572Clonal heterogeneity of -ITD detected by high-throughput amplicon sequencing correlates with adverse prognosis in acute myeloid leukemia
Q39888679Close correlation of copy number aberrations detected by next-generation sequencing with results from routine cytogenetics in acute myeloid leukemia
Q57898900Coexpression profile of leukemic stem cell markers for combinatorial targeted therapy in AML
Q61811335Colonization with multidrug resistant organisms determines the clinical course of patients with acute myeloid leukemia undergoing intensive induction chemotherapy
Q58779455Combination of ATO with FLT3 TKIs eliminates FLT3/ITD+ leukemia cells through reduced expression of FLT3
Q34348102Combination of fludarabine, amsacrine, and cytarabine followed by reduced-intensity conditioning and allogeneic hematopoietic stem cell transplantation in patients with high-risk acute myeloid leukemia
Q36925156Combined molecular and clinical prognostic index for relapse and survival in cytogenetically normal acute myeloid leukemia
Q83436488Comorbidity as a risk factor for overall survival and decision criteria for intensity of chemotherapy in elderly patients with acute myeloid leukemia
Q34620456Comparable survival after HLA-well-matched unrelated or matched sibling donor transplantation for acute myeloid leukemia in first remission with unfavorable cytogenetics at diagnosis
Q44824037Comparative outcome of reduced intensity and myeloablative conditioning regimen in HLA identical sibling allogeneic hematopoietic stem cell transplantation for acute leukemia patients: a single center experience
Q53001093Comparative therapeutic value of post-remission approaches in patients with acute myeloid leukemia aged 40-60 years.
Q39601810Comparative value of post-remission treatment in cytogenetically normal AML subclassified by NPM1 and FLT3-ITD allelic ratio
Q46888442Comparing leukapheresis protocols for an AML patient with symptomatic leukostasis
Q51704129Comparison of Multiparameter Flow Cytometry Immunophenotypic Analysis and Quantitative RT-PCR for the Detection of Minimal Residual Disease of Core Binding Factor Acute Myeloid Leukemia.
Q33830964Comparison of matched sibling donors versus unrelated donors in allogeneic stem cell transplantation for primary refractory acute myeloid leukemia: a study on behalf of the Acute Leukemia Working Party of the EBMT.
Q34627218Comparison of minimal residual disease as outcome predictor for AML patients in first complete remission undergoing myeloablative or nonmyeloablative allogeneic hematopoietic cell transplantation
Q46788345Comparison of outcomes after single or double cord blood transplantation in adults with acute leukemia using different types of myeloablative conditioning regimen, a retrospective study on behalf of Eurocord and the Acute Leukemia Working Party of E
Q48199548Comparison of outcomes after unrelated cord blood and unmanipulated haploidentical stem cell transplantation in adults with acute leukemia
Q34630588Comparison of reduced-intensity hematopoietic cell transplantation with chemotherapy in patients age 60-70 years with acute myelogenous leukemia in first remission
Q28546572Complementation of the Yeast Model System Reveals that Caenorhabditis elegans OCT-1 Is a Functional Transporter of Anthracyclines
Q45221235Complete remission after a single cycle of azacitidine in a case of relapsed acute myeloid leukemia
Q55404461Complex Karyotype in Hematological Diseases: A 6-Year Single Centre Study from Pakistan.
Q33421005Complex karyotype, older age, and reduced first-line dose intensity determine poor survival in core binding factor acute myeloid leukemia patients with long-term follow-up.
Q41197435Complex molecular genetic abnormalities involving three or more genetic mutations are important prognostic factors for acute myeloid leukemia
Q59330143Compound kushen injection suppresses human acute myeloid leukaemia by regulating the Prdxs/ROS/Trx1 signalling pathway
Q44467514Comprehensive analysis of genetic alterations and their prognostic impacts in adult acute myeloid leukemia patients
Q33758306Comprehensive mutational profiling of core binding factor acute myeloid leukemia
Q37575953Comprehensive study on ERG gene expression in normal karyotype acute myeloid leukemia: ERG expression is of limited prognostic value, whereas the accumulation of adverse prognostic markers stepwise worsens the prognosis
Q40147710Concurrent detection of targeted copy number variants and mutations using a myeloid malignancy next generation sequencing panel allows comprehensive genetic analysis using a single testing strategy
Q40197450Condensed versus standard schedule of high-dose cytarabine consolidation therapy with pegfilgrastim growth factor support in acute myeloid leukemia
Q35647641Conditioning intensity in middle-aged patients with AML in first CR: no advantage for myeloablative regimens irrespective of the risk group-an observational analysis by the Acute Leukemia Working Party of the EBMT.
Q38229633Conditioning regimens in acute myeloid leukemia
Q90253675Conjugation of haematopoietic stem cells and platelets decorated with anti-PD-1 antibodies augments anti-leukaemia efficacy
Q36107268Connect MDS/AML: design of the myelodysplastic syndromes and acute myeloid leukemia disease registry, a prospective observational cohort study
Q35040043Connexin expression in human acute myeloid leukemia cells: identification of patient subsets based on protein and global gene expression profiles
Q36633055Continued improvement in survival of acute myeloid leukemia patients: an application of the loss in expectation of life
Q39337506Copy-number analysis identified new prognostic marker in acute myeloid leukemia
Q92587525Core Data Elements in Acute Myeloid Leukemia: A Unified Medical Language System-Based Semantic Analysis and Experts' Review
Q37084121Correlation of NPM1 Type A Mutation Burden With Clinical Status and Outcomes in Acute Myeloid Leukemia Patients With Mutated NPM1 Type A.
Q57483591Cost-effectiveness analysis for midostaurin versus standard of care in acute myeloid leukemia in the United Kingdom
Q64276608Current Outlook on Autophagy in Human Leukemia: Foe in Cancer Stem Cells and Drug Resistance, Friend in New Therapeutic Interventions
Q34604460Current knowledge and future research directions in treatment-related second primary malignancies
Q40256523Cytarabine, aclarubicin and granulocyte colony-stimulating factor regimen represents an effective and safe salvage regimen for patients with acute myeloid leukemia refractory to first course of induction chemotherapy
Q35146284Cytogenetic heterogeneity negatively impacts outcomes in patients with acute myeloid leukemia
Q39732854Cytogenetic profiles of 2806 patients with acute myeloid leukemia-a retrospective multicenter nationwide study
Q39002065Cytogenetic risk determines outcomes after allogeneic transplantation in older patients with acute myeloid leukemia in their second complete remission: A Center for International Blood and Marrow Transplant Research cohort analysis
Q57058970Cytogenetics and gene mutations influence survival in older patients with acute myeloid leukemia treated with azacitidine or conventional care
Q39414681Cytokine Release Patterns in Mixed Lymphocyte Culture (MLC) of T-Cells with Dendritic Cells (DC) Generated from AML Blasts Contribute to Predict anti-Leukaemic T-Cell Reactions and Patients' Response to Immunotherapy
Q33703046Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia
Q45397622Cytological characterization of murine bone marrow and spleen hematopoietic compartments for improved assessment of toxicity in preclinical gene marking models
Q37349113Cytoplasmic proliferating cell nuclear antigen connects glycolysis and cell survival in acute myeloid leukemia
Q90028993Cytotoxic therapy in acute myeloid leukemia: not quite dead yet
Q35640809DECIDER: prospective randomized multicenter phase II trial of low-dose decitabine (DAC) administered alone or in combination with the histone deacetylase inhibitor valproic acid (VPA) and all-trans retinoic acid (ATRA) in patients >60 years with acu
Q47132650DNA damage in acute myeloid leukemia patients of Northern Mexico
Q37797467DNA methylation profiling in acute myeloid leukemia: from recent technological advances to biological and clinical insights
Q34661033DNMT3A and IDH mutations in acute myeloid leukemia and other myeloid malignancies: associations with prognosis and potential treatment strategies
Q27851689DNMT3A mutations and response to the hypomethylating agent decitabine in acute myeloid leukemia
Q38282093DNMT3A: the DioNysian MonsTer of acute myeloid leukaemia.
Q37675217DOCK2 interacts with FLT3 and modulates the survival of FLT3-expressing leukemia cells
Q37166721Daunorubicin, cytarabine, and cladribine regimen plus radiotherapy and donor lymphocyte infusion for extramedullary relapse of acute myeloid leukemia after hematopoietic stem cell transplantation
Q54336601De novo acute myeloid leukemia with 20-29% blasts is less aggressive than acute myeloid leukemia with ≥30% blasts in older adults: a Bone Marrow Pathology Group study.
Q36304111Deacetylase inhibitors modulate proliferation and self-renewal properties of leukemic stem and progenitor cells.
Q41104655Decitabine improves progression-free survival in older high-risk MDS patients with multiple autosomal monosomies: results of a subgroup analysis of the randomized phase III study 06011 of the EORTC Leukemia Cooperative Group and German MDS Study Gro
Q50463311Decitabine reduces transfusion dependence in older patients with acute myeloid leukemia: results from a post hoc analysis of a randomized phase III study.
Q33407030Decitabine: a review of its use in older patients with acute myeloid leukaemia
Q36554393Decreased invasive fungal disease but no impact on overall survival by posaconazole compared to fluconazole prophylaxis: a retrospective cohort study in patients receiving induction therapy for acute myeloid leukaemia/myelodysplastic syndromes
Q41708770Defining a therapeutic window for kinase inhibitors in leukemia to avoid neutropenia
Q26772235Defining and Treating Older Adults with Acute Myeloid Leukemia Who Are Ineligible for Intensive Therapies
Q52896167Definition of GvHD-free, relapse-free survival for registry-based studies: an ALWP-EBMT analysis on patients with AML in remission.
Q34516262Deletion of TAK1 in the myeloid lineage results in the spontaneous development of myelomonocytic leukemia in mice
Q41688469Dendritic cells in bone marrow at diagnosis and after chemotherapy in adult patients with acute myeloid leukaemia
Q28538139Deregulation of mitochondrial ATPsyn-β in acute myeloid leukemia cells and with increased drug resistance
Q39188673Deregulation of protein phosphatase expression in acute myeloid leukemia
Q38918850Design of the randomized, Phase III, QUAZAR AML Maintenance trial of CC-486 (oral azacitidine) maintenance therapy in acute myeloid leukemia
Q33795203Detailed Characterization of Mesenchymal Stem/Stromal Cells from a Large Cohort of AML Patients Demonstrates a Definitive Link to Treatment Outcomes
Q53791265Detection of clonal heterogeneity and targetable mutations in myeloid sarcoma by high-throughput sequencing.
Q37999070Detection of copy number alterations in acute myeloid leukemia and myelodysplastic syndromes
Q47774723Determinants of 1-year survival in critically ill acute leukemia patients: a GRRR-OH study
Q54958123Developing and piloting an instrument to prioritize the worries of patients with acute myeloid leukemia.
Q37493869Developing aptamer probes for acute myelogenous leukemia detection and surface protein biomarker discovery
Q47648441Development and Validation of a Novel Acute Myeloid Leukemia-Composite Model to Estimate Risks of Mortality
Q52673676Development and Validation of a Novel RNA Sequencing-Based Prognostic Score for Acute Myeloid Leukemia.
Q90160549Development and validation of a 10-gene prognostic signature for acute myeloid leukaemia
Q37076434Development and validation of a comprehensive genomic diagnostic tool for myeloid malignancies
Q48142237Development of a NanoString assay to detect leukemogenic fusion transcripts in acute myeloid leukemia
Q38103753Developmental therapeutics in acute myelogenous leukemia: are there any new effective cytotoxic chemotherapeutic agents out there?
Q88007476Dexamethasone in hyperleukocytic acute myeloid leukemia
Q64119614Di--lauroyl-decitabine-lipid nanocapsules: toward extending decitabine activity
Q38240563Diagnosing and following adult patients with acute myeloid leukaemia in the genomic age.
Q38608903Diagnosis and Therapy of Acute Myeloid Leukemia in the Era of Molecular Risk Stratification
Q37624593Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel
Q39285462Diagnostic & prognostic role of microRNAs in paediatric acute myeloid leukaemia.
Q57898947Diagnostic criteria, classification, and prognosis of acute leukemias
Q46516275Differences in proliferative capacity of primary human acute myelogenous leukaemia cells are associated with altered gene expression profiles and can be used for subclassification of patients
Q92242805Differential Interaction of Peripheral Blood Lymphocyte Counts (ALC) With Different in vivo Depletion Strategies in Predicting Outcomes of Allogeneic Transplant: An International 2 Center Experience
Q26991736Discovery and development of the Polo-like kinase inhibitor volasertib in cancer therapy
Q37699220Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation
Q52608845Distinct Metabolic features differentiating FLT3-ITD AML from FLT3-WT childhood Acute Myeloid Leukemia.
Q37079676Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia.
Q47353129Distinct factors determine the kinetics of disease relapse in adults transplanted for acute myeloid leukaemia.
Q28749564Distinct patterns of DNA damage response and apoptosis correlate with Jak/Stat and PI3kinase response profiles in human acute myelogenous leukemia
Q37188719Distress in patients with acute leukemia: a concept analysis
Q27853019Distribution and levels of cell surface expression of CD33 and CD123 in acute myeloid leukemia
Q85934289Distribution of mutations in DNMT3A gene and the suitability of mutations in R882 codon for MRD monitoring in patients with AML
Q27851686Do AML patients with DNMT3A exon 23 mutations benefit from idarubicin as compared to daunorubicin? A single center experience.
Q53804314Does outcome of second salvage therapy in relapsed or refractory acute myeloid leukemia depend on intensity of either first or second salvage therapy?
Q34380060Donor compatibility and performance status affect outcome of allogeneic haematopoietic stem cell transplant in patients with relapsed or refractory acute myeloid leukaemia
Q34502042Double CEBPA mutations are prognostically favorable in non-M3 acute myeloid leukemia patients with wild-type NPM1 and FLT3-ITD.
Q38666159Driving Toward Precision Medicine for Acute Leukemias: Are We There Yet?
Q37888956Drosophila: a model for studying genetic and molecular aspects of haematopoiesis and associated leukaemias
Q47284112Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms.
Q38893052Dual targeting of acute myeloid leukemia progenitors by catalytic mTOR inhibition and blockade of the p110α subunit of PI3 kinase
Q36946572Dynamics of cytotoxic T cell subsets during immunotherapy predicts outcome in acute myeloid leukemia
Q36734783EM23, A Natural Sesquiterpene Lactone from Elephantopus mollis, Induces Apoptosis in Human Myeloid Leukemia Cells through Thioredoxin- and Reactive Oxygen Species-Mediated Signaling Pathways
Q87851748EQUATOR-Oncology: reducing the latitude of cancer trial design and reporting
Q33772607Early aberrant DNA methylation events in a mouse model of acute myeloid leukemia
Q34167404Early allo-SCT for AML with a complex aberrant karyotype--results from a prospective pilot study
Q43555651Early assessment of minimal residual disease in AML by flow cytometry during aplasia identifies patients at increased risk of relapse.
Q90497302Early hospital discharge after intensive induction chemotherapy for adults with acute myeloid leukemia or other high-grade myeloid neoplasm
Q92915912Early peripheral clearance of leukemia-associated immunophenotypes in AML: centralized analysis of a randomized trial
Q60043878Early recovery of the platelet count after decitabine-based induction chemotherapy is a prognostic marker of superior response in elderly patients with newly diagnosed acute myeloid leukaemia
Q34047867Echinomycin protects mice against relapsed acute myeloid leukemia without adverse effect on hematopoietic stem cells
Q37252482Economic impact of genomic diagnostics for intermediate-risk acute myeloid leukaemia
Q52726355Effect of High VEGF-C mRNA Expression on Achievement of Complete Remission in Adult Acute Myeloid Leukemia.
Q33968372Effect of NPM1 and FLT3 mutations on the outcomes of elderly patients with acute myeloid leukemia receiving standard chemotherapy
Q42384543Effect of allogeneic hematopoietic cell transplantation in first complete remission on post-relapse complete remission rate and survival in acute myeloid leukemia
Q38657161Effect of cytogenetic risk status on outcomes for patients with acute myeloid leukemia undergoing various types of allogeneic hematopoietic cell transplantation: an analysis of 7812 patients.
