Expression and prognostic impact of lncRNAs in acute myeloid leukemia

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Expression and prognostic impact of lncRNAs in acute myeloid leukemia is …
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scholarly articleQ13442814

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P819ADS bibcode2014PNAS..11118679G
P356DOI10.1073/PNAS.1422050112
P932PMC publication ID4284555
P698PubMed publication ID25512507
P5875ResearchGate publication ID273956724

P50authorClara D. BloomfieldQ4793409
Carlo Maria CroceQ640381
James S BlachlyQ55445072
Guido MarcucciQ66370794
Krzysztof MrózekQ66385542
Jessica KohlschmidtQ66411780
John C. ByrdQ66429603
Pearlly YanQ89625737
Jonathan E KolitzQ90696849
Meir WetzlerQ96067562
Michael A CaligiuriQ97333782
William G BlumQ98243202
Deedra Rae NicoletQ110818080
Ramiro GarzonQ114413063
Donna BucciQ114413077
Bayard L PowellQ114413078
Stefano VoliniaQ28324641
Thomas CarterQ40548426
Ann-Kathrin EisfeldQ43376244
P2093author name stringRichard M Stone
Andrew J Carroll
Maria R Baer
Joseph O Moore
Dimitrios Papaioannou
P2860cites workLong non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasisQ24607308
The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expressionQ24608592
Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosminQ24652323
MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemiaQ24655915
A myelopoiesis-associated regulatory intergenic noncoding RNA transcript within the human HOXA clusterQ24657435
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAsQ24673619
Mutations and treatment outcome in cytogenetically normal acute myeloid leukemiaQ27851430
Age-related risk profile and chemotherapy dose response in acute myeloid leukemia: a study by the German Acute Myeloid Leukemia Cooperative GroupQ27851459
Gene mutations and response to treatment with all-trans retinoic acid in elderly patients with acute myeloid leukemia. Results from the AMLSG Trial AML HD98B.Q27851460
Favorable prognostic impact of NPM1 mutations in older patients with cytogenetically normal de novo acute myeloid leukemia and associated gene- and microRNA-expression signatures: a Cancer and Leukemia Group B studyQ27851545
TET2 mutations improve the new European LeukemiaNet risk classification of acute myeloid leukemia: a Cancer and Leukemia Group B studyQ27851621
ASXL1 mutations identify a high-risk subgroup of older patients with primary cytogenetically normal AML within the ELN Favorable genetic categoryQ27851679
Age-related prognostic impact of different types of DNMT3A mutations in adults with primary cytogenetically normal acute myeloid leukemiaQ27851713
RUNX1 mutations are associated with poor outcome in younger and older patients with cytogenetically normal acute myeloid leukemia and with distinct gene and MicroRNA expression signaturesQ27851839
Acute myeloid leukemia in the elderly: assessment of multidrug resistance (MDR1) and cytogenetics distinguishes biologic subgroups with remarkably distinct responses to standard chemotherapy. A Southwest Oncology Group studyQ73292530
Results of intensive chemotherapy in 998 patients age 65 years or older with acute myeloid leukemia or high-risk myelodysplastic syndrome: predictive prognostic models for outcomeQ82366072
Wilms' tumor protein and FLT3-internal tandem duplication expression in patients with de novo acute myeloid leukemiaQ83304136
Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNetQ29012757
RNA maps reveal new RNA classes and a possible function for pervasive transcriptionQ29614334
MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancerQ29620125
A new lncRNA, APTR, associates with and represses the CDKN1A/p21 promoter by recruiting polycomb proteinsQ30413762
Targeting microRNAs in cancer: rationale, strategies and challengesQ34141089
FLT3 internal tandem duplication associates with adverse outcome and gene- and microRNA-expression signatures in patients 60 years of age or older with primary cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B studyQ34310561
BAALC and ERG expression levels are associated with outcome and distinct gene and microRNA expression profiles in older patients with de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B studyQ34541748
Cytogenetics and age are major determinants of outcome in intensively treated acute myeloid leukemia patients older than 60 years: results from AMLSG trial AML HD98-B.Q34569095
Amplification of PVT1 contributes to the pathophysiology of ovarian and breast cancer.Q34696246
MicroRNA expression in cytogenetically normal acute myeloid leukemiaQ34775265
Prognostic and biologic significance of DNMT3B expression in older patients with cytogenetically normal primary acute myeloid leukemiaQ35152173
Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: are we ready for a prognostically prioritized molecular classification?Q35615901