Q33400617Effect of gemtuzumab ozogamicin on survival of adult patients with de-novo acute myeloid leukaemia (ALFA-0701): a randomised, open-label, phase 3 study
Q91699013Effect of postremission high dose cytarabine-based consolidation chemotherapy before allogenic stem cell transplantation in outcomes of acute myeloid leukemia patients
Q51146764Efficacy and feasibility of cyclophosphamide combined with intermediate- dose or high-dose cytarabine for relapsed and refractory acute myeloid leukemia (AML).
Q33434711Efficacy and safety analysis of the combination of cladribine, cytarabine, granulocyte colonystimulating factor (CLAG) regime in patients with refractory or relapsed acute myeloid leukemia
Q41530049Efficacy and safety of different doses of cytarabine in consolidation therapy for adult acute myeloid leukemia patients: a network meta-analysis
Q57073560Efficacy and safety of lenalidomide for the treatment of acute myeloid leukemia: a systematic review and meta-analysis
Q34543909Efficacy of CPX-351, (cytarabine:daunorubicin) liposome injection, against acute lymphoblastic leukemia (ALL) xenograft models of the Pediatric Preclinical Testing Program
Q41175826Efficacy of antifungal prophylaxis with oral suspension posaconazole during induction chemotherapy of acute myeloid leukemia
Q38917137Efficacy of single-agent decitabine in relapsed and refractory acute myeloid leukemia.
Q37429089Efficacy of the hypomethylating agents as frontline, salvage, or consolidation therapy in adults with acute myeloid leukemia (AML).
Q38003665Efficacy of tosedostat, a novel, oral agent for elderly patients with relapsed or refractory acute myeloid leukemia: a review of the Phase II OPAL trial
Q38078423Elacytarabine: lipid vector technology under investigation in acute myeloid leukemia
Q38803880Elevated PIM2 gene expression is associated with poor survival of patients with acute myeloid leukemia.
Q38785380Emerging cell cycle inhibitors for acute myeloid leukemia
Q47670541Emerging molecular predictive and prognostic factors in acute myeloid leukemia
Q38818726Emerging strategies for the treatment of older patients with acute myeloid leukemia.
Q38401664Emerging therapeutic targets for the treatment of human acute myeloid leukemia (part 1) - gene transcription, cell cycle regulation, metabolism and intercellular communication
Q38435352Emerging therapeutic targets in human acute myeloid leukemia (part 2) - bromodomain inhibition should be considered as a possible strategy for various patient subsets
Q41133468Emetine induces chemosensitivity and reduces clonogenicity of acute myeloid leukemia cells
Q43234215Empiric definition of eligibility criteria for clinical trials in relapsed/refractory acute myeloid leukemia: analysis of 1,892 patients from HOVON/SAKK and SWOG.
Q38674045Enasidenib induces acute myeloid leukemia cell differentiation to promote clinical response
Q47120346Enforced GFI1 expression impedes human and murine leukemic cell growth
Q39285841Enhancing acute myeloid leukemia therapy - monitoring response using residual disease testing as a guide to therapeutic decision-making
Q47138685Epidemiological, genetic, and clinical characterization by age of newly diagnosed acute myeloid leukemia based on an academic population-based registry study (AMLSG BiO).
Q38264968Epigenetic alterations in acute myeloid leukemias
Q37635209Epigenetic therapy is associated with similar survival compared with intensive chemotherapy in older patients with newly diagnosed acute myeloid leukemia
Q34350209Epigenetics in clinical practice: the examples of azacitidine and decitabine in myelodysplasia and acute myeloid leukemia
Q58814184Equivalent outcomes using reduced intensity or conventional myeloablative conditioning transplantation for patients aged 35 years and over with AML
Q50226456Establishment and Characterization of Long-Term Cultures Derived from Primary Acute Myeloid Leukemia Cells for HDAC Inhibitor Research.
Q37342223Esterase D and gamma 1 actin level might predict results of induction therapy in patients with acute myeloid leukemia without and with maturation
Q39200282Euphorbia formosana root extract induces apoptosis by caspase-dependent cell death via Fas and mitochondrial pathway in THP-1 human leukemic cells.
Q42616605European LeukemiaNet classification intermediate risk-1 cohort is associated with poor outcomes in adults with acute myeloid leukemia undergoing allogeneic hematopoietic cell transplantation
Q40393514Evaluating the impact of genetic and epigenetic aberrations on survival and response in acute myeloid leukemia patients receiving epigenetic therapy
Q83682066Evaluation of allogeneic hematopoietic SCT in younger adults with adverse karyotype AML
Q35886215Evaluation of bone marrow aspirates in patients with acute myeloid leukemia at day 14 of induction therapy
Q92570562Evaluation of event-free survival as a robust end point in untreated acute myeloid leukemia (Alliance A151614)
Q37318667Evaluation of prognostic factors in patients with relapsed AML: Clonal evolution versus residual disease
Q38179026Evolving treatment strategies in patients with high-risk acute myeloid leukemia
Q57808500Ex vivo and in vivo T cell-depleted allogeneic stem cell transplantation in patients with acute myeloid leukemia in first complete remission resulted in similar overall survival: on behalf of the ALWP of the EBMT and the MSKCC
Q36582324Examination of the FLT3 and NPM1 mutational status in patients with acute myeloid leukemia from southeastern Poland.
Q51089294Exploring the Antitumor Mechanism of High-Dose Cytarabine through the Metabolic Perturbations of Ribonucleotide and Deoxyribonucleotide in Human Promyelocytic Leukemia HL-60 Cells.
Q38973410Exposure-Response Analysis of Alvocidib (Flavopiridol) Treatment by Bolus or Hybrid Administration in Newly Diagnosed or Relapsed/Refractory Acute Leukemia Patients.
Q36254052Expression Profiling of Ribosome Biogenesis Factors Reveals Nucleolin as a Novel Potential Marker to Predict Outcome in AML Patients
Q92284294Expression and functional relevance of long non-coding RNAs in acute myeloid leukemia stem cells
Q34831106Expression and prognostic impact of lncRNAs in acute myeloid leukemia
Q55365672Expression levels of long non-coding RNAs are prognostic for AML outcome.
Q51656832Expression of 4-1BB and its ligand on blasts correlates with prognosis of patients with AML.
Q54211664Expression of Eph A4, Eph B2 and Eph B4 receptors in AML.
Q40790764Expression of RANK-L and in part of PD-1 on blasts in patients with acute myeloid leukemia correlates with prognosis
Q41225296Expression of a passenger miR-9* predicts favorable outcome in adults with acute myeloid leukemia less than 60 years of age.
Q87399852Expression of immune inhibitory receptor ILT3 in acute myeloid leukemia with monocytic differentiation
Q42515217Expression of protein-tyrosine phosphatases in Acute Myeloid Leukemia cells: FLT3 ITD sustains high levels of DUSP6 expression
Q49499257Expression of some ATP-binding cassette transporters in acute myeloid leukemia.
Q53769196Expression profile of heat shock proteins in acute myeloid leukaemia patients reveals a distinct signature strongly associated with FLT3 mutation status--consequences and potentials for pharmacological intervention.
Q64092324Extramedullary acute myeloid leukemia presenting in young adults demonstrates sensitivity to high-dose anthracycline: a subset analysis from ECOG-ACRIN 1900
Q90989428Extramedullary relapses of acute leukemias after allogeneic hematopoietic stem cell transplantation: clinical features, cumulative incidence, and risk factors
Q43188286FLT3 INHIBITORS: RECENT ADVANCES AND PROBLEMS FOR CLINICAL APPLICATION.
Q35048217FLT3 inhibitors in the treatment of acute myeloid leukemia: the start of an era?
Q91845843FLT3 mutations in acute myeloid leukemia: Therapeutic paradigm beyond inhibitor development
Q27028163FLT3 mutations in acute myeloid leukemia: what is the best approach in 2013?
Q33856839FLT3 mutations in myelodysplastic syndrome and chronic myelomonocytic leukemia
Q28289859FLT3 tyrosine kinase inhibitors in acute myeloid leukemia: clinical implications and limitations
Q54243631FLT3-ITD and MLL-PTD influence the expression of MDR-1, MRP-1, and BCRP mRNA but not LRP mRNA assessed with RQ-PCR method in adult acute myeloid leukemia.
Q52902952FLT3-ITD mutations do not impact the outcome of patients allografted with partial T-cell depleted grafts for AML with normal cytogenetics in first complete remission.
Q34890418FLT3-internal tandem duplication and age are the major prognostic factors in patients with relapsed acute myeloid leukemia with normal karyotype
Q89747558FOXM1 regulates leukemia stem cell quiescence and survival in MLL-rearranged AML
Q39031946Factors predicting outcome after allogeneic transplant in refractory acute myeloid leukemia: a retrospective analysis of Gruppo Italiano Trapianto di Midollo Osseo (GITMO).
Q35285004Fate of patients with newly diagnosed acute myeloid leukemia who fail primary induction therapy
Q36022536Favorable clinical outcome and unique characteristics in association with Twist1 overexpression in de novo acute myeloid leukemia
Q34541052Feasibility of azacitidine added to standard chemotherapy in older patients with acute myeloid leukemia--a randomised SAL pilot study
Q94299741Feasibility of minimal residual disease studies by multiparametric flow cytometry for acute myeloid leukemia in a developing country
Q53109363Feasibility of the AML profiler (Skyline™ Array) for patient risk stratification in a multicentre trial: a preliminary comparison with the conventional approach.
Q92887026Fertility preservation from the point of view of hematopoietic cell transplant specialists-a worldwide-web-based survey analysis
Q26825765Finding the optimal combination therapy for the treatment of newly diagnosed AML in older patients unfit for intensive therapy
Q47829263Flow cytometric maturity score as a novel prognostic parameter in patients with acute myeloid leukemia.
Q85377254Fludarabine and cytarabine in patients with relapsed acute myeloid leukemia refractory to initial salvage therapy
Q40528087Fludarabine and cytarabine versus high-dose cytarabine in consolidation treatment of t(8; 21) acute myeloid leukemia: A prospective, randomized study
Q50257254Fluorescent In Situ Hybridization in Suspension by Imaging Flow Cytometry.
Q42750992Four cases of chronic myelogenous leukemia in mixed phenotype blast phase at initial presentation mimicking mixed phenotype acute leukemia with t(9;22).
Q58415977Fractionated doses of gemtuzumab ozogamicin with escalated doses of daunorubicin and cytarabine as first acute myeloid leukemia salvage in patients aged 50-70-year old: A phase 1/2 study of the acute leukemia French association
Q33412354Fractionated gemtuzumab ozogamicin and standard dose cytarabine produced prolonged second remissions in patients over the age of 55 years with acute myeloid leukemia in late first relapse
Q39067366Fractionated gemtuzumab ozogamicin combined with intermediate-dose cytarabine and daunorubicin as salvage therapy in very high-risk AML patients: a bridge to reduced intensity conditioning transplant?
Q37249351Frequency of allogeneic hematopoietic cell transplantation among patients with high- or intermediate-risk acute myeloid leukemia in first complete remission
Q35717852Frequency, onset and clinical impact of somatic DNMT3A mutations in therapy-related and secondary acute myeloid leukemia
Q39386021Frequent loss of RAF kinase inhibitor protein expression in acute myeloid leukemia
Q52560331From genomics to targeted treatment in haematological malignancies: a focus on acute myeloid leukaemia.
Q38767583Frontline treatment of acute myeloid leukemia in adults
Q38917587Fruit extract from a Sechium edule hybrid induce apoptosis in leukaemic cell lines but not in normal cells
Q90269165Functional Classification of TP53 Mutations in Acute Myeloid Leukemia
Q33737486Functional characterization of FLT3 receptor signaling deregulation in acute myeloid leukemia by single cell network profiling (SCNP).
Q39332914Functional characterization of the promoter region of the human EVI1 gene in acute myeloid leukemia: RUNX1 and ELK1 directly regulate its transcription.
Q28547905G2/M Cell Cycle Arrest and Tumor Selective Apoptosis of Acute Leukemia Cells by a Promising Benzophenone Thiosemicarbazone Compound
Q33717707GAS6 expression identifies high-risk adult AML patients: potential implications for therapy
Q40086982GATA3 rs3824662 gene polymorphism as possible risk factor in a cohort of Egyptian patients with pediatric acute lymphoblastic leukemia and its prognostic impact.
Q40022463GFI1 as a novel prognostic and therapeutic factor for AML/MDS.
Q91774040Gal9/Tim-3 expression level is higher in AML patients who fail chemotherapy
Q44462005Gemtuzumab ozogamicin in combination with intensive chemotherapy in relapsed or refractory acute myeloid leukemia
Q33558088Gemtuzumab ozogamicin in combination with vorinostat and azacitidine in older patients with relapsed or refractory acute myeloid leukemia: a phase I/II study
Q37910260Gemtuzumab ozogamicin in non-acute promyelocytic acute myeloid leukemia
Q47136441Gene Mutations as Emerging Biomarkers and Therapeutic Targets for Relapsed Acute Myeloid Leukemia
Q91643172Gene coexpression network analysis revealed biomarkers correlated with blast cells and survival in acute myeloid leukemia
Q59793120Gene expression of , , , and topoisomerase IIα as an indicator of chemotherapy response in AML treated with cytarabine and daunorubicin
Q35302035Gene expression profiles associated with pediatric relapsed AML.
Q37858877Gene expression profiling in MDS and AML: potential and future avenues.
Q47235517Gene expression profiling of acute myeloid leukemia samples from adult patients with AML-M1 and -M2 through boutique microarrays, real-time PCR and droplet digital PCR.
Q34347096Gene mutation patterns in patients with minimally differentiated acute myeloid leukemia
Q34647741Gene mutations and molecularly targeted therapies in acute myeloid leukemia.
Q38077505Gene mutations of acute myeloid leukemia in the genome era.
Q55025720Genetic alterations and their clinical implications in older patients with acute myeloid leukemia.
Q38044773Genetic biomarkers in acute myeloid leukemia: will the promise of improving treatment outcomes be realized?
Q38509706Genetic mutations in epigenetic modifiers as therapeutic targets in acute myeloid leukemia
Q39942266Genetic variants involved in oxidative stress, base excision repair, DNA methylation, and folate metabolism pathways influence myeloid neoplasias susceptibility and prognosis
Q34221312Genome wide analysis of acute myeloid leukemia reveal leukemia specific methylome and subtype specific hypomethylation of repeats.
Q27853389Genomic Classification and Prognosis in Acute Myeloid Leukemia
Q29615735Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia
Q38223490Genomic characterization of acute leukemias
Q33939071Genomic imbalances are confined to non-proliferating cells in paediatric patients with acute myeloid leukaemia and a normal or incomplete karyotype
Q37075666Geriatric assessment in older patients with acute myeloid leukemia: a retrospective study of associated treatment and outcomes
Q47903598Gingival enlargement in a pregnant woman with acute monocytic leukaemia: a case report
Q40254512Glucose-6-phosphate dehydrogenase deficiency and risk of invasive fungal disease in patients with acute myeloid leukemia
Q35940547Gold nanoparticles enhance the effect of tyrosine kinase inhibitors in acute myeloid leukemia therapy.
Q27027798Granulocytic sarcoma: a systematic review
Q38920692Great expectations in acute myeloid leukemia
Q92581870HMGA2 regulates acute myeloid leukemia progression and sensitivity to daunorubicin via Wnt/β-catenin signaling
Q36336147HO-1, RET and PML as possible markers for risk stratification of acute myelocytic leukemia and prognostic evaluation
Q38753227HOX gene expression predicts response to BCL-2 inhibition in acute myeloid leukemia.
Q43065853HOXA/PBX3 knockdown impairs growth and sensitizes cytogenetically normal acute myeloid leukemia cells to chemotherapy
Q92918139Haploidentical, Unmanipulated Granulocyte Colony-Stimulating Factor (G-CSF)-Primed Peripheral Blood Stem Cell Transplants for Acute Myeloid Leukemia (AML) in Remission: A Single Center Experience
Q35564902Health care utilization and end-of-life care for older patients with acute myeloid leukemia
Q48467983Health related quality of life and impact of infectious comorbidity in outpatient management of patients with acute leukemia.
Q53543462Health-Related Quality of Life of Patients with Acute Myeloid Leukemia: A Systematic Literature Review.
Q38222563Heat shock protein 70 - the next chaperone to target in the treatment of human acute myelogenous leukemia?
Q37216297Helicase-like transcription factor is a RUNX1 target whose downregulation promotes genomic instability and correlates with complex cytogenetic features in acute myeloid leukemia
Q36961604Hematologic Recovery after Pretransplant Chemotherapy Does Not Influence Survival after Allogeneic Hematopoietic Cell Transplantation in Acute Myeloid Leukemia Patients
Q58719438Hematopoietic cell transplant for acute myeloid leukemia and myelodysplastic syndrome: conditioning regimen intensity
Q90441706Hematopoietic stem cell transplantation for children with acute myeloid leukemia-results of the AML SCT-BFM 2007 trial
Q33841129Hematopoietic stem cell transplantation rates and long-term survival in acute myeloid and lymphoblastic leukemia: real-world population-based data from the Swedish Acute Leukemia Registry 1997-2006.
Q57143658Hexosamine Biosynthetic Pathway Inhibition Leads to AML Cell Differentiation and Cell Death
Q60932672Hif-1α Deletion May Lead to Adverse Treatment Effect in a Mouse Model of MLL-AF9-Driven AML
Q47156797High BAALC copy numbers in peripheral blood prior to allogeneic transplantation predict early relapse in acute myeloid leukemia patients
Q35629275High Doses of Daunorubicin during Induction Therapy of Newly Diagnosed Acute Myeloid Leukemia: A Systematic Review and Meta-Analysis of Prospective Clinical Trials
Q49615274High EVI1 Expression Predicts Poor Outcomes in Adult Acute Myeloid Leukemia Patients with Intermediate Cytogenetic Risk Receiving Chemotherapy.
Q37510247High Expression of CPT1A Predicts Adverse Outcomes: A Potential Therapeutic Target for Acute Myeloid Leukemia.
Q41670609High IDH1 expression is associated with a poor prognosis in cytogenetically normal acute myeloid leukemia
Q92567745High IL2RA mRNA expression is an independent adverse prognostic biomarker in core binding factor and intermediate-risk acute myeloid leukemia
Q35659664High Incidences of Invasive Fungal Infections in Acute Myeloid Leukemia Patients Receiving Induction Chemotherapy without Systemic Antifungal Prophylaxis: A Prospective Observational Study in Taiwan
Q42285092High Prevalence of Vitamin D Deficiency in Newly Diagnosed Acute Myeloid Leukemia Patients and Its Adverse Outcome
Q54517330High activity of sorafenib in FLT3-ITD-positive acute myeloid leukemia synergizes with allo-immune effects to induce sustained responses.
Q35988637High dose cytarabine, mitoxantrone and l-asparaginase (HAMA) salvage for relapsed or refractory acute myeloid leukemia (AML) in the elderly
Q91276827High expression levels of SMAD3 and SMAD7 at diagnosis predict poor prognosis in acute myeloid leukemia patients undergoing chemotherapy
Q47283332High expression of FLT3 is a risk factor in leukemia
Q33623126High expression of IGFBP2 is associated with chemoresistance in adult acute myeloid leukemia
Q53436427High expression of OCT4 is frequent and may cause undesirable treatment outcomes in patients with acute myeloid leukemia.
Q35741669High expression of inositol 1,4,5-trisphosphate receptor, type 2 (ITPR2) as a novel biomarker for worse prognosis in cytogenetically normal acute myeloid leukemia
Q43057948High expression of transcription factor 4 (TCF4) is an independent adverse prognostic factor in acute myeloid leukemia that could guide treatment decisions
Q38809840High feasibility and antileukemic efficacy of fludarabine, cytarabine, and idarubicin (FLAI) induction followed by risk-oriented consolidation: A critical review of a 10-year, single-center experience in younger, non M3 AML patients
Q39283692High fms-like tyrosine kinase-3 (FLT3) receptor surface expression predicts poor outcome in FLT3 internal tandem duplication (ITD) negative patients in adult acute myeloid leukaemia: A prospective pilot study from India
Q36545112High frequency of additional gene mutations in acute myeloid leukemia with MLL partial tandem duplication: DNMT3A mutation is associated with poor prognosis
Q44662780High numbers of mobilized CD34+ cells collected in AML in first remission are associated with high relapse risk irrespective of treatment with autologous peripheral blood SCT or autologous BMT.
Q41478883High-dose cytarabine as salvage therapy for relapsed or refractory acute myeloid leukemia--is more better or more of the same?
Q87823188High-dose idarubicin plus busulfan as conditioning regimen to autologous stem cell transplantation: promising post-remission therapy for acute myeloid leukemia in first complete remission?
Q35849281High-resolution genomic profiling of adult and pediatric core-binding factor acute myeloid leukemia reveals new recurrent genomic alterations
Q42847819High-throughput mutational screening adds clinically important information in myelodysplastic syndromes and secondary or therapy-related acute myeloid leukemia
Q33393381Histamine dihydrochloride: in the management of acute myeloid leukaemia
Q48227196History of consolidation is prognostic in acute myeloid leukemia patients undergoing allogeneic hematopoietic cell transplantation in minimal residual disease-negative first complete remission.
Q45111985Homoharringtonine-based induction regimens for patients with de-novo acute myeloid leukaemia: a multicentre, open-label, randomised, controlled phase 3 trial
Q88890106How I treat older patients with acute myeloid leukemia
Q37960820How to manage high-risk acute myeloid leukemia
Q37351908Human BDH2, an anti-apoptosis factor, is a novel poor prognostic factor for de novo cytogenetically normal acute myeloid leukemia
Q39706444Hyper-recovery of platelets after induction therapy is a predictor of relapse-free survival in acute myeloid leukemia
Q58481777Hyperdiploidy with 49–65 chromosomes represents a heterogeneous cytogenetic subgroup of acute myeloid leukemia with differential outcome
Q38126922Hyperleukocytosis and leukocytapheresis in acute leukaemias: experience from a single centre and review of the literature of leukocytapheresis in acute myeloid leukaemia
Q39038221Hyperleukocytosis and leukostasis: management of a medical emergency
Q92091391Hypomethylating agent alters the immune microenvironment in acute myeloid leukaemia (AML) and enhances the immunogenicity of a dendritic cell/AML vaccine
Q24186284Hypomethylating agents for adult patients with acute myeloid leukaemia
Q24234645Hypomethylating agents for adult patients with acute myeloid leukaemia
Q88446399Hypomethylating agents in relapsed and refractory AML: outcomes and their predictors in a large international patient cohort
Q39014493Hypothesis: Tim-3/galectin-9, a new pathway for leukemia stem cells survival by promoting expansion of myeloid-derived suppressor cells and differentiating into tumor-associated macrophages
Q90654871IDH Mutations in AML Patients; A higher Association with Intermediate Risk Cytogenetics
Q33897586IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study
Q28066926IDH1 and IDH2 mutations as novel therapeutic targets: current perspectives
Q44928836IDH1 and IDH2 mutations confer an adverse effect in patients with acute myeloid leukemia lacking the NPM1 mutation
Q42415934IDH1 and IDH2 mutations in myeloid neoplasms--novel paradigms and clinical implications
Q42867437IDH2 mutations in patients with acute myeloid leukemia: missense p.R140 mutations are linked to disease status.
Q36379310IL-8 as mediator in the microenvironment-leukaemia network in acute myeloid leukaemia.
Q57927278IMiDs mobilize acute myeloid leukemia blasts to peripheral blood through downregulation of CXCR4 but fail to potentiate AraC/Idarubicin activity in preclinical models of non del5q/5q- AML
Q24200407Idarubicin compared to other anthracyclines for treatment of newly diagnosed acute myeloid leukaemia
Q36716744Idarubicin, cytarabine, and pravastatin as induction therapy for untreated acute myeloid leukemia and high-risk myelodysplastic syndrome.
Q92828677Identification of CD318 (CDCP1) as novel prognostic marker in AML
Q93059414Identification of FLT3 and NPM1 Mutations in Patients with Acute Myeloid Leukaemia
Q36678141Identification of a 24-gene prognostic signature that improves the European LeukemiaNet risk classification of acute myeloid leukemia: an international collaborative study
Q53289961Identification of a novel fusion TBL1XR1-PDGFRB in a patient with acute myeloid leukemia harboring the DEK-NUP214 fusion and clinical response to dasatinib.
Q54324221Identification of a subset of patients with acute myeloid leukemia characterized by long-term in vitro proliferation and altered cell cycle regulation of the leukemic cells.
Q58699070Identification of long non-coding RNA competing interactions and biological pathways associated with prognosis in pediatric and adolescent cytogenetically normal acute myeloid leukemia
Q21132375Identification of novel molecular markers for prognosis estimation of acute myeloid leukemia: over-expression of PDCD7, FIS1 and Ang2 may indicate poor prognosis in pretreatment patients with acute myeloid leukemia
Q39783129Identifying Prognostic SNPs in Clinical Cohorts: Complementing Univariate Analyses by Resampling and Multivariable Modeling
Q38694866Identifying high-risk adult AML patients: epigenetic and genetic risk factors and their implications for therapy.
Q35054860Identifying the similarities and differences between single nucleotide polymorphism array (SNPa) analysis and karyotyping in acute myeloid leukemia and myelodysplastic syndromes
Q47156715Image-based ex-vivo drug screening for patients with aggressive haematological malignancies: interim results from a single-arm, open-label, pilot study
Q38683676Immune evasion by oncogenic proteins of acute myeloid leukemia
Q90239928ImmunoPET, [64Cu]Cu-DOTA-Anti-CD33 PET-CT, Imaging of an AML Xenograft Model
Q84661264Immunophenotype distinction between acute promyelocytic leukaemia and CD15- CD34- HLA-DR- acute myeloid leukaemia with nucleophosmin mutations
Q36700481Immunovirotherapy with vesicular stomatitis virus and PD-L1 blockade enhances therapeutic outcome in murine acute myeloid leukemia
Q39140034Impact of ABCB1 single nucleotide polymorphisms 1236C>T and 2677G>T on overall survival in FLT3 wild-type de novo AML patients with normal karyotype
Q90702553Impact of Bone Marrow Aspirate Tregs on the Response Rate of Younger Newly Diagnosed Acute Myeloid Leukemia Patients
Q95725155Impact of Day 14 Bone Marrow Biopsy on Re-Induction Decisions and Prediction of a Complete Response in Acute Myeloid Leukemia Cases
Q39040937Impact of FAB classification on predicting outcome in acute myeloid leukemia, not otherwise specified, patients undergoing allogeneic stem cell transplantation in CR1: An analysis of 1690 patients from the acute leukemia working party of EBMT.
Q90911358Impact of FLT3-ITD allele ratio and ITD length on therapeutic outcome in cytogenetically normal AML patients without NPM1 mutation
Q89483800Impact of Wilms' tumor 1 expression on outcome of patients undergoing allogeneic stem cell transplantation for AML
Q42573844Impact of additional genetic alterations on the outcome of patients with NPM1-mutated cytogenetically normal acute myeloid leukemia.
Q40216218Impact of age on outcomes of allogeneic hematopoietic stem cell transplantation with reduced intensity conditioning in elderly patients with acute myeloid leukemia
Q46169540Impact of allogeneic haematopoietic stem cell transplantation in patients with abnl(17p) acute myeloid leukaemia
Q40957638Impact of allogeneic hematopoietic cell transplant in patients with myeloid neoplasms carrying spliceosomal mutations
Q36216242Impact of body-mass index on the outcome of adult patients with acute myeloid leukemia
Q48312577Impact of body-surface area on patients' outcome in younger adults with acute myeloid leukemia.
Q50561478Impact of chemotherapy delay on short- and long-term survival in younger and older AML patients: a Danish population-based cohort study.
Q47903276Impact of cytogenetics risk on outcome after reduced intensity conditioning allo-SCT from an HLA-identical sibling for patients with AML in first CR: a report from the acute leukemia working party of EBMT.
Q84379433Impact of graft-versus-host disease after reduced-intensity conditioning allogeneic stem cell transplantation for acute myeloid leukemia: a report from the Acute Leukemia Working Party of the European group for blood and marrow transplantation
Q90316154Impact of induction regimen and allogeneic hematopoietic cell transplantation on outcome in younger adults with acute myeloid leukemia with a monosomal karyotype
Q38772230Impact of killer-immunoglobulin-like receptor and human leukocyte antigen genotypes on the efficacy of immunotherapy in acute myeloid leukemia
Q43616985Impact of low-dose TBI on outcomes of reduced intensity conditioning allogeneic hematopoietic stem cell transplantation for AML.
Q42724137Impact of molecular prognostic factors in cytogenetically normal acute myeloid leukemia at diagnosis and relapse
Q41176272Impact of obesity in favorable-risk AML patients receiving intensive chemotherapy
Q53132420Impact of postremission consolidation chemotherapy on outcome after reduced-intensity conditioning allogeneic stem cell transplantation for patients with acute myeloid leukemia in first complete remission: a report from the Acute Leukemia Working Pa
Q44140205Impact of pre-transplant disease burden on the outcome of allogeneic hematopoietic stem cell transplant in refractory and relapsed acute myeloid leukemia: a single-center study
Q53114550Impact of pre-transplant marrow blasts on survival of allogeneic stem cell transplantation in adult acute myeloid leukemia.
Q92890451Impact of pretransplant measurable residual disease on the outcome of allogeneic hematopoietic cell transplantation in adult monosomal karyotype AML
Q33646183Impact of pretreatment characteristics and salvage strategy on outcome in patients with relapsed acute myeloid leukemia
Q50923400Impact of salvage regimens on response and overall survival in acute myeloid leukemia with induction failure.
Q44242756Impact of the revised International Prognostic Scoring System on the outcome of patients with acute myeloid leukemia with or without antecedent myelodysplastic syndrome
Q49566124Improved outcome for AML patients over the years 2000-2014.
Q85217276Improved outcome of patients with low- and intermediate-risk cytogenetics acute myeloid leukemia (AML) in first relapse with gemtuzumab and cytarabine versus cytarabine: results of a retrospective comparative study
Q27336142Improvements in the early death rate among 9380 patients with acute myeloid leukemia after initial therapy: A SEER database analysis
Q35179674Improving the outcomes of elderly patients with acute myeloid leukemia in a Brazilian University Hospital.
Q39023971In Vitro Characterization of Valproic Acid, ATRA, and Cytarabine Used for Disease-Stabilization in Human Acute Myeloid Leukemia: Antiproliferative Effects of Drugs on Endothelial and Osteoblastic Cells and Altered Release of Angioregulatory Mediator
Q37701604In vitro and in vivo anti-leukemic activity of the peptidase-potentiated alkylator melflufen in acute myeloid leukemia
Q37014257In vivo targeting of leukemia stem cells by directing parthenolide-loaded nanoparticles to the bone marrow niche
Q41051992Incidence and outcomes for adults diagnosed with acute myeloid leukemia in the north of England: a real world study
Q89935888Incidence and prognostic impact of ASXL2 mutations in adult acute myeloid leukemia patients with t(8;21)(q22;q22): a study of the German-Austrian AML Study Group
Q40353774Incidence and prognostic significance of isolated trisomies in adult acute myeloid leukemia: A population-based study from the Swedish AML registry.
Q37621352Incidence and prognostic significance of karyotypic subgroups in older patients with acute myeloid leukemia: the Swedish population-based experience
Q54653299Incidence and significance of FLT3-ITD and NPM1 mutations in patients with normal karyotype acute myeloid leukaemia.
Q51772195Incidence rates of treatment-emergent adverse events and related hospitalization are reduced with azacitidine compared with conventional care regimens in older patients with acute myeloid leukemia.
Q47137669Inclusion and response criteria for clinical trials in relapsed/refractory acute lymphoblastic leukemia and usefulness of historical control trials
Q64261228Incorporation of long non-coding RNA expression profile in the 2017 ELN risk classification can improve prognostic prediction of acute myeloid leukemia patients
Q36022862Increased Expression of miR-23a Mediates a Loss of Expression in the RAF Kinase Inhibitor Protein RKIP.
Q51068076Increased antileukemic effects in human acute myeloid leukemia by combining HSP70 and HSP90 inhibitors.
Q39683672Increased fibrinogen levels at diagnosis are associated with adverse outcome in patients with acute myeloid leukemia
Q40011579Increasing intensity of therapies assigned at diagnosis does not improve survival of adults with acute myeloid leukemia
Q38760193Independent Prognostic Significance of Monosomy 17 and Impact of Karyotype Complexity in Monosomal Karyotype/Complex Karyotype Acute Myeloid Leukemia: Results from Four ECOG-ACRIN Prospective Therapeutic Trials
Q36967098Indications for hematopoietic stem cell transplantation in patients with follicular lymphoma: a consensus project of the EBMT-Lymphoma Working Party
Q90449425Indirect comparison of azacitidine and decitabine for the therapy of elderly patients with acute myeloid leukemia: a systematic review and network meta-analysis
Q33881750Individual patient data meta-analysis of randomized trials evaluating IL-2 monotherapy as remission maintenance therapy in acute myeloid leukemia
Q49972906Individualized vaccination of AML patients in remission is associated with induction of antileukemia immunity and prolonged remissions.