Low expression of MN1 associates with better treatment response in older patients with de novo cytogenetically normal acute myeloid leukemiaQ35794120
Pretreatment cytogenetics add to other prognostic factors predicting complete remission and long-term outcome in patients 60 years of age or older with acute myeloid leukemia: results from Cancer and Leukemia Group B 8461.Q35849784
miR-3151 interplays with its host gene BAALC and independently affects outcome of patients with cytogenetically normal acute myeloid leukemiaQ36100455
HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer.Q36357062
Central review of cytogenetics is necessary for cooperative group correlative and clinical studies of adult acute leukemia: the Cancer and Leukemia Group B experienceQ36713551
Acute myeloid leukemia and myelodysplastic syndromes in older patientsQ36815566
Knockdown of long non-coding RNA HOTAIR suppresses tumor invasion and reverses epithelial-mesenchymal transition in gastric cancerQ37001515
Clinical role of microRNAs in cytogenetically normal acute myeloid leukemia: miR-155 upregulation independently identifies high-risk patientsQ37065843
lincRNAs: genomics, evolution, and mechanismsQ37584905
Mutations in nucleophosmin (NPM1) in acute myeloid leukemia (AML): association with other gene abnormalities and previously established gene expression signatures and their favorable prognostic significanceQ38321981
Increased expression of the long non-coding RNA UCA1 in tongue squamous cell carcinomas: a possible correlation with cancer metastasisQ39044266
Amplification of PVT-1 is involved in poor prognosis via apoptosis inhibition in colorectal cancersQ39066542
Long non-coding RNA UCA1a(CUDR) promotes proliferation and tumorigenesis of bladder cancerQ39350395
Large intervening non-coding RNA HOTAIR is associated with hepatocellular carcinoma progressionQ39404230
Alternately spliced WT1 antisense transcripts interact with WT1 sense RNA and show epigenetic and splicing defects in cancerQ40189832
Co-resistance to retinoic acid and TRAIL by insertion mutagenesis into RAM.Q40322576
Vaults are up-regulated in multidrug-resistant cancer cell linesQ44110027
Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers.Q51856604
Antisense WT1 transcription parallels sense mRNA and protein expression in fetal kidney and can elevate protein levels in vitro.Q52182053
P433issue52
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
P304page(s)18679-18684
P577publication date2014-12-15
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleExpression and prognostic impact of lncRNAs in acute myeloid leukemia
P478volume111

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cites work (P2860)
Q91669258A 10-Long Non-Coding RNA-Based Expression Signature as a Potential Biomarker for Prognosis of Acute Myeloid Leukemia
Q89777231A 4-lncRNA scoring system for prognostication of adult myelodysplastic syndromes
Q100407536A Nuclear Long Non-Coding RNA LINC00618 Accelerates Ferroptosis in a Manner Dependent upon Apoptosis
Q64082752A critical regulator of Bcl2 revealed by systematic transcript discovery of lncRNAs associated with T-cell differentiation
Q38695117A four-gene LincRNA expression signature predicts risk in multiple cohorts of acute myeloid leukemia patients.
Q38882922A novel long noncoding RNA LINC01133 is upregulated in lung squamous cell cancer and predicts survival
Q89100184A three‑lncRNA signature for prognosis prediction of acute myeloid leukemia in patients
Q94526828Aberrant LncRNA Expression in Leukemia
Q31147507Acfs: accurate circRNA identification and quantification from RNA-Seq data
Q39400164Acute myeloid leukaemia genomics.
Q52431745An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance.
Q35731376An international data set for CMML validates prognostic scoring systems and demonstrates a need for novel prognostication strategies.
Q38804181Annotating Function to Differentially Expressed LincRNAs in Myelodysplastic Syndrome Using a Network-Based Method
Q30490446Association of a cytarabine chemosensitivity related gene expression signature with survival in cytogenetically normal acute myeloid leukemia
Q36210927C/EBPα-p30 protein induces expression of the oncogenic long non-coding RNA UCA1 in acute myeloid leukemia
Q37089402Chimeric mitochondrial peptides from contiguous regular and swinger RNA.
Q91883638Circular RNAs in leukemia
Q47134666Circular RNAs of the nucleophosmin (NPM1) gene in acute myeloid leukemia
Q26749533Clinical significance of microRNAs in chronic and acute human leukemia
Q37628972Co-expression analysis identifies long noncoding RNA SNHG1 as a novel predictor for event-free survival in neuroblastoma
Q36000584Differential Expression of Long Noncoding RNAs between Sperm Samples from Diabetic and Non-Diabetic Mice
Q49856822Differentially expressed host long intergenic noncoding RNA and mRNA in HIV-1 and HIV-2 infection.