Q37590227Induction mortality, ATRA administration, and resource utilization in a nationally representative cohort of children with acute promyelocytic leukemia in the United States from 1999 to 2009.
Q37226494Induction of Chromosomal Instability via Telomere Dysfunction and Epigenetic Alterations in Myeloid Neoplasia
Q90999919Influence of alternative donor type on early survival after hematopoietic stem cell transplantation for acute myeloid leukemia lacking a sibling donor
Q36862461Influence of molecular subgroups on outcome of acute myeloid leukemia with normal karyotype in 141 patients undergoing salvage allogeneic stem cell transplantation in primary induction failure or beyond first relapse
Q40098547Infusion of a non-HLA-matched ex-vivo expanded cord blood progenitor cell product after intensive acute myeloid leukaemia chemotherapy: a phase 1 trial
Q36450186Inherited mutations in cancer susceptibility genes are common among survivors of breast cancer who develop therapy-related leukemia
Q38989349Inhibition of FLT3 in AML: a focus on sorafenib
Q41965978Inhibition of Mammalian target of rapamycin in human acute myeloid leukemia cells has diverse effects that depend on the environmental in vitro stress
Q33731216Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population
Q41335421Inhibition of autophagy as a treatment strategy for p53 wild-type acute myeloid leukemia
Q39053372Inhibition of protein kinase CK2 with the clinical-grade small ATP-competitive compound CX-4945 or by RNA interference unveils its role in acute myeloid leukemia cell survival, p53-dependent apoptosis and daunorubicin-induced cytotoxicity
Q51139025Inhibition of serotonin receptor type 1 in acute myeloid leukemia impairs leukemia stem cell functionality: a promising novel therapeutic target.
Q41916176Instruction of haematopoietic lineage choices, evolution of transcriptional landscapes and cancer stem cell hierarchies derived from an AML1-ETO mouse model
Q41924355Integrated analysis of the molecular action of Vorinostat identifies epi-sensitised targets for combination therapy.
Q42149280Integrated genomic analyses identify WEE1 as a critical mediator of cell fate and a novel therapeutic target in acute myeloid leukemia.
Q95846594Integrating clinical features with genetic factors enhances survival prediction for adults with acute myeloid leukemia
Q39113916Integrating genomics into prognostic models for AML.
Q46606851Integration of cytogenetic and molecular alterations in risk stratification of 318 patients with de novo non-M3 acute myeloid leukemia.
Q36326271Integration of microarray analysis into the clinical diagnosis of hematological malignancies: How much can we improve cytogenetic testing?
Q35596909Integrative nucleophosmin mutation-associated microRNA and gene expression pattern analysis identifies novel microRNA - target gene interactions in acute myeloid leukemia
Q84948796Intensity of conditioning for allogeneic haemopoetic cell transplantation
Q44507926Intensive care unit management of patients with newly diagnosed acute myeloid leukemia with no organ failure
Q53099469Intensive chemotherapy for elderly patients with acute myelogeneous leukemia: a propensity score analysis by the Japan Hematology and Oncology Clinical Study Group (J-HOCS).
Q37552031Intensive induction is effective in selected octogenarian acute myeloid leukemia patients: prognostic significance of karyotype and selected molecular markers used in the European LeukemiaNet classification
Q33840247Interactions and relevance of blast percentage and treatment strategy among younger and older patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS)
Q37294760Interleukin-15 enhances the proliferation, stimulatory phenotype, and antitumor effector functions of human gamma delta T cells
Q35859212International phase 3 study of azacitidine vs conventional care regimens in older patients with newly diagnosed AML with >30% blasts
Q37437166Intrinsic resistance to PIM kinase inhibition in AML through p38α-mediated feedback activation of mTOR signaling
Q54213024Investigation of a novel biomarker, neuropilin-1, and its application for poor prognosis in acute myeloid leukemia patients.
Q53469467Isolated del(5q) in Patients Following Therapies for Various Malignancies May Not All Be Clinically Significant.
Q33935391Isolated extramedullary breast relapses in inv(16) positive and c-KIT negative acute myeloid leukemia after allogenic hematopoietic stem cell transplantation - description of two cases
Q30433257Isolated gastric myeloid sarcoma: a case report and review of the literature
Q35167878Isolated primary intracranial myeloid sarcoma with neuromeningeal infiltration: A case report
Q39190900JUN is a key transcriptional regulator of the unfolded protein response in acute myeloid leukemia
Q46137752Jagged-1: a new promising factor associated with favorable prognosis in patients with acute myeloid leukemia.
Q42371609KRAS overexpression independent of RAS mutations confers an adverse prognosis in cytogenetically normal acute myeloid leukemia
Q36548075Karyotype complexity and prognosis in acute myeloid leukemia
Q40575708Karyotype plus NPM1 mutation status defines a group of elderly patients with AML (≥60 years) who benefit from intensive post-induction consolidation therapy
Q36761796Karyotypic change between diagnosis and relapse as a predictor of salvage therapy outcome in AML patients
Q41870967Lack of association of IDH1, IDH2 and DNMT3A mutations with outcome in older patients with acute myeloid leukemia treated with hypomethylating agents
Q46523865Lack of objective response of myelodysplastic syndromes and acute myeloid leukemia to decitabine after failure of azacitidine
Q82675574Landscape of TET2 mutations in acute myeloid leukemia
Q38042705Late-phase investigational approaches for the treatment of relapsed/refractory acute myeloid leukemia
Q38060223Leukaemias into the 21st century: part 1: the acute leukaemias
Q40537124Leukapheresis in patients newly diagnosed with acute myeloid leukemia
Q38537725Leukemia diagnosis: today and tomorrow
Q38382105Leukemia research in Germany: the Competence Network Acute and Chronic Leukemias
Q54582393Leukemia-associated antigens are immunogenic and have prognostic value in acute myeloid leukemia.
Q33558780Leukemia-induced phenotypic and functional defects in natural killer cells predict failure to achieve remission in acute myeloid leukemia
Q50447093Leukemic progenitor cells are susceptible to targeting by stimulated cytotoxic T cells against immunogenic leukemia-associated antigens.
Q89158621Leukemic stem cell signatures identify novel therapeutics targeting acute myeloid leukemia
Q91793988Liquid biopsy for minimal residual disease detection in leukemia using a portable blast cell biochip
Q40261211Long term impact of hyperleukocytosis in newly diagnosed acute myeloid leukemia patients undergoing allogeneic stem cell transplantation: An analysis from the acute leukemia working party of the EBMT.
Q50555238Long-Term Outcome of Autologous Hematopoietic Stem Cell Transplantation (AHSCT) for Acute Myeloid Leukemia (AML)- Single Center Retrospective Analysis.
Q34233639Long-term follow-up of cytogenetically normal CEBPA-mutated AML
Q40831363Long-term follow-up of patients with acute myeloid leukemia surviving and free of disease recurrence for at least 2 years after autologous stem cell transplantation: A report from the Acute Leukemia Working Party of the European Society for Blood an
Q45254762Long-term outcomes of patients with intermediate-risk acute myeloid leukemia treated with autologous hematopoietic cell transplant in first complete remission.
Q39361086Long-term results of a prospective randomized trial evaluating G-CSF priming in intensive induction chemotherapy followed by autologous stem cell transplantation in elderly patients with acute myeloid leukemia.
Q37224591Loss of DNAM-1 ligand expression by acute myeloid leukemia cells renders them resistant to NK cell killing.
Q30313615Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia
Q53110546Low CLL-1 Expression Is a Novel Adverse Predictor in 123 Patients with De Novo CD34+ Acute Myeloid Leukemia.
Q24186270Low dose cytarabine monotherapy for acute myeloid leukaemia
Q24234680Low dose cytarabine monotherapy for acute myeloid leukaemia
Q35794120Low expression of MN1 associates with better treatment response in older patients with de novo cytogenetically normal acute myeloid leukemia
Q84365762Low number of invariant NKT cells is associated with poor survival in acute myeloid leukemia
Q56974946Low-dose lenalidomide plus cytarabine induce complete remission that can be predicted by genetic profiling in elderly acute myeloid leukemia patients
Q61445094Lung resistance-related protein (LRP) predicts favorable therapeutic outcome in Acute Myeloid Leukemia
Q94570182Lyon-University Hospital Experience with Gemtuzumab Ozogamicin Therapy in Acute Myeloid Leukemia: a 'Real-Life' Study
Q38862452MK-2206 induces apoptosis of AML cells and enhances the cytotoxicity of cytarabine.
Q34386922MLL3 is a haploinsufficient 7q tumor suppressor in acute myeloid leukemia
Q37688200MLN0128, a novel mTOR kinase inhibitor, disrupts survival signaling and triggers apoptosis in AML and AML stem/ progenitor cells
Q40421685MN1 and PTEN gene expression in acute myeloid leukemia.
Q92512942MRD in AML: The Role of New Techniques
Q37606183MUC1 is a potential target for the treatment of acute myeloid leukemia stem cells
Q88675410MUC1-C drives myeloid leukaemogenesis and resistance to treatment by a survivin-mediated mechanism
Q37457356MUC1-C induces DNA methyltransferase 1 and represses tumor suppressor genes in acute myeloid leukemia
Q41509184Maintenance lenalidomide in combination with 5-azacitidine as post-remission therapy for acute myeloid leukaemia
Q30249246Maintenance therapy in acute myeloid leukemia: an evidence-based review of randomized trials
Q37558778Maintenance therapy with decitabine in younger adults with acute myeloid leukemia in first remission: a phase 2 Cancer and Leukemia Group B Study (CALGB 10503).
Q90053596Management of hyperleukocytosis and impact of leukapheresis among patients with acute myeloid leukemia (AML) on short- and long-term clinical outcomes: a large, retrospective, multicenter, international study
Q36121885Matched and mismatched unrelated donor compared to autologous stem cell transplantation for acute myeloid leukemia in first complete remission: a retrospective, propensity score-weighted analysis from the ALWP of the EBMT
Q33925386Mcl-1 dependence predicts response to vorinostat and gemtuzumab ozogamicin in acute myeloid leukemia.
Q93158360Measurable residual disease-guided treatment with azacitidine to prevent haematological relapse in patients with myelodysplastic syndrome and acute myeloid leukaemia (RELAZA2): an open-label, multicentre, phase 2 trial
Q34618635Mechanisms of cyclic nucleotide phosphodiesterases in modulating T cell responses in murine graft-versus-host disease
Q64108876Mechanisms of drug resistance in acute myeloid leukemia
Q46576832Medium-sized FLT3 internal tandem duplications confer worse prognosis than short and long duplications in a non-elderly acute myeloid leukemia cohort.
Q38628894Mesenchymal stromal cells contribute to quiescence of therapy resistant leukemic cells in acute myeloid leukemia.
Q34673820Meta-analysis of randomised clinical trials comparing idarubicin + cytarabine with daunorubicin + cytarabine as the induction chemotherapy in patients with newly diagnosed acute myeloid leukaemia
Q47862030Methods of Detection of Measurable Residual Disease in AML.
Q52655669MiR-362-5p as a novel prognostic predictor of cytogenetically normal acute myeloid leukemia.
Q41908916MiR-424 and miR-155 deregulated expression in cytogenetically normal acute myeloid leukaemia: correlation with NPM1 and FLT3 mutation status
Q57058463MiR-425 expression profiling in acute myeloid leukemia might guide the treatment choice between allogeneic transplantation and chemotherapy
Q91940133MiR-9 functions as a tumor suppressor in acute myeloid leukemia by targeting CX chemokine receptor 4
Q43850689MicroRNA expression at diagnosis adds relevant prognostic information to molecular categorization in patients with intermediate-risk cytogenetic acute myeloid leukemia.
Q36882358MicroRNA-223 dose levels fine tune proliferation and differentiation in human cord blood progenitors and acute myeloid leukemia.
Q64892224MicroRNA-425 upregulation indicates better prognosis in younger acute myeloid leukemia patients undergoing chemotherapy.
Q33607590MicroRNA-9 plays a role in interleukin-10-mediated expression of E-cadherin in acute myelogenous leukemia cells
Q36511384MicroRNA-mRNA Pairs Associated with Outcome in AML: From In Vitro Cell-Based Studies to AML Patients
Q38712298Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation
Q54275690Mild chronic graft-versus-host disease may alleviate poor prognosis associated with FLT3 internal tandem duplication for adult acute myeloid leukemia following allogeneic stem cell transplantation with myeloablative conditioning in first complete re
Q28073464Minimal Residual Disease in Acute Myeloid Leukemia of Adults: Determination, Prognostic Impact and Clinical Applications
Q37016999Minimal residual disease as a predictive factor for relapse after allogeneic hematopoietic stem cell transplant in adult patients with acute myeloid leukemia in first and second complete remission
Q39505206Minimal residual disease detectable by quantitative assessment of WT1 gene before allogeneic stem cell transplantation in patients in first remission of acute myeloid leukemia has an impact on their future prognosis
Q38494659Minimal residual disease in acute myeloid leukemia--current status and future perspectives
Q33815986Minimal residual disease prior to allogeneic hematopoietic cell transplantation in acute myeloid leukemia: a meta-analysis
Q33422405Mito-FLAG with Ara-C as bolus versus continuous infusion in recurrent or refractory AML--long-term results of a prospective randomized intergroup study of the East German Study Group Hematology/Oncology (OSHO) and the Study Alliance Leukemia (SAL).
Q50858174Mitochondrial cytochrome c oxidase subunit II variations predict adverse prognosis in cytogenetically normal acute myeloid leukaemia.
Q40703300Mitoxantrone and Etoposide for the Treatment of Acute Myeloid Leukemia Patients in First Relapse
Q47164457Mixed phenotype acute leukemia: outcomes with allogeneic stem cell transplantation. A retrospective study from the Acute Leukemia Working Party of the EBMT.
Q37266555Mobilization of CD34(+)CD38(-) hematopoietic stem cells after priming in acute myeloid leukemia
Q47108992Modeling Myeloid Malignancies Using Zebrafish.
Q26799606Molecular Genetic Markers in Acute Myeloid Leukemia
Q38694679Molecular and cytogenetic abnormalities in acute myeloid leukemia: review and case studies
Q37809866Molecular diagnosis of acute myeloid leukemia
Q37082659Molecular dissection of valproic acid effects in acute myeloid leukemia identifies predictive networks
Q38026007Molecular markers in acute myeloid leukaemia
Q38989476Molecular mechanisms of nutlin-3 involve acetylation of p53, histones and heat shock proteins in acute myeloid leukemia
Q26998811Molecular prognostic factors in cytogenetically normal acute myeloid leukemia
Q33978907Molecular response assessment by quantitative real-time polymerase chain reaction after induction therapy in NPM1-mutated patients identifies those at high risk of relapse
Q33925672Molecular therapy for acute myeloid leukaemia
Q38636162Molecularly targeted drug combinations demonstrate selective effectiveness for myeloid- and lymphoid-derived hematologic malignancies.
Q26770394Monitoring minimal residual disease in acute myeloid leukaemia: a review of the current evolving strategies
Q43879358Monitoring of acute myeloid leukemia patients after allogeneic stem cell transplantation employing semi-automated CD34+ donor cell chimerism analysis
Q47745405Monitoring of residual disease by next-generation deep-sequencing of RUNX1 mutations can identify acute myeloid leukemia patients with resistant disease
Q39235100Monitoring therapy responses at the leukemic subclone level by ultra-deep amplicon resequencing in acute myeloid leukemia
Q45176487Monoallelic CEBPA mutations in normal karyotype acute myeloid leukemia: independent favorable prognostic factor within NPM1 mutated patients
Q37079033Monosomal karyotype as an adverse prognostic factor in patients with acute myeloid leukemia treated with allogeneic hematopoietic stem-cell transplantation in first complete remission: a retrospective survey on behalf of the ALWP of the EBMT
Q39276603Monosomal karyotype in myeloid neoplasias: a literature review
Q38212956Multi-color flow cytometric immunophenotyping for detection of minimal residual disease in AML: past, present and future
Q33401766Multicenter, randomized, open-label, phase III trial of decitabine versus patient choice, with physician advice, of either supportive care or low-dose cytarabine for the treatment of older patients with newly diagnosed acute myeloid leukemia
Q40725017Multicentre survey to explore current survival of patients with acute myeloid leukaemia who failed induction chemotherapy.
Q57786919Multilineage dysplasia is associated with a poorer prognosis in patients with de novo acute myeloid leukemia with intermediate-risk cytogenetics and wild-type NPM1
Q35862717Multimerin-1 (MMRN1) as Novel Adverse Marker in Pediatric Acute Myeloid Leukemia: A Report from the Children's Oncology Group
Q90744801Multiomics of azacitidine-treated AML cells reveals variable and convergent targets that remodel the cell-surface proteome
Q85521108Multiplexed targeted sequencing of recurrent fusion genes in acute leukaemia
Q37592204Multivariate and subgroup analyses of a randomized, multinational, phase 3 trial of decitabine vs treatment choice of supportive care or cytarabine in older patients with newly diagnosed acute myeloid leukemia and poor- or intermediate-risk cytogene
Q54185559Mutant Enrichment with 3'-Modified Oligonucleotides (MEMO)-Quantitative PCR for Detection of NPM1 Mutations in Acute Myeloid Leukemia.
Q42143971Mutation Analysis of Isocitrate Dehydrogenase (IDH1/2) and DNA Methyltransferase 3A (DNMT3A) in Thai Patients with Newly Diagnosed Acute Myeloid Leukemia
Q37316165Mutation of NPM1 and FLT3 genes in acute myeloid leukemia and their association with clinical and immunophenotypic features
Q88878953Mutation profiling of 16 candidate genes in de novo acute myeloid leukemia patients
Q37688148Mutation profiling of 19 candidate genes in acute myeloid leukemia suggests significance of DNMT3A mutations
Q64124189Mutational spectrum and prognostic stratification of intermediate-risk acute myeloid leukemia
Q35102301Mutational spectrum of myeloid malignancies with inv(3)/t(3;3) reveals a predominant involvement of RAS/RTK signaling pathways
Q39027793Mutations in AML: prognostic and therapeutic implications
Q37995804Mutations in ASXL1 are associated with poor prognosis across the spectrum of malignant myeloid diseases
Q48267407Mutations in DNMT3A, U2AF1, and EZH2 identify intermediate-risk acute myeloid leukemia patients with poor outcome after CR1.
Q38703904Mutations in epigenetic modifiers in acute myeloid leukemia and their clinical utility.
Q35687895Mutations in the DNMT3A exon 23 independently predict poor outcome in older patients with acute myeloid leukemia: a SWOG report
Q34347935Mutations in the isocitrate dehydrogenase 2 gene and IDH1 SNP 105C > T have a prognostic value in acute myeloid leukemia
Q41465409Myelodysplastic syndromes following therapy with hypomethylating agents (HMAs): development of acute erythroleukemia may not influence assessment of treatment response
Q64265730Myeloid cell leukemia-1 dependence in acute myeloid leukemia: a novel approach to patient therapy
Q39443070Myeloid leukemia with transdifferentiation plasticity developing from T-cell progenitors
Q50976585Myeloid malignancies in the real-world: Occurrence, progression and survival in the UK's population-based Haematological Malignancy Research Network 2004-15.
Q33354547Myeloid neoplasias: what molecular analyses are telling us
Q35079660Myeloid neoplasms after breast cancer: "therapy-related" not an independent poor prognostic factor
Q36618933NK cell expression of natural cytotoxicity receptors may determine relapse risk in older AML patients undergoing immunotherapy for remission maintenance.
Q41472587NKp30 expression is a prognostic immune biomarker for stratification of patients with intermediate-risk acute myeloid leukemia
Q47112939NKp46 expression on NK cells as a prognostic and predictive biomarker for response to allo-SCT in patients with AML.
Q46679237NOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells
Q57387681NPM1 alternative transcripts are upregulated in acute myeloid and lymphoblastic leukemia and their expression level affects patient outcome
Q91963132Nanopore Targeted Sequencing for Rapid Gene Mutations Detection in Acute Myeloid Leukemia
Q33734571Natural Killer Defective Maturation Is Associated with Adverse Clinical Outcome in Patients with Acute Myeloid Leukemia
Q64937338Natural Products and Acute Myeloid Leukemia: A Review Highlighting Mechanisms of Action.
Q51600879Natural killer cells in acute myeloid leukemia patients: from phenotype to transcriptomic analysis.
Q34255206Neoplastic meningitis in patients with acute myeloid leukemia scheduled for allogeneic hematopoietic stem cell transplantation
Q51025557Network-based sub-network signatures unveil the potential for acute myeloid leukemia therapy.
Q38064808Neutropenia-associated outcomes in adults with acute myeloid leukemia receiving cytarabine consolidation chemotherapy with or without granulocyte colony-stimulating factor
Q60357919New drugs in acute myeloid leukemia
Q37418318New recurrent balanced translocations in acute myeloid leukemia and myelodysplastic syndromes: cancer and leukemia group B 8461.
Q41891342New strategies in acute myeloid leukemia: redefining prognostic markers to guide therapy
Q41881090New treatments and strategies in acute myeloid leukemia
Q58001836Newly emerged isolated Del(7q) in patients with prior cytotoxic therapies may not always be associated with therapy-related myeloid neoplasms
Q64118224Next Generation Sequencing in AML-On the Way to Becoming a New Standard for Treatment Initiation and/or Modulation?
Q27690776Next generation sequencing of acute myeloid leukemia: influencing prognosis
Q27853094Next-generation sequencing of acute myeloid leukemia identifies the significance of TP53, U2AF1, ASXL1, and TET2 mutations
Q64242611Non-acute promyelocytic leukemia variant, acute myeloid leukemia with translocation (11;17)
Q36368289Non-leukemic myeloid sarcoma involving the vulva, vagina, and cervix: a case report and literature review
Q39596000Nonleukemic myeloid dendritic cells obtained from autologous stem cell products elicit antileukemia responses in patients with acute myeloid leukemia
Q38420779Normal karyotype acute myeloid leukemia patients with CEBPA double mutation have a favorable prognosis but no survival benefit from allogeneic stem cell transplant
Q36603527Notch pathway activation targets AML-initiating cell homeostasis and differentiation
Q28075654Novel Prognostic and Therapeutic Mutations in Acute Myeloid Leukemia
Q53633307Novel STAT5B-RARA fusion transcript in acute promyelocytic leukemia: identification and treatment response.
Q38664735Novel Therapies for Acute Myeloid Leukemia: Are We Finally Breaking the Deadlock?
Q28646898Novel ZEB2-BCL11B Fusion Gene Identified by RNA-Sequencing in Acute Myeloid Leukemia with t(2;14)(q22;q32)
Q84831447Novel agents in acute myeloid leukemia
Q37259702Novel mTOR inhibitory activity of ciclopirox enhances parthenolide antileukemia activity.
Q28069889Novel therapeutic options in Acute Myeloid Leukemia
Q96643266Novel treatment paradigms in acute myeloid leukemia
Q89768685Nucleophosmin1 (NPM1) abnormality in hematologic malignancies, and therapeutic targeting of mutant NPM1 in acute myeloid leukemia
Q34979564Number of courses of induction therapy independently predicts outcome after allogeneic transplantation for acute myeloid leukemia in first morphological remission
Q52892987Omacetaxine mepesuccinate for the treatment of leukemia.
Q40314122Optimized depletion of chimeric antigen receptor T cells in murine xenograft models of human acute myeloid leukemia
Q38534501Optimizing mobilization strategies in difficult-to-mobilize patients: The role of plerixafor
Q41336256Optimizing peripheral blood stem cells transplantation outcome through amend relapse and graft failure: a review of current literature.
Q28084813Oral Azacitidine (CC-486) for the Treatment of Myelodysplastic Syndromes and Acute Myeloid Leukemia
Q92593944Oral targeted agent versus chemotherapy in acute myeloid leukaemia
Q92572394Outcome and Prognostic Factors of High-Risk Acute Myeloid Leukemia After Allogeneic Hematopoietic Stem Cell Transplantation
Q39252132Outcome of FLT3-ITD-positive acute myeloid leukemia: impact of allogeneic stem cell transplantation and tyrosine kinase inhibitor treatment.
Q33435191Outcome of Patients With Therapy-Related Acute Myeloid Leukemia With or Without a History of Myelodysplasia
Q52938002Outcome of allogeneic hematopoietic stem cell transplantation for cytogenetically normal AML and identification of high-risk subgroup using WT1 expression in association with NPM1 and FLT3-ITD mutations.
Q39036994Outcome of allogeneic hematopoietic stem cell transplantation in adult patients with acute myeloid leukemia harboring trisomy 8.
Q41663607Outcome of allogeneic hematopoietic stem-cell transplantation for adult patients with AML and 11q23/MLL rearrangement (MLL-r AML).
Q36400942Outcome of older adults with cytogenetically normal AML (CN-AML) and FLT3 mutations
Q45340990Outcome of relapse after allogeneic stem cell transplant in patients with acute myeloid leukemia
Q49733444Outcomes after allogeneic hematopoietic stem cell transplantation in patients with acute myeloid leukemia harboring t(7;11)(p15;p15).
Q47751424Outcomes and changes in code status of patients with acute myeloid leukemia undergoing induction chemotherapy who were transferred to the intensive care unit
Q91829180Outcomes for older adults with acute myeloid leukemia after an intensive care unit admission
Q41983363Outcomes of 1st Remission Induction Chemotherapy in Acute Myeloid Leukemia Cytogenetic Risk Groups
Q93112984Outcomes of Intensive Treatment of Adult Acute Myeloid Leukemia Patients: A Retrospective Study From a Single Centre
Q50137423Outcomes of Patients With Relapsed Core Binding Factor-Positive Acute Myeloid Leukemia.
Q33734101Outcomes of Six-Dose High-Dose Cytarabine as a Salvage Regimen for Patients with Relapsed/Refractory Acute Myeloid Leukemia.
Q89779300Outpatient intensive induction chemotherapy for acute myeloid leukemia and high-risk myelodysplastic syndrome
Q35018552Outpatient management following intensive induction chemotherapy for myelodysplastic syndromes and acute myeloid leukemia: a pilot study
Q34418965Outpatient management following intensive induction or salvage chemotherapy for acute myeloid leukemia
Q36771874Overexpression of ATP1B1 predicts an adverse prognosis in cytogenetically normal acute myeloid leukemia
Q28482247Overexpression of MN1 confers resistance to chemotherapy, accelerates leukemia onset, and suppresses p53 and Bim induction
Q35130976Overexpression of Wilms tumor 1 gene as a negative prognostic indicator in acute myeloid leukemia
Q34877897Overexpression of primary microRNA 221/222 in acute myeloid leukemia
Q34124919P-glycoprotein inhibition using valspodar (PSC-833) does not improve outcomes for patients younger than age 60 years with newly diagnosed acute myeloid leukemia: Cancer and Leukemia Group B study 19808
Q37037268Palbociclib treatment of FLT3-ITD+ AML cells uncovers a kinase-dependent transcriptional regulation of FLT3 and PIM1 by CDK6.
Q38835113Panobinostat for the treatment of acute myelogenous leukemia
Q53133815Partial response after induction chemotherapy has clinical relevance in acute myeloid leukaemia.
Q35836470Pathological glycogenesis through glycogen synthase 1 and suppression of excessive AMP kinase activity in myeloid leukemia cells
Q35003602Patient Activation through Counseling and Exercise--Acute Leukemia (PACE-AL)--a randomized controlled trial.
Q36117062Patients with Acute Myeloid Leukemia Admitted to Intensive Care Units: Outcome Analysis and Risk Prediction
Q48247115PcG methylation of the HIST1 cluster defines an epigenetic marker of acute myeloid leukemia
Q38426552Performance of super-SILAC based quantitative proteomics for comparison of different acute myeloid leukemia (AML) cell lines.
Q41948692Peripheral blood WT1 expression predicts relapse in AML patients undergoing allogeneic stem cell transplantation.
Q42365051Peripheral blood blast clearance is an independent prognostic factor for survival and response to acute myeloid leukemia induction chemotherapy
Q37338371Persistence of DNMT3A R882 mutations during remission does not adversely affect outcomes of patients with acute myeloid leukaemia
Q50355902Persistence of minimal residual disease assessed by multiparameter flow cytometry is highly prognostic in younger patients with acute myeloid leukemia.
Q35096486Persistent molecular remission of refractory acute myeloid leukemia with inv(16)(p13.1q22) in an elderly patient induced by cytarabine ocfosfate hydrate.
Q38154339Perspective on how to approach molecular diagnostics in acute myeloid leukemia and myelodysplastic syndromes in the era of next-generation sequencing
Q38428692Perspectives for therapeutic targeting of gene mutations in acute myeloid leukaemia with normal cytogenetics.
Q35286194Pharmacodynamics of cytarabine induced leucopenia: a retrospective cohort study
Q37386171Pharmacokinetics and dose escalation of the heat shock protein inhibitor 17-allyamino-17-demethoxygeldanamycin in combination with bortezomib in relapsed or refractory acute myeloid leukemia
Q46769583Pharmacometabolomics identifies dodecanamide and leukotriene B4 dimethylamide as a predictor of chemosensitivity for patients with acute myeloid leukemia treated with cytarabine and anthracycline
Q34754350Phase 1 and pharmacokinetic study of bolus-infusion flavopiridol followed by cytosine arabinoside and mitoxantrone for acute leukemias
Q33437309Phase 1 dose-escalation study of oral abexinostat for the treatment of patients with relapsed/refractory higher-risk myelodysplastic syndromes, acute myeloid leukemia, or acute lymphoblastic leukemia
Q89534004Phase 1 study of the MDM2 antagonist RO6839921 in patients with acute myeloid leukemia
Q53389797Phase 1 trial of linifanib (ABT-869) in patients with refractory or relapsed acute myeloid leukemia.
Q88548733Phase 1/2 trial of GCLAM with dose-escalated mitoxantrone for newly diagnosed AML or other high-grade myeloid neoplasms
Q93114776Phase 1b study of the MDM2 inhibitor AMG 232 with or without trametinib in relapsed/refractory acute myeloid leukemia
Q90642732Phase I Trial of Lithium and Tretinoin for Treatment of Relapsed and Refractory Non-promyelocytic Acute Myeloid Leukemia
Q36680199Phase I and pharmacologic trial of cytosine arabinoside with the selective checkpoint 1 inhibitor Sch 900776 in refractory acute leukemias.
Q37362705Phase I clinical study of RG7356, an anti-CD44 humanized antibody, in patients with acute myeloid leukemia
Q42417074Phase I study of evofosfamide, an investigational hypoxia-activated prodrug, in patients with advanced leukemia
Q33412609Phase I study of oral clofarabine consolidation in adults aged 60 and older with acute myeloid leukemia
Q83255595Phase I trial and pharmacokinetic study of high-dose clofarabine and busulfan and allogeneic stem cell transplantation in adults with high-risk and refractory acute leukemia
Q64915559Phase I trial of plerixafor combined with decitabine in newly diagnosed older patients with acute myeloid leukemia.
Q36467485Phase I trial of volasertib, a Polo-like kinase inhibitor, in Japanese patients with acute myeloid leukemia
Q59315342Phase II Study of Allogeneic Transplantation for Older Patients With Acute Myeloid Leukemia in First Complete Remission Using a Reduced-Intensity Conditioning Regimen: Results From Cancer and Leukemia Group B 100103 (Alliance for Clinical Trials in O
Q27852623Phase II study of the oral MEK inhibitor selumetinib in advanced acute myelogenous leukemia: a University of Chicago phase II consortium trial.
Q37282330Phase II trial of clofarabine and daunorubicin as induction therapy for acute myeloid leukemia patients greater than or equal to 60 years of age.
Q35930622Phase II trial of vorinostat and gemtuzumab ozogamicin as induction and post-remission therapy in older adults with previously untreated acute myeloid leukemia
Q92890311Phenylhexyl isothiocyanate suppresses cell proliferation and promotes apoptosis via repairing mutant P53 in human myeloid leukemia M2 cells
Q33956990Plasma cell leukemia: consensus statement on diagnostic requirements, response criteria and treatment recommendations by the International Myeloma Working Group
Q38380625Plasma cell leukemia: from biology to treatment
Q34411659Polymorphisms in XPC provide prognostic information in acute myeloid leukemia
Q35952449Polymorphisms of Dectin-1 and TLR2 Predispose to Invasive Fungal Disease in Patients with Acute Myeloid Leukemia
Q41646967Polymorphisms of Toll-like receptors (TLR2 and TLR4) are associated with the risk of infectious complications in acute myeloid leukemia
Q51395611Population pharmacokinetics of Daunorubicin in adult patients with acute myeloid leukemia.