Q92435023Emerging role of long non-coding RNAs in normal and malignant hematopoiesis
Q94475911Epigenetic landscape analysis of lncRNAs in acute myeloid leukemia with DNMT3A mutations
Q37721277Evolution of Nucleotide Punctuation Marks: From Structural to Linear Signals
Q92284294Expression and functional relevance of long non-coding RNAs in acute myeloid leukemia stem cells
Q55365672Expression levels of long non-coding RNAs are prognostic for AML outcome.
Q30275293Expression of lncRNAs in Low-Grade Gliomas and Glioblastoma Multiforme: An In Silico Analysis
Q47343750Expression profile analysis of long noncoding RNA in Acute Myeloid Leukemia by microarray and bioinformatics.
Q89238692Gene Regulatory Network Perturbation by Genetic and Epigenetic Variation
Q53190281Genome-wide characterization of lncRNAs in acute myeloid leukemia.
Q38697273High expression of CPNE3 predicts adverse prognosis in acute myeloid leukemia.
Q64261228Incorporation of long non-coding RNA expression profile in the 2017 ELN risk classification can improve prognostic prediction of acute myeloid leukemia patients
Q28821250Intronless WNT10B-short variant underlies new recurrent allele-specific rearrangement in acute myeloid leukaemia
Q36309654Large-scale gene network analysis reveals the significance of extracellular matrix pathway and homeobox genes in acute myeloid leukemia: an introduction to the Pigengene package and its applications
Q90341915LncRNA MAGI2-AS3 inhibits the self-renewal of leukaemic stem cells by promoting TET2-dependent DNA demethylation of the LRIG1 promoter in acute myeloid leukaemia
Q36018337LncRNA NALT interaction with NOTCH1 promoted cell proliferation in pediatric T cell acute lymphoblastic leukemia
Q37501589Long Intergenic Noncoding RNA 00511 Acts as an Oncogene in Non-small-cell Lung Cancer by Binding to EZH2 and Suppressing p57.
Q89113096Long Non-Coding RNA SPRY4-IT1 Can Predict Poor Prognosis in Digestive System Malignancies: a Meta-Analysis
Q64275121Long Non-Coding RNA and Acute Leukemia
Q38450930Long Non-Coding RNAs: New Players in Hematopoiesis and Leukemia
Q90403271Long Non-coding RNAs as Functional and Structural Chromatin Modulators in Acute Myeloid Leukemia
Q92060295Long Noncoding RNA SOCS2-AS Promotes Leukemogenesis in FLT3-ITD+ Acute Myeloid Leukemia Through miRNA-221
Q95267274Long Noncoding RNA H19 Facilitates Small Cell Lung Cancer Tumorigenesis Through miR-140-5p/FGF9 Axis
Q53219055Long non-coding RNA CCAL regulates colorectal cancer progression by activating Wnt/β-catenin signalling pathway via suppression of activator protein 2α.
Q53636125Long non-coding RNA GAS5 polymorphism predicts a poor prognosis of acute myeloid leukemia in Chinese patients via affecting hematopoietic reconstitution.
Q38874356Long non-coding RNA HOTAIR modulates c-KIT expression through sponging miR-193a in acute myeloid leukemia
Q92993245Long non-coding RNA HOXB-AS3 promotes myeloid cell proliferation and its higher expression is an adverse prognostic marker in patients with acute myeloid leukemia and myelodysplastic syndrome
Q37588369Long non-coding RNA NEAT1 promotes non-small cell lung cancer progression through regulation of miR-377-3p-E2F3 pathway.
Q90729138Long non-coding RNA SNHG1 indicates poor prognosis and facilitates disease progression in acute myeloid leukemia
Q60909314Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia
Q64922153Long non-coding RNAs in hematopoietic regulation.
Q28070169Long non-coding RNAs in normal and malignant hematopoiesis
Q42341694Long non-coding RNAs: another brick in the wall of normal karyotype acute myeloid leukemia?
Q38766067Long noncoding RNA PVT1 promotes cervical cancer progression through epigenetically silencing miR-200b
Q64929485Long noncoding RNA PVT1: potential oncogene in the development of acute lymphoblastic leukemia.
Q35895721Long noncoding RNA derived from CD244 signaling epigenetically controls CD8+ T-cell immune responses in tuberculosis infection
Q38698012Long noncoding RNA expression profile in cytogenetically normal acute myeloid leukemia identifies a distinct signature and a new biomarker in NPM1-mutated patients
Q46191604Long noncoding RNAs in hematopoietic malignancies
Q28077492Long noncoding RNAs: pivotal regulators in acute myeloid leukemia
Q38434466Microarray profiling and co-expression network analysis of the lncRNAs and mRNAs associated with acute leukemia in adults.