Q41930487Post hoc analysis of the relationship between baseline white blood cell count and survival outcome in a randomized Phase III trial of decitabine in older patients with newly diagnosed acute myeloid leukemia
Q99574646Post-remission Therapy with Repeated Courses of High Dose Cytarabine, Idarubicin and Limited Autologous Stem Cell Support Achieves a Very Good Long-Term Outcome in ELN Favorable and Intermediate-Risk AML
Q26995867Post-remission therapy for acute myeloid leukemia
Q40190632Post-remission treatment with allogeneic stem cell transplantation in patients aged 60 years and older with acute myeloid leukaemia: a time-dependent analysis
Q36528379Postremission sequential monitoring of minimal residual disease by WT1 Q-PCR and multiparametric flow cytometry assessment predicts relapse and may help to address risk-adapted therapy in acute myeloid leukemia patients.
Q27851805Potential application of IDH1 and IDH2 mutations as prognostic indicators in non-promyelocytic acute myeloid leukemia: a meta-analysis
Q36797201Potential of whole-genome sequencing for determining risk and personalizing therapy: focus on AML
Q38855427Potentially avoidable hospital admissions in older patients with acute myeloid leukaemia in the USA: a retrospective analysis
Q37072126Pre- and post-transplant quantification of measurable ('minimal') residual disease via multiparameter flow cytometry in adult acute myeloid leukemia
Q64270574Pre-clinical evaluation of Minnelide as a therapy for acute myeloid leukemia
Q39474999Pre-transplantation minimal residual disease with cytogenetic and molecular diagnostic features improves risk stratification in acute myeloid leukemia
Q50883085Pre-treatment with oral hydroxyurea prior to intensive chemotherapy improves early survival of patients with high hyperleukocytosis in acute myeloid leukemia.
Q33458896Precision oncology for acute myeloid leukemia using a knowledge bank approach
Q49534332Precision therapy for acute myeloid leukemia.
Q37707078Preclinical and early clinical evaluation of the oral AKT inhibitor, MK-2206, for the treatment of acute myelogenous leukemia
Q34390721Preconditioning serum levels of endothelial cell-derived molecules and the risk of posttransplant complications in patients treated with allogeneic stem cell transplantation
Q39233284Predicting Chemotherapy Resistance in AML.
Q35343940Prediction of adverse events during intensive induction chemotherapy for acute myeloid leukemia or high-grade myelodysplastic syndromes
Q35565648Prediction of early death after induction therapy for newly diagnosed acute myeloid leukemia with pretreatment risk scores: a novel paradigm for treatment assignment
Q38448204Predictive factors for rapid neutrophil and platelet engraftment after allogenic peripheral blood stem cell transplantation in patients with acute leukemia
Q40525341Predictive significance of the European LeukemiaNet classification of genetic aberrations in patients with acute myeloid leukaemia undergoing allogeneic stem cell transplantation
Q90788426Predictors of short-term and long-term mortality in critically ill patients admitted to the intensive care unit following allogeneic stem cell transplantation
Q53626513Presence of isocitrate dehydrogenase mutations may predict clinical response to hypomethylating agents in patients with acute myeloid leukemia.
Q37270982Pretransplant NPM1 MRD levels predict outcome after allogeneic hematopoietic stem cell transplantation in patients with acute myeloid leukemia
Q41114465Pretreatment d-2-hydroxyglutarate serum levels negatively impact on outcome in IDH1-mutated acute myeloid leukemia.
Q38963204Prevalence and Prognostic Value of IDH1 R132 Mutation in Newly Diagnosed AML Egyptian Patients with Normal Karyotype.
Q33877213Primary refractory acute myeloid leukaemia - in search of better definitions and therapies
Q41528711Primetime for chemotherapy in acute myeloid leukemia
Q38244524Profile of pacritinib and its potential in the treatment of hematologic disorders
Q89170844Profiling of aberrant DNA methylation in acute myeloid leukemia reveals subclasses of CG-rich regions with epigenetic or genetic association
Q38263126Prognosis and monitoring of core-binding factor acute myeloid leukemia: current and emerging factors
Q36006412Prognosis of acute myeloid leukemia harboring monosomal karyotype in patients treated with or without allogeneic hematopoietic cell transplantation after achieving complete remission
Q26771740Prognostic Significance of KIT Mutations in Core-Binding Factor Acute Myeloid Leukemia: A Systematic Review and Meta-Analysis
Q40370775Prognostic Significance of Residual Acute Myeloid Leukemia in Bone Marrow Samples Taken Prior to Allogeneic Hematopoietic Cell Transplantation
Q65002747Prognostic Value of Genetic Alterations in Elderly Patients with Acute Myeloid Leukemia: A Single Institution Experience.
Q55003767Prognostic Value of RUNX1 Mutations in AML: A Meta-Analysis
Q35152173Prognostic and biologic significance of DNMT3B expression in older patients with cytogenetically normal primary acute myeloid leukemia
Q38183943Prognostic factors for acute myeloid leukaemia in adults--biological significance and clinical use.
Q34119417Prognostic gene mutations and distinct gene- and microRNA-expression signatures in acute myeloid leukemia with a sole trisomy 8.
Q53362481Prognostic impact of chromosomal translocations in myelodysplastic syndromes and chronic myelomonocytic leukemia patients. A study by the spanish group of myelodysplastic syndromes.
Q33558123Prognostic impact of day 15 blast clearance in risk-adapted remission induction chemotherapy for younger patients with acute myeloid leukemia: long-term results of the multicenter prospective LAM-2001 trial by the GOELAMS study group
Q36505822Prognostic impact of discordant results from cytogenetics and flow cytometry in patients with acute myeloid leukemia undergoing hematopoietic cell transplantation
Q40359787Prognostic impact of the CD34+/CD38- cell burden in patients with acute myeloid leukemia receiving allogeneic stem cell transplantation
Q87729487Prognostic impact of the European LeukemiaNet standardized reporting system in older AML patients receiving stem cell transplantation after non-myeloablative conditioning
Q37467919Prognostic impact of viral reactivations in acute myeloid leukemia patients undergoing allogeneic stem cell transplantation in first complete response
Q38289289Prognostic impact of white blood cell count in intermediate risk acute myeloid leukemia: relevance of mutated NPM1 and FLT3-ITD.
Q54355087Prognostic implications and molecular associations of NADH dehydrogenase subunit 4 (ND4) mutations in acute myeloid leukemia.
Q37817621Prognostic markers for myeloid neoplasms: a comparative review of the literature and goals for future investigation
Q36852251Prognostic markers in AML: focus on CBFL
Q50042376Prognostic relevance of DNMT3A R882 mutations in AML patients undergoing non-myeloablative conditioning hematopoietic stem cell transplantation.
Q45206762Prognostic risk score for the survival of elderly patients with acute myeloid leukaemia comprising comorbidities
Q34273628Prognostic significance of 11q23 aberrations in adult acute myeloid leukemia and the role of allogeneic stem cell transplantation
Q44000070Prognostic significance of CD56 antigen expression in patients with acute myeloid leukemia
Q34635511Prognostic significance of DNA methyltransferase 3A mutations in cytogenetically normal acute myeloid leukemia: a study by the Acute Leukemia French Association
Q27853004Prognostic significance of FLT3 internal tandem duplication, nucleophosmin 1, and CEBPA gene mutations for acute myeloid leukemia patients with normal karyotype and younger than 60 years: a systematic review and meta-analysis.
Q30248904Prognostic significance of FLT3-ITD in pediatric acute myeloid leukemia: a meta-analysis of cohort studies
Q36439908Prognostic significance of IDH1 mutations in acute myeloid leukemia: a meta-analysis
Q41847123Prognostic significance of NPM1 mutations in acute myeloid leukemia: A meta-analysis
Q38187680Prognostic significance of Tet methylcytosine dioxygenase 2 (TET2) gene mutations in adult patients with acute myeloid leukemia: a meta-analysis
Q35540475Prognostic significance of diagnosed WT1 level in acute myeloid leukemia: a meta-analysis
Q34477821Prognostic significance of expression of a single microRNA, miR-181a, in cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study
Q43599101Prognostic significance of flow cytometric residual disease, dysregulated neutrophils/monocytes, and hematogones in adult acute myeloid leukemia in first remission
Q41321988Prognostic significance of high GFI1 expression in AML of normal karyotype and its association with a FLT3-ITD signature.
Q35690315Prognostic significance of the BAALC gene expression in adult patients with acute myeloid leukemia: A meta-analysis
Q36457184Prognostic significance of the European LeukemiaNet standardized system for reporting cytogenetic and molecular alterations in adults with acute myeloid leukemia
Q37160073Prognostic significance of the Medical Research Council cytogenetic classification compared with the European LeukaemiaNet risk classification system in acute myeloid leukaemia
Q40219910Prognostic value of brain and acute leukemia cytoplasmic gene expression in egyptian children with acute myeloid leukemia
Q47805959Prognostic value of genetic mutations in adolescent and young adults with acute myeloid leukemia
Q27024006Progress in acute myeloid leukemia
Q38095115Prophylactic use of granulocyte colony-stimulating factor after consolidation therapy with high-dose cytarabine for acute myeloid leukemia
Q50928096Prospective comparison of early bone marrow evaluation on day 5 versus day 14 of the "3 + 7" induction regimen for acute myeloid leukemia.
Q35640339Protection of acute myeloid leukaemia cells from apoptosis induced by front-line chemotherapeutics is mediated by haem oxygenase-1
Q47109059Protein phosphatase 4 regulatory subunit 2 (PPP4R2) is recurrently deleted in acute myeloid leukemia and required for efficient DNA double strand break repair
Q90462212Proteome and Phosphoproteome Changes Associated with Prognosis in Acute Myeloid Leukemia
Q37427667Proven invasive pulmonary mucormycosis successfully treated with amphotericin B and surgery in patient with acute myeloblastic leukemia: a case report
Q91272581Providing both autologous and allogeneic hematopoietic stem cell transplants (HSCT) may have a stronger impact on the outcome of autologous HSCT in adult patients than activity levels or implementation of JACIE at Belgian transplant centres
Q92688206Quality of life and mood of older patients with acute myeloid leukemia (AML) receiving intensive and non-intensive chemotherapy
Q36022521Quantitative fragment analysis of FLT3-ITD efficiently identifying poor prognostic group with high mutant allele burden or long ITD length
Q64066440Quizartinib (AC220): a promising option for acute myeloid leukemia
Q42979759RB in breast cancer: differential effects in estrogen receptor-positive and estrogen receptor-negative disease
Q36036605RIC versus MAC UCBT in adults with AML: A report from Eurocord, the ALWP and the CTIWP of the EBMT
Q40531872RNA and protein expression of herpesvirus entry mediator (HVEM) is associated with molecular markers, immunity-related pathways and relapse-free survival of patients with AML.
Q27851839RUNX1 mutations are associated with poor outcome in younger and older patients with cytogenetically normal acute myeloid leukemia and with distinct gene and MicroRNA expression signatures
Q27853381RUNX1 mutations in acute myeloid leukemia are associated with distinct clinico-pathologic and genetic features
Q28597831RUNX1 truncation resulting from a cryptic and novel t(6;21)(q25;q22) chromosome translocation in acute myeloid leukemia: A case report
Q61755948Radionuclide Therapy of Leukemias and Multiple Myeloma
Q51336746Randomized comparison of fixed-schedule versus response-oriented individualized induction therapy and use of ubenimex during and after consolidation therapy for elderly patients with acute myeloid leukemia: the JALSG GML200 Study.
Q90569027Randomized comparison of low dose cytarabine with or without glasdegib in patients with newly diagnosed acute myeloid leukemia or high-risk myelodysplastic syndrome
Q36709001Randomized multicenter phase II study of flavopiridol (alvocidib), cytarabine, and mitoxantrone (FLAM) versus cytarabine/daunorubicin (7+3) in newly diagnosed acute myeloid leukemia
Q36366636Randomized phase II study of two schedules of flavopiridol given as timed sequential therapy with cytosine arabinoside and mitoxantrone for adults with newly diagnosed, poor-risk acute myelogenous leukemia
Q47730914Randomized phase II trial of cytosine arabinoside with and without the CHK1 inhibitor MK-8776 in relapsed and refractory acute myeloid leukemia
Q91387208Randomized phase-II trial evaluating induction therapy with idarubicin and etoposide plus sequential or concurrent azacitidine and maintenance therapy with azacitidine
Q64075116Randomized trial comparing standard vs sequential high-dose chemotherapy for inducing early CR in adult AML
Q60300719Randomized trial of 10 days of decitabine ± bortezomib in untreated older patients with AML: CALGB 11002 (Alliance)
Q34106830Randomized, phase 2 trial of low-dose cytarabine with or without volasertib in AML patients not suitable for induction therapy
Q89673632Rapid Donor Identification Improves Survival in High-Risk First-Remission Patients With Acute Myeloid Leukemia
Q54283212Rapid and highly specific screening for NPM1 mutations in acute myeloid leukemia.
Q44365229Rapid rate of peripheral blood blast clearance accurately predicts complete remission in acute myeloid leukemia
Q51765662Rapid remineralization of multiple disseminated bone lesions after high-dose cytarabine in a patient with isolated myeloid sarcoma.
Q33779805Ras oncogene-independent activation of RALB signaling is a targetable mechanism of escape from NRAS(V12) oncogene addiction in acute myeloid leukemia.
Q89303143Re-induction chemotherapy using FLAG-mitoxantrone for adult patients with relapsed acute leukemia: a single-center experience from United Arab Emirates
Q92441402Real-world experience with decitabine as a first-line treatment in 306 elderly acute myeloid leukaemia patients unfit for intensive chemotherapy
Q34082437Recent advances in the treatment of acute myeloid leukemia.
Q42149211Recent developments in management of older patients with acute myeloid leukemia
Q38194465Recent discoveries in molecular characterization of acute myeloid leukemia
Q34069811Recombinant interleukin-2 in patients aged younger than 60 years with acute myeloid leukemia in first complete remission: results from Cancer and Leukemia Group B 19808
Q89770340Recommendations for reporting post-transplant relapse in AML
Q28553650Redirecting Specificity of T cells Using the Sleeping Beauty System to Express Chimeric Antigen Receptors by Mix-and-Matching of VL and VH Domains Targeting CD123+ Tumors
Q38760676Reduced hematopoietic stem cell frequency predicts outcome in acute myeloid leukemia
Q33680186Reduced-intensity allogeneic hematopoietic transplantation should be considered a standard of care for older patients with acute myeloid leukemia
Q40494657Reduced-intensity conditioning with fludarabine and busulfan for allogeneic hematopoietic cell transplantation in elderly or infirm patients with advanced myeloid malignancies
Q86046493Reduced-intensity conditioning with fludarabine and thiotepa for second allogeneic transplantation of relapsed patients with AML
Q50050273Reduced-toxicity conditioning for allogeneic hematopoietic cell transplantation in elderly or comorbid patients with AML using fludarabine, BCNU and melphalan: disease stage at transplant determines outcome.
Q34463645Reduced-toxicity conditioning prior to allogeneic stem cell transplantation improves outcome in patients with myeloid malignancies
Q54350933Reduction of leukemia cell burden and restoration of normal hematopoiesis at 3 months of crizotinib treatment in RAN-binding protein 2 (RANBP2)-anaplastic lymphoma kinase (ALK) acute myeloid leukemia.
Q45394555Refining the diagnosis and prognostic categorization of acute myeloid leukemia patients with an integrated use of cytogenetic and molecular studies
Q52374880Relapse and survival after transplantation for complex karyotype acute myeloid leukemia: A report from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation and the University of Texas MD Anderson Cancer Cente
Q37611616Relationship between baseline white blood cell count and renal and hepatic function in older patients with acute myeloid leukemia
Q52770446Relationship between white blood cell count elevation and clinical response after G-CSF priming chemotherapy for acute myeloid leukemia.
Q39260268Relative mitochondrial priming of myeloblasts and normal HSCs determines chemotherapeutic success in AML
Q48305045Remissions after third induction chemotherapy for primary non-responders with acute myeloid leukemia (AML) are uncommon and short-lived.
Q53196555Renaissance of autologous stem cell transplantation for AML?
Q55076495Reporting guidelines for oncology research: helping to maximise the impact of your research.
Q53506939Reproducibility and prognostic significance of morphologic dysplasia in de novo acute myeloid leukemia.
Q34310186Requirement for CDK6 in MLL-rearranged acute myeloid leukemia
Q48272510Residual disease detection using targeted parallel sequencing predicts relapse in cytogenetically normal acute myeloid leukemia.
Q41816813Resistance of leukemia cells to cytarabine chemotherapy is mediated by bone marrow stroma, involves cell-surface equilibrative nucleoside transporter-1 removal and correlates with patient outcome
Q35054435Resistance prediction in AML: analysis of 4601 patients from MRC/NCRI, HOVON/SAKK, SWOG and MD Anderson Cancer Center.
Q38183872Response evaluation and monitoring of multiple myeloma
Q52719818Response of Myeloid Leukemia Cells to Luteolin is Modulated by Differentially Expressed Pituitary Tumor-Transforming Gene 1 (PTTG1) Oncoprotein.
Q46721176Results of a phase 1 study of quizartinib as maintenance therapy in subjects with acute myeloid leukemia in remission following allogeneic hematopoietic stem cell transplant.
Q37526840Results of treatment of acute myeloid leukemia in central part of Iran
Q36544560Revealing very small FLT3 ITD mutated clones by ultra-deep sequencing analysis has important clinical implications in AML patients
Q38270780Reversible inhibitors of LSD1 as therapeutic agents in acute myeloid leukemia: clinical significance and progress to date
Q37850824Review of the relevance of aberrant antigen expression by flow cytometry in myeloid neoplasms
Q38686515Review: Aberrant EVI1 expression in acute myeloid leukaemia
Q41906043Ring chromosome 18 abnormality in acute myelogenous leukemia: the clinical dilemma
Q55310120Risk factors for length of stay and charge per day differ between older and younger hospitalized patients with AML.
Q40971755Risk factors for outcome in refractory acute myeloid leukemia patients treated with a combination of fludarabine, cytarabine, and amsacrine followed by a reduced-intensity conditioning and allogeneic stem cell transplantation.
Q26771438Risk factors for relapse after allogeneic transplantation in acute myeloid leukemia
Q34996659Risk of marrow neoplasms after adjuvant breast cancer therapy: the national comprehensive cancer network experience
Q35781605Role of ASXL1 and TP53 mutations in the molecular classification and prognosis of acute myeloid leukemias with myelodysplasia-related changes
Q90053632Role of GFI1 in Epigenetic Regulation of MDS and AML Pathogenesis: Mechanisms and Therapeutic Implications
Q37419265Role of HOTAIR in the diagnosis and prognosis of acute leukemia
Q38352241Role of chromosomal aberrations in clonal diversity and progression of acute myeloid leukemia
Q36597388Role of natural killer cell subsets and natural cytotoxicity receptors for the outcome of immunotherapy in acute myeloid leukemia
Q90274839Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance
Q42683573Role of regulatory T cells in acute myeloid leukemia patients undergoing relapse-preventive immunotherapy
Q34144877Routine use of microarray-based gene expression profiling to identify patients with low cytogenetic risk acute myeloid leukemia: accurate results can be obtained even with suboptimal samples
Q46905468SETBP1 mutations in 658 patients with myelodysplastic syndromes, chronic myelomonocytic leukemia and secondary acute myeloid leukemias.
Q46475052SNAP-Tag Technology: A Promising Tool for Ex Vivo Immunophenotyping
Q38265472STAT3 as a possible therapeutic target in human malignancies: lessons from acute myeloid leukemia
Q101409830SYK inhibition targets acute myeloid leukemia stem cells by blocking their oxidative metabolism
Q98177136Safety and efficacy of BAY1436032 in IDH1-mutant AML: phase I study results
Q90200489Safety and efficacy of oral panobinostat plus chemotherapy in patients aged 65 years or younger with high-risk acute myeloid leukemia
Q90589522Safety and efficacy of talacotuzumab plus decitabine or decitabine alone in patients with acute myeloid leukemia not eligible for chemotherapy: results from a multicenter, randomized, phase 2/3 study
Q34060237Safety, efficacy and biological predictors of response to sequential azacitidine and lenalidomide for elderly patients with acute myeloid leukemia
Q41717987Salvage chemotherapy followed by granulocyte colony-stimulating factor-primed donor leukocyte infusion with graft-vs.-host disease control for minimal residual disease in acute leukemia/myelodysplastic syndrome after allogeneic hematopoietic stem ce
Q37216454Salvage therapy with high-dose cytarabine and mitoxantrone in combination with all-trans retinoic acid and gemtuzumab ozogamicin in acute myeloid leukemia refractory to first induction therapy
Q92519522Scalable Prediction of Acute Myeloid Leukemia Using High-Dimensional Machine Learning and Blood Transcriptomics
Q43042854Schedule- and dose-dependency of CPX-351, a synergistic fixed ratio cytarabine:daunorubicin formulation, in consolidation treatment against human leukemia xenografts
Q40542266Second allogeneic transplantation for relapse of malignant disease: retrospective analysis of outcome and predictive factors by the EBMT.
Q51735777Second haematopoietic SCT using HLA-haploidentical donors in patients with relapse of acute leukaemia after a first allogeneic transplantation.
Q39036999Second line azacitidine for elderly or infirmed patients with acute myeloid leukemia (AML) not eligible for allogeneic hematopoietic cell transplantation-a retrospective national multicenter study
Q38542828Secondary Adult Acute Myeloid Leukemia: a Review of Our Evolving Understanding of a Complex Disease Process
Q48256316Secondary acute myeloid leukaemia in elderly patients: Patient's fitness criteria and ELN prognostic stratification can be applied to guide treatment decisions. An analysis of 280 patients by the network rete ematologica lombarda (REL).
Q38349205Secondary malignancies following high dose therapy and autologous hematopoietic cell transplantation-systematic review and meta-analysis
Q28087213Secondary mutations as mediators of resistance to targeted therapy in leukemia
Q61807712Selective targeting of NAMPT by KPT-9274 in acute myeloid leukemia
Q43649404Sensitive measurement of quantity dynamics of FLT3 internal tandem duplication at early time points provides prognostic information
Q36862505Sequential azacitidine plus lenalidomide combination for elderly patients with untreated acute myeloid leukemia
Q40139200Sequential azacitidine plus lenalidomide in previously treated elderly patients with acute myeloid leukemia and higher risk myelodysplastic syndrome
Q37555840Sequential regimen of clofarabine, cytosine arabinoside and reduced-intensity conditioned transplantation for primary refractory acute myeloid leukemia
Q58733645Serotonin receptor type 1B constitutes a therapeutic target for MDS and CMML
Q36294264Serum Exosome MicroRNA as a Minimally-Invasive Early Biomarker of AML.
Q90935240Serum albumin or body mass index: Which prognostic factor for survival in patients with acute myeloblastic leukaemia?
Q54482564Severe acute GvHD following administration of ipilimumab for early relapse of AML after haploidentical stem cell transplantation.
Q55163802Sex disparity in childhood and young adult acute myeloid leukemia (AML) survival: Evidence from US population data.
Q34193514Shortcomings in the clinical evaluation of new drugs: acute myeloid leukemia as paradigm
Q36730404Significance of FAB subclassification of "acute myeloid leukemia, NOS" in the 2008 WHO classification: analysis of 5848 newly diagnosed patients
Q39062973Significance of OCT1 Expression in Acute Myeloid Leukemia.
Q37131922Significance of expression of ITGA5 and its splice variants in acute myeloid leukemia: a report from the Children's Oncology Group
Q37151698Significance of minimal residual disease before myeloablative allogeneic hematopoietic cell transplantation for AML in first and second complete remission
Q89893024Significance of minimal residual disease monitoring by real-time quantitative polymerase chain reaction in core binding factor acute myeloid leukemia for transplantation outcomes
Q35643058Significant reduction of red blood cell transfusion requirements by changing from a double-unit to a single-unit transfusion policy in patients receiving intensive chemotherapy or stem cell transplantation
Q48144263Similar outcome of allogeneic stem cell transplantation after myeloablative and sequential conditioning regimen in patients with refractory or relapsed acute myeloid leukemia: A study from the Société Francophone de Greffe de Moelle et de Thérapie C
Q53590608Single nucleotide polymorphisms of cytarabine metabolic genes influence clinical outcome in acute myeloid leukemia patients receiving high-dose cytarabine therapy.
Q37580273Smac mimetic induces cell death in a large proportion of primary acute myeloid leukemia samples, which correlates with defined molecular markers
Q37432049Somatic mutations of isocitrate dehydrogenases 1 and 2 are prognostic and follow-up markers in patients with acute myeloid leukaemia with normal karyotype
Q92668893Somatostatin receptor mediated targeting of acute myeloid leukemia by photodynamic metal complexes for light induced apoptosis
Q54113908Sorafenib Dose Recommendation in Acute Myeloid Leukemia Based on Exposure-FLT3 Relationship.
Q54363283Sorafenib plus all-trans retinoic acid for AML patients with FLT3-ITD and NPM1 mutations.
Q91920608Sorafenib plus intensive chemotherapy improves survival in patients with newly diagnosed, FLT3-internal tandem duplication mutation-positive acute myeloid leukemia
Q33598706Southwestern Oncology Group pretreatment risk criteria as predictive or prognostic factors in acute myeloid leukemia
Q54475024Specific immune responses against epitopes derived from Aurora kinase A and B in acute myeloid leukemia.
Q40125142Spectrum of mucocutaneous manifestations in an Asian cohort of patients with leukemia.
Q33394612Spotlight on histamine dihydrochloride in acute myeloid leukaemia
Q41140906Stanniocalcin1 gene expression in patients with acute leukemia: impact on response to therapy and disease outcome.
Q26765858Stem Cell Modeling of Core Binding Factor Acute Myeloid Leukemia
Q90341632Stenotrophomonas maltophilia colonization during allogeneic hematopoietic stem cell transplantation is associated with impaired survival
Q88012749Stringent or nonstringent complete remission and prognosis in acute myeloid leukemia: a Danish population-based study
Q42429593Strong impact of extramedullary involvement in high-risk AML patients with active disease receiving the FLAMSA conditioning regimen for HSCT.
Q96304648Successful Anti-CLL1 CAR T-Cell Therapy in Secondary Acute Myeloid Leukemia
Q40961845Successful haploidentical stem cell transplantation with prophylactic administration of liposomal amphotericin B after invasive pulmonary zygomycosis.
Q40170336Successful management of acute myeloid leukemia transformed from chronic myelomonocytic leukemia in the elderly by a combination regimen of decitabine and cytarabine, aclarubicin and granulocyte colony-stimulating factor: A case report
Q48025011Successful treatment of post-transplant relapsed acute myeloid leukemia with FLT3 internal tandem duplication using the combination of induction chemotherapy, donor lymphocyte infusion, sorafenib and azacitidine. Report of three cases
Q39449424Survival and cure of acute myeloid leukaemia in England, 1971-2006: a population-based study
Q98164451Survival differences and associated molecular signatures of DNMT3A-mutant acute myeloid leukemia patients
Q45042500Symptom Management and Psychosocial Needs of Adults With Acute Myeloid Leukemia During Induction Treatment: A Pilot Study.
Q38691792Symptomatic central nervous system involvement in adult patients with acute myeloid leukemia
Q42265653Synergistic killing of FLT3ITD-positive AML cells by combined inhibition of tyrosine-kinase activity and N-glycosylation
Q49780236Systematic review of health state utility values for acute myeloid leukemia.
Q37272020T cells expressing CD123-specific chimeric antigen receptors exhibit specific cytolytic effector functions and antitumor effects against human acute myeloid leukemia.
Q41138074T-replete haploidentical allogeneic transplantation using post-transplantation cyclophosphamide in advanced AML and myelodysplastic syndromes.
Q33566938TET2 and MEG3 promoter methylation is associated with acute myeloid leukemia in a Hainan population
Q27851621TET2 mutations improve the new European LeukemiaNet risk classification of acute myeloid leukemia: a Cancer and Leukemia Group B study
Q35082536TET2 mutations in secondary acute myeloid leukemias: a French retrospective study
Q89967170THBS1 Is a Novel Serum Prognostic Factors of Acute Myeloid Leukemia
Q34320769TLR9-mediated siRNA delivery for targeting of normal and malignant human hematopoietic cells in vivo
Q40245483TNF as marker of oral candidiasis, HSV infection, and mucositis onset during chemotherapy in leukemia patients.
Q27853319TP53 mutation in patients with high-risk acute myeloid leukaemia treated with allogeneic haematopoietic stem cell transplantation
Q50450550TP53 mutations and MDM2(SNP309) identify subgroups of AML patients with impaired outcome.
Q36356216TWIST-1 promotes cell growth, drug resistance and progenitor clonogenic capacities in myeloid leukemia and is a novel poor prognostic factor in acute myeloid leukemia
Q44772522Tailored central nervous system-directed treatment strategy for isolated CNS recurrence of adult acute myeloid leukemia
Q46213367Tailored temozolomide therapy according to MGMT methylation status for elderly patients with acute myeloid leukemia
Q44826618Tailoring sparse multivariable regression techniques for prognostic single-nucleotide polymorphism signatures
Q35750567Targeted Therapy of FLT3 in Treatment of AML-Current Status and Future Directions
Q47100599Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia.
Q57740688Targeted next-generation sequencing detects point mutations, insertions, deletions and balanced chromosomal rearrangements as well as identifies novel leukemia-specific fusion genes in a single procedure
Q47965108Targeted therapies in Acute Myeloid Leukemia: a focus on FLT-3 inhibitors and ABT199.
Q64901561Targeted therapies in the treatment of adult acute myeloid leukemias: current status and future perspectives.
Q33829283Targeting CD157 in AML using a novel, Fc-engineered antibody construct
Q61815346Targeting FLT3 mutations in AML: review of current knowledge and evidence
Q52375473Targeting Leukemia Stem Cells in the Bone Marrow Niche.
Q48166242Targeting Ras signaling in AML: RALB is a small GTPase with big potential.
Q44489428Targeting apoptosis in acute myeloid leukaemia
Q37662400Targeting binding partners of the CBFβ-SMMHC fusion protein for the treatment of inversion 16 acute myeloid leukemia
Q38606849Targeting of cell metabolism in human acute myeloid leukemia--more than targeting of isocitrate dehydrogenase mutations and PI3K/AKT/mTOR signaling?
Q37994256Targeting of polo-like kinases and their cross talk with Aurora kinases--possible therapeutic strategies in human acute myeloid leukemia?
Q36410157Terminal myeloid differentiation in vivo is induced by FLT3 inhibition in FLT3/ITD AML.
Q37641783Tetraspanin CD81 is an adverse prognostic marker in acute myeloid leukemia.
Q94603012The 100 Most Cited Papers About Cancer Epigenetics
Q57787339The Assessment of Left Ventricle Function and Subclinical Atherosclerosis in Patients with Acute Myeloid Leukemia
Q42024644The Challenge of AML in Older Patients
Q43754303The EBMT activity survey 2008: impact of team size, team density and new trends
Q28830861The European Hematology Association Roadmap for European Hematology Research: a consensus document
Q38040708The European LeukemiaNet AML Working Party consensus statement on allogeneic HSCT for patients with AML in remission: an integrated-risk adapted approach
Q34451619The European LeukemiaNet: achievements and perspectives
Q33431584The European Medicines Agency Review of Decitabine (Dacogen) for the Treatment of Adult Patients With Acute Myeloid Leukemia: Summary of the Scientific Assessment of the Committee for Medicinal Products for Human Use.
Q64085660The Expression of the SLIT-ROBO Family in Adult Patients with Acute Myeloid Leukemia
Q34555386The Future of Targeting FLT3 Activation in AML.
Q43070849The Impact of FLT3 Mutations on the Development of Acute Myeloid Leukemias
Q89457595The M2 macrophage marker CD206: a novel prognostic indicator for acute myeloid leukemia
Q36591431The MLL partial tandem duplication in adults aged 60 years and older with de novo cytogenetically normal acute myeloid leukemia
Q95314923The Novel Phospholipid Mimetic KPC34 Is Highly Active Against Acute Myeloid Leukemia with Activated Protein Kinase C
Q34766817The Prognostic Relevance of BAALC and ERG Expression Levels in Cytogenetically Normal Pediatric Acute Myeloid Leukemia.