Q58573068Molecular Moirai: Long Noncoding RNA Mediators of HSC Fate
Q92996721Not Only Mutations Matter: Molecular Picture of Acute Myeloid Leukemia Emerging from Transcriptome Studies
Q36261877Over-expression of lncRNA DANCR is associated with advanced tumor progression and poor prognosis in patients with colorectal cancer
Q36771874Overexpression of ATP1B1 predicts an adverse prognosis in cytogenetically normal acute myeloid leukemia
Q64929300Overexpression of ZEB2-AS1 lncRNA is associated with poor clinical outcomes in acute myeloid leukemia.
Q41018434Overexpression of long non-coding RNA zinc finger antisense 1 in acute myeloid leukemia cell lines influences cell growth and apoptosis
Q92133424Overexpression of long noncoding RNA HOXB-AS3 indicates an unfavorable prognosis and promotes tumorigenesis in epithelial ovarian cancer via Wnt/β-catenin signaling pathway
Q36259132Overexpression of the long non-coding RNA PVT1 is correlated with leukemic cell proliferation in acute promyelocytic leukemia.
Q38428692Perspectives for therapeutic targeting of gene mutations in acute myeloid leukaemia with normal cytogenetics.
Q58781904Potential role of LINC00996 in colorectal cancer: a study based on data mining and bioinformatics
Q42396879Potential role of lncRNA cyp2c91-protein interactions on diseases of the immune system.
Q58742926Prediction of candidate RNA signatures for recurrent ovarian cancer prognosis by the construction of an integrated competing endogenous RNA network
Q92524019Prognostic and Biologic Relevance of Clinically Applicable Long Noncoding RNA Profiling in Older Patients with Cytogenetically Normal Acute Myeloid Leukemia
Q38377189Prognostic and biologic significance of long non-coding RNA profiling in younger adults with cytogenetically normal acute myeloid leukemia
Q38769960Prognostic and biological significance of the proangiogenic factor EGFL7 in acute myeloid leukemia
Q28069144Prognostic value of RDW in cancers: a systematic review and meta-analysis
Q97644946Rapid preliminary purity evaluation of tumor biopsies using deep learning approach
Q61810422Role of long non-coding RNAs in disease progression of early stage unmutated chronic lymphocytic leukemia
Q64284722Role of microRNAs, circRNAs and long noncoding RNAs in acute myeloid leukemia
Q92519522Scalable Prediction of Acute Myeloid Leukemia Using High-Dimensional Machine Learning and Blood Transcriptomics
Q89966216Systematic Nucleotide Exchange Analysis of ESTs From the Human Cancer Genome Project Report: Origins of 347 Unknown ESTs Indicate Putative Transcription of Non-Coding Genomic Regions
Q90293326The Nefarious Nexus of Noncoding RNAs in Cancer
Q58694197The Network of Non-coding RNAs in Cancer Drug Resistance
Q92137481The Regulatory Roles of Long Noncoding RNAs in Acute Myeloid Leukemia
Q50129316The Significance of Long Non-coding RNA HULC in Predicting Prognosis and Metastasis of Cancers: a Meta-Analysis.
Q38972951The crosstalk between long non-coding RNAs and PI3K in cancer
Q90352863The emergence of long non-coding RNAs in hepatocellular carcinoma: an update
Q36544646The lincRNA HOTAIRM1, located in the HOXA genomic region, is expressed in acute myeloid leukemia, impacts prognosis in patients in the intermediate-risk cytogenetic category, and is associated with a distinctive microRNA signature.
Q37633708The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathway
Q91451568The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia
Q57093529The long non-coding RNA landscape in juvenile myelomonocytic leukemia
Q97072562The role of Long Non-Coding RNAs (lncRNAs) and downstream signaling pathways in Leukemia progression
Q28071427Therapeutic Resistance in Acute Myeloid Leukemia: The Role of Non-Coding RNAs
Q92337654Transcriptional networks in acute myeloid leukemia
Q41910504Transcriptome profiling of patient derived xenograft models established from pediatric acute myeloid leukemia patients confirm maintenance of FLT3-ITD mutation
Q64907849Transcripts with systematic nucleotide deletion of 1-12 nucleotide in human mitochondrion suggest potential non-canonical transcription.
Q28596502Unbiased Mitoproteome Analyses Confirm Non-canonical RNA, Expanded Codon Translations
Q92459714circMYBL2, a circRNA from MYBL2, regulates FLT3 translation by recruiting PTBP1 to promote FLT3-ITD AML progression
Q90350387lncITPF Promotes Pulmonary Fibrosis by Targeting hnRNP-L Depending on Its Host Gene ITGBL1
Q47375547microRNAs and Acute Myeloid Leukemia Chemoresistance: A Mechanistic Overview

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