Q47804815The Prognostic Significance of Measurable ("Minimal") Residual Disease in Acute Myeloid Leukemia.
Q37401343The Prognostic Significance of Soluble Urokinase Plasminogen Activator Receptor in Acute Myeloid Leukemia
Q52603735The Synonymous Isocitrate Dehydrogenase 1 315C>T SNP Confers an Adverse Prognosis in Egyptian Adult Patients with NPM1-/CEBPA-Negative Acute Myeloid Leukemia.
Q40872029The addition of gemtuzumab ozogamicin to chemotherapy in adult patients with acute myeloid leukemia
Q94299762The application of an integrated clinical, cytogenetic, and molecular risk stratification for acute myeloid leukemia patients using a central laboratory in a Brazilian multicentric study
Q26853348The cell biology of disease: Acute promyelocytic leukemia, arsenic, and PML bodies
Q41264435The clinical significance of negative flow cytometry immunophenotypic results in a morphologically scored positive bone marrow in patients following treatment for acute myeloid leukemia
Q27014790The clinically relevant pharmacogenomic changes in acute myelogenous leukemia
Q37153361The combination of valproic acid, all-trans retinoic acid and low-dose cytarabine as disease-stabilizing treatment in acute myeloid leukemia
Q50934618The constitutive protease release by primary human acute myeloid leukemia cells.
Q86999665The demarcation between younger and older acute myeloid leukemia patients: a pooled analysis of 3 prospective studies
Q54273037The detection of KIT mutations in acute myeloid leukemia.
Q45095746The development and validation of a decision-analytic model representing the full disease course of acute myeloid leukemia
Q38482005The diagnostic and clinical impact of genetics and epigenetics in acute myeloid leukemia
Q40356364The dual epigenetic role of PRMT5 in acute myeloid leukemia: gene activation and repression via histone arginine methylation
Q24187297The effects of idarubicin versus other anthracyclines for induction therapy of patients with newly diagnosed leukaemia
Q34524753The efficacy of the ribonucleotide reductase inhibitor Didox in preclinical models of AML.
Q21284742The epigenetic landscape of acute myeloid leukemia
Q37576054The evolving challenge of therapy-related myeloid neoplasms
Q36254225The expression level of BAALC-associated microRNA miR-3151 is an independent prognostic factor in younger patients with cytogenetic intermediate-risk acute myeloid leukemia.
Q41141719The fate of patients with acute myeloid leukemia not undergoing induction chemotherapy.
Q40827250The fludarabine, cytarabine, and granulocyte colony-stimulating factor (FLAG) chemotherapy regimen is an alternative to anthracycline-based therapy for the treatment of acute myeloid leukemia for patients with pre-existing cardiac disease.
Q36564944The human organic cation transporter OCT1 mediates high affinity uptake of the anticancer drug daunorubicin
Q40279088The hypomorphic TERT A1062T variant is associated with increased treatment-related toxicity in acute myeloid leukemia
Q89776845The impact of HLA matching on outcomes of unmanipulated haploidentical HSCT is modulated by GVHD prophylaxis
Q34798476The impact of TNF superfamily molecules on overall survival in acute myeloid leukaemia: correlation with biological and clinical features.
Q48255430The importance of FLT3 mutational analysis in acute myeloid leukemia.
Q30316611The indications for allogeneic stem cell transplantation in myeloid malignancies
Q35691397The influence of cytidine deaminase -33delC polymorphism on treatment outcome with high-dose cytarabine in Chinese patients with relapsed acute myeloid leukaemia
Q88551181The influence of mutational status and biological characteristics of acute myeloid leukemia on xenotransplantation outcomes in NOD SCID gamma mice
Q34156754The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia
Q36544646The lincRNA HOTAIRM1, located in the HOXA genomic region, is expressed in acute myeloid leukemia, impacts prognosis in patients in the intermediate-risk cytogenetic category, and is associated with a distinctive microRNA signature.
Q50044511The molecular signature of AML with increased ALDH activity suggests a stem cell origin.
Q36619678The myth of the second remission of acute leukemia in the adult
Q92088455The prevalence, risk factors, and prognostic value of anxiety and depression in refractory or relapsed acute myeloid leukemia patients of North China
Q27693865The prognostic and functional role of microRNAs in acute myeloid leukemia
Q35528622The prognostic impact of germline 46/1 haplotype of Janus kinase 2 in cytogenetically normal acute myeloid leukemia.
Q43566991The prognostic relevance of miR-212 expression with survival in cytogenetically and molecularly heterogeneous AML.
Q40876342The prognostic value of hematogones in patients with acute myeloid leukemia
Q89676365The prognostic value of standardized phase angle in adults with acute leukemia: A prospective study
Q38211084The role of inflammation in leukaemia
Q83363712The role of minor subpopulations within the leukemic blast compartment of AML patients at initial diagnosis in the development of relapse
Q37924989The role of molecular genetic analysis within the diagnostic haemato-oncology laboratory
Q39027087The role of the proteasome in AML.
Q35148107The role of therapeutic leukapheresis in hyperleukocytotic AML.
Q38760822The safety of treatment options for elderly people with acute myeloid leukemia
Q44804404The state of the union on treatment of acute myeloid leukemia
Q35673578The treatment of elderly patients with acute myeloid leukemia
Q38481997The utility of next-generation sequencing in diagnosis and monitoring of acute myeloid leukemia and myelodysplastic syndromes
Q36866323The value of molecular stratification for CEBPA(DM) and NPM1(MUT) FLT3(WT) genotypes in older patients with acute myeloid leukaemia
Q41844705Therapeutic Options for Patients who are not Eligible for Intensive Chemotherapy
Q28071427Therapeutic Resistance in Acute Myeloid Leukemia: The Role of Non-Coding RNAs
Q37410557Therapeutic antagonists of microRNAs deplete leukemia-initiating cell activity
Q37372832Therapy of core binding factor acute myeloid leukemia: incremental improvements toward better long-term results
Q38603374Therapy-related acute myeloid leukemia following radioactive iodine treatment for thyroid cancer
Q37699158Therapy-related acute myeloid leukemia following treatment of lymphoid malignancies
Q28071318Therapy-related myeloid neoplasms - what have we learned so far?
Q35717790Therapy-related myeloid neoplasms following treatment with radioiodine
Q30240431Therapy-related myeloid neoplasms: does knowing the origin help to guide treatment?
Q28386366Therapy-related myeloid neoplasms: pathobiology and clinical characteristics
Q34121354Thioredoxin-1 inhibitor PX-12 induces human acute myeloid leukemia cell apoptosis and enhances the sensitivity of cells to arsenic trioxide
Q48179574Time to response and survival in hypomethylating agent-treated acute myeloid leukemia
Q49840237Timed sequential therapy for acute myelogenous leukemia: Results of a retrospective study of 301 patients and review of the literature.
Q41879404To transplant or not to transplant for adult acute myeloid leukemia: an ever-evolving decision
Q38104287To transplant or not: a dilemma for treatment of elderly AML patients in the twenty-first century
Q90177565Toll-like receptor 7/8-matured RNA-transduced dendritic cells as post-remission therapy in acute myeloid leukaemia: results of a phase I trial
Q48568919Toward a better management of older patients with acute myeloid leukemia.
Q40705792Transfusion dependency at diagnosis and transfusion intensity during initial chemotherapy are associated with poorer outcomes in adult acute myeloid leukemia
Q33440695Translational Modeling of Drug-Induced Myelosuppression and Effect of Pretreatment Myelosuppression for AZD5153, a Selective BRD4 Inhibitor
Q38235586Translational implications of somatic genomics in acute myeloid leukaemia.
Q38419355Transplant outcomes of the triple-negative NPM1/FLT3-ITD/CEBPA mutation subgroup are equivalent to those of the favourable ELN risk group, but significantly better than the intermediate-I risk group after allogeneic transplant in normal-karyotype AM
Q89777137Treated secondary acute myeloid leukemia: a distinct high-risk subset of AML with adverse prognosis
Q83834636Treatment and prophylaxis of hematologic malignancy in the central nervous system
Q26799609Treatment of Acute Myeloid Leukemia in Adolescent and Young Adult Patients
Q35591409Treatment of CD33-directed chimeric antigen receptor-modified T cells in one patient with relapsed and refractory acute myeloid leukemia
Q39112940Treatment of Elderly Patients With Acute Myeloid Leukemia
Q39263229Treatment of de novo acute myeloid leukemia in the United States: a report from the Patterns of Care program.
Q82735483Treatment of older patients with acute myeloid leukaemia
Q47796166Treatment patterns and comparative effectiveness in elderly acute myeloid leukemia patients (age 70 years or older): the Lyon-university hospital experience
Q41564670Treatment strategies in patients with AML or high-risk myelodysplastic syndrome relapsed after Allo-SCT.
Q40727176Treatment, trial participation and survival in adult acute myeloid leukemia: a population-based study in the Netherlands, 1989-2012.
Q90671631Treosulfan or busulfan plus fludarabine as conditioning treatment before allogeneic haemopoietic stem cell transplantation for older patients with acute myeloid leukaemia or myelodysplastic syndrome (MC-FludT.14/L): a randomised, non-inferiority, ph
Q38782715Tunneling nanotube (TNT) formation is downregulated by cytarabine and NF-κB inhibition in acute myeloid leukemia (AML).
Q38552664Twist as a new prognostic marker in hematological malignancies.
Q44890063Type and location of isocitrate dehydrogenase mutations influence clinical characteristics and disease outcome of acute myeloid leukemia
Q26751011Underground Adaptation to a Hostile Environment: Acute Myeloid Leukemia vs. Natural Killer Cells
Q37865545Unfavorable-risk cytogenetics in acute myeloid leukemia
Q35885311Unique dual targeting of thymidylate synthase and topoisomerase1 by FdUMP[10] results in high efficacy against AML and low toxicity
Q54212475Unmanipulated haploidentical in comparison with matched unrelated donor stem cell transplantation in patients 60 years and older with acute myeloid leukemia: a comparative study on behalf of the ALWP of the EBMT.
Q40199108Unrelated bone marrow transplantation or immediate umbilical cord blood transplantation for patients with acute myeloid leukemia in first complete remission.
Q36125603Unrelated cord blood transplantation for adult patients with acute myeloid leukemia: higher incidence of acute graft-versus-host disease and lower survival in male patients transplanted with female unrelated cord blood--a report from Eurocord, the A
Q36951705Unrelated donor allogeneic transplantation after failure of autologous transplantation for acute myelogenous leukemia: a study from the center for international blood and marrow transplantation research
Q48272424Unrelated matched versus autologous transplantation in adult patients with good and intermediate risk acute myelogenous leukemia in first molecular remission.
Q35849255Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML.
Q41894404Update on optimal management of acute myeloid leukemia
Q26749006Use of Flow Cytometry in Clinical Practice
Q26784052Use of molecular markers to determine postremission treatment in acute myeloid leukemia with normal cytogenetics
Q28390558Use of single nucleotide polymorphism array technology to improve the identification of chromosomal lesions in leukemia
Q35198983Utility of transmission electron microscopy in small round cell tumors
Q63213733Utilization Management of Genetic Testing
Q90776364Validation and refinement of the revised 2017 European LeukemiaNet genetic risk stratification of acute myeloid leukemia
Q53275620Validation of 2 Prognostic Models in Hospitalized Patients With Advanced Hematological Malignancies in Japan.
Q38760619Validation of risk stratification models in acute myeloid leukemia using sequencing-based molecular profiling.
Q90304391Validation of the 2017 European LeukemiaNet classification for acute myeloid leukemia with NPM1 and FLT3-internal tandem duplication genotypes
Q37422385Validation of the EBMT Risk Score for South Brazilian Patients Submitted to Allogeneic Hematopoietic Stem Cell Transplantation.
Q95942095Validation of the Functional Assessment of Cancer Therapy-Leukemia instrument in patients with acute myeloid leukemia who are not candidates for intensive therapy
Q36161529Value of Different Comorbidity Indices for Predicting Outcome in Patients with Acute Myeloid Leukemia
Q40274934Vancomycin-resistant enterococci in acute myeloid leukemia and myelodysplastic syndrome patients undergoing induction chemotherapy with idarubicin and cytarabine
Q47660404Variable outcome and methylation status according to CEBPA mutant type in double-mutated acute myeloid leukemia patients and the possible implications for treatment
Q37955710Vascular access devices in leukemia: a retrospective review amongst patients treated at the Ottawa Hospital with induction chemotherapy for acute leukemia
Q26801131Volasertib for AML: clinical use and patient consideration
Q38221687Volasertib for the treatment of acute myeloid leukemia: a review of preclinical and clinical development
Q37824712Vorinostat in acute myeloid leukemia and myelodysplastic syndromes
Q39342733Vosaroxin in relapsed/refractory acute myeloid leukemia: efficacy and safety in the context of the current treatment landscape
Q36770191Vosaroxin plus cytarabine versus placebo plus cytarabine in patients with first relapsed or refractory acute myeloid leukaemia (VALOR): a randomised, controlled, double-blind, multinational, phase 3 study
Q39416207Vosaroxin: a new valuable tool with the potential to replace anthracyclines in the treatment of AML?
Q39116969What Is the Best Daunorubicin Dose and Schedule for Acute Myeloid Leukemia Induction?
Q40250091What Is the Clinical Utility of Repeat SNP Array Testing in the Follow-up of Myeloid Neoplasms?: A Retrospective Analysis of 44 Patients With Serial SNP Arrays
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Q90028979When to obtain genomic data in acute myeloid leukemia (AML) and which mutations matter
Q52684796Widespread use of measurable residual disease in acute myeloid leukemia practice.
Q54367385Wilms' tumor gene 1 expression: an independent acute leukemia prognostic indicator following allogeneic hematopoietic SCT.
Q26998971You eat what you are: autophagy inhibition as a therapeutic strategy in leukemia
Q42265722ZNF521 sustains the differentiation block in MLL-rearranged acute myeloid leukemia.
Q53365037[Acute leukemia in adults].
Q86954339[Acute myeloid leukemia]
Q49817229[Allogeneic hematopoietic stem cell transplantation for treatment of refractory and relapsed acute myeloid leukemia: outcomes and prognostic factors].
Q53059589[Analyses of outcome and prognostic factors of adult acute myeloid leukemia patients received autologous hematopoietic stem cell transplantation].
Q91911514[Cancer patients in operative intensive care medicine]
Q49722419[Cancer patients in operative intensive care medicine].
Q53961483[Chinese guidelines for diagnosis and treatment of adult acute myeloid leukemia (not APL) (2017)].
Q89097370[Clinical characteristics and prognosis of 35 patients with therapy-related hematological neoplasms]
Q53550519[Comparison of 10 mg/m² or 8 mg/m² idarubicin plus cytarabine regimen as induction chemotherapy for adult patients with newly diagnosed acute myeloid leukemia].
Q49817238[Efficacy and safety of IA regimen containing different doses of idarubicin in de-novo acute myeloid leukemia for adult patients].
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Q53138689[Long-term outcomes of homoharringtonine, cytarabine, daunorubicin or idarubicin (HAD/HAI) as induction chemotherapy in de novo acute myeloid leukemia].
Q52889701[Possibilities and limitations of stratified medicine based on biomarkers and targeted therapies in oncology].
Q50737628[Prognostic significance of blood count at the time of achieving morphologic leukemia-free state in adults with acute myeloid leukemia].
Q50882260[Prognostic significance of early assessment of minimal residual disease in acute myeloid leukemia with mutated NPM1 patients].
Q83629936[Risk-adapted therapy in acute myeloid leukemia]
Q49792052[The study of expression and prognostic value of CD123 in acute myeloid leukemia bone marrow blasts].
Q56962214acute myeloid leukemia: are we always dealing with a high-risk disease?
Q42722748inv(16) and NPM1mut AMLs engraft human cytokine knock-in mice
Q38871451lncRNA co-expression network model for the prognostic analysis of acute myeloid leukemia
Q35837541miR-10a is aberrantly overexpressed in Nucleophosmin1 mutated acute myeloid leukaemia and its suppression induces cell death.
Q92715065miR-126 promotes the growth and proliferation of leukemia stem cells by targeting DNA methyltransferase 1
Q89574008miR-196b target screen reveals mechanisms maintaining leukemia stemness with therapeutic potential
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Q48336259miR-9 is a tumor suppressor in pediatric AML with t(8;21).
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